Page last updated: 2024-11-07

dehydroepiandrosterone and Intellectual Disability

dehydroepiandrosterone has been researched along with Intellectual Disability in 6 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
REISS, M1
HILLMAN, J1
DAVIS, RH1
HAMILTON, JB1
BUNCH, LD1
MESTLER, GE1
IMAGAWA, R1
Patel, BN1
Pang, D1
Stern, Y1
Silverman, W1
Kline, JK1
Mayeux, R1
Schupf, N1
Tordjman, S1
Anderson, GM1
McBride, PA1
Hertzig, ME1
Snow, ME1
Hall, LM1
Ferrari, P1
Cohen, DJ1
de Moor, P1
Heyns, W1
Steeno, O1
Scott, JR1
Yannone, ME1
Zellweger, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multi-center, Prospective, Cohort Study to Elucidate the Effects of Metformin Treatment on Steroid Hormones and Social Behavior. Linking Autistic Behaviorial Symptoms to Changes in Steroid Hormone Availability[NCT04930471]45 participants (Anticipated)Observational2021-06-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for dehydroepiandrosterone and Intellectual Disability

ArticleYear
Effect of prolonged treatment with human chorionic gonadotropin on the endogenous steroid hormone metabolism of physically and mentally retarded boys.
    The Journal of clinical endocrinology and metabolism, 1963, Volume: 23

    Topics: 17-Ketosteroids; Anatomy; Androsterone; Chorionic Gonadotropin; Dehydroepiandrosterone; Genitalia; G

1963
EFFECT OF CASTRATION IN MAN UPON BLOOD SEDIMENTATION RATE, HEMATOCRIT AND HEMOGLOBIN.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Aging; Androsterone; Biomedical Research; Bl

1964
Obesity enhances verbal memory in postmenopausal women with Down syndrome.
    Neurobiology of aging, 2004, Volume: 25, Issue:2

    Topics: Adult; Body Mass Index; Case-Control Studies; Dehydroepiandrosterone; Depression; Down Syndrome; Est

2004
Plasma androgens in autism.
    Journal of autism and developmental disorders, 1995, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Autistic Disorder; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepiand

1995
Clinical and biochemical features associated with extreme CBC-values; possible significance of these associations.
    Annales d'endocrinologie, 1968, Volume: 29

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Androsterone; Blood Protein

1968
Plasma androgen and cytogenetic studies of a patient with Morgagni's syndrome.
    The Journal of reproductive medicine, 1971, Volume: 6, Issue:4

    Topics: Adult; Androgens; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hyperostosis Frontalis Interna;

1971