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dehydroepiandrosterone and Leukodystrophy, Metachromatic

dehydroepiandrosterone has been researched along with Leukodystrophy, Metachromatic in 3 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Leukodystrophy, Metachromatic: An autosomal recessive metabolic disease caused by a deficiency of CEREBROSIDE-SULFATASE leading to intralysosomal accumulation of cerebroside sulfate (SULFOGLYCOSPHINGOLIPIDS) in the nervous system and other organs. Pathological features include diffuse demyelination, and metachromatically-staining granules in many cell types such as the GLIAL CELLS. There are several allelic and nonallelic forms with a variety of neurological symptoms.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iwamori, M1
Moser, HW1
Kishimoto, Y1
Eto, Y2
Wiesmann, UN1
Carson, JH1
Herschkowitz, NN2
Rampini, S1
Wiesmann, U1

Other Studies

3 other studies available for dehydroepiandrosterone and Leukodystrophy, Metachromatic

ArticleYear
Steroid sulfatase in brain: comparison of sulfohydrolase activities for various steroid sulfates in normal and pathological brains, including the various forms of metachromatic leukodystrophy.
    Journal of neurochemistry, 1976, Volume: 27, Issue:6

    Topics: Aging; Animals; Arylsulfatases; Brain; Cholesterol; Dehydroepiandrosterone; Detergents; Estrone; Fem

1976
Multiple sulfatase deficiencies in cultured skin fibroblasts. Occurrence in patients with a variant form of metachromatic leukodystrophy.
    Archives of neurology, 1974, Volume: 30, Issue:2

    Topics: Adult; Cholesterol; Dehydroepiandrosterone; Fibroblasts; Galactosidases; Glycosaminoglycans; Hexosam

1974
Enzymic studies of sulphatases in tissues of the normal human and in metachromatic leukodystrophy with multiple sulphatase deficiencies: arylsulphatases A, B and C, cerebroside sulphatase, psychosine sulphatase and steroid sulphatases.
    Journal of neurochemistry, 1974, Volume: 23, Issue:6

    Topics: Adult; Brain; Cerebrosides; Child; Child, Preschool; Cholesterol; Chromatography, Thin Layer; Coumar

1974