dehydroepiandrosterone has been researched along with Neoplasms in 74 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Topical interventions (vaginal gels or creams) were able to alleviate vaginal dryness and dyspareunia, with intravaginal dehydroepiandrosterone (DHEA) (6." | 5.22 | Efficacy of interventions to manage sexual dysfunction in women with cancer: a systematic review. ( Febrina, F; Marino, JL; Peate, M; Triyoga, IF; White, M, 2022) |
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| " The author's own findings and the data available in the literature indicate that the androgens dehydroepiandrosterone and dehydroepiandrosterone sulfate that are secreted in the reticular area play an important role in ensuring the body's full stable adaptation to stress and simultaneously preventing stress-associated abnormalities, such as atherosclerosis, diabetes, immunodefficiency, hypertension, allergies, and cancer." | 4.80 | [Dehydroepiandrosterone, reticular area of adrenal cortex and resistance to stress and disease]. ( Obut, TA, 1998) |
| "16alpha-Hydroxydehydroepiandrosterone is the precursor of fetal 16alpha-hydroxylated estrogens, the main phenolic steroids in pregnancy." | 4.80 | Minireview: 16alpha-hydroxylated metabolites of dehydroepiandrosterone and their biological significance. ( Hampl, R; Starka, L, 2000) |
| "Using croton oil-induced ear edema model and applying confocal laser scanning microscopy, flow cytometry, immuno-fluorescent techniques to investigate the inhibitory effect of DHEA on tumor promotion." | 3.71 | [Studies on the anti-tumorpromotion activities of dehydroepiandrosterone and its mechanism of action]. ( Fu, ZD; Han, R; Yang, S, 2001) |
| "Urinary estradiol production rates, plasma estradiol, and peripheral conversion of dehydroepiandrosterone sulfate (DHEAS) to estradiol were explored in patients whose neoplasms made human chorionic gonadotropin and/or human chorionic gonadotropin beta fragments." | 3.66 | Estrogen production as a tumor marker in patients with gonadotropin-producing neoplasms. ( Berkowitz, R; Drejka, M; Kirschner, MA; Lippman, A; Mayrer, E, 1981) |
| "Dehydroepiandrosterone (DHEA) is a multifunctional steroid with a broad range of biological effects in humans and animals." | 2.48 | Oxidative metabolism of dehydroepiandrosterone (DHEA) and biologically active oxygenated metabolites of DHEA and epiandrosterone (EpiA)--recent reports. ( El Kihel, L, 2012) |
| " Particular attention is paid to the dosage and route of administration." | 2.40 | The actions of exogenous dehydroepiandrosterone in experimental animals and humans. ( Porter, JR; Svec, F, 1998) |
| "All deaths due to cancer (n = 1040), cardiovascular diseases (n = 598), and all causes (n = 2407) that occurred in EPIC-Heidelberg until end of 2014 were included." | 1.91 | Dehydroepiandrosterone Sulfate and Mortality in Middle-Aged and Older Men and Women-A J-shaped Relationship. ( Johnson, T; Kaaks, R; Katzke, V; Mukama, T, 2023) |
| "Breast cancer is the most common tumor among women throughout the world." | 1.91 | The relationship between coping self-efficacy and B cells in breast cancer patients. ( Chesney, MA; El-Amir, A; El-Baiomy, EM; Kassem, L; Sabry, NA; Wallston, KA, 2023) |
| "Here, we established SDHB knockout cancer cell lines from human colon cancer HCT116 cells using the clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 knockout system, and clarified its metabolic characteristics." | 1.46 | Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors. ( Ando, A; Baba, Y; Ebara, S; Hara, T; Kitazawa, S; Satomi, Y; Soga, T, 2017) |
| "The panel cancer cells used in this study were the following: PC-3, MCF-7 and SKLU-1." | 1.39 | Cytotoxic effect of novel dehydroepiandrosterone derivatives on different cancer cell lines. ( Bratoeff, E; Cabeza, M; Cortés, F; Garrido, M; Gutiérrez, J, 2013) |
| "Dehydroepiandrosterone (DHEA) is a naturally occurring steroid synthesized in the adrenal cortex, gonads, brain, and gastrointestinal tract, and it is known to have chemopreventive and anti-proliferative actions on tumors." | 1.32 | Anti-proliferative action of endogenous dehydroepiandrosterone metabolites on human cancer cell lines. ( Fujimoto, Y; Fukushima, S; Honda, A; Matsuzaki, Y; Miyazaki, H; Salen, G; Takagiwa, A; Tanaka, N; Yoshida, S, 2003) |
| "Evidence suggests that adult cancer risk of hormonally related tumors may be influenced by the in utero environment, and most speculation on the biological mechanism has focused on the hormonal component." | 1.32 | Correlation of serum hormone concentrations in maternal and umbilical cord samples. ( Cole, B; Harger, G; Hoover, RN; Lykins, D; Markovic, N; Potischman, N; Roberts, JM; Siiteri, P; Troisi, R, 2003) |
| "Seven ovarian tumors were localized." | 1.26 | [Diagnosis in progressive hirsutism. Catheter technique and results (author's transl)]. ( Moltz, L; Sörensen, R, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (31.08) | 18.7374 |
| 1990's | 13 (17.57) | 18.2507 |
| 2000's | 23 (31.08) | 29.6817 |
| 2010's | 9 (12.16) | 24.3611 |
| 2020's | 6 (8.11) | 2.80 |
| Authors | Studies |
|---|---|
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| Shervington, LA | 1 |
| Smith, N | 1 |
| Norman, E | 1 |
| Ward, T | 1 |
| Phillips, R | 1 |
| Shervington, A | 1 |
| Koperniku, A | 1 |
| Garcia, AA | 1 |
| Mochly-Rosen, D | 1 |
| Febrina, F | 1 |
| Triyoga, IF | 1 |
| White, M | 1 |
| Marino, JL | 1 |
| Peate, M | 1 |
| Mukama, T | 2 |
| Johnson, T | 2 |
| Katzke, V | 2 |
| Kaaks, R | 2 |
| Augimeri, G | 1 |
| Bonofiglio, D | 1 |
| El-Amir, A | 1 |
| El-Baiomy, EM | 1 |
| Sabry, NA | 1 |
| Kassem, L | 1 |
| Chesney, MA | 1 |
| Wallston, KA | 1 |
| Xu, C | 1 |
| Yang, H | 1 |
| Xiao, Z | 1 |
| Zhang, T | 1 |
| Guan, Z | 1 |
| Chen, J | 1 |
| Lai, H | 1 |
| Xu, X | 1 |
| Huang, Y | 1 |
| Huang, Z | 1 |
| Zhao, C | 1 |
| Kitazawa, S | 1 |
| Ebara, S | 1 |
| Ando, A | 1 |
| Baba, Y | 1 |
| Satomi, Y | 1 |
| Soga, T | 1 |
| Hara, T | 1 |
| Garrido, M | 1 |
| Cabeza, M | 1 |
| Cortés, F | 1 |
| Gutiérrez, J | 1 |
| Bratoeff, E | 1 |
| Ohlsson, C | 1 |
| Vandenput, L | 1 |
| Tivesten, A | 1 |
| Ke, S | 1 |
| Shi, L | 1 |
| Zhang, Z | 1 |
| Yang, Z | 1 |
| Gidron, Y | 1 |
| Ronson, A | 1 |
| Omura, Y | 3 |
| Herman, WA | 1 |
| Seńko, A | 1 |
| Korczowska, I | 1 |
| Łacka, K | 1 |
| Hines, H | 1 |
| Jones, M | 1 |
| O'Young, B | 1 |
| Duvvi, H | 1 |
| Lu, DP | 1 |
| Pallos, A | 1 |
| Shimotsuura, Y | 1 |
| Ohki, M | 1 |
| Pizza, V | 1 |
| Agresta, A | 1 |
| D'Acunto, CW | 1 |
| Festa, M | 1 |
| Capasso, A | 1 |
| El Kihel, L | 1 |
| Liu, XK | 1 |
| Ye, BJ | 1 |
| Wu, Y | 1 |
| Nan, JX | 1 |
| Lin, ZH | 1 |
| Piao, HR | 1 |
| Gravanis, A | 1 |
| Calogeropoulou, T | 1 |
| Panoutsakopoulou, V | 1 |
| Thermos, K | 1 |
| Neophytou, C | 1 |
| Charalampopoulos, I | 1 |
| Moyad, MA | 1 |
| Yoshida, S | 1 |
| Honda, A | 1 |
| Matsuzaki, Y | 1 |
| Fukushima, S | 1 |
| Tanaka, N | 1 |
| Takagiwa, A | 1 |
| Fujimoto, Y | 1 |
| Miyazaki, H | 1 |
| Salen, G | 1 |
| Yang, S | 1 |
| Fu, ZD | 1 |
| Han, R | 1 |
| Troisi, R | 1 |
| Potischman, N | 1 |
| Roberts, JM | 1 |
| Harger, G | 1 |
| Markovic, N | 1 |
| Cole, B | 1 |
| Lykins, D | 1 |
| Siiteri, P | 1 |
| Hoover, RN | 1 |
| PESONEN, S | 1 |
| MIKKONEN, R | 1 |
| ZARA, M | 1 |
| LUMBROSO, A | 1 |
| TRETBAR, HA | 1 |
| CAWLEY, LP | 1 |
| ARPELS, C | 1 |
| BABCOCK, VI | 1 |
| SOUTHAM, CM | 1 |
| PIPINO, G | 1 |
| SCHUBERT, K | 1 |
| BACIGALUPO, G | 1 |
| Binello, E | 1 |
| Gordon, CM | 1 |
| Nakamura, S | 1 |
| Yoshimura, M | 1 |
| Nakayama, M | 1 |
| Ito, T | 1 |
| Mizuno, Y | 1 |
| Harada, E | 1 |
| Sakamoto, T | 1 |
| Saito, Y | 1 |
| Nakao, K | 1 |
| Yasue, H | 1 |
| Ogawa, H | 1 |
| Bradlow, HL | 1 |
| Sepkovic, DW | 1 |
| Howard, JM | 2 |
| Olech, E | 1 |
| Merrill, JT | 1 |
| Payne, JK | 1 |
| Glover, DA | 1 |
| Stuber, M | 1 |
| Poland, RE | 1 |
| MASON, HL | 1 |
| KEPLER, EJ | 1 |
| SCHNEIDER, JJ | 1 |
| Sörensen, R | 1 |
| Moltz, L | 1 |
| Kirschner, MA | 1 |
| Lippman, A | 1 |
| Berkowitz, R | 1 |
| Mayrer, E | 1 |
| Drejka, M | 1 |
| Hursting, SD | 1 |
| Perkins, SN | 1 |
| Haines, DC | 1 |
| Ward, JM | 1 |
| Phang, JM | 1 |
| Khorram, O | 1 |
| McCarty, MF | 1 |
| Herrington, DM | 1 |
| Svec, F | 1 |
| Porter, JR | 1 |
| Obut, TA | 1 |
| Nippoldt, TB | 1 |
| Nair, KS | 1 |
| Sirrs, SM | 1 |
| Bebb, RA | 1 |
| Ciolino, HP | 1 |
| Yeh, GC | 1 |
| Martin-Du Pan, RC | 1 |
| Hampl, R | 1 |
| Starka, L | 1 |
| Rigaud, AS | 1 |
| Pellerin, J | 1 |
| Levi, MS | 1 |
| Borne, RF | 1 |
| Williamson, JS | 1 |
| Mezalek, ZT | 1 |
| Zdrojewicz, Z | 1 |
| Kesik, S | 1 |
| Kelloff, GJ | 1 |
| Malone, WF | 1 |
| Boone, CW | 1 |
| Sigman, CC | 1 |
| Fay, JR | 1 |
| Estabrook, RW | 1 |
| Milewich, L | 1 |
| Prough, RA | 1 |
| Schwartz, A | 1 |
| Gordon, GB | 1 |
| Shantz, LM | 1 |
| Talalay, P | 1 |
| Regelson, W | 2 |
| Loria, R | 1 |
| Kalimi, M | 1 |
| Schwartz, AG | 1 |
| Whitcomb, JM | 1 |
| Nyce, JW | 1 |
| Lewbart, ML | 1 |
| Pashko, LL | 1 |
| Kvedar, JC | 1 |
| Gibson, M | 1 |
| Krusinski, PA | 1 |
| Uemura, J | 1 |
| Okamura, T | 1 |
| Noto, S | 1 |
| Kida, R | 1 |
| Garnham, JR | 1 |
| Bulbrook, RD | 1 |
| Wang, DY | 1 |
| Sonka, J | 1 |
| Vítková, M | 1 |
| Gregorová, I | 1 |
| Tomsová, Z | 1 |
| Hilgertová, J | 1 |
| Staś, J | 1 |
| Strubel, HB | 1 |
| Rindt, W | 1 |
| Hoffmann, G | 1 |
| Schirazi, M | 1 |
| Oertel, GW | 1 |
| Sekihara, H | 1 |
| Ri, H | 1 |
| Osawa, N | 1 |
| Kosaka, K | 1 |
| Riessbeck, KH | 2 |
| Saez, JM | 1 |
| Morera, AM | 1 |
| Dazord, A | 1 |
| Bertrand, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Biological Effects of DHEA in the Elderly[NCT00111930] | 144 participants | Interventional | 2000-08-31 | Completed | |||
| Effect of DHEA on Skin Aging - Placebo-Controlled and Randomized Phase III Study in Postmenopausal Women.[NCT00248989] | Phase 3 | 150 participants (Actual) | Interventional | 2004-11-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
29 reviews available for dehydroepiandrosterone and Neoplasms
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
Boosting the Discovery of Small Molecule Inhibitors of Glucose-6-Phosphate Dehydrogenase for the Treatment of Cancer, Infectious Diseases, and Inflammation.
Topics: Communicable Diseases; Drug Discovery; Glucosephosphate Dehydrogenase; High-Throughput Screening Ass | 2022 |
Efficacy of interventions to manage sexual dysfunction in women with cancer: a systematic review.
Topics: Cancer Survivors; Dehydroepiandrosterone; Dyspareunia; Female; Humans; Male; Neoplasms; Randomized C | 2022 |
Promising Effects of
Topics: Animals; Dehydroepiandrosterone; Docosahexaenoic Acids; Eicosapentaenoic Acid; Ethanolamine; Fatty A | 2023 |
DHEA and mortality: what is the nature of the association?
Topics: Adrenal Glands; Cardiovascular Diseases; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Fem | 2015 |
Psychosocial factors, biological mediators, and cancer prognosis: a new look at an old story.
Topics: Animals; Anxiety; Dehydroepiandrosterone; Humans; Hypothalamo-Hypophyseal System; Neoplasms; Pituita | 2008 |
Neuroinflammation and ageing: current theories and an overview of the data.
Topics: Aging; Alzheimer Disease; Apoptosis; Atherosclerosis; Biological Evolution; Brain; Cellular Senescen | 2011 |
Oxidative metabolism of dehydroepiandrosterone (DHEA) and biologically active oxygenated metabolites of DHEA and epiandrosterone (EpiA)--recent reports.
Topics: Androsterone; Animals; Brain; Cardiovascular Diseases; Dehydroepiandrosterone; Female; Humans; Hydro | 2012 |
The placebo effect and randomized trials: analysis of alternative medicine.
Topics: Androstenedione; Antioxidants; beta Carotene; Coenzymes; Complementary Therapies; Dehydroepiandroste | 2002 |
Clinical uses and misuses of dehydroepiandrosterone.
Topics: Adjuvants, Immunologic; Autoimmune Diseases; Cardiovascular Diseases; Clinical Trials as Topic; Dehy | 2003 |
Steroids as procarcinogenic agents.
Topics: Androgens; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Cytochrome P-45 | 2004 |
DHEA supplementation: the claims in perspective.
Topics: Adjuvants, Immunologic; Dehydroepiandrosterone; Dietary Supplements; Humans; Neoplasms | 2005 |
The trajectory of biomarkers in symptom management for older adults with cancer.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aged; Aging; Anxiety; Biomarkers; Biomarkers, Tumor; Cy | 2006 |
DHEA: a hormone with multiple effects.
Topics: Aged; Biomarkers; Bone Density; Brain; Cardiovascular Diseases; Dehydroepiandrosterone; Estrogen Rep | 1996 |
The actions of exogenous dehydroepiandrosterone in experimental animals and humans.
Topics: Animals; Cardiovascular System; Dehydroepiandrosterone; Female; Humans; Immunity; Male; Metabolism; | 1998 |
[Dehydroepiandrosterone, reticular area of adrenal cortex and resistance to stress and disease].
Topics: Adjuvants, Immunologic; Animals; Arteriosclerosis; Dehydroepiandrosterone; Dehydroepiandrosterone Su | 1998 |
Is there a case for DHEA replacement?
Topics: Adult; Aged; Aging; Alzheimer Disease; Animals; Arteriosclerosis; Bone Remodeling; Carbohydrate Meta | 1998 |
DHEA: panacea or snake oil?
Topics: Adjuvants, Immunologic; Aging; Dehydroepiandrosterone; Female; Heart Diseases; Humans; Immune System | 1999 |
[Are the hormones of youth carcinogenic?].
Topics: Aging; Dehydroepiandrosterone; Estrogens; Female; Hormones; Human Growth Hormone; Humans; Insulin-Li | 1999 |
Minireview: 16alpha-hydroxylated metabolites of dehydroepiandrosterone and their biological significance.
Topics: Autoimmune Diseases; Body Fluids; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Estrogens; | 2000 |
[Neuropsychic effects of dehydroepiandrosterone].
Topics: Affect; Aging; Animals; Attention; Cardiovascular Diseases; Dehydroepiandrosterone; Dehydroepiandros | 2001 |
A review of cancer chemopreventive agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Dehydroepiandrosterone; F | 2001 |
[Dehydroepiandrosterone (DHEA)--youth hormone?].
Topics: Aging; Arteriosclerosis; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes | 2001 |
Progress in applied chemoprevention research.
Topics: Animals; Antineoplastic Agents; Dehydroepiandrosterone; Drug Evaluation; Eflornithine; Fenretinide; | 1990 |
Cytochrome P-450s as toxicogenic catalysts: the influence of dehydroepiandrosterone.
Topics: Animals; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Dose-Response Relationship, Drug; G | 1990 |
Modulation of growth, differentiation and carcinogenesis by dehydroepiandrosterone.
Topics: Adipose Tissue; Animals; Body Weight; Cell Differentiation; Cell Division; Dehydroepiandrosterone; D | 1987 |
Hormonal intervention: "buffer hormones" or "state dependency". The role of dehydroepiandrosterone (DHEA), thyroid hormone, estrogen and hypophysectomy in aging.
Topics: Aging; Animals; Cell Transformation, Neoplastic; Dehydroepiandrosterone; Diabetes Mellitus; Estrogen | 1988 |
Dehydroepiandrosterone and structural analogs: a new class of cancer chemopreventive agents.
Topics: Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Male; Neoplasms; Ne | 1988 |
Hirsutism: evaluation and treatment.
Topics: Contraceptives, Oral; Dehydroepiandrosterone; Dexamethasone; Dihydrotestosterone; Female; Hair Remov | 1985 |
1 trial available for dehydroepiandrosterone and Neoplasms
| Article | Year |
|---|---|
Beneficial effects and side effects of DHEA: true anti-aging and age-promoting effects, as well as anti-cancer and cancer-promoting effects of DHEA evaluated from the effects on the normal and cancer cell telomeres and other parameters.
Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Aging; Antineoplastic Agents; Chromosome Abe | 2005 |
44 other studies available for dehydroepiandrosterone and Neoplasms
| Article | Year |
|---|---|
To determine the cytotoxicity of chlorambucil and one of its nitro-derivatives, conjugated to prasterone and pregnenolone, towards eight human cancer cell-lines.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chlorambucil; Chromatography, High Pressure Liquid | 2009 |
Dehydroepiandrosterone Sulfate and Mortality in Middle-Aged and Older Men and Women-A J-shaped Relationship.
Topics: Aged; Cardiovascular Diseases; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Human | 2023 |
Dehydroepiandrosterone Sulfate and Mortality in Middle-Aged and Older Men and Women-A J-shaped Relationship.
Topics: Aged; Cardiovascular Diseases; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Human | 2023 |
Dehydroepiandrosterone Sulfate and Mortality in Middle-Aged and Older Men and Women-A J-shaped Relationship.
Topics: Aged; Cardiovascular Diseases; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Human | 2023 |
Dehydroepiandrosterone Sulfate and Mortality in Middle-Aged and Older Men and Women-A J-shaped Relationship.
Topics: Aged; Cardiovascular Diseases; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Human | 2023 |
The relationship between coping self-efficacy and B cells in breast cancer patients.
Topics: Adaptation, Psychological; Dehydroepiandrosterone; Female; Flow Cytometry; Humans; Lymphocyte Count; | 2023 |
Reduction-responsive dehydroepiandrosterone prodrug nanoparticles loaded with camptothecin for cancer therapy by enhancing oxidation therapy and cell replication inhibition.
Topics: Camptothecin; Cell Line, Tumor; Dehydroepiandrosterone; DNA Replication; Drug Delivery Systems; Huma | 2021 |
Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors.
Topics: Antineoplastic Agents; Azepines; Benzodiazepines; Citric Acid Cycle; CRISPR-Cas Systems; Dehydroepia | 2017 |
Cytotoxic effect of novel dehydroepiandrosterone derivatives on different cancer cell lines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dehydroepiandrosterone; Humans; Neoplas | 2013 |
Steroidal[17,16-d]pyrimidines derived from dehydroepiandrosterone: A convenient synthesis, antiproliferation activity, structure-activity relationships, and role of heterocyclic moiety.
Topics: Antineoplastic Agents; Cell Proliferation; Dehydroepiandrosterone; Drug Screening Assays, Antitumor; | 2017 |
Organ representation areas of different internal organs localized on the eyebrows & eyelids by the Bi-Digital O-Ring Test electromagnetic resonance phenomenon between 2 identical molecules--Part I: Detection of increased markers for cancer & heart disease
Topics: Aged; Biomarkers; Dehydroepiandrosterone; Early Diagnosis; Eyebrows; Eyelids; Hair Color; Heart Dise | 2008 |
[Could serum DHEA and DHEAS levels be good risk predictors of metabolic syndrome and osteoporosis in the population of ageing men?].
Topics: Adult; Aged; Aged, 80 and over; Aging; Comorbidity; Dehydroepiandrosterone; Dementia; Humans; Hypert | 2009 |
Metal ring on 4th or 5th finger markedly increases both cardiac troponin I at left ventricle and cancer-related parameters such as oncogen C-fosAb2 & integrin α₅β₁[corrected] by 4-12 times. Thus these metal rings appear to promote both heart problems & ca
Topics: Adult; Aged; Dehydroepiandrosterone; Female; Fingers; Heart Diseases; Heart Ventricles; Humans; Inte | 2010 |
Synthesis and antitumor activity of dehydroepiandrosterone derivatives on Es-2, A549, and HepG2 cells in vitro.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Dehydroepiandrosterone; Drug Screening Assay | 2012 |
Neurosteroids and microneurotrophins signal through NGF receptors to induce prosurvival signaling in neuronal cells.
Topics: Androgens; Animals; Apoptosis; Blood-Brain Barrier; Cell Survival; Dehydroepiandrosterone; Estrogens | 2012 |
Anti-proliferative action of endogenous dehydroepiandrosterone metabolites on human cancer cell lines.
Topics: Cell Division; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, D | 2003 |
[Studies on the anti-tumorpromotion activities of dehydroepiandrosterone and its mechanism of action].
Topics: Animals; Anticarcinogenic Agents; Calcium; Croton Oil; Dehydroepiandrosterone; Disease Models, Anima | 2001 |
Correlation of serum hormone concentrations in maternal and umbilical cord samples.
Topics: Adult; Androstenedione; Biomarkers; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiandroste | 2003 |
Observations on the significance of dehydroepiandrosterone, androsterone and etiocholanolone determinations in the differential diagnosis of certain adrenal and ovarian diseases.
Topics: Adrenal Cortex; Adrenal Cortex Diseases; Androgens; Androsterone; Dehydroepiandrosterone; Diagnosis, | 1958 |
[Therapeutic study of a new anabolic drug: nor-androstenolone phenylpropionate].
Topics: Body Weight; Body Weights and Measures; Bone and Bones; Dehydroepiandrosterone; Neoplasms; Osteoporo | 1960 |
CUSHING'S SYNDROME.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Androgens; Androsterone; Carcinoma; Carcinoma, Broncho | 1963 |
EFFECT OF STEROIDS ON HUMAN CELL CULTURES; SUSTAINING EFFECT OF HYDROCORTISONE.
Topics: 17-Ketosteroids; Androsterone; Dehydroepiandrosterone; Estradiol; Etiocholanolone; Hydrocortisone; H | 1964 |
[CLINICAL EVALUATION OF THE PROTEO-ANABOLIC ACTIVITY OF L-METHYL-DELTA ANDROSTENOLONE IN PATIENTS WITH MALIGNANT NEOPLASMS DURING ACTINOTHERAPY].
Topics: Anabolic Agents; Blood Protein Electrophoresis; Breast Neoplasms; Carcinoma, Bronchogenic; Cobalt Is | 1964 |
DIFFERENCES OF STEROID METABOLISM IN BREAST CANCER AFTER HORMONE STIMULATION.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Androgens; Androsterone; Breast Diseases; Breast Neoplasms | 1964 |
Possible association of heart failure status with synthetic balance between aldosterone and dehydroepiandrosterone in human heart.
Topics: Adult; Aged; Aldosterone; Animals; Blotting, Southern; Cardiac Catheterization; Cell Size; Cells, Cu | 2004 |
Breast cancer after childhood cancer.
Topics: Breast Neoplasms; Child; Dehydroepiandrosterone; Female; Humans; Neoplasms; Neoplasms, Second Primar | 2005 |
Allostatic load in women with and without PTSD symptoms.
Topics: Adolescent; Adult; Allostasis; Arousal; Blood Pressure; Body Mass Index; Child; Child, Preschool; Ch | 2006 |
Common factor of cancer and the metabolic syndrome may be low DHEA.
Topics: Dehydroepiandrosterone; Humans; Metabolic Syndrome; Neoplasms; United States | 2007 |
Metabolism of dehydroisoandrosterone in a woman before and after removal of an adrenocortical tumor.
Topics: Adrenal Glands; Biological Assay; Dehydroepiandrosterone; Gonadal Steroid Hormones; Neoplasms | 1949 |
[Diagnosis in progressive hirsutism. Catheter technique and results (author's transl)].
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Catheterization; Cushing Syndrome; Dehydroepia | 1981 |
Estrogen production as a tumor marker in patients with gonadotropin-producing neoplasms.
Topics: Choriocarcinoma; Chorionic Gonadotropin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Est | 1981 |
Chemoprevention of spontaneous tumorigenesis in p53-knockout mice.
Topics: Animals; Anticarcinogenic Agents; Cyclohexenes; Dehydroepiandrosterone; Gene Deletion; Genes, p53; L | 1995 |
Promotion of interleukin-2 activity as a strategy for 'rejuvenating' geriatric immune function.
Topics: Aging; Animals; Antioxidants; Carotenoids; Chromium; Clonal Anergy; Dehydroepiandrosterone; Diet; HI | 1997 |
Clinical development plan: dehydroepiandrosterone (DHEA).
Topics: Aged; Animals; Anticarcinogenic Agents; Clinical Trials, Phase II as Topic; Dehydroepiandrosterone; | 1996 |
DHEA: a biologic conundrum.
Topics: Aging; Alzheimer Disease; Cardiovascular Diseases; Dehydroepiandrosterone; Erectile Dysfunction; Fem | 1998 |
The steroid hormone dehydroepiandrosterone inhibits CYP1A1 expression in vitro by a post-transcriptional mechanism.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Carcinogens; Cytochrome P-450 CYP1A1; Dehydroepiandrosterone; Dehy | 1999 |
[Systemic lupus erythematosus. International Conference on Systemic Lupus Erythematosus, Barcelona, March 24-28, 2001].
Topics: Adjuvants, Immunologic; Age Factors; Antimalarials; Antiphospholipid Syndrome; Cyclophosphamide; Deh | 2002 |
The effects of dehydroepiandrosterone on the rate of development of cancer and autoimmune processes in laboratory rodents.
Topics: Animals; Carcinogens; Dehydroepiandrosterone; Diet, Reducing; Energy Intake; Glucosephosphate Dehydr | 1985 |
Vitamin A, dehydroepiandrosterone (DHEA) and 5' nucleotidase: regulatory factors in tumor growth.
Topics: 5'-Nucleotidase; Dehydroepiandrosterone; Humans; Neoplasms; Nucleotidases; Vitamin A | 1985 |
[Clinical trial of dehydroisoandrosterone for terminal cases of malignant tumors].
Topics: Adult; Aged; Antineoplastic Agents; Dehydroepiandrosterone; Female; Humans; Male; Middle Aged; Neopl | 1966 |
Conjugated and unconjugated dehydroepiandrosterone, aetiocholanolone and androsterone in the peripheral plasma of patients with cancer of the breast, ovary, uterus or prostate.
Topics: Adult; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Male | 1969 |
Plasma and urinary dehydroepiandrosterone in cancer.
Topics: Adult; Age Factors; Aged; Dehydroepiandrosterone; Erythrocytes; Female; Glucosephosphate Dehydrogena | 1973 |
Cytostatic effects of G-6-PDH inhibitors in cell cultures from normal and neoplastic tissue.
Topics: Breast Neoplasms; Cells, Cultured; Dehydroepiandrosterone; DNA; Female; Glucosephosphate Dehydrogena | 1974 |
[Proceedings: Blood 11-deoxy-17-KS, dehydroepiandrosterone (DHEA) in dehydroepiandrosterone sulfate (DHEAS) in the field of internal medicine].
Topics: 17-Ketosteroids; Adult; Dehydroepiandrosterone; Female; Humans; Hypertension; Male; Middle Aged; Neo | 1974 |
[On the importance of examining the reserve of the adrenal cortex with ACTH on the basis of determining dehydroepiandrosterone in urine during the course of radiotherapy].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Chromatography; Dehydroepiandrosterone; Female; Huma | 1967 |
[On a functional examination of the adrenal cortex for the purpose of radiotherapy].
Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Bone Neopl | 1967 |
Adrenal and testicular contribution to plasma oestrogens.
Topics: 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Androstanes; Breast Neopl | 1972 |