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dehydroepiandrosterone and Hypospadias

dehydroepiandrosterone has been researched along with Hypospadias in 11 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Hypospadias: A birth defect due to malformation of the URETHRA in which the urethral opening is below its normal location. In the male, the malformed urethra generally opens on the ventral surface of the PENIS or on the PERINEUM. In the female, the malformed urethral opening is in the VAGINA.

Research Excerpts

ExcerptRelevanceReference
"Serum levels of testosterone, androstenedione and dehydroepiandrosterone were measured before and after 5 days of treatment with hCG (2000 IU/d) in 36 prepubertal boys with cryptorchidism and 11 with hypospadias in order to determine whether a defect in androgen synthesis could be a common cause for these disorders."3.65Plasma androgen responce to hCG stimulation in prepubertal boys with hypospadias and cryptorchidism. ( Curry, N; Mills, RC; Siiteri, PK; Walsh, PC, 1976)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balkan, M1
Duran, H1
Onen, A1
Oral, D1
Isi, H1
Fidanboy, M1
Alp, MN1
Budak, T1
GOLDMAN, AS1
BONGIOVANNI, AM2
YAKOVAC, WC1
PRADER, A1
Briggs, MH1
Berg, R1
Berg, G1
Edman, G1
Svensson, J1
Aström, G1
Walsh, PC1
Curry, N1
Mills, RC1
Siiteri, PK1
Glatzl, J1
Carpenter, TO1
Imperato-McGinley, J1
Boulware, SD1
Weiss, RM1
Shackleton, C1
Griffin, JE1
Wilson, JD1
Bals-Pratsch, M1
Schweikert, HU1
Nieschlag, E1
Cara, JF1
Moshang, T1
Marx, BS1
Bloch, E1
Lew, M1
Klein, M1
Garmendia, F1
Nicolis, GL1
Gabrilove, JL1

Other Studies

11 other studies available for dehydroepiandrosterone and Hypospadias

ArticleYear
Cytogenetic and clinical studies of a male infant with disorder of sexual development: case report.
    Fertility and sterility, 2008, Volume: 90, Issue:5

    Topics: Chromosome Banding; Chromosome Painting; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 4; Deh

2008
STUDY OF DELTA-5, 3-BETA-HYDROXYSTEROID DEHYDROGENASE IN NORMAL, HYPERPLASTIC AND NEOPLASTIC ADRENAL CORTICAL TISSUE.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; 3-Hydroxysteroid Dehydrogenases; Adrenal Gland Diseases;

1964
Hypospadias, androgen biosynthesis, and synthetic progestogens during pregnancy.
    International journal of fertility, 1982, Volume: 27, Issue:2

    Topics: Androgens; Animals; Dehydroepiandrosterone; Female; Fetus; Hypospadias; Pregnancy; Progesterone Cong

1982
Androgens and personality in normal men and men operated for hypospadias in childhood.
    Acta psychiatrica Scandinavica, 1983, Volume: 68, Issue:3

    Topics: Adult; Androgens; Child; Child, Preschool; Dehydroepiandrosterone; Follicle Stimulating Hormone; Fol

1983
Plasma androgen responce to hCG stimulation in prepubertal boys with hypospadias and cryptorchidism.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 42, Issue:1

    Topics: Adolescent; Androgens; Androstenedione; Child; Child, Preschool; Chorionic Gonadotropin; Cryptorchid

1976
[Hypospadias in infancy I) pathophysiologic considerations II) hormonal balance studies (author's transl)].
    Padiatrie und Padologie, 1975, Volume: 10, Issue:4

    Topics: Androgens; Androsterone; Dehydroepiandrosterone; Female; Genitalia; Humans; Hydroxysteroids; Hypospa

1975
Variable expression of 5 alpha-reductase deficiency: presentation with male phenotype in a child of Greek origin.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 71, Issue:2

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Androstenedione; Biopsy; Chorionic Gonadotropin; Dehyd

1990
Androgen receptor disorder in three brothers with bifid prepenile scrotum and hypospadias.
    Acta endocrinologica, 1990, Volume: 123, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adult; Androstenedione; Chorionic Gonadotropin; Dehydroepiandrosterone

1990
Elevated 17-hydroxyprogesterone and testosterone in a newborn with 3-beta-hydroxysteroid dehydrogenase deficiency.
    The New England journal of medicine, 1985, Sep-05, Volume: 313, Issue:10

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 20-Hydroxysteroid Dehydrogenases; Adrena

1985
Studies on the inhibition of fetal androgen formation. Inhibition of testosterone synthesis in rat and rabbit fetal testes with observations on reproductive tract development.
    Endocrinology, 1971, Volume: 89, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Abnormalities, Drug-Induced; Androstanes; Animals; Ca

1971
The determination of urinary pregnanetriol and the neutral 17-ketosteroids by gas-liquid chromatography.
    Steroids, 1971, Volume: 18, Issue:2

    Topics: 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adre

1971