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dehydroepiandrosterone and Optic Neuritis

dehydroepiandrosterone has been researched along with Optic Neuritis in 1 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Optic Neuritis: Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).

Research Excerpts

ExcerptRelevanceReference
"Experimental autoimmune encephalomyelitis was induced in C57/BL6 mice."1.40HE3286 reduces axonal loss and preserves retinal ganglion cell function in experimental optic neuritis. ( Ahlem, C; Dine, K; Khan, RS; Luna, E; Shindler, KS, 2014)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khan, RS1
Dine, K1
Luna, E1
Ahlem, C1
Shindler, KS1

Other Studies

1 other study available for dehydroepiandrosterone and Optic Neuritis

ArticleYear
HE3286 reduces axonal loss and preserves retinal ganglion cell function in experimental optic neuritis.
    Investigative ophthalmology & visual science, 2014, Aug-19, Volume: 55, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Axons; Dehydroepiandrosterone; Disease Models, Animal; Encephalom

2014