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dehydroepiandrosterone and Interstitial Cell Tumor

dehydroepiandrosterone has been researched along with Interstitial Cell Tumor in 28 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
"A plasma testosterone/androstenedione (T/A) ratio was calculated in 15 women with possible ovarian neoplasms and androgen excess and whose mean plasma concentration of testosterone approached or was greater than a twofold elevation."3.66Testosterone/androstenedione ratio in the evaluation of women with ovarian androgen excess. ( Morris, CV; Wiebe, RH, 1983)
"After surgery, the boy entered true precocious puberty."1.37Clinical and metabolic findings in a 6-year-old boy with a Leydig cell tumour. ( Hartmann, MF; Lignitz, S; Partsch, CJ; Pohlenz, J; Wudy, SA, 2011)
"Testicular tumors are very rare in boys, approximately 1."1.31[Precocious puberty caused by a testicular Leydig cell tumor]. ( Borbás, E; Minik, K; Réti, G; Ságodi, L; Sólyom, E, 2001)
"The incidence of spontaneous Leydig cell tumors of testis is very high in old F-344 rats."1.28Inhibition of spontaneous testicular Leydig cell tumor development in F-344 rats by dehydroepiandrosterone. ( Rao, MS; Reddy, JK; Subbarao, V; Yeldandi, AV, 1992)
"We present an unusual patient with a Leydig cell tumor to show that greatly elevated serum concentrations of 17-hydroxyprogesterone (17OHP) may not be diagnostic of congenital adrenal hyperplasia (CAH)."1.28Molecular characterization of a Leydig cell tumor presenting as congenital adrenal hyperplasia. ( Goldsmith, MA; Miller, WL; Solish, SB; Voutilainen, R, 1989)
"Dehydroepiandrosterone sulfate and estrone were moderately increased, while LH, FSH, and estradiol were minimally increased."1.2617 beta-hydroxysteroid dehydrogenase deficiency in malignant interstitial cell carcinoma of the testis. ( Davis, S; DiMartino, NA; Schneider, G, 1980)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199024 (85.71)18.7374
1990's2 (7.14)18.2507
2000's1 (3.57)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lignitz, S1
Partsch, CJ1
Wudy, SA1
Hartmann, MF1
Pohlenz, J1
GUAL, C1
SANCHEZ, J1
DORFMAN, RI1
ROSENTHAL, IM1
Wiebe, RH1
Morris, CV1
Davis, S1
DiMartino, NA1
Schneider, G2
Baiocchi, G1
Manci, N1
Angeletti, G1
Celleno, R1
Fratini, D1
Gilardi, G1
Ságodi, L1
Borbás, E1
Réti, G1
Minik, K1
Sólyom, E1
Demisch, K1
Magnet, W1
Neubauer, M1
Schöffling, K1
Soules, MR1
Abraham, GE1
Bossen, EH1
Rao, MS1
Subbarao, V1
Yeldandi, AV1
Reddy, JK1
Haning, RV1
Loughlin, J1
Shapiro, SS1
Nagamani, M1
Stuart, CA1
Van Dinh, T1
Solish, SB1
Goldsmith, MA1
Voutilainen, R1
Miller, WL1
Urdl, W1
Lammer, H1
Tscherne, G1
Pickel, H1
Haruyama, Y1
Miyakawa, I1
Inoue, H1
Mori, N1
Pierrepoint, CG1
Griffiths, K1
Grant, JK1
Stewart, JS1
Rippmann, ET1
Gloor, F1
Keller, M1
Lucis, OJ1
Lucis, R1
Yoshida, Y1
Mori, T1
Nishimura, T1
Kono, T1
Yamada, S1
Tatsumi, S1
Vanha-Perttula, T1
Bardin, CW1
Stanley, AJ1
Gumbreck, LG1
Allison, JE1
Ances, IG1
Connor, TB1
Gallaher, EP1
Migeon, CJ1
Levin, HS1
Ganis, FM1
Root, A1
Steinberger, E1
Smith, K1
Steinberger, A1
Russ, D1
Somers, L1
Rosenfield, R1
Jull, JW1
McClellan, D1
Coupey, S1
Richards, G1
Neville, AM1
Judd, HL1
Spore, WW1
Talner, LB1
Rigg, LA1
Yen, SS1
Benirschke, K1
Roth, LM1
Cleary, RE1
Rosenfield, RL1
Wegienka, LC1
Kolb, FO1
Lehmann, WD1
Lauritzen, C1
Kalderon, AE1
Tucci, JR1

Reviews

1 review available for dehydroepiandrosterone and Interstitial Cell Tumor

ArticleYear
Diagnosis and resection of an oral contraceptive-suppressible Sertoli-Leydig cell tumor with preservation of fertility and a 7-year follow-up.
    Obstetrics and gynecology, 1989, Volume: 73, Issue:5 Pt 2

    Topics: Adult; Contraceptives, Oral; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Fertili

1989

Other Studies

27 other studies available for dehydroepiandrosterone and Interstitial Cell Tumor

ArticleYear
Clinical and metabolic findings in a 6-year-old boy with a Leydig cell tumour.
    Acta paediatrica (Oslo, Norway : 1992), 2011, Volume: 100, Issue:12

    Topics: Androsterone; Antineoplastic Agents, Hormonal; Child; Dehydroepiandrosterone; Etiocholanolone; Human

2011
Androgen biosynthesis in an interstitial cell tumor of the testis.
    The Journal of clinical endocrinology and metabolism, 1962, Volume: 22

    Topics: Anatomy; Dehydroepiandrosterone; Humans; Leydig Cell Tumor; Male; Testosterone

1962
Testosterone/androstenedione ratio in the evaluation of women with ovarian androgen excess.
    Obstetrics and gynecology, 1983, Volume: 61, Issue:3

    Topics: Adolescent; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female;

1983
17 beta-hydroxysteroid dehydrogenase deficiency in malignant interstitial cell carcinoma of the testis.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:6

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstenedione; Carcinoma; Chorionic Gonadotropin; Dehydroepiandr

1980
Pure Leydig cell tumour (hilus cell) of the ovary: a rare cause of virilization after menopause.
    Gynecologic and obstetric investigation, 1997, Volume: 44, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Androgens; Androstenedione; Androsterone;

1997
[Precocious puberty caused by a testicular Leydig cell tumor].
    Orvosi hetilap, 2001, Jan-28, Volume: 142, Issue:4

    Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Child, Preschool; Dehydroepiandrostero

2001
[Androgens in the plasma of women with hirsutism (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1975, May-16, Volume: 100, Issue:20

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Androgens; Androstenediols; Carcinoma; Dehydroe

1975
The steroid profile of a virilizing ovarian tumor.
    Obstetrics and gynecology, 1978, Volume: 52, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; F

1978
Inhibition of spontaneous testicular Leydig cell tumor development in F-344 rats by dehydroepiandrosterone.
    Cancer letters, 1992, Aug-14, Volume: 65, Issue:2

    Topics: Aging; Animals; Antineoplastic Agents; Dehydroepiandrosterone; Diet; Hyperplasia; Leydig Cell Tumor;

1992
Steroid biosynthesis in the Sertoli-Leydig cell tumor: effects of insulin and luteinizing hormone.
    American journal of obstetrics and gynecology, 1989, Volume: 161, Issue:6 Pt 1

    Topics: Adult; Androstenedione; Cells, Cultured; Dehydroepiandrosterone; Female; Humans; Insulin; Leydig Cel

1989
Molecular characterization of a Leydig cell tumor presenting as congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 69, Issue:6

    Topics: 17-alpha-Hydroxyprogesterone; 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocorticotropic

1989
[Selective venous catheterization in the evaluation of androgenism].
    Wiener klinische Wochenschrift, 1986, May-30, Volume: 98, Issue:11

    Topics: Adult; Catheterization; Dehydroepiandrosterone; Estradiol; Female; Hirsutism; Humans; Leydig Cell Tu

1986
[Endocrinological study of Sertoli-Leydig cell tumor].
    Nihon Sanka Fujinka Gakkai zasshi, 1987, Volume: 39, Issue:5

    Topics: 17-Ketosteroids; Adult; Androstenedione; Chorionic Gonadotropin; Dehydroepiandrosterone; Dexamethaso

1987
Neutral steroid sulphation and oestrogen biosynthesis in vitro by a feminizing Leydig cell tumour of the testis.
    The Journal of endocrinology, 1966, Volume: 35, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; Adult; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol;

1966
[Hilus cell tumor of the ovary].
    Gynaecologia. International monthly review of obstetrics and gynecology. Revue internationale mensuelle d'obstetrique et de gynecologie. Monatsschrift fur Geburtshilfe und Gynakologie, 1968, Volume: 166, Issue:5

    Topics: 17-Ketosteroids; Adult; Androsterone; Cesarean Section; Dehydroepiandrosterone; Female; Humans; Leyd

1968
Conversion of dehydroepiandrosterone, pregnenolone, and progesterone by interstitial cell tumor tissue.
    Cancer research, 1970, Volume: 30, Issue:3

    Topics: Androstanes; Animals; Carbon Isotopes; Chromatography; Corticosterone; Dehydroepiandrosterone; Desox

1970
Clinical and biochemical studies of a patient with a hilus cell tumour.
    The Journal of endocrinology, 1970, Volume: 47, Issue:1

    Topics: 17-Ketosteroids; Adult; Amenorrhea; Androgens; Blood Cell Count; Dehydroepiandrosterone; Dexamethaso

1970
Testicular tumors in the androgen insensitive pseudohermaphrodite rat: histochemistry and steroid metabolism.
    Gynecologic investigation, 1970, Volume: 1, Issue:3

    Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Disease Models, Animal

1970
Case of feminizing interstitial cell tumor of the testicle. Clinical and biochemical evaluation.
    The Journal of clinical endocrinology and metabolism, 1971, Volume: 33, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Androgen-Insensitivity Syndrome; Androstanes; Chr

1971
Isosexual pseudoprecocity in a 6-year-old boy with a testicular interstitial cell adenoma.
    The Journal of pediatrics, 1972, Volume: 80, Issue:2

    Topics: 17-Ketosteroids; Androstanes; Child; Chorionic Gonadotropin; Dehydroepiandrosterone; Humans; Hydroco

1972
Steroid metabolism by an oestrogen-dependent interstitial-cell tumour of a rat testis.
    The Journal of endocrinology, 1973, Volume: 59, Issue:1

    Topics: Androstenedione; Androstenes; Androsterone; Animals; Carbon Radioisotopes; Cholesterol; Chromatograp

1973
Steroid metabolism in vitro by an interstitial cell tumour and the attached prepubertal testis.
    The Journal of endocrinology, 1973, Volume: 59, Issue:3

    Topics: Adolescent; Androstenedione; Carbon Radioisotopes; Chromatography, Thin Layer; Dehydroepiandrosteron

1973
Preoperative localization of a testosterone-secreting ovarian tumor by retrograde venous catheterization and selective sampling.
    American journal of obstetrics and gynecology, 1974, Volume: 120, Issue:1

    Topics: 17-Ketosteroids; Adrenal Glands; Adult; Androstenedione; Catheterization; Chorionic Gonadotropin; De

1974
Sertoli-Leydig cell tumor of the ovary, with an associated mucinous cystadenoma. An ultrastructural and endocrine study.
    Laboratory investigation; a journal of technical methods and pathology, 1974, Volume: 31, Issue:6

    Topics: Adolescent; Androstenediols; Androstenedione; Cystadenoma; Dehydroepiandrosterone; Dexamethasone; Fe

1974
Hormonal studies of a benign interstitial cell tumour of the testis producing androstenedione and testosterone.
    Acta endocrinologica, 1967, Volume: 56, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Androgens; Dehy

1967
[Combined dexamethasone suppression and chorionic gonadotrophin stimulation test in the diagnosis of androgenic functional ovarian tumors].
    Geburtshilfe und Frauenheilkunde, 1972, Volume: 32, Issue:11

    Topics: 17-Ketosteroids; Adenocarcinoma; Adult; Androgens; Chorionic Gonadotropin; Dehydroepiandrosterone; D

1972
Ultrastructure of a human chorionic gonadotropin-and adrenocorticotropin-responsive functioning Sertoli-Leydig cell tumor (type I).
    Laboratory investigation; a journal of technical methods and pathology, 1973, Volume: 29, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Androsterone; Chorio

1973