dehydroepiandrosterone has been researched along with Obesity in 258 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
Excerpt | Relevance | Reference |
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"The efficacy of oral dehydroepiandrosterone (DHEA) in the treatment of atrichia pubis and psychological distress in young females with central adrenal insufficiency is unknown." | 9.14 | Effects of dehydroepiandrosterone therapy on pubic hair growth and psychological well-being in adolescent girls and young women with central adrenal insufficiency: a double-blind, randomized, placebo-controlled phase III trial. ( Bettendorf, M; Binder, G; Doerr, HG; Ehrismann, M; Hartmann, MF; Heinrich, U; Keller, E; Maier, L; Meisner, C; Pfaeffle, RW; Ranke, MB; Weber, S; Wudy, SA; Zaiser, N, 2009) |
"To demonstrate that calcium channel blockers can improve insulin resistance clinically, we investigated the effects of the calcium channel blockers, amlodipine, manidipine and cilnidipine on serum levels of steroid hormones and insulin." | 9.11 | Effects of the long-acting calcium channel blockers, amlodipine, manidipine and cilnidipine on steroid hormones and insulin resistance in hypertensive obese patients. ( Miyachi, Y; Ueshiba, H, 2004) |
"6 years, height, weight, fat mass, fasting insulin concentration, insulin resistance (by HOMA-R; see text), and leptin and IGF-I levels were determined to test whether they explain the variance of the levels of dehydroepiandrosterone (DHEA) and its sulfate (DHEAS), of androstenedione, and of cortisol before and during 42 months of therapy with growth hormone." | 9.10 | Increased adrenal androgen levels in patients with Prader-Willi syndrome are associated with insulin, IGF-I, and leptin, but not with measures of obesity. ( Blum, W; Eiholzer, U; Gasser, T; Girard, J; L'Allemand, D; Rousson, V; Torresani, T, 2002) |
"To determine the clinical, hormonal, and biochemical effects of 4-6 months of metformin therapy in obese patients with polycystic ovary syndrome (PCOS)." | 9.08 | Metformin therapy improves the menstrual pattern with minimal endocrine and metabolic effects in women with polycystic ovary syndrome. ( Koivunen, RM; Martikainen, HK; Morin-Papunen, LC; Ruokonen, A, 1998) |
" Dehydroepiandrosterone (DHEA), a steroid hormone produced by the adrenal cortex, has been reported to have beneficial effects on diabetes mellitus and obesity in animal models." | 8.98 | Effect of Dehydroepiandrosterone (DHEA) on Diabetes Mellitus and Obesity. ( Aoki, K; Terauchi, Y, 2018) |
"The age-related decline in serum dehydroepiandrosterone (DHEA) and its sulfated ester (DHEA-S) has suggested that a relative deficiency of these steroids may be causally related to the development of chronic diseases generally associated with aging, including insulin resistance, obesity, cardiovascular disease, cancer, reductions of the immune defense, depression and a general deterioration in the sensation of well-being." | 8.82 | Dehydroepiandrosterone, obesity and cardiovascular disease risk: a review of human studies. ( Labrie, F; Tchernof, A, 2004) |
"Initial studies showed that dehydroepiandrosterone (DHEA) treatment in mice resulted in lower body weight gain." | 8.78 | The antiobesity effect of dehydroepiandrosterone in rats. ( Cleary, MP, 1991) |
"This study was undertaken to assess the effects of dehydroepiandrosterone (DHEA) administration and exercise training on muscular DHEA and 5α-dihydrotestosterone (DHT) levels and hyperglycemia in diet-induced obese and hyperglycemic rats." | 7.77 | Increased muscular dehydroepiandrosterone levels are associated with improved hyperglycemia in obese rats. ( Aizawa, K; Fujita, S; Iemitsu, M; Mesaki, N; Sato, K, 2011) |
" This study aimed to assess the ability of EM-652, alone or with dehydroepiandrosterone (DHEA), to prevent obesity and related metabolic abnormalities induced by an obesity-promoting diet and ovariectomy." | 7.72 | The estrogen antagonist EM-652 and dehydroepiandrosterone prevent diet- and ovariectomy-induced obesity. ( Deshaies, Y; Labrie, F; Lemieux, C; Picard, F; Richard, D, 2003) |
"The authors evaluate the effects of 2 months of treatment with 250 mg flutamide daily on adrenal steroidogenesis (ACTH test) and metabolic parameters (lipids, insulin resistance) in 12 PCOS women aged 33." | 7.72 | Flutamide suppresses adrenal steroidogenesis but has no effect on insulin resistance and secretion and lipid levels in overweight women with polycystic ovary syndrome. ( Dvoráková, K; Hill, M; Stanická, S; Stárka, L; Vondra, K; Vrbíková, J, 2004) |
"We investigated the effects of the calcium channel blocker amlodipine besilate on serum levels of adrenal androgens and insulin in 20 men with essential hypertension and obesity (age: 51." | 7.71 | Effects of amlodipine on serum levels of adrenal androgens and insulin in hypertensive men with obesity. ( Miyachi, Y; Tsuboi, K; Ueshiba, H, 2001) |
"We have evaluated serum leptin concentrations in two forms of genetic obesity." | 7.70 | Serum leptin concentrations in obese women with Down syndrome and Prader-Willi syndrome. ( Cento, RM; Lanzone, A; Napolitano, V; Proto, C; Ragusa, L; Reitano, S; Spada, RS, 1999) |
"To assess the effect of weight reduction on serum dehydroepiandrosterone (DHEA)-sulfate, insulin, and glucose, these parameters were assessed in 18 men and 29 women before and after weight loss achieved by a 2-month 1000-1400 kcal diet." | 7.69 | Disparate effects of weight reduction by diet on serum dehydroepiandrosterone-sulfate levels in obese men and women. ( Beer, NA; Beer, RM; Jakubowicz, DJ; Nestler, JE, 1995) |
"We examined the effects of an oral glucose load on plasma insulin, androgens, and beta-endorphin (beta EP) concentrations in patients carefully selected as having polycystic ovary syndrome (PCOS) and normal glucose tolerance." | 7.69 | Insulin, C-peptide, androgens, and beta-endorphin response to oral glucose in patients with polycystic ovary syndrome. ( Barini, A; Dell'Acqua, S; Liberale, I; Lucisano, A; Martino, G; Menini, E; Tropeano, G; Vuolo, IP, 1994) |
"Although antiobesity effect of dehydroepiandrosterone (DHEA) has been reported in rats, it remains unclear whether the effect is brought about by itself or mediated by sex steroids converted from DHEA in gonads." | 7.69 | The antiobesity effect of dehydroepiandrosterone in castrated or noncastrated obese Zucker male rats. ( Haji, M; Ishibashi, K; Nawata, H; Takayanagi, R; Taniguchi, S; Yanase, T, 1995) |
" In this study, dehydroepiandrosterone's effect at decreasing food intake and body weight in the obese Zucker rat was investigated." | 7.68 | Effect of dehydroepiandrosterone on neurotransmitter levels and appetite regulation of the obese Zucker rat. The Obesity Research Program. ( Abadie, JM; Browne, ES; Correa, G; Porter, JR; Svec, F; Wright, B, 1993) |
"We hypothesize that dehydroepiandrosterone sulfate dampens the effect of insulin resistance, which in turn is reflected in apolipoprotein profiles in women with hirsutism/hyperandrogenism." | 7.68 | Lipoprotein abnormalities in hirsute women. II. Compensatory responses of insulin resistance and dehydroepiandrosterone sulfate with obesity. ( Alaupovic, P; Givens, JR; Parker, IJ; Wild, RA, 1992) |
"The objective of this study was to define the relationship among the circulating insulin level (IRI), the MCR of dehydroepiandrosterone (MCR-D), and the production rate of DHEA (PR-D) in 10 women with the polycystic ovary syndrome and acanthosis nigricans (PCOS-AN)." | 7.68 | Bimodal correlation between the circulating insulin level and the production rate of dehydroepiandrosterone: positive correlation in controls and negative correlation in the polycystic ovary syndrome with acanthosis nigricans. ( Farah, MJ; Givens, JR; Kitabchi, AE, 1990) |
"Previous studies showed that administration of dehydroepiandrosterone (DHEA) to lean and genetically obese Zucker rats reduced body weight." | 7.68 | Effects of dehydroepiandrosterone treatment in rats with diet-induced obesity. ( Cleary, MP; Ihnen, JS; Levin, BE; Mohan, PF, 1990) |
"To investigate the glucagon status of women with polycystic ovary syndrome (PCO) and to relate this to serum concentrations of insulin, androgens and SHBG, 44 women with PCO and 23 control subjects underwent a 75-g oral glucose tolerance test." | 7.68 | Glucagon in women with polycystic ovary syndrome (PCO): relationship to abnormalities of insulin and androgens. ( Elstein, M; Golland, IM; Laing, I; Shalet, SM; Vaughan Williams, CA, 1990) |
"Two metabolites of the adrenal steroid dehydroepiandrosterone (DHEA), 3 alpha-hydroxyetiocholanolone and 3 beta-hydroxyetiocholanolone, were found to have antiobesity properties with respect to both prevention of the development of obesity as well as weight reduction after obesity was established." | 7.67 | Antiobesity effects of etiocholanolones in diabetes (db), viable yellow (Avy), and normal mice. ( Coleman, DL, 1985) |
"To study the effect of obesity on the metabolism of adrenal androgens not bound to testosterone-estradiol-binding globulin, the MCRs of delta 4-androstenedione (A) and dehydroepiandrosterone (DHEA) were determined using constant infusion of unlabeled steroids to steady state in 8 normal weight and 19 obese nonhirsute eumenorrheic women." | 7.67 | Maintenance of normal circulating levels of delta 4-androstenedione and dehydroepiandrosterone in simple obesity despite increased metabolic clearance rates: evidence for a servo-control mechanism. ( Bittle, JB; Givens, JR; Judge, D; Karas, JG; Kitabchi, AE; Komindr, S; Kurtz, BR; Stevens, MD, 1987) |
"We investigated the anti-obesity effects of the adrenal androgen, dehydroepiandrosterone (DHEA), on genetically predisposed obese lethal yellow mice (Ay/Aw)." | 7.67 | Effects of dehydroepiandrosterone on obesity and glucose-6-phosphate dehydrogenase activity in the lethal yellow mouse (strain 129/Sv-Ay/Aw). ( Granholm, NH; Staber, LD; Wilkin, PJ, 1987) |
", food restriction and chronic dehydroepiandrosterone (DHEA) treatment), or a production of obesity by the presence of the ob (obese) gene or by gold thioglucose-induced hyperphagia alter the rate of binding of 3H-7,12-dimethylbenz(a)anthracene (3H-DMBA) to mouse skin deoxyribonucleic acid (DNA)." | 7.66 | Effect of food restriction, dehydroepiandrosterone, or obesity on the binding of 3H-7,12-dimethylbenz(a)anthracene to mouse skin DNA. ( Pashko, LL; Schwartz, AG, 1983) |
"Late promotion of breast cancer in postmenopausal women may be stimulated by prolonged intake of DHEA, and the risk may be increased by the endocrine abnormality associated with pre-existing abdominal obesity." | 6.40 | Dietary supplements of dehydroepiandrosterone in relation to breast cancer risk. ( Stoll, BA, 1999) |
"Obesity is a heterogeneous condition and not every obese patient is at increased risk of cardiovascular diseases (CVD)." | 6.39 | Obesity and metabolic complications: contribution of dehydroepiandrosterone and other steroid hormones. ( Bélanger, A; Després, JP; Labrie, F; Tchernof, A, 1996) |
"In this study, the effects of DHEA treatment on insulin sensitivity were investigated in genetically obese Zucker rats, an animal model of insulin resistance, using the euglycemic clamp technique." | 5.30 | Dehydroepiandrosterone decreases serum tumor necrosis factor-alpha and restores insulin sensitivity: independent effect from secondary weight reduction in genetically obese Zucker fatty rats. ( Kimura, M; Kiuchi, Y; Sekihara, H; Tanaka, S; Yamada, Y; Yamakawa, T, 1998) |
"Dehydroepiandrosterone has previously been shown to prevent weight gain in growing lean and obese mice and rats." | 5.27 | Anti-obesity effect of two different levels of dehydroepiandrosterone in lean and obese middle-aged female Zucker rats. ( Cleary, MP; Zisk, JF, 1986) |
"Dehydroepiandrosterone did not suppress appetite and had no apparent toxic effects at the doses used, and its weight controlling effects were reversible upon withdrawal of treatment." | 5.26 | Prevention of obesity in Avy/a mice by dehydroepiandrosterone. ( Acton, JM; Allan, JA; Greenberg, MM; Pearson, DV; Yen, TT, 1977) |
"The efficacy of oral dehydroepiandrosterone (DHEA) in the treatment of atrichia pubis and psychological distress in young females with central adrenal insufficiency is unknown." | 5.14 | Effects of dehydroepiandrosterone therapy on pubic hair growth and psychological well-being in adolescent girls and young women with central adrenal insufficiency: a double-blind, randomized, placebo-controlled phase III trial. ( Bettendorf, M; Binder, G; Doerr, HG; Ehrismann, M; Hartmann, MF; Heinrich, U; Keller, E; Maier, L; Meisner, C; Pfaeffle, RW; Ranke, MB; Weber, S; Wudy, SA; Zaiser, N, 2009) |
"To demonstrate that calcium channel blockers can improve insulin resistance clinically, we investigated the effects of the calcium channel blockers, amlodipine, manidipine and cilnidipine on serum levels of steroid hormones and insulin." | 5.11 | Effects of the long-acting calcium channel blockers, amlodipine, manidipine and cilnidipine on steroid hormones and insulin resistance in hypertensive obese patients. ( Miyachi, Y; Ueshiba, H, 2004) |
"Dehydroepiandrosterone (DHEA) administration has been shown to reduce accumulation of abdominal visceral fat and protect against insulin resistance in laboratory animals, but it is not known whether DHEA decreases abdominal obesity in humans." | 5.11 | Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial. ( Holloszy, JO; Villareal, DT, 2004) |
"6 years, height, weight, fat mass, fasting insulin concentration, insulin resistance (by HOMA-R; see text), and leptin and IGF-I levels were determined to test whether they explain the variance of the levels of dehydroepiandrosterone (DHEA) and its sulfate (DHEAS), of androstenedione, and of cortisol before and during 42 months of therapy with growth hormone." | 5.10 | Increased adrenal androgen levels in patients with Prader-Willi syndrome are associated with insulin, IGF-I, and leptin, but not with measures of obesity. ( Blum, W; Eiholzer, U; Gasser, T; Girard, J; L'Allemand, D; Rousson, V; Torresani, T, 2002) |
"Dehydroepiandrosterone (DHEA) has been shown to have antiobesity activity in rodents and spontaneously obese dogs." | 5.08 | The effect of dehydroepiandrosterone combined with a low-fat diet in spontaneously obese dogs: a clinical trial. ( Kurzman, ID; MacEwen, EG; Miller, JB; Panciera, DL, 1998) |
"To determine the clinical, hormonal, and biochemical effects of 4-6 months of metformin therapy in obese patients with polycystic ovary syndrome (PCOS)." | 5.08 | Metformin therapy improves the menstrual pattern with minimal endocrine and metabolic effects in women with polycystic ovary syndrome. ( Koivunen, RM; Martikainen, HK; Morin-Papunen, LC; Ruokonen, A, 1998) |
"Etiocholanedione (ED), a natural metabolite of dehydroepiandrosterone, has antiobesity effects in animals when given orally and is nontoxic." | 5.07 | A randomized double-blind crossover study of the antiobesity effects of etiocholanedione. ( Heymsfield, SB; Lichtman, S; Strain, GW; Zumoff, B, 1994) |
" Dehydroepiandrosterone (DHEA), a steroid hormone produced by the adrenal cortex, has been reported to have beneficial effects on diabetes mellitus and obesity in animal models." | 4.98 | Effect of Dehydroepiandrosterone (DHEA) on Diabetes Mellitus and Obesity. ( Aoki, K; Terauchi, Y, 2018) |
"The age-related decline in serum dehydroepiandrosterone (DHEA) and its sulfated ester (DHEA-S) has suggested that a relative deficiency of these steroids may be causally related to the development of chronic diseases generally associated with aging, including insulin resistance, obesity, cardiovascular disease, cancer, reductions of the immune defense, depression and a general deterioration in the sensation of well-being." | 4.82 | Dehydroepiandrosterone, obesity and cardiovascular disease risk: a review of human studies. ( Labrie, F; Tchernof, A, 2004) |
"Initial studies showed that dehydroepiandrosterone (DHEA) treatment in mice resulted in lower body weight gain." | 4.78 | The antiobesity effect of dehydroepiandrosterone in rats. ( Cleary, MP, 1991) |
"Low birth size (BS) and obesity have been associated with higher dehydroepiandrosterone sulfate (DHEAS) levels in childhood, insulin acting as a mediator, despite contradictory findings." | 4.12 | Association of dehydroepiandrosterone sulfate, birth size, adiposity and cardiometabolic risk factors in 7-year-old children. ( Barros, H; Fontoura, M; Guimarães, JT; Santos, AC; Santos-Silva, R, 2022) |
"Obesity and mild unmedicated metabolic risk factors alter the circulating steroid profile and bias the estimation of reference limits for testosterone, dihydrotestosterone, cortisol and corticosterone." | 3.96 | Impact of age, body weight and metabolic risk factors on steroid reference intervals in men. ( Baccini, M; Di Dalmazi, G; Fanelli, F; Fazzini, A; Gambineri, A; Mezzullo, M; Pagotto, U; Pelusi, C; Repaci, A; Vicennati, V, 2020) |
"Substantial evidence has linked dehydroepiandrosterone (DHEA) levels to the anti-obesity and anti-diabetic effects of exercise." | 3.96 | Dehydroepiandrosterone activates 5'-adenosine monophosphate-activated protein kinase and suppresses lipid accumulation and adipocyte differentiation in 3T3-L1 cells. ( Hashimoto, T; Hayashi, T; Iwanaka, N; Kido, K; Mori, R; Narusawa, R; Sato, K; Yokokawa, T, 2020) |
" Body weight, retroperitoneal fat depot weight, serum glucose, insulin, and leptin levels, and hepatic lipids were measured." | 3.81 | Sex-related differences in the effects of high-fat diets on DHEA-treated rats. ( Arbo, BD; Cecconello, AL; Hoefel, AL; Kucharski, LC; Marques, CV; Osterkamp, G; Ribeiro, MF; Trapp, M, 2015) |
" Dehydroepiandrosterone (DHEA), a major circulating adrenal steroid and dietary supplement, demonstrates antiobesity, anti-inflammatory, GC-opposing and immune-modulating activity when administered to rodents." | 3.77 | A potential role for 5-androstene-3β,7β,17β-triol in obesity and metabolic syndrome. ( Ahlem, CN; Auci, DL; Frincke, JM; Kennedy, MR; Page, TM; Reading, CL, 2011) |
"This study was undertaken to assess the effects of dehydroepiandrosterone (DHEA) administration and exercise training on muscular DHEA and 5α-dihydrotestosterone (DHT) levels and hyperglycemia in diet-induced obese and hyperglycemic rats." | 3.77 | Increased muscular dehydroepiandrosterone levels are associated with improved hyperglycemia in obese rats. ( Aizawa, K; Fujita, S; Iemitsu, M; Mesaki, N; Sato, K, 2011) |
"A major achievement from 500 million years of evolution is the establishment of a high secretion rate of dehydroepiandrosterone (DHEA) by the human adrenal glands coupled with the indroduction of menopause which stops secretion of estrogens by the ovary." | 3.76 | DHEA, important source of sex steroids in men and even more in women. ( Labrie, F, 2010) |
" Dehydroepiandrosterone (DHEA) is an over-the-counter dietary supplement used as an immunomodulating, anti-depressant, anti-aging, anti-cardiovascular disease, and anti-cancer agent and anti-obesity supplement." | 3.76 | Dehydroepiandrosterone intake protects against 7,12-dimethylbenz(a)anthracene-induced mammary tumor development in the obese Zucker rat model. ( Hakkak, R; Jo, CH; Korourian, S; MacLeod, S; Shaaf, S, 2010) |
" This study aimed to assess the ability of EM-652, alone or with dehydroepiandrosterone (DHEA), to prevent obesity and related metabolic abnormalities induced by an obesity-promoting diet and ovariectomy." | 3.72 | The estrogen antagonist EM-652 and dehydroepiandrosterone prevent diet- and ovariectomy-induced obesity. ( Deshaies, Y; Labrie, F; Lemieux, C; Picard, F; Richard, D, 2003) |
"Increased plasma levels of allopregnenolone (3alpha,5alpha-tetrahydroprogesterone [3alpha,5alpha-THP]), dehydroepiandrosterone (DHEA), and DHEA sulphate (DHEA-S) have been reported in patients with anorexia nervosa or bulimia nervosa." | 3.72 | Circulating levels of neuroactive steroids in patients with binge eating disorder: a comparison with nonobese healthy controls and non-binge eating obese subjects. ( Colurcio, B; De Filippis, G; Genazzani, AR; Luisi, M; Maj, M; Monteleone, P, 2003) |
" The frequency of obesity and the correlation between dehydroepiandrosterone sulphate levels and body mass index suggest that body weight is involved in the onset of adrenarche." | 3.72 | Premature pubarche as an indicator of how body weight influences the onset of adrenarche. ( Brauner, R; Charkaluk, ML; Trivin, C, 2004) |
"The authors evaluate the effects of 2 months of treatment with 250 mg flutamide daily on adrenal steroidogenesis (ACTH test) and metabolic parameters (lipids, insulin resistance) in 12 PCOS women aged 33." | 3.72 | Flutamide suppresses adrenal steroidogenesis but has no effect on insulin resistance and secretion and lipid levels in overweight women with polycystic ovary syndrome. ( Dvoráková, K; Hill, M; Stanická, S; Stárka, L; Vondra, K; Vrbíková, J, 2004) |
" Anthropometric measurements, staging of pubertal maturation, and clinical manifestations of hyperandrogenism were assessed, as well as measurement of serum levels of testosterone, dehydroepiandrosterone sulfate (DHEAS), sex hormone-binding globulin (SHBG), and free androgen index (FAI)." | 3.72 | Physical growth and endocrinal disorders during pubertal maturation in girls with epilepsy. ( Abd El-Basset, FZ; El Barbary, NS; El-Khayat, HA; Hakky, SM; Mohamed, MS; Nassef, NM; Tohamy, SM; Tomoum, HY; Zaky, AA, 2004) |
"We investigated the effects of the calcium channel blocker amlodipine besilate on serum levels of adrenal androgens and insulin in 20 men with essential hypertension and obesity (age: 51." | 3.71 | Effects of amlodipine on serum levels of adrenal androgens and insulin in hypertensive men with obesity. ( Miyachi, Y; Tsuboi, K; Ueshiba, H, 2001) |
" Dehydroepiandrosterone (DHEA) and AA, like the thiazolidinedione drugs that decrease insulin resistance (IR), are peroxisome proliferators." | 3.71 | Dehydroepiandrosterone alters phospholipid profiles in Zucker rat muscle tissue. ( Abadie, JM; Malcom, GT; Porter, JR; Svec, F, 2001) |
"We have evaluated serum leptin concentrations in two forms of genetic obesity." | 3.70 | Serum leptin concentrations in obese women with Down syndrome and Prader-Willi syndrome. ( Cento, RM; Lanzone, A; Napolitano, V; Proto, C; Ragusa, L; Reitano, S; Spada, RS, 1999) |
"The purpose of this study was to determine if the antiobesity actions of dehydroepiandrosterone (DHEA) observed in vivo are due to an influence on the proliferation and differentiation of primary cultures of stromal-vascular (SV) cells isolated from human adipose tissue." | 3.70 | Dehydroepiandrosterone alters the growth of stromal vascular cells from human adipose tissue. ( Geigerman, C; Lea-Currie, YR; McIntosh, MK; Patseavouras, L, 1999) |
" When administered to obese, hypercorticosteronemic Zucker rats, it causes a diminution of food intake and a reduction in their rate of weight gain." | 3.69 | The effect of DHEA given chronically to Zucker rats. ( Browne, E; Hilton, CW; Porter, JR; Svec, F; Wright, B, 1995) |
"To assess the effect of weight reduction on serum dehydroepiandrosterone (DHEA)-sulfate, insulin, and glucose, these parameters were assessed in 18 men and 29 women before and after weight loss achieved by a 2-month 1000-1400 kcal diet." | 3.69 | Disparate effects of weight reduction by diet on serum dehydroepiandrosterone-sulfate levels in obese men and women. ( Beer, NA; Beer, RM; Jakubowicz, DJ; Nestler, JE, 1995) |
" Obesity itself exerted effects on endocrine variables, with the net result of a reduced LH/FSH ratio and lower serum levels of androstenedione and SHBG in both groups; obesity was associated with increased levels of DHEAS, testosterone and FAI exclusively in the women with PCOS." | 3.69 | The independent effects of polycystic ovary syndrome and obesity on serum concentrations of gonadotrophins and sex steroids in premenopausal women. ( Bergh, T; Gennarelli, G; Holte, J; Wide, L, 1994) |
"We examined the effects of an oral glucose load on plasma insulin, androgens, and beta-endorphin (beta EP) concentrations in patients carefully selected as having polycystic ovary syndrome (PCOS) and normal glucose tolerance." | 3.69 | Insulin, C-peptide, androgens, and beta-endorphin response to oral glucose in patients with polycystic ovary syndrome. ( Barini, A; Dell'Acqua, S; Liberale, I; Lucisano, A; Martino, G; Menini, E; Tropeano, G; Vuolo, IP, 1994) |
"Dehydroepiandrosterone (DHEA) decreases body weight and food intake of the obese Zucker rat, a model of youth-onset obesity associated with hyperphagia." | 3.69 | The effect of discontinuing dehydroepiandrosterone supplementation on Zucker rat food intake and hypothalamic neurotransmitters. ( Abadie, JM; Browne, ES; Porter, JR; Svec, F; Wright, BE, 1995) |
" Among these, we cite the problem of whether the age-related decrease in testosterone (T) levels is an intrinsic aging phenomenon or is a sequel of previous illness, the mechanisms underlying the increase in sex hormone-binding globulin (SHBG)-binding capacity in aging men and the supranormal capacity observed immediately after a weight-reducing diet, and the role of insulin in the age-associated decrease in dehydroepiandrosterone (sulfate) [DHEA (DHEAS)] levels." | 3.69 | Influence of some biological indexes on sex hormone-binding globulin and androgen levels in aging or obese males. ( Giagulli, VA; Kaufman, JM; Vermeulen, A, 1996) |
"Although antiobesity effect of dehydroepiandrosterone (DHEA) has been reported in rats, it remains unclear whether the effect is brought about by itself or mediated by sex steroids converted from DHEA in gonads." | 3.69 | The antiobesity effect of dehydroepiandrosterone in castrated or noncastrated obese Zucker male rats. ( Haji, M; Ishibashi, K; Nawata, H; Takayanagi, R; Taniguchi, S; Yanase, T, 1995) |
"To investigate whether dehydroepiandrosterone (DHEA), an adrenal/gonadal androgen, can act centrally to reduce energy intake in a model of genetic obesity, the Zucker fatty rat." | 3.69 | Central effects of dehydroepiandrosterone in Zucker rats. ( Porter, JR; Svec, F; Wright, BE, 1995) |
"To evaluate the relative or discriminatory usefulness of sex hormone binding globulin (SHBG), dehydroepiandrosterone sulphate (DHEAS) and insulin like growth factor binding protein 1 (IGFBP-1) as markers of insulin resistance and to estimate the tissue sensitivity to insulin by means of the insulin tolerance test (ITT) and the frequently sampled i." | 3.69 | [Biochemical markers and methods to assess insulin resistance in normal, obese and hyperandrogenic women]. ( Calvillán, M; Castillo, T; Durruty, P; López, G; Muñoz, S; Sir, T, 1997) |
" In this study, dehydroepiandrosterone's effect at decreasing food intake and body weight in the obese Zucker rat was investigated." | 3.68 | Effect of dehydroepiandrosterone on neurotransmitter levels and appetite regulation of the obese Zucker rat. The Obesity Research Program. ( Abadie, JM; Browne, ES; Correa, G; Porter, JR; Svec, F; Wright, B, 1993) |
"Severe obesity is known to reduce either dehydroepiandrosterone circulating levels or growth hormone (GH) and insulin-like growth factor-1 (IGF-1) secretion." | 3.68 | Insulin-like growth factor-1 (IGF-1) and dehydroepiandrosterone sulphate in obese women. ( Cignarelli, M; Cospite, MR; De Pergola, G; Garruti, G; Giagulli, VA; Giorgino, F; Giorgino, R, 1993) |
"Dehydroepiandrosterone (DHEA) reduces weight gain in the hypercorticosteronemic Zucker fatty rat, an animal model of genetic obesity." | 3.68 | Antiglucocorticoid action of dehydroepiandrosterone in young obese Zucker rats. ( Browne, ES; Porter, JR; Svec, F; Wright, BE, 1992) |
"As in hyperandrogenicity there generally exists evidence for increased 5 alpha-reductase activity, we measured, as parameters of 5 alpha-reductase activity, plasma levels of 5 alpha-androstane-3 alpha,17 beta-diol glucuronide (ADG) and androsterone glucuronide (ADTG) as well as their precursor levels in obese women without hirsutism, obese hirsute women, non-obese hirsute women, and non-obese, non-hirsute women." | 3.68 | Increased free testosterone but normal 5 alpha-reduced testosterone metabolites in obese premenopausal women. ( Abbaticchio, G; Cignarelli, M; De Pergola, G; Giagulli, VA; Giorgino, F; Giorgino, R; Vermeulen, A, 1992) |
"We hypothesize that dehydroepiandrosterone sulfate dampens the effect of insulin resistance, which in turn is reflected in apolipoprotein profiles in women with hirsutism/hyperandrogenism." | 3.68 | Lipoprotein abnormalities in hirsute women. II. Compensatory responses of insulin resistance and dehydroepiandrosterone sulfate with obesity. ( Alaupovic, P; Givens, JR; Parker, IJ; Wild, RA, 1992) |
"Dehydroepiandrosterone (DHEA) has an anti-obesity effect in rodents and reduces body fat in normal men." | 3.68 | Low dehydroepiandrosterone circulating levels in premenopausal obese women with very high body mass index. ( Cignarelli, M; Cospite, MR; De Pergola, G; Garruti, G; Giagulli, VA; Giorgino, F; Giorgino, R, 1991) |
"Hyperestronemia may be central to the development of polycystic ovary syndrome." | 3.68 | Sex steroids, adiposity and smoking in the pathogenesis of idiopathic hirsutism and polycystic ovary syndrome. ( Byrne, B; Conroy, R; Cunningham, S; Igoe, D; McKenna, TJ, 1991) |
"In a previous report we found extreme hyperinsulinemia associated with high testosterone levels in patients with polycystic ovarian syndrome (PCO) and normal insulin levels in a small group of patients with elevated dehydroepiandrosterone (DHEA)." | 3.68 | Role of adrenal and gonadal androgens in insulin action and metabolism. ( Buffington, CK; Givens, J; Inouye, H; Kitabchi, AE, 1991) |
"The objective of this study was to define the relationship among the circulating insulin level (IRI), the MCR of dehydroepiandrosterone (MCR-D), and the production rate of DHEA (PR-D) in 10 women with the polycystic ovary syndrome and acanthosis nigricans (PCOS-AN)." | 3.68 | Bimodal correlation between the circulating insulin level and the production rate of dehydroepiandrosterone: positive correlation in controls and negative correlation in the polycystic ovary syndrome with acanthosis nigricans. ( Farah, MJ; Givens, JR; Kitabchi, AE, 1990) |
"Previous studies showed that administration of dehydroepiandrosterone (DHEA) to lean and genetically obese Zucker rats reduced body weight." | 3.68 | Effects of dehydroepiandrosterone treatment in rats with diet-induced obesity. ( Cleary, MP; Ihnen, JS; Levin, BE; Mohan, PF, 1990) |
"To investigate the glucagon status of women with polycystic ovary syndrome (PCO) and to relate this to serum concentrations of insulin, androgens and SHBG, 44 women with PCO and 23 control subjects underwent a 75-g oral glucose tolerance test." | 3.68 | Glucagon in women with polycystic ovary syndrome (PCO): relationship to abnormalities of insulin and androgens. ( Elstein, M; Golland, IM; Laing, I; Shalet, SM; Vaughan Williams, CA, 1990) |
"Two metabolites of the adrenal steroid dehydroepiandrosterone (DHEA), 3 alpha-hydroxyetiocholanolone and 3 beta-hydroxyetiocholanolone, were found to have antiobesity properties with respect to both prevention of the development of obesity as well as weight reduction after obesity was established." | 3.67 | Antiobesity effects of etiocholanolones in diabetes (db), viable yellow (Avy), and normal mice. ( Coleman, DL, 1985) |
"We investigated the anti-obesity effects of the adrenal androgen, dehydroepiandrosterone (DHEA), on genetically predisposed obese lethal yellow mice (Ay/Aw)." | 3.67 | Effects of dehydroepiandrosterone on obesity and glucose-6-phosphate dehydrogenase activity in the lethal yellow mouse (strain 129/Sv-Ay/Aw). ( Granholm, NH; Staber, LD; Wilkin, PJ, 1987) |
"Lean and obese Zucker rats, 7-8 wk of age, were treated with dehydroepiandrosterone (DHEA) for either 3 or 7 days to determine the initial cellular event(s) that might be responsible for the antiobesity activity of DHEA." | 3.67 | Effect of short-term DHEA administration on liver metabolism of lean and obese rats. ( Cleary, MP; Mohan, PF, 1988) |
", food restriction and chronic dehydroepiandrosterone (DHEA) treatment), or a production of obesity by the presence of the ob (obese) gene or by gold thioglucose-induced hyperphagia alter the rate of binding of 3H-7,12-dimethylbenz(a)anthracene (3H-DMBA) to mouse skin deoxyribonucleic acid (DNA)." | 3.66 | Effect of food restriction, dehydroepiandrosterone, or obesity on the binding of 3H-7,12-dimethylbenz(a)anthracene to mouse skin DNA. ( Pashko, LL; Schwartz, AG, 1983) |
"Childhood obesity is associated with advanced bone age (BA)." | 2.84 | Determinants of Advanced Bone Age in Childhood Obesity . ( Ballieux, BEPB; de Groot, CJ; Kroon, HM; Rings, EHHM; van den Akker, ELT; van den Berg, A; Wit, JM, 2017) |
"Nitrendipine treatment 1) lowered fasting serum insulin from 265 +/- 24 to 194 +/- 22 pmol/L (P < 0." | 2.67 | Effects of nitrendipine on glucose tolerance and serum insulin and dehydroepiandrosterone sulfate levels in insulin-resistant obese and hypertensive men. ( Arocha, IR; Beer, NA; Beer, RM; Jakubowicz, DJ; Nestler, JE, 1993) |
"Amlodipine treatment 1) lowered fasting serum insulin (from 273 +/- 19 to 200 +/- 17 pmol/L; P < 0." | 2.67 | The calcium channel blocker amlodipine raises serum dehydroepiandrosterone sulfate and androstenedione, but lowers serum cortisol, in insulin-resistant obese and hypertensive men. ( Beer, NA; Beer, RM; Jakubowicz, DJ; Nestler, JE, 1993) |
"Some risk factors of breast cancer development, including obesity, have also been postulated to interact with steroid metabolising pathways." | 2.52 | The intracrinology of breast cancer. ( McNamara, KM; Sasano, H, 2015) |
"Type 2 diabetes mellitus is increasing globally and is an established risk factor for the development of atherosclerotic vascular disease." | 2.43 | Androgens, insulin resistance and vascular disease in men. ( Channer, KS; Jones, TH; Kapoor, D; Malkin, CJ, 2005) |
"Obesity is an issue that is increasingly affecting ageing men." | 2.41 | Impact of obesity on hypogonadism in the andropause. ( Pu, SJ; Tan, RS, 2002) |
"Late promotion of breast cancer in postmenopausal women may be stimulated by prolonged intake of DHEA, and the risk may be increased by the endocrine abnormality associated with pre-existing abdominal obesity." | 2.40 | Dietary supplements of dehydroepiandrosterone in relation to breast cancer risk. ( Stoll, BA, 1999) |
"In some breast cancer cell lines in a low oestrogen milieu DHEA has an oestradiol-like effect, stimulating tumour growth, whereas in oestradiol abundance DHEA antagonises the growth-stimulating effect of oestradiol." | 2.39 | Physiological importance of dehydroepiandrosterone. ( Ebeling, P; Koivisto, VA, 1994) |
"Obesity is a heterogeneous condition and not every obese patient is at increased risk of cardiovascular diseases (CVD)." | 2.39 | Obesity and metabolic complications: contribution of dehydroepiandrosterone and other steroid hormones. ( Bélanger, A; Després, JP; Labrie, F; Tchernof, A, 1996) |
"Exercise ameliorates nonalcoholic fatty liver disease (NAFLD) by inducing phenotypic changes in Kupffer cells (KCs)." | 1.62 | Prevention of non-alcoholic steatohepatitis by long-term exercise via the induction of phenotypic changes in Kupffer cells of hyperphagic obese mice. ( Komine, S; Miura, I; Mizokami, Y; Oh, S; Okada, K; Shoda, J; Suzuki, H; Uchida, F; Wada, S; Warabi, E, 2021) |
"Dehydroepiandrosterone (DHEA) is an adrenal steroid hormone that is a precursor of sexual hormones." | 1.48 | Dehydroepiandrosterone supplementation is not beneficial in the late postmenopausal period in diet-induced obese rats. ( Curi, R; da Cunha Araujo, LC; de Oliveira Carvalho, CR; Ribeiro, LM; Teixeira, CJ; Veras, K, 2018) |
"Dehydroepiandrosterone (DHEA) has been reported to protect against the development of obesity." | 1.30 | DHEA protects against visceral obesity and muscle insulin resistance in rats fed a high-fat diet. ( Chen, M; Han, DH; Hansen, PA; Holloszy, JO; Nolte, LA, 1997) |
"Hyperandrogenism was observed in women with upper-body obesity, as evident by significantly elevated free testosterone (P < ." | 1.30 | Hyperinsulinemia and sex hormones in healthy premenopausal women: relative contribution of obesity, obesity type, and duration of obesity. ( Ivandić, A; Jurić, M; Prpić-Krizevac, I; Sucić, M, 1998) |
"In this study, the effects of DHEA treatment on insulin sensitivity were investigated in genetically obese Zucker rats, an animal model of insulin resistance, using the euglycemic clamp technique." | 1.30 | Dehydroepiandrosterone decreases serum tumor necrosis factor-alpha and restores insulin sensitivity: independent effect from secondary weight reduction in genetically obese Zucker fatty rats. ( Kimura, M; Kiuchi, Y; Sekihara, H; Tanaka, S; Yamada, Y; Yamakawa, T, 1998) |
"Diltiazem treatment was associated with reductions in fasting serum insulin levels in both the men (from 91 +/- 14 to 56 +/- 12 pmol/L; P < 0." | 1.29 | Disparate effects of insulin reduction with diltiazem on serum dehydroepiandrosterone sulfate levels in obese hypertensive men and women. ( Beer, NA; Beer, RM; Jakubowicz, DJ; Nestler, JE, 1994) |
"Since upper body obesity is characterized by androgen excess, a relationship between body fat distribution, sex hormones, RMR and indices of thermogenesis was studied." | 1.29 | Sex hormones, body fat distribution, resting metabolic rate and glucose-induced thermogenesis in premenopausal obese women. ( De Leeuw, IH; Van Gaal, LF; Vansant, GA; Vanuytsel, JL, 1994) |
"However, PCO patients with NIDDM differed from those without diabetes in that they had elevated basal and corticotropin-stimulated adrenal steroids (cortisol, dehydroepiandrosterone [DHEA], dehydroepiandrosterone sulfate [DHEAS])." | 1.29 | Enhanced adrenocortical activity as a contributing factor to diabetes in hyperandrogenic women. ( Buffington, CK; Givens, JR; Kitabchi, AE, 1994) |
"Insulin resistance and its attendant hyperinsulinemia has been linked with hyperandrogenism." | 1.29 | Serum androgens in hyperinsulinemic Pima Indian and obese Caucasian women and their response to short-term insulin infusion. ( Berkowitz, AS; Bogardus, C; Charles, MA; Nader, S; Saad, MF, 1993) |
"In 68 men with benign prostatic hyperplasia, we evaluated the association between obesity and prostatic enlargement, as well as changes in serum levels of oestradiol, testosterone, dihydroepiandrosterone and dihydroepiandrosterone sulphate." | 1.29 | Effect of obesity on prostatic hyperplasia: its relation to sex steroid levels. ( Arikan, N; Aydos, K; Küpeli, B; Küpeli, S; Müftüoğlu, YZ; Soygür, T, 1996) |
"Androstenedione was positively correlated with WHR (r: 0." | 1.29 | Body fat accumulation is possibly responsible for lower dehydroepiandrosterone circulating levels in premenopausal obese women. ( Armellini, F; Bosello, O; De Pergola, G; Giorgino, F; Giorgino, R; Pannacciulli, N; Perrini, S; Sciaraffia, M; Turcato, E; Zamboni, M, 1996) |
"Androstenedione was increased in the prepubertal group before and normal after weight loss; no significant difference was found in the other group." | 1.27 | Adrenal androgens in obese boys before and after weight loss. ( Corda, R; Faedda, A; Fanni, V; Loche, S; Nurchi, AM; Pintor, C, 1984) |
"Their insulin resistance was significantly greater than that in a control group with comparable obesity." | 1.27 | Obesity, acanthosis nigricans, insulin resistance, and hyperandrogenemia: pediatric perspective and natural history. ( Cavallo, A; Meyer, WJ; Peters, EJ; Prince, MJ; Richards, GE; Smith, ER; Stuart, CA, 1985) |
"Previous work has demonstrated that chronic administration of dehydroepiandrosterone (DHEA) to obese Zucker rats reduces the severity of hyperinsulinemia that is usually present." | 1.27 | Glucose metabolism in isolated adipocytes from lean and obese Zucker rats following treatment with dehydroepiandrosterone. ( Cleary, MP; Muller, S, 1985) |
"Dehydroepiandrosterone did not suppress appetite and had no apparent toxic effects at the doses used, and its weight controlling effects were reversible upon withdrawal of treatment." | 1.26 | Prevention of obesity in Avy/a mice by dehydroepiandrosterone. ( Acton, JM; Allan, JA; Greenberg, MM; Pearson, DV; Yen, TT, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 67 (25.97) | 18.7374 |
1990's | 103 (39.92) | 18.2507 |
2000's | 45 (17.44) | 29.6817 |
2010's | 32 (12.40) | 24.3611 |
2020's | 11 (4.26) | 2.80 |
Authors | Studies |
---|---|
Pereira, A | 1 |
Merino, PM | 1 |
Santos, JL | 1 |
Iñiguez, G | 1 |
Cutler, GB | 1 |
Corvalan, C | 1 |
Mericq, V | 1 |
Benko, F | 1 |
Chomová, M | 1 |
Uličná, O | 1 |
Ďuračka, M | 1 |
Kováč, J | 1 |
Tvrdá, E | 1 |
Davis, SR | 1 |
Bell, RJ | 1 |
Robinson, PJ | 1 |
Handelsman, DJ | 1 |
Gilbert, T | 1 |
Phung, J | 1 |
Desai, R | 1 |
Lockery, JE | 1 |
Woods, RL | 1 |
Wolfe, RS | 1 |
Reid, CM | 1 |
Nelson, MR | 1 |
Murray, AM | 1 |
McNeil, JJ | 1 |
Teixeira, CJ | 2 |
Veras, K | 2 |
de Oliveira Carvalho, CR | 2 |
Mezzullo, M | 1 |
Di Dalmazi, G | 1 |
Fazzini, A | 1 |
Baccini, M | 1 |
Repaci, A | 1 |
Gambineri, A | 2 |
Vicennati, V | 2 |
Pelusi, C | 1 |
Pagotto, U | 1 |
Fanelli, F | 1 |
Yokokawa, T | 1 |
Sato, K | 4 |
Narusawa, R | 1 |
Kido, K | 1 |
Mori, R | 1 |
Iwanaka, N | 1 |
Hayashi, T | 1 |
Hashimoto, T | 1 |
Ahmed, AA | 1 |
Moselhy, SS | 1 |
Kumosani, TA | 1 |
Huwait, EA | 1 |
Al-Ghamdi, MA | 1 |
Al-Madani, KA | 1 |
AlToukhi, MH | 1 |
Kumosani, AT | 1 |
Goddings, AL | 1 |
Viner, RM | 1 |
Mundy, L | 1 |
Romaniuk, H | 1 |
Molesworth, C | 1 |
Carlin, JB | 1 |
Allen, NB | 1 |
Patton, GC | 1 |
Miura, I | 1 |
Komine, S | 1 |
Okada, K | 1 |
Wada, S | 1 |
Warabi, E | 1 |
Uchida, F | 1 |
Oh, S | 1 |
Suzuki, H | 1 |
Mizokami, Y | 1 |
Shoda, J | 1 |
Maciejewski, A | 1 |
Litwinowicz, M | 1 |
Miechowicz, I | 1 |
Marcinkowska, E | 1 |
Florczak-Wyspiańska, J | 1 |
Jerominek, A | 1 |
Grzymisławski, M | 1 |
Łącka, K | 1 |
Wise-Oringer, BK | 1 |
Burghard, AC | 1 |
Park, H | 1 |
Auchus, RJ | 2 |
Oberfield, SE | 1 |
Uhlemann, AC | 1 |
Santos-Silva, R | 1 |
Fontoura, M | 1 |
Guimarães, JT | 1 |
Barros, H | 1 |
Santos, AC | 1 |
de Groot, CJ | 1 |
van den Berg, A | 1 |
Ballieux, BEPB | 1 |
Kroon, HM | 1 |
Rings, EHHM | 1 |
Wit, JM | 1 |
van den Akker, ELT | 1 |
Al Nofal, A | 1 |
Viers, LD | 1 |
Javed, A | 1 |
Ara, J | 1 |
Nuwormegbe, SA | 1 |
Sajo, MEJ | 1 |
Kim, SK | 1 |
Shim, KY | 1 |
Lee, KJ | 1 |
Maliqueo, M | 1 |
Cruz, G | 1 |
Espina, C | 1 |
Contreras, I | 1 |
García, M | 1 |
Echiburú, B | 1 |
Crisosto, N | 1 |
Stárka, L | 5 |
Ribeiro, LM | 1 |
da Cunha Araujo, LC | 1 |
Curi, R | 1 |
Blaslov, K | 1 |
Kruljac, I | 1 |
Mirošević, G | 1 |
Kirigin Biloš, LS | 1 |
Vrkljan, M | 1 |
Aoki, K | 1 |
Terauchi, Y | 1 |
Tatara, K | 1 |
Reading, CL | 2 |
Stickney, DR | 1 |
Flores-Riveros, J | 2 |
Destiche, DA | 1 |
Ahlem, CN | 2 |
Cefalu, WT | 1 |
Frincke, JM | 3 |
Máčová, L | 2 |
Bičíková, M | 3 |
Zamrazilová, H | 3 |
Hill, M | 3 |
Kazihnitková, H | 1 |
Sedláčková, B | 3 |
McNamara, KM | 1 |
Sasano, H | 1 |
Cecconello, AL | 1 |
Trapp, M | 1 |
Hoefel, AL | 1 |
Marques, CV | 1 |
Arbo, BD | 1 |
Osterkamp, G | 1 |
Kucharski, LC | 1 |
Ribeiro, MF | 1 |
Wei, D | 1 |
Zhang, Y | 1 |
Chen, F | 1 |
Yu, Q | 1 |
Horii, N | 1 |
Mesaki, N | 2 |
Iemitsu, M | 2 |
Goh, VH | 1 |
Hart, WG | 1 |
Sosvorová, L | 1 |
Vítků, J | 1 |
O'Reilly, MW | 1 |
Kempegowda, P | 1 |
Jenkinson, C | 1 |
Taylor, AE | 1 |
Quanson, JL | 1 |
Storbeck, KH | 1 |
Arlt, W | 1 |
Straub, RH | 1 |
Tankó, LB | 1 |
Christiansen, C | 1 |
Larsen, PJ | 1 |
Jessop, DS | 1 |
Ludwig, AK | 1 |
Goharian, LG | 1 |
Dietze, T | 1 |
Tauchert, S | 1 |
Rudolf, S | 1 |
Diedrich, K | 1 |
Schweiger, U | 1 |
Oltmanns, KM | 1 |
Binder, G | 1 |
Weber, S | 1 |
Ehrismann, M | 1 |
Zaiser, N | 1 |
Meisner, C | 1 |
Ranke, MB | 1 |
Maier, L | 1 |
Wudy, SA | 1 |
Hartmann, MF | 1 |
Heinrich, U | 1 |
Bettendorf, M | 1 |
Doerr, HG | 1 |
Pfaeffle, RW | 1 |
Keller, E | 1 |
Gupte, RS | 1 |
Floyd, BC | 1 |
Kozicky, M | 1 |
George, S | 1 |
Ungvari, ZI | 1 |
Neito, V | 1 |
Wolin, MS | 1 |
Gupte, SA | 1 |
Shayya, R | 1 |
Chang, RJ | 1 |
Lu, M | 1 |
Patsouris, D | 1 |
Li, P | 1 |
Watkins, S | 1 |
Schenk, S | 1 |
Olefsky, JM | 1 |
Labrie, F | 6 |
Hakkak, R | 1 |
Shaaf, S | 1 |
Jo, CH | 1 |
MacLeod, S | 1 |
Korourian, S | 1 |
Auci, DL | 1 |
Kennedy, MR | 1 |
Page, TM | 1 |
Baillot, A | 2 |
Vibarel-Rebot, N | 2 |
Thomasson, R | 1 |
Jollin, L | 1 |
Amiot, V | 2 |
Emy, P | 2 |
Collomp, K | 2 |
Tena, G | 1 |
Moran, C | 1 |
Romero, R | 1 |
Moran, S | 1 |
Aizawa, K | 1 |
Fujita, S | 1 |
Hannon, TS | 1 |
Arslanian, SA | 1 |
Koehler, E | 1 |
Swain, J | 1 |
Sanderson, S | 1 |
Krishnan, A | 1 |
Watt, K | 1 |
Charlton, M | 1 |
Miller, GD | 1 |
Nicklas, BJ | 1 |
Davis, CC | 1 |
Legault, C | 1 |
Messier, SP | 1 |
Dušátková, L | 1 |
Matucha, P | 1 |
Tan, RS | 1 |
Pu, SJ | 1 |
Corrigan, B | 1 |
L'Allemand, D | 1 |
Eiholzer, U | 1 |
Rousson, V | 1 |
Girard, J | 1 |
Blum, W | 1 |
Torresani, T | 1 |
Gasser, T | 1 |
Kajita, K | 1 |
Ishizuka, T | 1 |
Mune, T | 1 |
Miura, A | 1 |
Ishizawa, M | 1 |
Kanoh, Y | 1 |
Kawai, Y | 1 |
Natsume, Y | 1 |
Yasuda, K | 1 |
Lemieux, C | 1 |
Picard, F | 1 |
Richard, D | 1 |
Deshaies, Y | 1 |
SONKA, J | 14 |
GREGOROVA, I | 8 |
SLABOCHOVA, Z | 1 |
RATH, R | 3 |
GREGORVA, I | 1 |
PAV, J | 2 |
SKRHA, F | 1 |
DENEVE, L | 1 |
VERMEULEN, A | 4 |
KOREF, O | 1 |
FEHER, T | 7 |
HOLLO, I | 1 |
Monteleone, P | 3 |
Luisi, M | 2 |
De Filippis, G | 1 |
Colurcio, B | 1 |
Genazzani, AR | 3 |
Maj, M | 1 |
Charkaluk, ML | 1 |
Trivin, C | 1 |
Brauner, R | 1 |
Patel, BN | 1 |
Pang, D | 1 |
Stern, Y | 1 |
Silverman, W | 1 |
Kline, JK | 1 |
Mayeux, R | 1 |
Schupf, N | 1 |
Vrbíková, J | 1 |
Dvoráková, K | 1 |
Stanická, S | 1 |
Vondra, K | 1 |
Tchernof, A | 4 |
El-Khayat, HA | 1 |
Abd El-Basset, FZ | 1 |
Tomoum, HY | 1 |
Tohamy, SM | 1 |
Zaky, AA | 1 |
Mohamed, MS | 1 |
Hakky, SM | 1 |
El Barbary, NS | 1 |
Nassef, NM | 1 |
Ueshiba, H | 2 |
Miyachi, Y | 2 |
Villareal, DT | 1 |
Holloszy, JO | 3 |
Havelock, JC | 1 |
Rainey, WE | 1 |
Porter, J | 3 |
Van Vrancken, M | 1 |
Corll, C | 1 |
Thompson, H | 1 |
Svec, F | 19 |
Kapoor, D | 1 |
Malkin, CJ | 1 |
Channer, KS | 1 |
Jones, TH | 1 |
Zumoff, B | 1 |
Strain, GW | 1 |
Heymsfield, SB | 1 |
Lichtman, S | 1 |
Fu, JF | 1 |
Dong, GP | 1 |
Liang, L | 1 |
Jiang, YJ | 1 |
Chen, LQ | 1 |
Dayan, C | 1 |
Zhang, YF | 1 |
Yang, YS | 1 |
Hong, J | 1 |
Gu, WQ | 1 |
Shen, CF | 1 |
Xu, M | 1 |
Du, PF | 1 |
Li, XY | 1 |
Ning, G | 1 |
Park, J | 1 |
Choe, SS | 1 |
Choi, AH | 1 |
Kim, KH | 1 |
Yoon, MJ | 1 |
Suganami, T | 1 |
Ogawa, Y | 1 |
Kim, JB | 1 |
Słopień, R | 1 |
Lewandowski, K | 1 |
Kolacz, E | 1 |
Zawilska, K | 1 |
Warenik-Szymankiewicz, A | 1 |
de Heredia, FP | 1 |
Cerezo, D | 1 |
Zamora, S | 2 |
Garaulet, M | 2 |
Hernández-Morante, JJ | 1 |
Pérez-de-Heredia, F | 1 |
Luján, JA | 1 |
Pasquali, R | 2 |
Casimirri, F | 2 |
Venturoli, S | 1 |
Paradisi, R | 1 |
Mattioli, L | 1 |
Capelli, M | 1 |
Melchionda, N | 1 |
Labò, G | 1 |
Cleary, MP | 12 |
Billheimer, J | 1 |
Finan, A | 1 |
Sartin, JL | 2 |
Schwartz, AG | 4 |
Kent, S | 1 |
Hard, GC | 1 |
Pashko, LL | 2 |
Abou-Gharbia, M | 1 |
Swern, D | 1 |
Bodrogi, L | 3 |
Vallent, K | 1 |
Ribai, Z | 1 |
Laatikainen, T | 1 |
Tulenheimo, A | 1 |
Andersson, B | 1 |
Kärkkäinen, J | 1 |
Shepherd, A | 1 |
Jenks, B | 1 |
Pintor, C | 2 |
Loche, S | 1 |
Faedda, A | 1 |
Fanni, V | 1 |
Nurchi, AM | 1 |
Corda, R | 2 |
Siiteri, PK | 1 |
Lobo, RA | 1 |
March, CM | 1 |
Goebelsmann, U | 1 |
Mishell, DR | 1 |
Abrahamsson, L | 1 |
Hackl, H | 1 |
Hilton, CW | 1 |
Wright, B | 2 |
Browne, E | 1 |
Porter, JR | 14 |
Jakubowicz, DJ | 5 |
Beer, NA | 5 |
Beer, RM | 5 |
Nestler, JE | 7 |
Crave, JC | 1 |
Fimbel, S | 1 |
Lejeune, H | 1 |
Cugnardey, N | 1 |
Déchaud, H | 1 |
Pugeat, M | 1 |
Clark, DG | 1 |
Tomas, FM | 1 |
Withers, RT | 1 |
Brinkman, M | 1 |
Berry, MN | 1 |
Oliver, JR | 1 |
Owens, PC | 1 |
Butler, RN | 1 |
Ballard, FJ | 1 |
Nestel, PJ | 1 |
Wise, T | 1 |
Klindt, J | 1 |
Buonomo, FC | 1 |
Abadie, JM | 4 |
Correa, G | 2 |
Browne, ES | 4 |
Herranz, L | 1 |
Megia, A | 1 |
Grande, C | 1 |
González-Gancedo, P | 1 |
Pallardo, F | 1 |
Després, JP | 3 |
Bélanger, A | 3 |
Dupont, A | 1 |
Prud'homme, D | 2 |
Moorjani, S | 1 |
Lupien, PJ | 1 |
Sütterlin, M | 1 |
Steck, T | 1 |
De Pergola, G | 5 |
Triggiani, V | 1 |
Giorgino, F | 5 |
Cospite, MR | 3 |
Garruti, G | 3 |
Cignarelli, M | 4 |
Guastamacchia, E | 1 |
Giorgino, R | 5 |
Ebeling, P | 1 |
Koivisto, VA | 1 |
Holte, J | 1 |
Bergh, T | 1 |
Gennarelli, G | 1 |
Wide, L | 1 |
Field, AE | 1 |
Colditz, GA | 1 |
Willett, WC | 1 |
Longcope, C | 1 |
McKinlay, JB | 1 |
Geisthövel, F | 1 |
Olbrich, M | 1 |
Frorath, B | 1 |
Thiemann, M | 1 |
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Wright, BE | 4 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effect of Dehydroepiandrosterone on Live Birth Rate in Subfertile Patients With Poor Ovarian Responds[NCT02432248] | 350 participants (Anticipated) | Interventional | 2015-02-28 | Recruiting | |||
DHEA + Acolbifene Against Vasomotor Symptoms (Hot Flushes) in Postmenopausal Women (Placebo Controlled, Double Blind and Randomized Phase III Study to Evaluate the Effects of 12-Week Treatment With DHEA (Prasterone) and Acolbifene on Vasomotor Symptoms (H[NCT01452373] | Phase 3 | 238 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
Biologic Effects of DHEA in Humans[NCT00099697] | 56 participants | Interventional | 2001-06-30 | Completed | |||
Biological Effects of DHEA in the Elderly[NCT00111930] | 144 participants | Interventional | 2000-08-31 | Completed | |||
DHEA+Exercise-Effect on Sarcopenia and Osteopenia of Aging[NCT00205686] | Phase 3 | 64 participants | Interventional | 2001-04-30 | Completed | ||
Effect of DHEA on Skin Aging - Placebo-Controlled and Randomized Phase III Study in Postmenopausal Women.[NCT00248989] | Phase 3 | 150 participants (Actual) | Interventional | 2004-11-01 | Completed | ||
Diabetes and Cardiovascular Risk In Mexico City (San Antonio Heart Study)[NCT00005146] | 0 participants | Observational | 1979-05-31 | Completed | |||
Is DHEA Replacement Beneficial?[NCT00182975] | Phase 3 | 142 participants (Actual) | Interventional | 2002-09-30 | Completed | ||
BNP Pharmacodynamics and Effects on Metabolism in Lean and Obese Subjects[NCT01977859] | Phase 1 | 4 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
Effect of Nesiritide Infusion on Insulin Sensitivity in Healthy Obese Insulin Resistant Subjects[NCT03234751] | Phase 1 | 6 participants (Actual) | Interventional | 2017-07-13 | Completed | ||
Predicting Adaptive Thermogenesis[NCT00687115] | Phase 2 | 83 participants (Actual) | Interventional | 2008-09-18 | Completed | ||
The Effects of Testosterone and Nutritional Supplementation, Alone and Combined, on the Adverse Effects of Under-Nutrition in the Elderly[NCT00117000] | Phase 3 | 200 participants | Interventional | 2003-07-31 | Active, not recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
38 reviews available for dehydroepiandrosterone and Obesity
Article | Year |
---|---|
Dehydroepiandrosterone on metabolism and the cardiovascular system in the postmenopausal period.
Topics: Aged; Aged, 80 and over; Aging; Animals; Cardiovascular Diseases; Cardiovascular System; Dehydroepia | 2020 |
The origin of 7alpha-hydroxy-dehydroepiandrosterone and its physiological role: a history of discoveries.
Topics: Animals; Brain; Dehydroepiandrosterone; Humans; Hydrocortisone; Mental Disorders; Nervous System Dis | 2017 |
Effect of Dehydroepiandrosterone (DHEA) on Diabetes Mellitus and Obesity.
Topics: Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes Mellitus, Type 2; Humans; | 2018 |
The intracrinology of breast cancer.
Topics: Androgens; Aromatase; Breast; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfa | 2015 |
Reproductive endocrinology of adolescent polycystic ovary syndrome.
Topics: Adolescent; Adult; Androgens; Anovulation; Anti-Mullerian Hormone; Child; Dehydroepiandrosterone; Fe | 2010 |
Impact of obesity on hypogonadism in the andropause.
Topics: Aged; Aging; Body Composition; Climacteric; Dehydroepiandrosterone; Diabetes Mellitus; Humans; Hypog | 2002 |
DHEA and sport.
Topics: Adjuvants, Immunologic; Aging; Cardiovascular Diseases; Dehydroepiandrosterone; Exercise; Female; Hu | 2002 |
[DEHYDROEPIANDROSTERONE--A NEW APPROACH TO THE PATHOGENESIS OF OBESITY].
Topics: Dehydroepiandrosterone; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; Humans; Insulin; Lipid Me | 1963 |
Dehydroepiandrosterone, obesity and cardiovascular disease risk: a review of human studies.
Topics: Cardiovascular Diseases; Dehydroepiandrosterone; Humans; Obesity; Risk Factors | 2004 |
The rise in adrenal androgen biosynthesis: adrenarche.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Child; Dehydroepiandrosterone; Dehydroepiand | 2004 |
Androgens, insulin resistance and vascular disease in men.
Topics: Aged; Aging; Arteriosclerosis; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Humans; Insulin Re | 2005 |
Extraglandular oestrogen formation and serum binding of oestradiol: relationship to cancer.
Topics: Adipose Tissue; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrogens; Fem | 1981 |
Physiological importance of dehydroepiandrosterone.
Topics: Breast Neoplasms; Cardiovascular Diseases; Dehydroepiandrosterone; Female; Humans; Insulin Resistanc | 1994 |
[Adrenal androgens: traditionally forgotten hormones. Today, of current importance].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Cardiovascular Diseases; Dehydroepiandroster | 1993 |
Is dehydroepiandrosterone an antiobesity agent?
Topics: Animals; Dehydroepiandrosterone; Humans; Obesity | 1993 |
Dehydroepiandrosterone and body fat.
Topics: Adipose Tissue; Animals; Dehydroepiandrosterone; Humans; Insulin; Metabolism; Obesity | 1995 |
Dehydroepiandrosterone (DHEA) for diabetic patients?
Topics: Dehydroepiandrosterone; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Insulin; Obesity | 1996 |
Perimenopausal obesity.
Topics: Dehydroepiandrosterone; Estrogen Replacement Therapy; Female; Gonadal Steroid Hormones; Humans; Neur | 1996 |
Decreased androgen levels and obesity in men.
Topics: Dehydroepiandrosterone; Humans; Hypogonadism; Leydig Cells; Male; Obesity; Sex Hormone-Binding Globu | 1996 |
Obesity and metabolic complications: contribution of dehydroepiandrosterone and other steroid hormones.
Topics: Adipose Tissue; Cardiovascular Diseases; Dehydroepiandrosterone; Female; Gonadal Steroid Hormones; H | 1996 |
DHEA: science or wishful thinking?
Topics: Adult; Aged; Aging; Dehydroepiandrosterone; Female; Humans; Male; Middle Aged; Obesity; Osteoporosis | 1998 |
Calorie restriction in primates: will it work and how will we know?
Topics: Aging; Analysis of Variance; Animals; Biomarkers; Body Weight; Cardiovascular Diseases; Cause of Dea | 1999 |
Dietary supplements of dehydroepiandrosterone in relation to breast cancer risk.
Topics: Animals; Breast Neoplasms; Dehydroepiandrosterone; Dietary Supplements; Female; Humans; Insulin-Like | 1999 |
The effects of dehydroepiandrosterone on carcinogenesis, obesity, the immune system, and aging.
Topics: Aging; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Glucosephosphate Dehydrogena | 2000 |
The biology of aging.
Topics: Aged; Aging; Animals; Dehydroepiandrosterone; Diet, Fat-Restricted; Energy Intake; Exercise; Female; | 2000 |
[Testosterone and dehydroepiandrosterone deficiency, general adiposity and visceral obesity during normal male aging].
Topics: Adipose Tissue; Aging; Body Mass Index; Dehydroepiandrosterone; Humans; Male; Middle Aged; Obesity; | 2001 |
[Dehydroepiandrosterone (DHEA)--youth hormone?].
Topics: Aging; Arteriosclerosis; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes | 2001 |
[Hyperuricemia and arteriosclerosis].
Topics: Adult; Arteriosclerosis; Coronary Disease; Dehydroepiandrosterone; Female; Gout; Humans; Hyperlipide | 1978 |
Diabetes and adrenal disease.
Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Animals; Cushing Syndrome; Dehydroepiandrosterone; | 1992 |
The antiobesity effect of dehydroepiandrosterone in rats.
Topics: Adipose Tissue; Animals; Body Weight; Dehydroepiandrosterone; Lipids; Liver; Male; Mice; Mice, Obese | 1991 |
Obesity in the dog: role of the adrenal steroid dehydroepiandrosterone (DHEA).
Topics: Animals; Cholesterol; Dehydroepiandrosterone; Dog Diseases; Dogs; Obesity; Weight Loss | 1991 |
Early responses of female obese rats to dehydroepiandrosterone treatment.
Topics: Animals; Dehydroepiandrosterone; Female; Obesity; Rats; Rats, Zucker; Sex Characteristics | 1991 |
Hormonal intervention: "buffer hormones" or "state dependency". The role of dehydroepiandrosterone (DHEA), thyroid hormone, estrogen and hypophysectomy in aging.
Topics: Aging; Animals; Cell Transformation, Neoplastic; Dehydroepiandrosterone; Diabetes Mellitus; Estrogen | 1988 |
Control of secretion and the function of C19-delta 5-steroids of the human adrenal gland.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; | 1985 |
The adrenal cortex and virilization.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyper | 1985 |
Inhibition of tumor development by dehydroepiandrosterone and related steroids.
Topics: Animals; Dehydroepiandrosterone; Energy Intake; Glucosephosphate Dehydrogenase; Mice; Neoplasms, Exp | 1986 |
[Dehydroepiandrosterone deficiency --a new syndrome?].
Topics: Deficiency Diseases; Dehydroepiandrosterone; Female; Humans; In Vitro Techniques; Male; Middle Aged; | 1965 |
Metabolic aspects of obesity.
Topics: Acidosis; Adenosine Triphosphate; Adipose Tissue; Adrenal Cortex Hormones; Alcoholism; Animals; Body | 1970 |
20 trials available for dehydroepiandrosterone and Obesity
Article | Year |
---|---|
Determinants of Advanced Bone Age in Childhood Obesity
.
Topics: Adolescent; Androgens; Bone Density; Child; Dehydroepiandrosterone; Estrogens; Female; Humans; Male; | 2017 |
A synthetic anti-inflammatory sterol improves insulin sensitivity in insulin-resistant obese impaired glucose tolerance subjects.
Topics: Adiponectin; Adult; Anti-Inflammatory Agents; Blood Glucose; Body Mass Index; C-Reactive Protein; Ch | 2013 |
Effects of dehydroepiandrosterone therapy on pubic hair growth and psychological well-being in adolescent girls and young women with central adrenal insufficiency: a double-blind, randomized, placebo-controlled phase III trial.
Topics: Adolescent; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Blood Pressure; Brain Neoplas | 2009 |
A new antidiabetic compound attenuates inflammation and insulin resistance in Zucker diabetic fatty rats.
Topics: Adult; Analysis of Variance; Animals; Blood Glucose; Blotting, Western; Cell Movement; Chemokines; C | 2010 |
Basal growth hormone concentration increased following a weight loss focused dietary intervention in older overweight and obese women.
Topics: Aged; Aging; Dehydroepiandrosterone; Female; Human Growth Hormone; Humans; Hydrocortisone; Male; Nut | 2012 |
Increased adrenal androgen levels in patients with Prader-Willi syndrome are associated with insulin, IGF-I, and leptin, but not with measures of obesity.
Topics: Adolescent; Adrenal Glands; Analysis of Variance; Androgens; Androstenedione; Anthropometry; Body Co | 2002 |
Effects of the long-acting calcium channel blockers, amlodipine, manidipine and cilnidipine on steroid hormones and insulin resistance in hypertensive obese patients.
Topics: Aged; Amlodipine; Analysis of Variance; Body Mass Index; Calcium Channel Blockers; Dehydroepiandrost | 2004 |
Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial.
Topics: Abdomen; Adipose Tissue; Aged; Blood Glucose; Dehydroepiandrosterone; Double-Blind Method; Female; G | 2004 |
Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial.
Topics: Abdomen; Adipose Tissue; Aged; Blood Glucose; Dehydroepiandrosterone; Double-Blind Method; Female; G | 2004 |
Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial.
Topics: Abdomen; Adipose Tissue; Aged; Blood Glucose; Dehydroepiandrosterone; Double-Blind Method; Female; G | 2004 |
Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial.
Topics: Abdomen; Adipose Tissue; Aged; Blood Glucose; Dehydroepiandrosterone; Double-Blind Method; Female; G | 2004 |
Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial.
Topics: Abdomen; Adipose Tissue; Aged; Blood Glucose; Dehydroepiandrosterone; Double-Blind Method; Female; G | 2004 |
Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial.
Topics: Abdomen; Adipose Tissue; Aged; Blood Glucose; Dehydroepiandrosterone; Double-Blind Method; Female; G | 2004 |
Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial.
Topics: Abdomen; Adipose Tissue; Aged; Blood Glucose; Dehydroepiandrosterone; Double-Blind Method; Female; G | 2004 |
Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial.
Topics: Abdomen; Adipose Tissue; Aged; Blood Glucose; Dehydroepiandrosterone; Double-Blind Method; Female; G | 2004 |
Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial.
Topics: Abdomen; Adipose Tissue; Aged; Blood Glucose; Dehydroepiandrosterone; Double-Blind Method; Female; G | 2004 |
A randomized double-blind crossover study of the antiobesity effects of etiocholanedione.
Topics: Adult; Aged; Anti-Obesity Agents; Body Composition; Body Weight; Cross-Over Studies; Dehydroepiandro | 1994 |
Effects of diet and metformin administration on sex hormone-binding globulin, androgens, and insulin in hirsute and obese women.
Topics: Androgens; Apolipoprotein A-I; Apolipoproteins B; Blood Glucose; Body Composition; Cholesterol; Chol | 1995 |
Differences in substrate metabolism between self-perceived 'large-eating' and 'small-eating' women.
Topics: Adult; Appetite; Basal Metabolism; Calorimetry, Indirect; Carbon Dioxide; Dehydroepiandrosterone; De | 1995 |
Sensitivity of plasma insulin levels in obese and non-obese women with functional hyperandrogenism.
Topics: Adult; Androstenedione; Body Mass Index; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Fem | 1995 |
The relation of smoking, age, relative weight, and dietary intake to serum adrenal steroids, sex hormones, and sex hormone-binding globulin in middle-aged men.
Topics: Adrenal Glands; Adult; Aged; Aging; Body Mass Index; Body Weight; Cross-Sectional Studies; Dehydroep | 1994 |
Effects of nitrendipine on glucose tolerance and serum insulin and dehydroepiandrosterone sulfate levels in insulin-resistant obese and hypertensive men.
Topics: Adult; Analysis of Variance; Blood Glucose; Blood Pressure; Dehydroepiandrosterone; Dehydroepiandros | 1993 |
The calcium channel blocker amlodipine raises serum dehydroepiandrosterone sulfate and androstenedione, but lowers serum cortisol, in insulin-resistant obese and hypertensive men.
Topics: Adult; Amlodipine; Androgens; Androstenedione; Calcium Channel Blockers; Dehydroepiandrosterone; Deh | 1993 |
The acute effect of a noontime meal on the serum levels of cortisol and DHEA in lean and obese women.
Topics: Adolescent; Adult; Body Mass Index; Dehydroepiandrosterone; Female; Food; Humans; Hydrocortisone; Mi | 1997 |
The effect of dehydroepiandrosterone combined with a low-fat diet in spontaneously obese dogs: a clinical trial.
Topics: Animals; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dehydroepiandrosterone; Diet, Fat-Restrict | 1998 |
Metformin therapy improves the menstrual pattern with minimal endocrine and metabolic effects in women with polycystic ovary syndrome.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Androstenedione; Blood Glucose; Cohort Studies; Dehydroepiandro | 1998 |
Six-month oral dehydroepiandrosterone supplementation in early and late postmenopause.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Aged; Androgens; beta-Endorphin; Body Mass Index; | 2000 |
The effects of oral dehydroepiandrosterone on endocrine-metabolic parameters in postmenopausal women.
Topics: Administration, Oral; Adrenal Glands; Aged; Aging; Androgens; Body Weight; Dehydroepiandrosterone; D | 1990 |
200 other studies available for dehydroepiandrosterone and Obesity
Article | Year |
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High DHEAS in girls and metabolic features throughout pubertal maturation.
Topics: Adolescent; Adrenarche; Body Mass Index; Child; Cohort Studies; Dehydroepiandrosterone; Dehydroepian | 2022 |
The impact of diabetes mellitus type 2 on the steroidogenesis of male Zucker Diabetic Fatty rats.
Topics: Animals; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Estradiol; Follicle Stimulating Hormone; | 2022 |
Testosterone and Estrone Increase From the Age of 70 Years: Findings From the Sex Hormones in Older Women Study.
Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Community-Based Participatory Research; Cross-Sectional | 2019 |
Impact of age, body weight and metabolic risk factors on steroid reference intervals in men.
Topics: 17-alpha-Hydroxyprogesterone; Age Factors; Androstenedione; Body Mass Index; Body Weight; Chromatogr | 2020 |
Dehydroepiandrosterone activates 5'-adenosine monophosphate-activated protein kinase and suppresses lipid accumulation and adipocyte differentiation in 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; AMP-Activated Protein Kinases; Animals; Cell Differentiation | 2020 |
Ultrasonographic and biochemical assessments as early prediction of polycystic ovarian syndrome in obese women.
Topics: Adult; Anovulation; Body Mass Index; Case-Control Studies; Dehydroepiandrosterone; Female; Follicle | 2020 |
Growth and adrenarche: findings from the CATS observational study.
Topics: Adrenarche; Biomarkers; Body Height; Body Mass Index; Body Size; Body Weight; Child; Child Developme | 2021 |
Prevention of non-alcoholic steatohepatitis by long-term exercise via the induction of phenotypic changes in Kupffer cells of hyperphagic obese mice.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cells, Cultured; Dehydroepiandrost | 2021 |
Is there an association of cortisol, DHEA-S and cortisol/DHEA-S ratio with obesity and selected metabolic parameters?
Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hydrocortisone; Obesity | 2021 |
Salivary microbiome differences in prepubertal children with and without adrenal androgen excess.
Topics: Androgens; Child; Cross-Sectional Studies; Dehydroepiandrosterone; Humans; Microbiota; Obesity; Over | 2022 |
Association of dehydroepiandrosterone sulfate, birth size, adiposity and cardiometabolic risk factors in 7-year-old children.
Topics: Adiposity; Body Mass Index; C-Reactive Protein; Cardiometabolic Risk Factors; Child; Dehydroepiandro | 2022 |
Can the source of hyperandrogenism in adolescents with polycystic ovary syndrome predict metabolic phenotype?
Topics: Adolescent; Adrenal Glands; Cohort Studies; Dehydroepiandrosterone; Female; Humans; Hyperandrogenism | 2017 |
Potential therapeutic effect of alkaline reduced water in polycystic ovarian syndrome.
Topics: Animals; Dehydroepiandrosterone; Female; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydr | 2017 |
Obesity during pregnancy affects sex steroid concentrations depending on fetal gender.
Topics: Adaptation, Physiological; Adult; Aromatase; Blotting, Western; Body Mass Index; Dehydroepiandroster | 2017 |
Dehydroepiandrosterone supplementation is not beneficial in the late postmenopausal period in diet-induced obese rats.
Topics: Adiposity; Animals; Dehydroepiandrosterone; Diet, High-Fat; Dietary Supplements; Eating; Female; Glu | 2018 |
The possible role of stress induced hormonal disbalance in the patophysiology of insulin resistane in lean individuals.
Topics: Adiposity; alpha 1-Antitrypsin; Blood Glucose; Body Weight; Cardiovascular Diseases; Dehydroepiandro | 2018 |
Aerobic exercise training and dehydroepiandrosterone administration increase testicular sex steroid hormones and enhance reproductive function in high-sucrose-induced obese rats.
Topics: Animals; Dehydroepiandrosterone; Gonadal Steroid Hormones; Male; Obesity; Physical Conditioning, Ani | 2019 |
Reduced levels of circulating 7alpha-hydroxy-dehydroepiandrosterone in treated adolescent obese patients.
Topics: Adolescent; Biomarkers; Body Mass Index; Caloric Restriction; Dehydroepiandrosterone; Female; Humans | 2014 |
Sex-related differences in the effects of high-fat diets on DHEA-treated rats.
Topics: Animals; Blood Glucose; Body Weight; Dehydroepiandrosterone; Diet, High-Fat; Female; Hyperinsulinism | 2015 |
[Impact of androgen level on body adipose tissue content and distribution in middle life women].
Topics: Absorptiometry, Photon; Adipose Tissue; Adult; Body Fat Distribution; Cross-Sectional Studies; Dehyd | 2015 |
DHEA Administration Activates Transcription of Muscular Lipid Metabolic Enzymes via PPARα and PPARδ in Obese Rats.
Topics: Adiponectin; Animals; Dehydroepiandrosterone; Gene Expression Regulation; Lipid Metabolism; Male; Mu | 2016 |
Association of general and abdominal obesity with age, endocrine and metabolic factors in Asian men.
Topics: Adult; Age Factors; Aged; Asian People; Blood Glucose; China; Dehydroepiandrosterone; Estradiol; Hum | 2016 |
Steroid hormones related to 11beta-hydroxysteroid dehydrogenase type 1 in treated obesity.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adolescent; Biomarkers; Cohort Studies; Dehydroepiandro | 2015 |
11-Oxygenated C19 Steroids Are the Predominant Androgens in Polycystic Ovary Syndrome.
Topics: Adult; Androgens; Androstenedione; Androstenes; Blood Glucose; Case-Control Studies; Chromatography, | 2017 |
Higher physical activity is associated with increased androgens, low interleukin 6 and less aortic calcification in peripheral obese elderly women.
Topics: 17-alpha-Hydroxyprogesterone; Absorptiometry, Photon; Aged; Aged, 80 and over; Androstenedione; Aort | 2008 |
Impact of glycemic variations on the regulation of androgen metabolism in obese women with polycystic ovary syndrome.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Androgens; Androstenedione; Blood Glucose; C-Peptide; Dehydroep | 2009 |
Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver.
Topics: 6-Aminonicotinamide; Animals; Cell Extracts; Cells, Cultured; Dehydroepiandrosterone; Diabetes Melli | 2009 |
DHEA, important source of sex steroids in men and even more in women.
Topics: Adrenal Glands; Age Factors; Aging; Anticarcinogenic Agents; Brain; Breast; Cardiovascular Diseases; | 2010 |
Dehydroepiandrosterone intake protects against 7,12-dimethylbenz(a)anthracene-induced mammary tumor development in the obese Zucker rat model.
Topics: Aging; Animals; Benz(a)Anthracenes; Body Weight; Carcinogens; Carcinoma, Ductal, Breast; Cytoprotect | 2010 |
A potential role for 5-androstene-3β,7β,17β-triol in obesity and metabolic syndrome.
Topics: Adult; Aged; Aged, 80 and over; Androstenols; Anti-Inflammatory Agents; Anti-Obesity Agents; Body Ma | 2011 |
Serum and saliva adrenocortical hormones in obese diabetic men during submaximal exercise.
Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes Mellitus; Exercise; Humans; Hydroco | 2011 |
Ovarian morphology and endocrine function in polycystic ovary syndrome.
Topics: Adult; Anthropometry; Body Mass Index; Case-Control Studies; Cross-Sectional Studies; Dehydroepiandr | 2011 |
Increased muscular dehydroepiandrosterone levels are associated with improved hyperglycemia in obese rats.
Topics: Animals; Blood Glucose; Body Weight; Cholestenone 5 alpha-Reductase; Dehydroepiandrosterone; Dietary | 2011 |
Differences in stimulated androgen levels in black and white obese adolescent females.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Androgens; Androstenedione; | 2012 |
Growth hormone, dehydroepiandrosterone and adiponectin levels in non-alcoholic steatohepatitis: an endocrine signature for advanced fibrosis in obese patients.
Topics: Adiponectin; Biomarkers; Dehydroepiandrosterone; Fatty Liver; Female; Growth Hormone; Humans; Liver | 2012 |
Effects of an 8-week aerobic exercise training on saliva steroid hormones, physical capacity, and quality of life in diabetic obese men.
Topics: Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Exercise; Humans; Hydrocortisone; Male; Middle Ag | 2012 |
7-oxygenated derivatives of dehydroepiandrosterone and obesity.
Topics: Adolescent; Body Size; Dehydroepiandrosterone; Female; Humans; Male; Obesity | 2012 |
Dehydroepiandrosterone down-regulates the expression of peroxisome proliferator-activated receptor gamma in adipocytes.
Topics: Adipocytes; Animals; Carrier Proteins; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding | 2003 |
The estrogen antagonist EM-652 and dehydroepiandrosterone prevent diet- and ovariectomy-induced obesity.
Topics: Adipose Tissue; Animals; Body Composition; Body Weight; Cholesterol; Dehydroepiandrosterone; Diet; D | 2003 |
[A CONTRIBUTION TO THE PATHOPHYSIOLOGY OF DEHYDROEPIANDROSTERONE IN OBESITY].
Topics: 17-Ketosteroids; Blood Chemical Analysis; Carbohydrate Metabolism; Dehydroepiandrosterone; Diet; Die | 1963 |
DEHYDROEPIANDROSTERONE IN OBESE DIABETICS.
Topics: Dehydroepiandrosterone; Diabetes Mellitus; Geriatrics; Humans; Lipid Metabolism; Obesity; Urine | 1964 |
DEHYDROEPIANDROSTERONE IN OBESE DIABETICS AFTER CORTICOTROPHIN STIMULATION.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Dehydroepiandrosterone; Diabetes Mellitus; Fluids and | 1965 |
THE DETERMINATION OF 17-OXOSTEROID SULPHATES IN HUMAN PLASMA.
Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenalectomy; Androsterone; Blood Chemical Analysis; | 1965 |
[CHANGES IN THE EXCRETION OF DEHYDROEPIANDROSTERONE UNDER ACTH-LOADING IN OBESITY. (PRELIMINARY REPORT)].
Topics: Adrenocorticotropic Hormone; Androsterone; Body Fluids; Dehydroepiandrosterone; Humans; Obesity; Uri | 1965 |
Circulating levels of neuroactive steroids in patients with binge eating disorder: a comparison with nonobese healthy controls and non-binge eating obese subjects.
Topics: Adult; Bulimia; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female | 2003 |
Premature pubarche as an indicator of how body weight influences the onset of adrenarche.
Topics: Adrenal Hyperplasia, Congenital; Birth Weight; Body Weight; Child; Child, Preschool; Dehydroepiandro | 2004 |
Obesity enhances verbal memory in postmenopausal women with Down syndrome.
Topics: Adult; Body Mass Index; Case-Control Studies; Dehydroepiandrosterone; Depression; Down Syndrome; Est | 2004 |
Flutamide suppresses adrenal steroidogenesis but has no effect on insulin resistance and secretion and lipid levels in overweight women with polycystic ovary syndrome.
Topics: 17-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androgen Antag | 2004 |
Physical growth and endocrinal disorders during pubertal maturation in girls with epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Dehydroepiandrosterone; Epilepsy; Female; Growth; | 2004 |
DHEA makes the fat go away. A recent study showed that the hormone could control the effects of obesity. But it's early. Don't be swayed by the promises in ads.
Topics: Abdominal Wall; Aged; Anti-Obesity Agents; Dehydroepiandrosterone; Humans; Obesity | 2005 |
The influence of dehydroepiandrosterone and 8-OH-DPAT on the caloric intake and hypothalamic neurotransmitters of lean and obese Zucker rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dehydroepiandrosterone; Diet; Dose-Response Relatio | 2005 |
Early activation of the inhibin B/FSH axis in obese Tanner stage G1PH1 boys.
Topics: Case-Control Studies; Child; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Follicle Stimul | 2006 |
Elevated serum levels of interleukin-18 are associated with insulin resistance in women with polycystic ovary syndrome.
Topics: Blood Glucose; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Dehydroepiandrosterone; Diabetes | 2006 |
Increase in glucose-6-phosphate dehydrogenase in adipocytes stimulates oxidative stress and inflammatory signals.
Topics: 3T3 Cells; Adipocytes; Adipose Tissue; Animals; Dehydroepiandrosterone; Gene Expression Regulation; | 2006 |
Comparison of fibrinolytic and metabolic system parameters in obese patients with polycystic ovary syndrome and women with simple obesity.
Topics: Adult; Blood Glucose; Case-Control Studies; Cholesterol; Dehydroepiandrosterone; Estradiol; Female; | 2006 |
Effect of dehydroepiandrosterone on protein and fat digestibility, body protein and muscular composition in high-fat-diet-fed old rats.
Topics: Adipocytes; Animals; Anti-Obesity Agents; Body Composition; Body Weight; Dehydroepiandrosterone; Die | 2007 |
Role of DHEA-S on body fat distribution: gender- and depot-specific stimulation of adipose tissue lipolysis.
Topics: Abdominal Fat; Adipose Tissue; Body Fat Distribution; Dehydroepiandrosterone; Dehydroepiandrosterone | 2008 |
Insulin resistance in patients with polycystic ovaries: its relationship to body weight and androgen levels.
Topics: Adult; Androstenedione; Blood Glucose; C-Peptide; Dehydroepiandrosterone; Dehydroepiandrosterone Sul | 1983 |
Metabolic consequences of dehydroepiandrosterone in lean and obese adult Zucker rats.
Topics: Animals; Body Weight; Dehydroepiandrosterone; Female; Glucosephosphate Dehydrogenase; Liver; Obesity | 1984 |
DHEA: "miracle" drug?
Topics: Adrenal Glands; Adult; Aged; Aging; Animals; Breast Neoplasms; Colonic Neoplasms; Dehydroepiandroste | 1982 |
Dehydroepiandrosterone: an anti-obesity and anti-carcinogenic agent.
Topics: Animals; Body Weight; Crosses, Genetic; Dehydroepiandrosterone; Female; Male; Mammary Neoplasms, Exp | 1981 |
Effect of food restriction, dehydroepiandrosterone, or obesity on the binding of 3H-7,12-dimethylbenz(a)anthracene to mouse skin DNA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Benz(a)Anthracenes; Dehydroepiandrosterone; DNA; F | 1983 |
A comparative study of steroid concentrations in human adipose tissue and the peripheral circulation.
Topics: Adipose Tissue; Adolescent; Adult; Aged; Androstenedione; Dehydroepiandrosterone; Estrogens; Female; | 1982 |
Role of human adipose tissue in the production and metabolism of steroid hormones.
Topics: 17-alpha-Hydroxyprogesterone; Adipose Tissue; Androstenedione; Breast Neoplasms; Dehydroepiandroster | 1982 |
Obesity, serum steroid levels, and pulsatile gonadotropin secretion in polycystic ovarian disease.
Topics: Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Estrone; | 1983 |
Effect of dehydroepiandrosterone on growth in lean and obese Zucker rats.
Topics: Adipose Tissue; Animals; Body Composition; Body Weight; Dehydroepiandrosterone; Feeding Behavior; Fe | 1984 |
Adrenal androgens in obese boys before and after weight loss.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Androgens; Androstenedione; Body Weight; Child; Dehydr | 1984 |
The modulating role of obesity and 17 beta-estradiol (E2) on bound and unbound E2 and adrenal androgens in oophorectomized women.
Topics: Adult; Androgens; Androstenediol; Androstenedione; Castration; Dehydroepiandrosterone; Dehydroepiand | 1982 |
Catabolic effects and the influence on hormonal variables under treatment with Gynodian-Depot or dehydroepiandrosterone (DHEA) oenanthate.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Androgens; Climacteric; Dehydroepiandrosterone; D | 1981 |
The effect of DHEA given chronically to Zucker rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Blood Glucose; Corticosterone; Dehydroepiandro | 1995 |
Disparate effects of weight reduction by diet on serum dehydroepiandrosterone-sulfate levels in obese men and women.
Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diet, Reducing; Female; Humans; Male; | 1995 |
Obesity and dehydroepiandrosterone/dehydroepiandrosterone sulfate relationships in lean, obese, and meat-type cross-bred boars: responses to porcine growth hormone.
Topics: Animal Husbandry; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Growth Hormone; I | 1995 |
Effect of dehydroepiandrosterone on neurotransmitter levels and appetite regulation of the obese Zucker rat. The Obesity Research Program.
Topics: Androgens; Animals; Appetite; Body Weight; Brain; Dehydroepiandrosterone; Dose-Response Relationship | 1993 |
Dehydroepiandrosterone sulphate, body fat distribution and insulin in obese men.
Topics: Adipose Tissue; Adolescent; Adult; Anthropometry; Body Composition; Body Constitution; Body Mass Ind | 1995 |
Reduced testosterone and adrenal C19 steroid levels in obese men.
Topics: Adipose Tissue; Adult; Androgens; Androstenediol; Androstenedione; Body Mass Index; Dehydroepiandros | 1995 |
The free testosterone to dehydroepiandrosterone sulphate molar ratio as a marker of visceral fat accumulation in premenopausal obese women.
Topics: Adipose Tissue; Adolescent; Adult; Anthropometry; Blood Glucose; Body Composition; Body Constitution | 1994 |
The independent effects of polycystic ovary syndrome and obesity on serum concentrations of gonadotrophins and sex steroids in premenopausal women.
Topics: Adult; Androstenedione; Body Composition; Body Mass Index; Cross-Sectional Studies; Dehydroepiandros | 1994 |
Disparate effects of insulin reduction with diltiazem on serum dehydroepiandrosterone sulfate levels in obese hypertensive men and women.
Topics: Adult; Blood Glucose; Blood Pressure; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diltia | 1994 |
Obesity and hypertestosteronaemia are independently and synergistically associated with elevated insulin concentrations and dyslipidaemia in pre-menopausal women.
Topics: Adult; Body Mass Index; Coronary Disease; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Fe | 1994 |
Sex hormones, body fat distribution, resting metabolic rate and glucose-induced thermogenesis in premenopausal obese women.
Topics: Adipose Tissue; Adult; Body Composition; Body Mass Index; Body Temperature Regulation; Dehydroepiand | 1994 |
Dehydroepiandrosterone regulation of the hepatic glucocorticoid receptor in the Zucker rat. The obesity research program.
Topics: Animals; Binding, Competitive; Dehydroepiandrosterone; Female; Liver; Obesity; Rats; Rats, Zucker; R | 1993 |
Insulin, C-peptide, androgens, and beta-endorphin response to oral glucose in patients with polycystic ovary syndrome.
Topics: Administration, Oral; Adult; Androgens; Androstenedione; beta-Endorphin; C-Peptide; Dehydroepiandros | 1994 |
Effects of a reduction in circulating insulin by metformin on serum dehydroepiandrosterone sulfate in nondiabetic men.
Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hypertension; Insulin; Lipids | 1994 |
Serum androgens and psychopathology in hirsute women.
Topics: Acne Vulgaris; Adolescent; Adult; Androgens; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; | 1993 |
Does taste aversion play a role in the effect of dehydroepiandrosterone in Zucker rats?
Topics: Administration, Oral; Animals; Avoidance Learning; Dehydroepiandrosterone; Diet; Eating; Female; Foo | 1994 |
Enhanced adrenocortical activity as a contributing factor to diabetes in hyperandrogenic women.
Topics: Adrenal Cortex; Adult; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Female; Glucose Tolerance | 1994 |
Visceral fat accumulation in relation to sex hormones in obese men and women undergoing weight loss therapy.
Topics: Adipose Tissue; Adult; Androstenedione; Body Composition; Dehydroepiandrosterone; Dehydroepiandroste | 1994 |
Obesity, body fat distribution and sex hormones in men.
Topics: Adipose Tissue; Adult; Alcohol Drinking; Anthropometry; Body Constitution; Cohort Studies; Dehydroep | 1993 |
24-hour serum cortisol profiles in women with polycystic ovary syndrome.
Topics: Adult; Androstenedione; Body Mass Index; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrost | 1993 |
Serum androgens in hyperinsulinemic Pima Indian and obese Caucasian women and their response to short-term insulin infusion.
Topics: Adipose Tissue; Adult; Arizona; Body Mass Index; Dehydroepiandrosterone; Dehydroepiandrosterone Sulf | 1993 |
Androsterone sulfate: physiology and clinical significance in hirsute women.
Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Adult; Androstenedione; Androsterone; Bio | 1993 |
Insulin-like growth factor-1 (IGF-1) and dehydroepiandrosterone sulphate in obese women.
Topics: Adult; Androstane-3,17-diol; Body Constitution; Body Mass Index; Dehydroepiandrosterone; Dehydroepia | 1993 |
A prospective study of dehydroepiandrosterone sulfate (DHEAS) and bone mineral density in older men and women.
Topics: Absorptiometry, Photon; Age Factors; Aged; Antihypertensive Agents; Bone Density; California; Dehydr | 1993 |
Race-dependent health risks of upper body obesity.
Topics: Adipose Tissue; Adult; Analysis of Variance; Anthropometry; Black People; Blood Glucose; Blood Press | 1993 |
The effect of discontinuing dehydroepiandrosterone supplementation on Zucker rat food intake and hypothalamic neurotransmitters.
Topics: Androstenedione; Animals; Body Weight; Dehydroepiandrosterone; Disease Models, Animal; Dopamine; Eat | 1995 |
The impact of obesity on hormonal parameters in hirsute and nonhirsute women.
Topics: Adolescent; Adult; Androstenedione; Body Mass Index; Dehydroepiandrosterone; Dehydroepiandrosterone | 1996 |
No changes of peripheral insulin resistance in polycystic ovary syndrome after long-term reduction of endogenous androgens with leuprolide.
Topics: Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; F | 1995 |
Dehydroepiandrosterone, dehydroepiandrosterone sulfate, obesity, waist-hip ratio, and noninsulin-dependent diabetes in postmenopausal women: the Rancho Bernardo Study.
Topics: Aged; Aged, 80 and over; Blood Glucose; Cross-Sectional Studies; Dehydroepiandrosterone; Dehydroepia | 1996 |
DHEA diminishes fat food intake in lean and obese Zucker rats.
Topics: Animals; Dehydroepiandrosterone; Dietary Fats; Dose-Response Relationship, Drug; Energy Intake; Feed | 1995 |
A paradoxical elevation of brain cyclo(His-Pro) levels in hyperphagic obese Zucker rats.
Topics: Animals; Brain; Dehydroepiandrosterone; Dipeptides; Hyperphagia; Hypothalamus; Male; Obesity; Rats; | 1995 |
Obesity and endocrine disorders in women taking valproate for epilepsy.
Topics: Adult; Body Weight; Carbamazepine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Endocrine | 1996 |
Influence of some biological indexes on sex hormone-binding globulin and androgen levels in aging or obese males.
Topics: Adult; Aged; Aged, 80 and over; Aging; Androgens; Body Mass Index; Dehydroepiandrosterone; Dehydroep | 1996 |
The antiobesity effect of dehydroepiandrosterone in castrated or noncastrated obese Zucker male rats.
Topics: Animals; Dehydroepiandrosterone; Kinetics; Male; Obesity; Orchiectomy; Rats; Rats, Zucker; Weight Ga | 1995 |
Disparate effects of weight reduction by diet on serum dehydroepiandrosterone-sulfate levels in obese men and women.
Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Male; Obesity; Weight Loss | 1996 |
Dehydroepiandrosterone and insulinaemia.
Topics: Arteriosclerosis; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes Mellitus; Humans; | 1995 |
[Obesity and associated metabolic disorders].
Topics: Dehydroepiandrosterone; Female; Humans; Male; Obesity | 1995 |
Effect of obesity on prostatic hyperplasia: its relation to sex steroid levels.
Topics: Aged; Androgens; Dehydroepiandrosterone; Estradiol; Humans; Male; Middle Aged; Obesity; Organ Size; | 1996 |
Pituitary-adrenocortical function in abdominal obesity of males: evidence for decreased 21-hydroxylase activity.
Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Adult; Androstenedione; Body Constitution | 1996 |
Central effects of dehydroepiandrosterone in Zucker rats.
Topics: Animals; Biogenic Monoamines; Central Nervous System; Dehydroepiandrosterone; Disease Models, Animal | 1995 |
Insulin-like growth factors and their binding proteins before and after weight loss and their associations with hormonal and metabolic parameters in obese adolescent girls.
Topics: Adolescent; Age Factors; Blood Pressure; Body Constitution; Body Mass Index; Cholesterol; Dehydroepi | 1996 |
Body fat accumulation is possibly responsible for lower dehydroepiandrosterone circulating levels in premenopausal obese women.
Topics: Adipose Tissue; Adult; Androstenedione; Anthropometry; Body Constitution; Body Mass Index; Dehydroep | 1996 |
Differential stimulation of cortisol and dehydroepiandrosterone levels by food in obese and normal subjects: relation to body fat distribution.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Adult; Blood Glucose; Body Composition; Body Constituti | 1996 |
Relationships between endogenous steroid hormone, sex hormone-binding globulin and lipoprotein levels in men: contribution of visceral obesity, insulin levels and other metabolic variables.
Topics: Adipose Tissue; Adult; Androstenediol; Androstenedione; Apolipoproteins B; Cholesterol; Cholesterol, | 1997 |
DHEA protects against visceral obesity and muscle insulin resistance in rats fed a high-fat diet.
Topics: Animals; Biological Transport; Body Weight; Dehydroepiandrosterone; Deoxyglucose; Dietary Fats; Insu | 1997 |
DHEA protects against visceral obesity and muscle insulin resistance in rats fed a high-fat diet.
Topics: Animals; Biological Transport; Body Weight; Dehydroepiandrosterone; Deoxyglucose; Dietary Fats; Insu | 1997 |
DHEA protects against visceral obesity and muscle insulin resistance in rats fed a high-fat diet.
Topics: Animals; Biological Transport; Body Weight; Dehydroepiandrosterone; Deoxyglucose; Dietary Fats; Insu | 1997 |
DHEA protects against visceral obesity and muscle insulin resistance in rats fed a high-fat diet.
Topics: Animals; Biological Transport; Body Weight; Dehydroepiandrosterone; Deoxyglucose; Dietary Fats; Insu | 1997 |
Hyperinsulinemia and sex hormones in healthy premenopausal women: relative contribution of obesity, obesity type, and duration of obesity.
Topics: Adult; Androstenedione; Body Weight; C-Peptide; Dehydroepiandrosterone; Estradiol; Fasting; Female; | 1998 |
Secretion of major adrenal androgens following ACTH administration in obese women with different body fat distribution.
Topics: 17-alpha-Hydroxyprogesterone; Abdomen; Adrenocorticotropic Hormone; Adult; Androgens; Androstenedion | 1998 |
[Biochemical markers and methods to assess insulin resistance in normal, obese and hyperandrogenic women].
Topics: Adult; Biomarkers; Blood Glucose; Dehydroepiandrosterone; Female; Glucose Tolerance Test; Humans; Hy | 1997 |
Dehydroepiandrosterone decreases serum tumor necrosis factor-alpha and restores insulin sensitivity: independent effect from secondary weight reduction in genetically obese Zucker fatty rats.
Topics: Animals; Body Weight; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Eating; Female; Glucos | 1998 |
Serum leptin concentrations in obese women with Down syndrome and Prader-Willi syndrome.
Topics: Adult; Androstenedione; Body Mass Index; Dehydroepiandrosterone; Down Syndrome; Estradiol; Female; F | 1999 |
Dehydroepiandrosterone alters the growth of stromal vascular cells from human adipose tissue.
Topics: Adipocytes; Adipose Tissue; Adult; Cell Differentiation; Cell Division; Cells, Cultured; Dehydroepia | 1999 |
Visceral obesity and insulin resistance are associated with plasma aldosterone levels in women.
Topics: Absorptiometry, Photon; Adipose Tissue; Adult; Aldosterone; Blood Glucose; Blood Pressure; Body Mass | 1999 |
Visceral obesity and insulin resistance are associated with plasma aldosterone levels in women.
Topics: Absorptiometry, Photon; Adipose Tissue; Adult; Aldosterone; Blood Glucose; Blood Pressure; Body Mass | 1999 |
Visceral obesity and insulin resistance are associated with plasma aldosterone levels in women.
Topics: Absorptiometry, Photon; Adipose Tissue; Adult; Aldosterone; Blood Glucose; Blood Pressure; Body Mass | 1999 |
Visceral obesity and insulin resistance are associated with plasma aldosterone levels in women.
Topics: Absorptiometry, Photon; Adipose Tissue; Adult; Aldosterone; Blood Glucose; Blood Pressure; Body Mass | 1999 |
Synergistic anorectic effect of dehydroepiandrosterone and d-Fenfluramine on the obese Zucker rat.
Topics: Analysis of Variance; Animals; Appetite; Appetite Depressants; Dehydroepiandrosterone; Drug Synergis | 1999 |
Associations between pituitary-adrenocortical function and abdominal obesity, hyperinsulinaemia and dyslipidaemia in normotensive males.
Topics: 17-alpha-Hydroxyprogesterone; Abdomen; Adrenal Cortex; Adult; Body Constitution; Body Mass Index; C- | 1997 |
Dehydroepiandrosterone (DHEA) decreases open-field spontaneous activity of Zucker rats.
Topics: Animals; Appetite Depressants; Brain Chemistry; Dehydroepiandrosterone; Depression, Chemical; Diet; | 1999 |
[Metabolic and hormonal links in obese individuals with and without symptoms of syndrome X].
Topics: Arteriosclerosis; Dehydroepiandrosterone; Diabetes Mellitus; Humans; Insulin Resistance; Lipids; Obe | 2000 |
Adrenal responsiveness to high, low and very low ACTH 1-24 doses in obesity.
Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Function Tests; Adult; Aldosterone; Case-Control Studies; | 2000 |
The effect of dehydroepiandrosterone on Zucker rats selected for fat food preference.
Topics: Animals; Body Weight; Corticosterone; Dehydroepiandrosterone; Dietary Carbohydrates; Dietary Fats; D | 2000 |
Effects of dehydroepiandrosterone and quinapril on nephropathy in obese Zucker rats.
Topics: Actins; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Creatinine; Dehydroepiandros | 2001 |
Long-term oral administration of dehydroepiandrosterone has different effects on energy intake of young lean and obese male Zucker rats when compared to controls of similar metabolic body size.
Topics: Animals; Body Constitution; Body Weight; Dehydroepiandrosterone; Energy Intake; Heterozygote; Homozy | 1999 |
[Derivatives of dehydroepiandrosterone and their changes during a one-day starvation test].
Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Insulin Resistance; M | 2000 |
GG-genotype in the promotor region of uncoupling-protein-1 gene is associated with lower level of dehydroepiandrosterone in type 2 diabetes.
Topics: Aged; Alleles; Blood Pressure; Carrier Proteins; Cholesterol; Dehydroepiandrosterone; Diabetes Melli | 2001 |
Effects of amlodipine on serum levels of adrenal androgens and insulin in hypertensive men with obesity.
Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Dehydroepiandrosterone; Dehydroepiandrosterone Su | 2001 |
Physiological levels and action of dehydroepiandrosterone in Yucatan miniature swine.
Topics: Adjuvants, Immunologic; Animals; Blood Glucose; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfa | 2001 |
DHEA-PC slows the progression of type 2 diabetes (non-insulin-dependent diabetes mellitus) in the ZDF/Gmi-fa/fa rat.
Topics: Animals; Blood Glucose; Dehydroepiandrosterone; Diabetes Mellitus; Diabetes Mellitus, Type 2; Drug C | 2001 |
Dehydroepiandrosterone alters Zucker rat soleus and cardiac muscle lipid profiles.
Topics: Adjuvants, Immunologic; Animals; Body Weight; Dehydroepiandrosterone; Fatty Acids, Monounsaturated; | 2001 |
Hormone profiles in young adults with epilepsy treated with sodium valproate or lamotrigine monotherapy.
Topics: Adult; Anticonvulsants; Blood Glucose; Body Mass Index; Comorbidity; Dehydroepiandrosterone; Epileps | 2001 |
Association of acanthosis nigricans with risk of diabetes mellitus, and hormonal disturbances in arabian females: case-control study.
Topics: Acanthosis Nigricans; Adolescent; Adult; Aged; Aldosterone; Blood Glucose; Blood Pressure; Body Mass | 2001 |
Dehydroepiandrosterone alters phospholipid profiles in Zucker rat muscle tissue.
Topics: Animals; Arachidonic Acid; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Fatty Acids; Heart; In | 2001 |
Dehydroepiandrosterone and dehydroepiandrosterone sulfate dynamics in obesity.
Topics: Adult; Body Height; Body Weight; Carbon Radioisotopes; Dehydroepiandrosterone; Female; Glucuronates; | 1975 |
Proceedings: The production and fate of adrenyl DHEA in normal and overweight subjects.
Topics: Adipose Tissue; Dehydroepiandrosterone; Female; Humans; Male; Obesity; Sulfuric Acid Esters | 1975 |
Dynamic appearance of [4-14C] dehydroepiandrosterone and [7 alpha-3H] dehydroepiandrosterone sulphate metabolites in urine of normal and obese female subjects.
Topics: Adult; Androsterone; Dehydroepiandrosterone; Etiocholanolone; Female; Glucuronates; Humans; Kinetics | 1976 |
Dehydroepiandrosterone concentration in adipose tissue of normal and overweight subjects.
Topics: Adipose Tissue; Adult; Body Height; Body Weight; Chromatography, Gas; Crystallization; Dehydroepiand | 1976 |
Dehydroepiandrosterone. Metabolic effects.
Topics: Adolescent; Adult; Androgens; Animals; Cell Division; Cell Membrane Permeability; Chemical Phenomena | 1976 |
Prevention of obesity in Avy/a mice by dehydroepiandrosterone.
Topics: Animals; Appetite; Body Weight; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Eating; Fe | 1977 |
Steroid hormones and human breast cancer. An hypothesis.
Topics: 17-Ketosteroids; Adrenal Glands; Breast Neoplasms; Cholesterol; Dehydroepiandrosterone; Estradiol; F | 1977 |
Plasma levels of gonadotropins, prolactin, thyroxine, and adrenal and gonadal steroids in obese prepubertal girls.
Topics: Adrenal Cortex Hormones; Aging; Child; Dehydroepiandrosterone; Estradiol; Female; Follicle Stimulati | 1978 |
Lower endogenous androgens predict central adiposity in men.
Topics: Adult; Aged; Androgens; Androstenedione; Body Constitution; Body Mass Index; Cardiovascular Diseases | 1992 |
Antiglucocorticoid action of dehydroepiandrosterone in young obese Zucker rats.
Topics: Analysis of Variance; Animals; Dehydroepiandrosterone; Enzyme Induction; Female; Glucocorticoids; Ki | 1992 |
Increased free testosterone but normal 5 alpha-reduced testosterone metabolites in obese premenopausal women.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Androstane-3,17-diol; Androsterone; Dehydroepiandroste | 1992 |
Lipoprotein abnormalities in hirsute women. II. Compensatory responses of insulin resistance and dehydroepiandrosterone sulfate with obesity.
Topics: Adaptation, Physiological; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Hi | 1992 |
Studies on nuclear binding of dehydroepiandrosterone in hepatocytes.
Topics: Animals; Cell Nucleus; Corticosterone; Dehydroepiandrosterone; Estrone; Female; Liver; Obesity; Rats | 1992 |
The contribution of body composition, substrates, and hormones to the variability in energy expenditure and substrate utilization in premenopausal women.
Topics: Adolescent; Adult; Blood Glucose; Body Composition; C-Peptide; Calorimetry; Dehydroepiandrosterone; | 1992 |
An abnormality of the growth hormone/insulin-like growth factor-I axis in women with polycystic ovary syndrome due to coexistent obesity.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Analysis of Variance; Blood Glucose; Dehydroepiandrosterone; De | 1992 |
Excess weight and precocious pubarche in children: alterations of the adrenocortical hormones.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenal Cortex Hormones; | 1991 |
Low dehydroepiandrosterone circulating levels in premenopausal obese women with very high body mass index.
Topics: Abdomen; Adipose Tissue; Adult; Body Mass Index; C-Peptide; Dehydroepiandrosterone; Female; Glucose | 1991 |
Short-term effects of dehydroepiandrosterone treatment in rats on mitochondrial respiration.
Topics: Acyl Coenzyme A; Animals; Body Weight; Catalase; Dehydroepiandrosterone; Eating; Ethidium; Female; G | 1991 |
Regulation of carnitine acyltransferase synthesis in lean and obese Zucker rats by dehydroepiandrosterone and clofibrate.
Topics: Animals; Carnitine Acyltransferases; Carnitine O-Palmitoyltransferase; Clofibrate; Dehydroepiandrost | 1991 |
Sex steroids, adiposity and smoking in the pathogenesis of idiopathic hirsutism and polycystic ovary syndrome.
Topics: Adrenal Glands; Adult; Androgens; Androstenedione; Body Mass Index; Body Weight; Dehydroepiandroster | 1991 |
Role of adrenal and gonadal androgens in insulin action and metabolism.
Topics: Adrenal Glands; Dehydroepiandrosterone; Erythrocytes; Female; Glucose Tolerance Test; Humans; Hyperp | 1991 |
No acute effect of physiological insulin increase on dehydroepiandrosterone sulfate in women with obesity and/or polycystic ovarian disease.
Topics: Administration, Oral; Adult; Body Mass Index; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate | 1991 |
Sex hormone concentrations in men with angiographically assessed coronary artery disease--relationship to obesity and body fat distribution.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Body Mass Index; Coronary Angiography; Coronary Artery | 1991 |
Bimodal correlation between the circulating insulin level and the production rate of dehydroepiandrosterone: positive correlation in controls and negative correlation in the polycystic ovary syndrome with acanthosis nigricans.
Topics: Acanthosis Nigricans; Adolescent; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Fas | 1990 |
Reduction in body weight and cholesterol in spontaneously obese dogs by dehydroepiandrosterone.
Topics: Animals; Body Weight; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dehydroepiandrosterone; Dog D | 1990 |
Lack of effect of dehydroepiandrosterone in obese men.
Topics: Adipose Tissue; Adult; Body Mass Index; Dehydroepiandrosterone; Drug Administration Schedule; Drug E | 1990 |
Effects of dehydroepiandrosterone treatment in rats with diet-induced obesity.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Cholesterol; Dehydroepiandrosterone; Energy Int | 1990 |
Androgen response to endogenous insulin secretion during the frequently sampled intravenous glucose tolerance test in normal and hyperandrogenic women.
Topics: Adult; Androgens; Androstenedione; Blood Glucose; Dehydroepiandrosterone; Female; Glucose Tolerance | 1990 |
Glucagon in women with polycystic ovary syndrome (PCO): relationship to abnormalities of insulin and androgens.
Topics: Adult; Androgens; Androstenedione; Blood Glucose; Dehydroepiandrosterone; Dehydroepiandrosterone Sul | 1990 |
[Effect of androgen on the onset of diabetes in the KK mice treated with monosodium aspartate].
Topics: Age Factors; Androgens; Animals; Aspartic Acid; Blood Glucose; Castration; Dehydroepiandrosterone; D | 1989 |
Comparison of dehydroepiandrosterone and clofibric acid treatments in obese Zucker rats.
Topics: Animals; Blood Glucose; Body Weight; Clofibrate; Clofibric Acid; Dehydroepiandrosterone; Disease Mod | 1989 |
Antiobesity effects of etiocholanolones in diabetes (db), viable yellow (Avy), and normal mice.
Topics: Animals; Blood Glucose; Body Weight; Dehydroepiandrosterone; Diabetes Mellitus; Diabetes Mellitus, E | 1985 |
Obesity, acanthosis nigricans, insulin resistance, and hyperandrogenemia: pediatric perspective and natural history.
Topics: Acanthosis Nigricans; Adolescent; Androstenedione; Body Weight; Child; Dehydroepiandrosterone; Femal | 1985 |
Anti-obesity effect of two different levels of dehydroepiandrosterone in lean and obese middle-aged female Zucker rats.
Topics: Adipose Tissue; Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Eating; Fatty Aci | 1986 |
Maintenance of normal circulating levels of delta 4-androstenedione and dehydroepiandrosterone in simple obesity despite increased metabolic clearance rates: evidence for a servo-control mechanism.
Topics: Adult; Androstenedione; Biomechanical Phenomena; Dehydroepiandrosterone; Female; Humans; Metabolic C | 1987 |
Effects of dehydroepiandrosterone on obesity and glucose-6-phosphate dehydrogenase activity in the lethal yellow mouse (strain 129/Sv-Ay/Aw).
Topics: Animals; Body Weight; Dehydroepiandrosterone; Female; Genes, Lethal; Genotype; Glucosephosphate Dehy | 1987 |
Adrenalectomy and steroid treatment in obese (ob/ob) and diabetic (db/db) mice.
Topics: Adrenal Glands; Adrenalectomy; Animals; Body Weight; Cortisone; Dehydroepiandrosterone; Desoxycortic | 1987 |
The impact of obesity and chronic hyperinsulinemia on gonadotropin release and gonadal steroid secretion in the polycystic ovary syndrome.
Topics: Adolescent; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradio | 1988 |
Effects of short-term dehydroepiandrosterone treatment on serum and pancreatic insulin in Zucker rats.
Topics: Adipose Tissue; Animals; Dehydroepiandrosterone; Female; Glucose; Insulin; Obesity; Organ Size; Panc | 1988 |
Obesity and postmenopausal bone loss: the influence of obesity on vertebral density and bone turnover in postmenopausal women.
Topics: Aged; Bone and Bones; Calcium; Calcium-Binding Proteins; Dehydroepiandrosterone; Estradiol; Female; | 1987 |
Effect of short-term DHEA administration on liver metabolism of lean and obese rats.
Topics: Adipose Tissue; Animals; Body Weight; Coenzyme A; Coenzyme A Ligases; Dehydroepiandrosterone; Eating | 1988 |
Therapeutic effects of dehydroepiandrosterone (DHEA) and its metabolites in obese-hyperglycemic mutant mice.
Topics: Animals; Blood Glucose; Body Weight; Dehydroepiandrosterone; Hyperglycemia; Insulin; Mice; Mice, Inb | 1988 |
Relative sensitivity and responsivity of serum cortisol and two adrenal androgens to alpha-adrenocorticotropin-(1-24) in normal and obese, nonhirsute, eumenorrheic women.
Topics: Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Adult; Androstenedione; Cosyntropin; Deh | 1986 |
Glucose metabolism in isolated adipocytes from lean and obese Zucker rats following treatment with dehydroepiandrosterone.
Topics: Adipose Tissue; Administration, Oral; Animals; Blood Glucose; Body Weight; Dehydroepiandrosterone; F | 1985 |
Chronic administration of dehydroepiandrosterone reduces pancreatic beta-cell hyperplasia and hyperinsulinemia in genetically obese Zucker rats.
Topics: Animals; Blood Glucose; Dehydroepiandrosterone; Female; Hyperinsulinism; Hyperplasia; Insulin; Islet | 1985 |
A possible interrelation between glucose-6-phosphate dehydrogenase and dehydroepiandrosterone in obesity.
Topics: Adolescent; Adult; Body Weight; Dehydroepiandrosterone; Erythrocytes; Female; Glucosephosphate Dehyd | 1967 |
Effect of thyroid funtion and of obesity on discriminant function for mammary carcinoma.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Androgens; Androsterone; Breast Neoplasms; | 1968 |
[Menopause and metabolic disorders].
Topics: Dehydroepiandrosterone; Female; Humans; Menopause; Metabolic Diseases; Middle Aged; Obesity | 1965 |
Influence of a low-calorie diet and fasting on the metabolism of dehydroepiandosterone sulfate in adult obese subjects.
Topics: Adult; Androsterone; Carbon Isotopes; Chemistry, Clinical; Chromatography, Gas; Chromatography, Thin | 1968 |
A comparison of urinary 17-hydroxycorticosteroid and 11-deoxy-17-oxosteroid excretion in obesity, in thyroid dysfunction and in early breast cancer.
Topics: 17-Hydroxycorticosteroids; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; | 1969 |
Narcolepsy: increased urinary secretion of estriol.
Topics: Adult; Androsterone; Cataplexy; Dehydroepiandrosterone; Erectile Dysfunction; Estriol; Etiocholanolo | 1970 |
Effect of hormones on fatty acid release and glucose-6-phosphate dehydrogenase activity in human adipose tissue in relation to obesity.
Topics: Adipose Tissue; Dehydroepiandrosterone; Epinephrine; Fatty Acids, Nonesterified; Female; Glucosephos | 1970 |
Testosterone production and metabolism in obese males.
Topics: Adult; Androsterone; Carbon Isotopes; Dehydroepiandrosterone; Etiocholanolone; Humans; Male; Obesity | 1971 |
Plasma androgen and cytogenetic studies of a patient with Morgagni's syndrome.
Topics: Adult; Androgens; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hyperostosis Frontalis Interna; | 1971 |
[Effects of steroids on glucose-6-phosphate dehydrogenase and lipid metabolism].
Topics: Adult; Androstanes; Androsterone; Blood Protein Disorders; Dehydroepiandrosterone; Female; Glucoseph | 1972 |
[Metabolic complications of obesity--attempt to influence them by dehydroepiandrosterone sulfate].
Topics: Adult; Body Weight; Dehydroepiandrosterone; Glucosephosphate Dehydrogenase; Humans; Hyperlipidemias; | 1973 |
Plasma androsterone, dehydroepiandrosterone and 11-hydroxycorticoids in obesity. Effects of diet and physical activity.
Topics: 11-Hydroxycorticosteroids; Adult; Androsterone; Body Height; Body Weight; Dehydroepiandrosterone; Di | 1972 |
[Late gestosis and obesity in long-term study after birth].
Topics: Adult; Dehydroepiandrosterone; Female; Humans; Obesity; Postpartum Period; Pre-Eclampsia; Pregnancy; | 1973 |
Effect of age, obesity, starvation, and changes in adrenocortical and ovarian activity on the urinary excretion of dehydroepiandrosterone relative to androsterone plus etiocholanolone: relevance to the measurement of breast cancer discriminants in women.
Topics: Adrenal Glands; Age Factors; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Dexamethasone; | 1974 |
Slipped upper femoral epiphysis. Clinical study on aetiology.
Topics: 17-Ketosteroids; Adolescent; Age Determination by Skeleton; Age Factors; Androgens; Body Height; Bod | 1968 |
Rapid gas chromatographic assay for dehydroepiandrosterone in urine.
Topics: Adolescent; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Chorionic Gonadotropi | 1971 |
The role of DHA in the pathogenesis of obesity and its metabolic complications.
Topics: Amino Acids; Arteriosclerosis; Cholesterol; Dehydroepiandrosterone; Diabetes Mellitus; Fatty Acids; | 1969 |