dehydroepiandrosterone has been researched along with Parasitemia in 6 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Parasitemia: The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of castration and subsequent replacement of dehydroepiandrosterone (DHEA) or estradiol on parasitemia, mortality and incidence of cerebral malaria (CM) was evaluated in CBA mice infected with Plasmodium berghei ANKA." | 7.73 | Estradiol, but not dehydroepiandrosterone, decreases parasitemia and increases the incidence of cerebral malaria and the mortality in plasmodium berghei ANKA-infected CBA mice. ( Carvalho, LJ; Cunha, MG; Daniel-Ribeiro, CT; do Nascimento, JL; Libonati, RM; Oliveira, SG; Santos, MV; Souza, JM, 2006) |
| "Dehydroepiandrosterone (DHEA) has long been considered as a precursor for many steroid hormones." | 5.35 | Trypanosoma cruzi: dehydroepiandrosterone (DHEA) and immune response during the chronic phase of the experimental Chagas' disease. ( Brazão, V; Caetano, LC; Caetano, LN; Caldeira, JC; Del Vecchio Filipin, M; do Prado Júnior, JC; Santello, FH; Toldo, MP, 2009) |
| "The effect of castration and subsequent replacement of dehydroepiandrosterone (DHEA) or estradiol on parasitemia, mortality and incidence of cerebral malaria (CM) was evaluated in CBA mice infected with Plasmodium berghei ANKA." | 3.73 | Estradiol, but not dehydroepiandrosterone, decreases parasitemia and increases the incidence of cerebral malaria and the mortality in plasmodium berghei ANKA-infected CBA mice. ( Carvalho, LJ; Cunha, MG; Daniel-Ribeiro, CT; do Nascimento, JL; Libonati, RM; Oliveira, SG; Santos, MV; Souza, JM, 2006) |
| "Dehydroepiandrosterone is an abundant steroid hormone secreted by the human adrenal cortex and it is considered potent immune-activator." | 1.36 | DHEA and testosterone therapies in Trypanosoma cruzi-infected rats are associated with thymic changes. ( Brazão, V; Caetano, LC; do Prado, JC; Filipin, Mdel V; Santello, FH; Toldo, MP, 2010) |
| "Dehydroepiandrosterone (DHEA) has long been considered as a precursor for many steroid hormones." | 1.35 | Trypanosoma cruzi: dehydroepiandrosterone (DHEA) and immune response during the chronic phase of the experimental Chagas' disease. ( Brazão, V; Caetano, LC; Caetano, LN; Caldeira, JC; Del Vecchio Filipin, M; do Prado Júnior, JC; Santello, FH; Toldo, MP, 2009) |
| "Treatment with melatonin, DHEA and the association showed a significant reduction in the number of blood trypomastigotes during the acute phase of infection as compared to untreated animals (P < 0." | 1.35 | Melatonin and dehydroepiandrosterone combination: does this treatment exert a synergistic effect during experimental Trypanosoma cruzi infection? ( Alonso Toldo, MP; de Albuquerque, S; do Prado, JC; Ferreira, DS; Kuehn, CC; Rodrigues Oliveira, LG; Santos, CD, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Filipin, Mdel V | 2 |
| Brazão, V | 3 |
| Caetano, LC | 3 |
| Santello, FH | 3 |
| Toldo, MP | 3 |
| Caetano, LN | 2 |
| do Prado, JC | 3 |
| Del Vecchio Filipin, M | 1 |
| Caldeira, JC | 1 |
| do Prado Júnior, JC | 1 |
| Kuehn, CC | 1 |
| Rodrigues Oliveira, LG | 1 |
| Santos, CD | 1 |
| Ferreira, DS | 1 |
| Alonso Toldo, MP | 1 |
| de Albuquerque, S | 1 |
| Pérez, AR | 1 |
| Bertoya, AA | 1 |
| Revelli, S | 1 |
| García, F | 1 |
| Libonati, RM | 1 |
| Cunha, MG | 1 |
| Souza, JM | 1 |
| Santos, MV | 1 |
| Oliveira, SG | 1 |
| Daniel-Ribeiro, CT | 1 |
| Carvalho, LJ | 1 |
| do Nascimento, JL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Etude de l'Activite (Efficacite et Tolerance) de l'Association de la Chloroquine Avec la Dehydroepiandrosterone-Sulfate (Dheas) Dans le Traitement de l'Acces Palustre Simple A Plasmodium Falciparum[NCT00442403] | Phase 3 | 200 participants | Interventional | 2002-04-30 | Suspended (stopped due to At the end of the year 2002, Cameroon switched from chloroquine to amodiaquine as first-line therapy for of uncomplicated malaria.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for dehydroepiandrosterone and Parasitemia
| Article | Year |
|---|---|
Trypanosoma cruzi: orchiectomy and dehydroepiandrosterone therapy in infected rats.
Topics: Adjuvants, Immunologic; Animals; Cell Count; Chagas Disease; Dehydroepiandrosterone; Heart; Interfer | 2008 |
Trypanosoma cruzi: dehydroepiandrosterone (DHEA) and immune response during the chronic phase of the experimental Chagas' disease.
Topics: Animals; Ascitic Fluid; Cell Proliferation; Chagas Disease; Chronic Disease; Dehydroepiandrosterone; | 2009 |
Melatonin and dehydroepiandrosterone combination: does this treatment exert a synergistic effect during experimental Trypanosoma cruzi infection?
Topics: Adjuvants, Immunologic; Animals; Antioxidants; Chagas Disease; Dehydroepiandrosterone; Drug Combinat | 2009 |
DHEA and testosterone therapies in Trypanosoma cruzi-infected rats are associated with thymic changes.
Topics: Animals; Antiprotozoal Agents; Chagas Disease; Dehydroepiandrosterone; Interleukin-12; Male; Parasit | 2010 |
A high corticosterone/DHEA-s ratio in young rats infected with Trypanosoma cruzi is associated with increased susceptibility.
Topics: Acute Disease; Animals; Chagas Disease; Corticosterone; Cytokines; Dehydroepiandrosterone; Disease S | 2011 |
Estradiol, but not dehydroepiandrosterone, decreases parasitemia and increases the incidence of cerebral malaria and the mortality in plasmodium berghei ANKA-infected CBA mice.
Topics: Animals; Brain; Causality; Dehydroepiandrosterone; Disease Models, Animal; Estradiol; Female; Immuni | 2006 |