dehydroepiandrosterone has been researched along with Liver Cirrhosis in 21 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diurnal variations of plasma testosterone and urinary excretion rates of testosterone-, androsterone-, aetiocholanolone-, and DHA-glucuronide, as well as DHA-sulphate were measured before and after selective Leydig-cell stimulation (with 3 X 5000 IU human gonadotrophin) in eight patients with alcoholic liver cirrhosis, ten with acute hepatitis and four with haemochromatosis." | 3.65 | [Androgen metabolism and Leydig-cell function in acute and chronic liver disease (author's transl)]. ( Gerdes, H; Littmann, KP; Martini, GA, 1975) |
| "Dehydroepiandrosterone (DHEA) is an abundant steroid and precursor of sex hormones." | 1.91 | DHEA and Its Metabolites Reduce the Cytokines Involved in the Inflammatory Response and Fibrosis in Primary Biliary Cholangitis. ( Blatkiewicz, M; Kilańczyk, E; Piotrowska, K; Sielatycka, K, 2023) |
| "Type 2 diabetes is clinically associated with progressive necroinflammation and fibrosis in nonalcoholic steatohepatitis (NASH)." | 1.56 | AGER1 downregulation associates with fibrosis in nonalcoholic steatohepatitis and type 2 diabetes. ( Ali, M; Charville, GW; Das, S; Dehnad, A; Fan, W; Fish, SR; Jiang, JX; Li, Y; Mozes, G; Olson, KA; Török, NJ; Wong, KA, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (71.43) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 2 (9.52) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 2 (9.52) | 2.80 |
| Authors | Studies |
|---|---|
| Blatkiewicz, M | 1 |
| Sielatycka, K | 1 |
| Piotrowska, K | 1 |
| Kilańczyk, E | 1 |
| Dehnad, A | 1 |
| Fan, W | 1 |
| Jiang, JX | 1 |
| Fish, SR | 1 |
| Li, Y | 1 |
| Das, S | 1 |
| Mozes, G | 1 |
| Wong, KA | 1 |
| Olson, KA | 1 |
| Charville, GW | 1 |
| Ali, M | 1 |
| Török, NJ | 1 |
| Koehler, E | 1 |
| Swain, J | 1 |
| Sanderson, S | 2 |
| Krishnan, A | 2 |
| Watt, K | 1 |
| Charlton, M | 2 |
| FIEGEL, G | 1 |
| KELLING, HW | 1 |
| LOTTI, G | 1 |
| MARCENARO, A | 1 |
| KIM, CY | 1 |
| HYUN, W | 1 |
| PAHK, SK | 1 |
| HAHN, SS | 1 |
| Angulo, P | 1 |
| Chalasani, N | 1 |
| Merriman, R | 1 |
| Viker, K | 1 |
| Charatcharoenwitthaya, P | 1 |
| Gawrieh, S | 1 |
| Lindor, K | 1 |
| Nakamuta, M | 1 |
| Ohashi, M | 1 |
| Goto, K | 1 |
| Tanabe, Y | 1 |
| Hiroshige, K | 1 |
| Nawata, H | 1 |
| Narasaka, T | 1 |
| Moriya, T | 1 |
| Endoh, M | 1 |
| Suzuki, T | 1 |
| Shizawa, S | 1 |
| Mizokami, Y | 1 |
| Matsuoka, T | 1 |
| Sasano, H | 1 |
| Littmann, KP | 2 |
| Gerdes, H | 1 |
| Martini, GA | 1 |
| Ruiz Gonzalez, MC | 1 |
| Martinez Venano, J | 1 |
| Oriol-Bosch, A | 1 |
| Elewaut, A | 1 |
| Barbier, F | 1 |
| Vermeulen, A | 1 |
| Franz, C | 1 |
| Watson, D | 1 |
| Longcope, C | 1 |
| Capra, F | 1 |
| Casaril, M | 1 |
| Stanzial, AM | 1 |
| Gabrielli, GB | 1 |
| Marsilli, R | 1 |
| Ferrari, S | 1 |
| Corrocher, R | 1 |
| Bannister, P | 1 |
| Sheridan, P | 1 |
| Losowsky, MS | 1 |
| Wolff, HP | 1 |
| Kono, T | 2 |
| Yoshimi, T | 2 |
| Osako, F | 1 |
| Oseko, F | 1 |
| Fukase, M | 1 |
| Takahara, J | 1 |
| Hashimoto, K | 1 |
| Ofuji, T | 1 |
| Fassati, P | 1 |
| Fassati, M | 1 |
| Sonka, J | 1 |
| Josifko, M | 1 |
2 reviews available for dehydroepiandrosterone and Liver Cirrhosis
| Article | Year |
|---|---|
[Clinical steroid analysis, using H3 and C14 (determination of their secretion, plasma concentration, secretion rate, as well as metabolism and renal clearance rate)].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Aldosterone; Carbon Isotopes; Chemistry, Clin | 1965 |
[Androgen metabolism in liver diseases].
Topics: Androgens; Androsterone; Carbon Radioisotopes; Dehydroepiandrosterone; Etiocholanolone; Hepatitis; H | 1973 |
1 trial available for dehydroepiandrosterone and Liver Cirrhosis
| Article | Year |
|---|---|
Treatment of stabilized liver cirrhosis by dehydroepiandrosterone sulphate. I. Evaluation of principal biochemical tests as a whole.
Topics: Adult; Alkaline Phosphatase; Cholesterol; Clinical Trials as Topic; Dehydroepiandrosterone; Female; | 1973 |
18 other studies available for dehydroepiandrosterone and Liver Cirrhosis
| Article | Year |
|---|---|
DHEA and Its Metabolites Reduce the Cytokines Involved in the Inflammatory Response and Fibrosis in Primary Biliary Cholangitis.
Topics: Aged; Cytokines; Dehydroepiandrosterone; Female; Fibrosis; Humans; Interleukin-8; Interleukins; Live | 2023 |
AGER1 downregulation associates with fibrosis in nonalcoholic steatohepatitis and type 2 diabetes.
Topics: Animals; Ascorbic Acid; Cholecalciferol; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Disease | 2020 |
Growth hormone, dehydroepiandrosterone and adiponectin levels in non-alcoholic steatohepatitis: an endocrine signature for advanced fibrosis in obese patients.
Topics: Adiponectin; Biomarkers; Dehydroepiandrosterone; Fatty Liver; Female; Growth Hormone; Humans; Liver | 2012 |
[Behavior of nor-androstenolone phenyl propionate in severe liver damage; comparative studies with early results with testosterone propionate].
Topics: Abdominal Injuries; Dehydroepiandrosterone; Liver Cirrhosis; Liver Diseases; Organic Chemicals; Prop | 1959 |
[Chromatographic study of urinary 17-ketosteroids in hepatic cirrhosis. 2. The degradation of dehydroepiandrosterone and testosterone].
Topics: 17-Ketosteroids; Androgens; Chromatography; Dehydroepiandrosterone; Humans; Lipid Metabolism; Liver | 1960 |
[The effects of 19-nor-androstenolone phenylpropionate on the serum protein fractions, hematologic changes, blood urea nitrogen and clinical findings in the cases of liver cirrhosis with ascites, G-I disorders and nephritis].
Topics: Ascites; Blood Protein Electrophoresis; Blood Urea Nitrogen; Dehydroepiandrosterone; Glomerulonephri | 1963 |
Low circulating levels of dehydroepiandrosterone in histologically advanced nonalcoholic fatty liver disease.
Topics: Adiponectin; Adult; Biomarkers; Biopsy; Blood Glucose; C-Reactive Protein; Cohort Studies; Dehydroep | 2008 |
The re-evaluation of sex steroids metabolism in patients with non-alcoholic liver cirrhosis.
Topics: Aged; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Estrone; H | 1994 |
17Beta-hydroxysteroid dehydrogenase type 2 and dehydroepiandrosterone sulfotransferase in the human liver.
Topics: 17-Hydroxysteroid Dehydrogenases; Aged; Carcinoma, Hepatocellular; Cholangiocarcinoma; Dehydroepiand | 2000 |
[Androgen metabolism and Leydig-cell function in acute and chronic liver disease (author's transl)].
Topics: Acute Disease; Adult; Aged; Androgens; Androsterone; Chorionic Gonadotropin; Chronic Disease; Circad | 1975 |
The effect of dehydroepiandrosterone sulfate administration on the 16alpha-hydroxy-dehydroepiandrosterone excretion in cirrhotic patients.
Topics: Adult; Aged; Chromatography, Gas; Dehydroepiandrosterone; Humans; Liver Cirrhosis; Middle Aged | 1976 |
Testosterone metabolism in normal males and male cirrhotics.
Topics: Adipose Tissue; Androstenedione; Dehydroepiandrosterone; Humans; Liver; Liver Cirrhosis; Male; Metab | 1979 |
Estrone sulfate and dehydroepiandrosterone sulfate concentrations in normal subjects and men with cirrhosis.
Topics: Adult; Aged; Dehydroepiandrosterone; Estrogens, Conjugated (USP); Estrone; Female; Humans; Liver Cir | 1979 |
[Plasma dehydroepiandrosterone sulfate and urine steroid excretion in hepatic cirrhosis].
Topics: Adult; Aged; Androstanes; Dehydroepiandrosterone; Female; Humans; Liver Cirrhosis; Male; Middle Aged | 1989 |
Plasma concentrations of sex hormones in postmenopausal women in non-alcoholic cirrhosis.
Topics: Aged; Androstenedione; Dehydroepiandrosterone; Estradiol; Female; Gonadal Steroid Hormones; Humans; | 1985 |
[Metabolism of DHA and DHA sulfate and their interconversion].
Topics: Acute Disease; Adult; Chromatography; Chromatography, Paper; Dehydroepiandrosterone; Female; Hepatit | 1972 |
Kinetics of dehydroepiandrosterone sulphate metabolism in normal controls and pateints with liver cirrhosis and acute hepatitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Chromatography, Paper; Dehydroepiandrosterone; Female; Half- | 1974 |
[Gas liquid chromatography analysis of urinary neutral steroid fractions in normal persons and patients with various diseases].
Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormon | 1970 |