dehydroepiandrosterone has been researched along with Myotonic Dystrophy in 6 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Myotonic dystrophy type 1 may be associated with low circulating dehydroepiandrosterone (DHEA) levels." | 9.13 | Dehydroepiandrosterone for myotonic dystrophy type 1. ( Annane, D; Bes, MC; Bouhour, F; Chevret, S; Cintas, P; Desnuelle, C; Devillers, M; Doppler, V; Eymard, B; Ferrer, X; Hogrel, JY; Laforêt, P; Lagrange, E; Orlikowski, D; Pénisson-Besnier, I; Porcher, R; Pouget, J; Sacconi, S; Solé, G; Tranchant, C; Uzenot, D; Vershueren, A; Vial, C; Vila, AL, 2008) |
| "Myotonic dystrophy type 1 may be associated with low circulating dehydroepiandrosterone (DHEA) levels." | 5.13 | Dehydroepiandrosterone for myotonic dystrophy type 1. ( Annane, D; Bes, MC; Bouhour, F; Chevret, S; Cintas, P; Desnuelle, C; Devillers, M; Doppler, V; Eymard, B; Ferrer, X; Hogrel, JY; Laforêt, P; Lagrange, E; Orlikowski, D; Pénisson-Besnier, I; Porcher, R; Pouget, J; Sacconi, S; Solé, G; Tranchant, C; Uzenot, D; Vershueren, A; Vial, C; Vila, AL, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pénisson-Besnier, I | 1 |
| Devillers, M | 1 |
| Porcher, R | 1 |
| Orlikowski, D | 1 |
| Doppler, V | 1 |
| Desnuelle, C | 1 |
| Ferrer, X | 1 |
| Bes, MC | 1 |
| Bouhour, F | 1 |
| Tranchant, C | 1 |
| Lagrange, E | 1 |
| Vershueren, A | 1 |
| Uzenot, D | 1 |
| Cintas, P | 1 |
| Solé, G | 1 |
| Hogrel, JY | 1 |
| Laforêt, P | 1 |
| Vial, C | 1 |
| Vila, AL | 1 |
| Sacconi, S | 1 |
| Pouget, J | 1 |
| Eymard, B | 1 |
| Chevret, S | 1 |
| Annane, D | 1 |
| Turner, C | 1 |
| Hilton-Jones, D | 1 |
| Johansson, A | 1 |
| Henriksson, A | 1 |
| Olofsson, BO | 1 |
| Olsson, T | 1 |
| Takayanagi, R | 1 |
| Hamilton, W | 2 |
| Mitchell, RG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 3 Study of Oral Dehydroepiandrosterone (DHEA) in Adults With Myotonic Dystrophy[NCT00167609] | Phase 2/Phase 3 | 75 participants (Actual) | Interventional | 2004-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for dehydroepiandrosterone and Myotonic Dystrophy
| Article | Year |
|---|---|
The myotonic dystrophies: diagnosis and management.
Topics: Blotting, Southern; Chromosomes, Human, Pair 19; Creatine; Dehydroepiandrosterone; Diagnosis, Differ | 2010 |
1 trial available for dehydroepiandrosterone and Myotonic Dystrophy
| Article | Year |
|---|---|
Dehydroepiandrosterone for myotonic dystrophy type 1.
Topics: Adult; Dehydroepiandrosterone; Double-Blind Method; Endpoint Determination; Female; Humans; Male; Mi | 2008 |
4 other studies available for dehydroepiandrosterone and Myotonic Dystrophy
| Article | Year |
|---|---|
Adrenal steroid dysregulation in dystrophia myotonica.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Androstenedione; Blood Glucose; Case-Control Studies; Circadian | 1999 |
[DHEA, osteoporosis, nuclear receptor and aging].
Topics: Administration, Oral; Aged; Aging; Bone and Bones; Dehydroepiandrosterone; Female; Humans; Male; Mid | 2001 |
Enzyme studies of the testis in myotonic dystrophy.
Topics: 17-Ketosteroids; Adolescent; Androstanes; Child; Dehydroepiandrosterone; Humans; Hydroxysteroid Dehy | 1970 |
Testicular function in myotonic dystrophy of childhood.
Topics: Androstenedione; Autopsy; Biopsy; Carbon Radioisotopes; Child; Child, Preschool; Chromatography, Thi | 1974 |