Page last updated: 2024-11-07

dehydroepiandrosterone and Hypomenorrhea

dehydroepiandrosterone has been researched along with Hypomenorrhea in 30 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
"The effects of epimestrol (5 mg every 6 hours for 5 days) on basal levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (Prl), estradiol, progesterone, and dehydroepiandrosterone sulfate, and on the response to LH-releasing hormone (LH-RH) and thyrotropin-releasing hormone (TRH) stimulation, were studied in 18 cases of secondary amenorrhea and oligomenorrhea of hypothalamic-pituitary origin, in three cases of anorexia nervosa, in two cases of long-lasting progestin-induced amenorrhea, and in one case of precocious menopause."7.66Effect of epimestrol on gonadotropin and prolactin plasma levels and response to luteinizing hormone-releasing hormone/thyrotropin-releasing hormone in secondary amenorrhea and oligomenorrhea. ( de Leo, V; Facchinetti, F; Franchi, F; Genazzani, AR; Kicovic, PM; Parrini, D; Picciolini, E, 1978)
"Serum dehydroepiandrosterone sulfate (DHEAS) was measured in 32 infertility patients who were found to be ovulatory, in 37 women with oligomenorrhea, and in 52 hirsute patients under basal conditions."3.66Serum levels of DHEAS in gynecologic endocrinopathy and infertility. ( Goebelsmann, U; Lobo, RA; Paul, WL, 1981)
"The effects of epimestrol (5 mg every 6 hours for 5 days) on basal levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (Prl), estradiol, progesterone, and dehydroepiandrosterone sulfate, and on the response to LH-releasing hormone (LH-RH) and thyrotropin-releasing hormone (TRH) stimulation, were studied in 18 cases of secondary amenorrhea and oligomenorrhea of hypothalamic-pituitary origin, in three cases of anorexia nervosa, in two cases of long-lasting progestin-induced amenorrhea, and in one case of precocious menopause."3.66Effect of epimestrol on gonadotropin and prolactin plasma levels and response to luteinizing hormone-releasing hormone/thyrotropin-releasing hormone in secondary amenorrhea and oligomenorrhea. ( de Leo, V; Facchinetti, F; Franchi, F; Genazzani, AR; Kicovic, PM; Parrini, D; Picciolini, E, 1978)
"In order to ascertain the usefulness of urinary 17-ketosteroids (17-KS) in the evaluation of hirsutism, 28 paired determinations of 17-KS and serum androgens were performed in 26 hirsute women before (control) and after (post Dex) 7 days of dexamethasone (Dex) administration."3.65Comparison between urinary 17-ketosteroids and serum androgens in hirsute patients. ( Abraham, GE; Manlimos, FS; Maroulis, GB, 1977)
"Eighty-two percent of swimmers had menstrual irregularities after M compared to 40% of control, with longer duration of these irregularities (16 vs."1.29Menstrual dysfunction in swimmers: a distinct entity. ( Constantini, NW; Warren, MP, 1995)
"Polycystic ovarian syndrome and hypogonadotropic hypogonadism occurred significantly more often in women with TLE than in the general female population."1.27Reproductive endocrine disorders in women with partial seizures of temporal lobe origin. ( Geschwind, N; Herzog, AG; Schomer, DL; Seibel, MM; Vaitukaitis, JL, 1986)
"Dehydroepiandrosterone-sulfate was the only steroid which showed significantly different mean levels between the two groups of hirsute women, being higher in the H-OA patients."1.25Ovarian and adrenal contributions to peripheral androgens in hirsute women. ( Abraham, GE; Buster, JE; Chakmakjian, ZH; Marshall, JR, 1975)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199022 (73.33)18.7374
1990's4 (13.33)18.2507
2000's2 (6.67)29.6817
2010's2 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shayya, R1
Chang, RJ2
Iwaoka, Y1
Hashimoto, R1
Koizumi, H1
Yu, J1
Okabe, T1
MARENZI, A1
NOGUES, AE1
MENDIZABAL, A1
BRAEGGER, E1
GIUSTI, G1
TOCCAFONDI, R1
BORGHI, A1
ZURLI, A1
ANZALONE, M1
PERILLO, AE1
GARCIA DE DE LA VILLA, A1
Naessén, S1
Carlström, K1
Garoff, L1
Glant, R1
Hirschberg, AL1
Wu, CH1
Lobo, RA2
Granger, LR1
Davajan, V1
Mishell, DR1
Geisthövel, F1
Skubsch, U1
Zabel, G1
Schillinger, H1
Breckwoldt, M1
Lucky, AW1
McGuire, J1
Rosenfield, RL1
Lucky, PA1
Rich, BH1
Held, BL1
Nader, S1
Rodriguez-Rigau, LJ1
Smith, KD1
Steinberger, E1
Siegberg, R1
Nilsson, CG1
Stenman, UH1
Widholm, O1
Paul, WL1
Goebelsmann, U1
Maroulis, GB3
Constantini, NW1
Warren, MP1
Stephen, LJ1
Kwan, P1
Shapiro, D1
Dominiczak, M1
Brodie, MJ1
Abraham, GE3
Chakmakjian, ZH1
Buster, JE2
Marshall, JR2
Manlimos, FS1
Genazzani, AR1
Facchinetti, F1
de Leo, V1
Picciolini, E1
Franchi, F1
Parrini, D1
Kicovic, PM1
Lamberts, SW1
Koper, JW1
Biemond, P1
den Holder, FH1
de Jong, FH1
Krsnjavi, H1
Milković-Kraus, S1
Prpić-Majić, D1
Redmond, GP1
Bergfeld, W1
Gupta, M1
Bedocs, NM1
Skibinski, C1
Gidwani, G1
Weise, HC1
Moltz, L1
Bispink, G1
Leidenberger, F1
Herzog, AG1
Seibel, MM1
Schomer, DL1
Vaitukaitis, JL2
Geschwind, N1
Chihal, HJ1
Baudier, MM1
Melby, JC1
Bonilla, F1
Scott, JR1
Yannone, ME1
Zellweger, H1
Miasnikov, LA1
Vinogradova, DA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Vitamin D With and Without Hormonal Contraception on Sexual Function in Women With Polycystic Ovary Syndrome[NCT02865187]47 participants (Actual)Interventional2017-02-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Prevalence of Sexual Dysfunction in Women With PCOS

Prevalence rate of women with PCOS defined by scores of the FSFI (total scores range from 2-36; scores less than 26.55 represent presence/degree of sexual dysfunction) - For this outcome, total scores were converted, using the cutoff score of 26.55, into a dichotomous variable for presence or absence of sexual dysfunction. (NCT02865187)
Timeframe: Baseline

InterventionParticipants (Count of Participants)
Vitamin D + Hormonal Contraception26
Vit D + Non-hormonal Contraception11

Sexual Function

Female Sexual Function Index (FSFI) scores at Month 6 (Total score ranges from 2 - 36; scores less than 26.55 represent presence/degree of sexual dysfunction) (NCT02865187)
Timeframe: Month 6

Interventionscore on a scale (Mean)
Vitamin D + Hormonal Contraception24.8
Vit D + Non-hormonal Contraception26.0

Reviews

2 reviews available for dehydroepiandrosterone and Hypomenorrhea

ArticleYear
Reproductive endocrinology of adolescent polycystic ovary syndrome.
    BJOG : an international journal of obstetrics and gynaecology, 2010, Volume: 117, Issue:2

    Topics: Adolescent; Adult; Androgens; Anovulation; Anti-Mullerian Hormone; Child; Dehydroepiandrosterone; Fe

2010
Evaluation of hirsutism and hyperandrogenemia.
    Fertility and sterility, 1981, Volume: 36, Issue:3

    Topics: Adrenal Gland Diseases; Androgens; Androstenediol; Androstenedione; Dehydroepiandrosterone; Dehydroe

1981

Other Studies

28 other studies available for dehydroepiandrosterone and Hypomenorrhea

ArticleYear
Selective stimulation by cinnamaldehyde of progesterone secretion in human adrenal cells.
    Life sciences, 2010, Jun-05, Volume: 86, Issue:23-24

    Topics: Acrolein; Adrenal Glands; Cyclic AMP; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Fema

2010
[Determination of 17-ketosteroids measured in dehydroisoandrosterone units in menstruation disorders].
    La Semana medica, 1953, Aug-06, Volume: 103, Issue:6

    Topics: 17-Ketosteroids; Biological Assay; Body Fluids; Dehydroepiandrosterone; Female; Humans; Menstruation

1953
[STUDIES OF SO-CALLED "SIMPLE" HIRSUTISM. VI. HORMONAL RESEARCH IN DYNAMIC CONDITIONS: REDUCTION WITH DEXAMETHASONE].
    Rassegna di neurologia vegetativa, 1963, Jun-30, Volume: 17

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Dehydroepiandros

1963
[Substance H3 and dehydroisoandrosterone in psychiatry].
    La Semana medica, 1962, Mar-08, Volume: 120

    Topics: Androgens; Biological Assay; Dehydroepiandrosterone; Female; Hormone Replacement Therapy; Humans; Me

1962
Polycystic ovary syndrome in bulimic women--an evaluation based on the new diagnostic criteria.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2006, Volume: 22, Issue:7

    Topics: Adult; Bulimia; Case-Control Studies; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone;

2006
A practical dexamethasone suppression test to evaluate hirsute women.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1982, Volume: 20, Issue:1

    Topics: Adrenal Gland Diseases; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Femal

1982
An extended regimen of clomiphene citrate in women unresponsive to standard therapy.
    Fertility and sterility, 1982, Volume: 37, Issue:6

    Topics: Chorionic Gonadotropin; Clomiphene; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradio

1982
Ultrasonographic and hormonal studies in physiologic and insufficient menstrual cycles.
    Fertility and sterility, 1983, Volume: 39, Issue:3

    Topics: Adult; Corpus Luteum; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Hum

1983
Plasma androgens in women with acne vulgaris.
    The Journal of investigative dermatology, 1983, Volume: 81, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Acne Vulgaris; Adolescent; Adult; Androg

1983
Acne and hyperandrogenism.
    Journal of the American Academy of Dermatology, 1984, Volume: 10, Issue:2 Pt 1

    Topics: Acne Vulgaris; Adolescent; Adult; Analysis of Variance; Dehydroepiandrosterone; Dehydroepiandrostero

1984
Sex hormone profiles in oligomenorrheic adolescent girls and the effect of oral contraceptives.
    Fertility and sterility, 1984, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Androstenedione; Contraceptives, Oral; Contraceptives, Oral, Combined; Dehydroepi

1984
Serum levels of DHEAS in gynecologic endocrinopathy and infertility.
    Obstetrics and gynecology, 1981, Volume: 57, Issue:5

    Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Androstenedione; Dehydroepiandrosterone; Dehydroepiand

1981
Menstrual dysfunction in swimmers: a distinct entity.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:9

    Topics: Adolescent; Androstenedione; Child; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female;

1995
Hormone profiles in young adults with epilepsy treated with sodium valproate or lamotrigine monotherapy.
    Epilepsia, 2001, Volume: 42, Issue:8

    Topics: Adult; Anticonvulsants; Blood Glucose; Body Mass Index; Comorbidity; Dehydroepiandrosterone; Epileps

2001
Ovarian and adrenal contributions to peripheral androgens in hirsute women.
    Obstetrics and gynecology, 1975, Volume: 46, Issue:2

    Topics: Adrenal Glands; Adult; Amenorrhea; Androgens; Androstenedione; Chorionic Gonadotropin; Dehydroepiand

1975
Effect of dexamethasone on serum cortisol and androgen levels in hirsute patients.
    Obstetrics and gynecology, 1976, Volume: 47, Issue:4

    Topics: Adolescent; Adrenal Glands; Adult; Androstenedione; Dehydroepiandrosterone; Dexamethasone; Dihydrote

1976
Comparison between urinary 17-ketosteroids and serum androgens in hirsute patients.
    Obstetrics and gynecology, 1977, Volume: 49, Issue:4

    Topics: 17-Ketosteroids; Adolescent; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Dexamethason

1977
Effect of epimestrol on gonadotropin and prolactin plasma levels and response to luteinizing hormone-releasing hormone/thyrotropin-releasing hormone in secondary amenorrhea and oligomenorrhea.
    Fertility and sterility, 1978, Volume: 30, Issue:6

    Topics: Adolescent; Adult; Amenorrhea; Anorexia Nervosa; Dehydroepiandrosterone; Epimestrol; Estradiol; Estr

1978
Cortisol receptor resistance: the variability of its clinical presentation and response to treatment.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 74, Issue:2

    Topics: Acne Vulgaris; Adrenal Cortex Diseases; Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone;

1992
Acute intermittent porphyria and hormone disbalance.
    Medical hypotheses, 1991, Volume: 34, Issue:2

    Topics: Adult; Anovulation; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Folli

1991
Menstrual dysfunction in hirsute women.
    Journal of the American Academy of Dermatology, 1990, Volume: 22, Issue:1

    Topics: Adult; Androstenedione; Body Weight; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female;

1990
[Rational hormonal diagnosis of oligomenorrhea].
    Geburtshilfe und Frauenheilkunde, 1989, Volume: 49, Issue:8

    Topics: Adolescent; Adult; Amenorrhea; Body Weight; Dehydroepiandrosterone; Diagnosis, Differential; Female;

1989
Reproductive endocrine disorders in women with partial seizures of temporal lobe origin.
    Archives of neurology, 1986, Volume: 43, Issue:4

    Topics: Adult; Dehydroepiandrosterone; Endocrine System Diseases; Epilepsy, Temporal Lobe; Estradiol; Female

1986
Polycystic ovary syndrome.
    American family physician, 1985, Volume: 31, Issue:4

    Topics: Androgens; Clomiphene; Contraceptives, Oral; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate;

1985
Menstrual disorders associated with adrenal dysfunction.
    Clinical obstetrics and gynecology, 1969, Volume: 12, Issue:3

    Topics: 17-Ketosteroids; Addison Disease; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands;

1969
[Endocrine analysis in female sterility].
    Acta obstetrica y ginecologica hispano-lusitana, 1970, Volume: 18, Issue:3

    Topics: 17-Ketosteroids; Dehydroepiandrosterone; Endocrine Glands; Endocrine System Diseases; Endometrium; F

1970
Plasma androgen and cytogenetic studies of a patient with Morgagni's syndrome.
    The Journal of reproductive medicine, 1971, Volume: 6, Issue:4

    Topics: Adult; Androgens; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hyperostosis Frontalis Interna;

1971
[Estrogens and androgens in dyshormonal cardiopathy and coronary atherosclerosis in women].
    Kardiologiia, 1971, Volume: 11, Issue:9

    Topics: 17-Ketosteroids; Adult; Androgens; Androsterone; Arteriosclerosis; Chromatography, Thin Layer; Coron

1971