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dehydroepiandrosterone and Muscle Contraction

dehydroepiandrosterone has been researched along with Muscle Contraction in 20 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"The compensation of the deficit of dehydroepiandrosterone during aging using a 50-mg/d dose does not induce beneficial effects on muscle state in healthy subjects."5.10Effect of 1-year oral administration of dehydroepiandrosterone to 60- to 80-year-old individuals on muscle function and cross-sectional area: a double-blind placebo-controlled trial. ( Baulieu, EE; Denot-Ledunois, S; Fardeau, M; Fayet, G; Forette, F; Hogrel, JY; Marini, JF; Percheron, G, 2003)
"The purpose of this study was to determine the effect of Dehydroepiandrosterone (DHEA) administration alone or exercise combined with DHEA before steroid treatment on rat hindlimb muscles."1.35[Effect of DHEA administration alone or exercise combined with DHEA before steroid treatment on rat hindlimb muscles]. ( An, GJ; Choe, MA, 2009)
"Dehydroepiandrosterone (DHEA) is a multifunctional steroid that is increasingly available as a supplement aimed at improving libido and well-being in postmenopausal women in the recent times."1.35The effects of dehydroepiandrosterone (DHEA)/DHEA-sulfate (DHEAS) on the contraction responses of the clitoral cavernous smooth muscle from female rabbits. ( Kim, KD; Kim, SC; Kim, TH; Kim, WY; Lee, MY; Lee, SY; Myung, SC; Park, SH, 2009)
"Dehydroepiandrosterone sulfate (DHEAS) is an endogenous steroid having a wide variety of biological effects, but its physiological role remains undefined."1.29Effects of dehydroepiandrosterone sulfate on cellular calcium responsiveness and vascular contractility. ( Barbagallo, M; Pang, PK; Resnick, LM; Shan, J, 1995)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19905 (25.00)18.7374
1990's4 (20.00)18.2507
2000's9 (45.00)29.6817
2010's2 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dumas de la Roque, E1
Quignard, JF1
Ducret, T1
Dahan, D1
Courtois, A1
Begueret, H1
Marthan, R1
Savineau, JP1
Bossé, Y1
Choe, MA1
An, GJ1
Lee, SY1
Myung, SC1
Lee, MY1
Kim, TH1
Kim, SC1
Kim, KD1
Park, SH1
Kim, WY1
Percheron, G1
Hogrel, JY1
Denot-Ledunois, S1
Fayet, G1
Forette, F1
Baulieu, EE1
Fardeau, M1
Marini, JF1
Dayal, M1
Sammel, MD1
Zhao, J1
Hummel, AC1
Vandenbourne, K1
Barnhart, KT1
Villareal, DT1
Holloszy, JO1
Minetto, MA1
Paccotti, P1
Borrione, P1
Massazza, G1
Ventura, M1
Termine, A1
Di Luigi, L1
Pigozzi, F1
Angeli, A1
Galvão, DA1
Nosaka, K1
Taaffe, DR1
Peake, J1
Spry, N1
Suzuki, K1
Yamaya, K1
McGuigan, MR1
Kristjanson, LJ1
Newton, RU2
Barbagallo, M1
Shan, J1
Pang, PK1
Resnick, LM1
Niebauer, J1
Pflaum, CD1
Clark, AL1
Strasburger, CJ1
Hooper, J1
Poole-Wilson, PA1
Coats, AJ1
Anker, SD1
Peng, W1
Michael, JR1
Hoidal, JR1
Karwande, SV1
Farrukh, IS1
Morales, AJ1
Haubrich, RH1
Hwang, JY1
Asakura, H1
Yen, SS1
Häkkinen, K1
Pakarinen, A1
Kraemer, WJ1
Alen, M1
Kobayashi, K1
Motohara, T1
Honma, A1
Takahashi, R1
Aihara, M1
Sudo, T1
Yoshizaki, F1
Ishida, Y1
Kondo, N1
Aihara, S1
Nakagawa, H1
Weltman, A1
Janney, C1
Rians, CB1
Strand, K1
Berg, B1
Tippitt, S1
Wise, J1
Cahill, BR1
Katch, FI1
van der Crabben, H1
Hammacher, K1
Werner, C1
Kaiser, E1
Anderson, GG1
Hobbins, JC1
Speroff, L1
Caldwell, BV1
Oakey, RE1
Cawood, ML1
Macdonald, RR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Omega-3 Fatty Acids on Bone and Frailty[NCT00634686]Phase 4150 participants (Anticipated)Interventional2007-01-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for dehydroepiandrosterone and Muscle Contraction

ArticleYear
Endocrine regulation of airway contractility is overlooked.
    The Journal of endocrinology, 2014, Volume: 222, Issue:2

    Topics: Adaptation, Physiological; Adiponectin; Androgens; Animals; Asthma; Bronchodilator Agents; Dehydroep

2014

Trials

4 trials available for dehydroepiandrosterone and Muscle Contraction

ArticleYear
Effect of 1-year oral administration of dehydroepiandrosterone to 60- to 80-year-old individuals on muscle function and cross-sectional area: a double-blind placebo-controlled trial.
    Archives of internal medicine, 2003, Mar-24, Volume: 163, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Double-Blind

2003
Supplementation with DHEA: effect on muscle size, strength, quality of life, and lipids.
    Journal of women's health (2002), 2005, Volume: 14, Issue:5

    Topics: Aged; Androstenedione; Body Composition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dru

2005
DHEA enhances effects of weight training on muscle mass and strength in elderly women and men.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 291, Issue:5

    Topics: Adjuvants, Immunologic; Aged; Aging; Dehydroepiandrosterone; Exercise; Female; Humans; Insulin-Like

2006
The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women.
    Clinical endocrinology, 1998, Volume: 49, Issue:4

    Topics: Aged; Aging; Androstenedione; Body Composition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfa

1998

Other Studies

15 other studies available for dehydroepiandrosterone and Muscle Contraction

ArticleYear
Beneficial effect of dehydroepiandrosterone on pulmonary hypertension in a rodent model of pulmonary hypertension in infants.
    Pediatric research, 2013, Volume: 74, Issue:2

    Topics: Analysis of Variance; Animals; Animals, Newborn; Arterial Pressure; Cell Proliferation; Dehydroepian

2013
[Effect of DHEA administration alone or exercise combined with DHEA before steroid treatment on rat hindlimb muscles].
    Journal of Korean Academy of Nursing, 2009, Volume: 39, Issue:3

    Topics: Animals; Body Weight; Dehydroepiandrosterone; Hindlimb; Male; Muscle Contraction; Muscle, Skeletal;

2009
The effects of dehydroepiandrosterone (DHEA)/DHEA-sulfate (DHEAS) on the contraction responses of the clitoral cavernous smooth muscle from female rabbits.
    The journal of sexual medicine, 2009, Volume: 6, Issue:10

    Topics: Analysis of Variance; Animals; Arousal; Calcium Channels; Clitoris; Dehydroepiandrosterone; Dehydroe

2009
Effects of the training status on the hormonal response and recovery from high-intensity isokinetic exercise: comparisons between endurance-trained athletes and sedentary subjects.
    The Journal of sports medicine and physical fitness, 2006, Volume: 46, Issue:3

    Topics: Adrenocorticotropic Hormone; Adult; Area Under Curve; Biomarkers; Case-Control Studies; Dehydroepian

2006
Endocrine and immune responses to resistance training in prostate cancer patients.
    Prostate cancer and prostatic diseases, 2008, Volume: 11, Issue:2

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Biomarkers; Bone Remodeling;

2008
Effects of dehydroepiandrosterone sulfate on cellular calcium responsiveness and vascular contractility.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:6 Pt 2

    Topics: Analysis of Variance; Animals; Calcium; Cells, Cultured; Cytosol; Dehydroepiandrosterone; Dehydroepi

1995
Deficient insulin-like growth factor I in chronic heart failure predicts altered body composition, anabolic deficiency, cytokine and neurohormonal activation.
    Journal of the American College of Cardiology, 1998, Volume: 32, Issue:2

    Topics: Adrenergic alpha-Agonists; Age Factors; Aged; Anatomy, Cross-Sectional; Body Composition; Body Mass

1998
ET-1 modulates KCa-channel activity and arterial tension in normoxic and hypoxic human pulmonary vasculature.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: 4-Aminopyridine; Analysis of Variance; Cell Hypoxia; Cells, Cultured; Charybdotoxin; Dehydroepiandro

1998
Basal concentrations and acute responses of serum hormones and strength development during heavy resistance training in middle-aged and elderly men and women.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2000, Volume: 55, Issue:2

    Topics: Adult; Age Factors; Aged; Body Mass Index; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; E

2000
Augmentation of the pharmacological action of corydalis tuber by saussurea root in isolated mouse ileum.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2001, Volume: 121, Issue:8

    Topics: Acetylcholine; Animals; Dehydroepiandrosterone; Drug Synergism; Drugs, Chinese Herbal; Ileum; In Vit

2001
Difference between inhibitory actions of papaverine and dehydroepiandrosterone on the isolated guinea-pig ileum.
    Japanese journal of pharmacology, 1975, Volume: 25, Issue:6

    Topics: Acetylcholine; Aminophylline; Animals; Cyanides; Dehydroepiandrosterone; Depression, Chemical; Dose-

1975
The effects of hydraulic resistance strength training in pre-pubertal males.
    Medicine and science in sports and exercise, 1986, Volume: 18, Issue:6

    Topics: Anthropometry; Body Composition; Child; Creatine Kinase; Dehydroepiandrosterone; Elbow; Humans; Knee

1986
[Evaluation of placenta function using DHEA-S tolerance test; comparison with cardiotocography and placental histology].
    Geburtshilfe und Frauenheilkunde, 1970, Volume: 30, Issue:1

    Topics: Adult; Dehydroepiandrosterone; Estriol; Female; Fetal Heart; Heart Rate; Humans; Labor, Obstetric; M

1970
Intravenous prostaglandins E 2 and F 2 and syntocinon for the induction of term labor.
    The Journal of reproductive medicine, 1972, Volume: 9, Issue:6

    Topics: Cesarean Section; Dehydroepiandrosterone; Delivery, Obstetric; Estradiol; Estriol; Estrone; Evaluati

1972
Biochemical and clinical observations a pregnancy with placental sulphatase and other enzyme deficiencies.
    Clinical endocrinology, 1974, Volume: 3, Issue:2

    Topics: 17-Ketosteroids; Adult; Carbon Radioisotopes; Dehydroepiandrosterone; Estradiol; Estrone; Female; Hu

1974