dehydroepiandrosterone has been researched along with Hypogonadism in 71 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Hypogonadism: Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).
Excerpt | Relevance | Reference |
---|---|---|
"The endocrine system of aging males reveals changes of more or less unknown significance for estrogens, dehydroepiandrosterone (DHEA), melatonin and growth hormone." | 8.82 | [Hormone therapy in the aging male. Estrogen, DHEA, melatonin, somatotropin]. ( Kliesch, S, 2004) |
"It has previously been shown that increased nocturnal melatonin (MT) secretion exists in male patients with hypogonadotropic hypogonadism." | 7.69 | Daytime plasma melatonin levels in male hypogonadism. ( Beyhan, Z; Bingol, N; Bolu, E; Bulur, M; Corakci, A; Gundogan, MA; Ozata, M, 1996) |
"The purpose of this study was to evaluate, without using radioisotopes, the peripheral contribution of dehydroepiandrosterone (D) to estrogens and to androstenedione (A) in patients with hypogonadotropic hypogonadism associated with weight loss (HH) and in normal menstruating women (N)." | 7.67 | Reduced conversion of dehydroepiandrosterone into estrogens in women having hypogonadotropic hypogonadism associated with weight loss. ( Bolelli, G; Bonavia, M; Bulletti, C; Ferraretti, AP; Flamigni, C; Franceschetti, F; Jasonni, VM, 1986) |
"The endocrine system of aging males reveals changes of more or less unknown significance for estrogens, dehydroepiandrosterone (DHEA), melatonin and growth hormone." | 4.82 | [Hormone therapy in the aging male. Estrogen, DHEA, melatonin, somatotropin]. ( Kliesch, S, 2004) |
"It has previously been shown that increased nocturnal melatonin (MT) secretion exists in male patients with hypogonadotropic hypogonadism." | 3.69 | Daytime plasma melatonin levels in male hypogonadism. ( Beyhan, Z; Bingol, N; Bolu, E; Bulur, M; Corakci, A; Gundogan, MA; Ozata, M, 1996) |
"The purpose of this study was to evaluate, without using radioisotopes, the peripheral contribution of dehydroepiandrosterone (D) to estrogens and to androstenedione (A) in patients with hypogonadotropic hypogonadism associated with weight loss (HH) and in normal menstruating women (N)." | 3.67 | Reduced conversion of dehydroepiandrosterone into estrogens in women having hypogonadotropic hypogonadism associated with weight loss. ( Bolelli, G; Bonavia, M; Bulletti, C; Ferraretti, AP; Flamigni, C; Franceschetti, F; Jasonni, VM, 1986) |
" The transectional or longitudinal study of the plasma levels of dehydroepiandrosterone, its sulfate (DHAS), delta 4-androstenedione, testosterone, and 170H-progesterone in 121 children with a variety of clinical disorders in which adrenarchal and gonadal maturations are dissociated (precocious adrenarche, precocious or delayed puberty, adrenal insufficiency, gonadal dysgenesis, hypogonadotropism hypogonadotrophic) is presented." | 3.66 | [Does adrenarche really play a determining role in pubertal development? A study of the dissociations between adrenarche and gonadarche. The failure of dehydroepiandrosterone sulfate treatment in delayed adrenarche]. ( David, M; de Peretti, E; Forest, MG; Sempe, M, 1982) |
"Obesity is an issue that is increasingly affecting ageing men." | 2.41 | Impact of obesity on hypogonadism in the andropause. ( Pu, SJ; Tan, RS, 2002) |
"Hypogonadism was associated with decreased levels of a number of testosterone precursors." | 1.72 | [Features of steroidogenesis in men with hypogonadism and type 2 diabetes]. ( Chernova, MO; Ioutsi, VA; Mel'nichenko, GA; Mokrysheva, NG; Rozhivanov, RV; Shestakova, MV, 2022) |
"The classification of hereditary ataxias of unknown etiology is difficult because of the heterogeneity of these diseases." | 1.29 | Primary hypogonadism in females with infantile onset spinocerebellar ataxia. ( Koskinen, T; Pihko, H; Voutilainen, R, 1995) |
"Besides marked bone loss, hypogonadotropic hypogonadism was found in 3 male patients, while normal LH, FSH concentration values were measured in 3 female patients." | 1.28 | Is dehydroepiandrosterone-sulphate a possible pathogenetic factor in osteopenia of patients with iron overload? ( Czink, E; Horváth, C; Malek, AA; Siklósi, G, 1991) |
"Polycystic ovarian syndrome and hypogonadotropic hypogonadism occurred significantly more often in women with TLE than in the general female population." | 1.27 | Reproductive endocrine disorders in women with partial seizures of temporal lobe origin. ( Geschwind, N; Herzog, AG; Schomer, DL; Seibel, MM; Vaitukaitis, JL, 1986) |
"Children with Turner's syndrome and hypergonadotrophic males had the response in elevated DHA levels while ACTH-induced DHA response related to bone-age matched controls." | 1.26 | Responsiveness of cortisol and dehydroepiandrosterone to ACTH in children. ( Gupta, D; Ranke, MB; Rosendahl, W, 1982) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 46 (64.79) | 18.7374 |
1990's | 7 (9.86) | 18.2507 |
2000's | 9 (12.68) | 29.6817 |
2010's | 8 (11.27) | 24.3611 |
2020's | 1 (1.41) | 2.80 |
Authors | Studies |
---|---|
Rozhivanov, RV | 1 |
Chernova, MO | 1 |
Ioutsi, VA | 1 |
Mel'nichenko, GA | 1 |
Shestakova, MV | 1 |
Mokrysheva, NG | 1 |
Savkovic, S | 1 |
Lim, S | 1 |
Jayadev, V | 1 |
Conway, A | 1 |
Turner, L | 1 |
Curtis, D | 1 |
Goebel, C | 1 |
Handelsman, DJ | 1 |
Pluchino, N | 1 |
Carmignani, A | 1 |
Cubeddu, A | 1 |
Santoro, A | 1 |
Cela, V | 1 |
Errasti, T | 1 |
Alcalà, TE | 1 |
Giton, F | 1 |
Trabado, S | 1 |
Maione, L | 1 |
Sarfati, J | 1 |
Le Bouc, Y | 1 |
Brailly-Tabard, S | 1 |
Fiet, J | 1 |
Young, J | 1 |
Zimmerman, Y | 2 |
Foidart, JM | 2 |
Pintiaux, A | 2 |
Minon, JM | 2 |
Fauser, BC | 2 |
Cobey, K | 2 |
Coelingh Bennink, HJ | 2 |
Kovac, JR | 1 |
Pan, M | 1 |
Arent, S | 1 |
Lipshultz, LI | 1 |
Diamanti-Kandarakis, E | 1 |
Dattilo, M | 1 |
Macut, D | 1 |
Duntas, L | 1 |
Gonos, ES | 1 |
Goulis, DG | 1 |
Gantenbein, CK | 1 |
Kapetanou, M | 1 |
Koukkou, E | 1 |
Lambrinoudaki, I | 1 |
Michalaki, M | 1 |
Eftekhari-Nader, S | 1 |
Pasquali, R | 1 |
Peppa, M | 1 |
Tzanela, M | 1 |
Vassilatou, E | 1 |
Vryonidou, A | 1 |
Shibayama, Y | 1 |
Higashi, T | 1 |
Shimada, K | 1 |
Odani, A | 1 |
Mizokami, A | 1 |
Konaka, H | 1 |
Koh, E | 1 |
Namiki, M | 1 |
Colameco, S | 1 |
Coren, JS | 1 |
Kim, NN | 1 |
Schaaf, L | 1 |
Stalla, GK | 1 |
Araujo, AB | 1 |
Wittert, GA | 1 |
Tan, RS | 1 |
Pu, SJ | 1 |
INADA, T | 1 |
EBISUTA, K | 1 |
WELLER, O | 1 |
ROSNER, JM | 1 |
CONTE, NF | 1 |
BRIGGS, JH | 1 |
CHAO, PY | 1 |
SUDMAN, EM | 1 |
FORSHAM, PH | 1 |
VILLEE, DB | 1 |
MACGILLIVRAY, M | 1 |
CRAWFORD, JD | 1 |
SCULLY, RE | 1 |
KLIMAN, B | 1 |
DENEVE, L | 1 |
VERMEULEN, A | 3 |
Cuzin, B | 1 |
Giuliano, F | 1 |
Jamin, Ch | 1 |
Legros, JJ | 1 |
Lejeune, H | 1 |
Rigot, JM | 1 |
Roger, M | 1 |
Kliesch, S | 1 |
Kaufman, JM | 1 |
Cohen, HN | 1 |
Hay, ID | 1 |
Beastall, GH | 1 |
Thomson, JA | 1 |
D'Agata, R | 1 |
Vicari, E | 1 |
Aliffi, A | 1 |
Maugeri, G | 1 |
Mongioì, A | 1 |
Gulizia, S | 1 |
Forest, MG | 1 |
de Peretti, E | 1 |
David, M | 1 |
Sempe, M | 1 |
Berg, R | 1 |
Berg, G | 1 |
Edman, G | 1 |
Svensson, J | 1 |
Aström, G | 1 |
Ranke, MB | 1 |
Rosendahl, W | 1 |
Gupta, D | 1 |
Reiter, EO | 1 |
Duckett, GE | 1 |
Root, AW | 1 |
Bahnsen, M | 1 |
Gluud, C | 1 |
Johnsen, SG | 1 |
Bennett, P | 1 |
Svenstrup, S | 1 |
Micic, S | 1 |
Dietrichson, O | 1 |
Svendsen, LB | 1 |
Brodthagen, UA | 1 |
Luboshitzky, R | 1 |
Lavi, S | 1 |
Thuma, I | 1 |
Lavie, P | 1 |
Koskinen, T | 1 |
Pihko, H | 1 |
Voutilainen, R | 1 |
Ozata, M | 2 |
Bulur, M | 2 |
Bingol, N | 1 |
Beyhan, Z | 1 |
Corakci, A | 2 |
Bolu, E | 2 |
Gundogan, MA | 2 |
Yildirimkaya, M | 1 |
Yilmaz, K | 1 |
Medraś, M | 1 |
Jankowska, E | 1 |
Weinstein, RL | 1 |
Reitz, RE | 1 |
Harris, E | 1 |
Mahendra, P | 1 |
McGarrigle, HH | 1 |
Linch, DC | 1 |
Chatterjee, R | 1 |
Christiansen, P | 1 |
Sizonenko, PC | 4 |
Paunier, L | 2 |
Stahl, F | 1 |
Copeland, KC | 1 |
Boyar, RM | 1 |
Czink, E | 1 |
Horváth, C | 1 |
Malek, AA | 1 |
Siklósi, G | 1 |
Frank-Raue, K | 1 |
Raue, F | 1 |
Korth-Schütz, S | 1 |
Vecsei, P | 1 |
Ziegler, R | 1 |
Herzog, AG | 1 |
Seibel, MM | 1 |
Schomer, DL | 1 |
Vaitukaitis, JL | 1 |
Geschwind, N | 1 |
Bulletti, C | 1 |
Jasonni, VM | 1 |
Bolelli, G | 1 |
Franceschetti, F | 1 |
Ferraretti, AP | 1 |
Bonavia, M | 1 |
Flamigni, C | 1 |
Oesterling, JE | 1 |
Epstein, JI | 1 |
Walsh, PC | 1 |
Schwarz, HP | 1 |
Zimmermann, A | 1 |
Carasso, A | 1 |
Zuppinger, K | 1 |
Kaufman, FR | 1 |
Donnell, GN | 1 |
Lobo, RA | 1 |
Yanaihara, T | 1 |
Hirato, K | 1 |
Nakayama, T | 1 |
Schmidt, H | 1 |
Starcevic, Z | 1 |
Teller, WM | 1 |
Krese, A | 1 |
Teller, W | 1 |
Horký, K | 2 |
Küchel, O | 2 |
Gregorvá, I | 1 |
Stárka, L | 2 |
Zimprich, H | 1 |
Conti, C | 1 |
Sciarra, F | 1 |
Cathro, DM | 2 |
Jänne, O | 1 |
Perheentupa, J | 1 |
Vihko, R | 1 |
Gregorová, I | 1 |
Saez, JM | 1 |
Bertrand, J | 1 |
Scurry, MT | 1 |
Bruton, J | 1 |
Barry, KG | 1 |
Kelch, RP | 1 |
Jenner, MR | 1 |
Weinstein, R | 1 |
Kaplan, SL | 1 |
Grumbach, MM | 1 |
Drucker, WD | 1 |
Blumberg, JM | 1 |
Gandy, HM | 1 |
David, RR | 1 |
Verde, AL | 1 |
Boon, DA | 1 |
Keenan, RE | 1 |
Salunwhite, WR | 1 |
Aceto, T | 1 |
Crook, D | 1 |
Thomas, JP | 1 |
Oake, RJ | 1 |
Takahara, J | 1 |
Hashimoto, K | 1 |
Ofuji, T | 1 |
Drobnjak, P | 1 |
Grizelj, V | 1 |
Stanetti, P | 1 |
Longhino, N | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Antioxidants vs.Ovarian Bio-stimulation Therapy to Rescue the Ovarian Reserve[NCT03621683] | 78 participants (Actual) | Interventional | 2016-01-06 | Completed | |||
Pharmacokinetics of a Novel Oral Testosterone Undecanoate Formulation With Concomitant Inhibition of 5alpha-Reductase by Finasteride[NCT00842751] | Phase 2 | 11 participants (Actual) | Interventional | 2009-07-31 | Completed | ||
Pharmacokinetics of Modified Slow-Release Oral Testosterone Over 10 Days in Normal Men With Experimental Hypogonadism[NCT01167829] | Phase 1 | 14 participants (Actual) | Interventional | 2010-07-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Area under the curve of serum testosterone Pharmacokinetic measures time-weighted mean concentration calculated as area under the concentration curve (AUC) divided by time from initiation of dosing for the morning dose and corrected for differences in baseline hormone concentration. (NCT00842751)
Timeframe: 0,1,2,4,8,and 12-hour post dose
Intervention | ng*hr/dL (Geometric Mean) |
---|---|
Acyline +Testosterone Undecanoate + Placebo | 471 |
Acyline +Testosterone Undecanoate + 0.5mg Finasteride | 444 |
Acyline +Testosterone Undecanoate + 1mg Finasteride | 543 |
Area under the curve of serum dihydrotestosterone (NCT00842751)
Timeframe: 0,1,2,4,8,and 12-hour post dose
Intervention | ng*hr/dL (Geometric Mean) |
---|---|
Acyline +Testosterone Undecanoate + Placebo | 154 |
Acyline + Testosterone Undecanoate + 0.5mg Finasteride | 118 |
Acyline + Testosterone Undecanoate + 1mg Finasteride | 125 |
Area under the curve of serum estradiol (NCT00842751)
Timeframe: 0,1,2,4,8,and 12-hour post dose
Intervention | ng*hr/dL (Geometric Mean) |
---|---|
Acyline +Testosterone Undecanoate + Placebo | 7.9 |
Acyline + Testosterone Undecanoate + 0.5mg Finasteride | 6.5 |
Acyline +Testosterone Undecanoate + 1mg Finasteride | 7.2 |
Free T normal range 4.7-18 ng/dL (NCT01167829)
Timeframe: baseline & day 9
Intervention | ng/dL (Geometric Mean) | |
---|---|---|
Day 1-2 | Day 9-10 | |
300 mg Oral Testosterone | 24 | 21 |
Free T normal range 4.7-18 ng/dL (NCT01167829)
Timeframe: baseline & day 9
Intervention | ng/dL (Geometric Mean) | |
---|---|---|
Day 1-2 | Day 9-10 | |
300 mg Oral Testosterone | 8.7 | 8.3 |
(NCT01167829)
Timeframe: baseline & day 9
Intervention | ng/dL (Geometric Mean) | |
---|---|---|
Day 1 | Day 9 | |
300 mg Oral Testosterone | 233 | 142 |
(NCT01167829)
Timeframe: baseline & day 9
Intervention | ng/dL (Geometric Mean) | |
---|---|---|
Day 1 | Day 9 | |
300 mg Oral Testosterone | 14 | 9 |
(NCT01167829)
Timeframe: baseline & day 9
Intervention | ng/dL (Geometric Mean) | |
---|---|---|
Day 1 | Day 9 | |
300 mg Oral Testosterone | 31 | 22 |
initial pharmacokinetics [PK] (day 1) of oral testosterone dosed 3 times daily and the PK after 9 days of treatment (NCT01167829)
Timeframe: baseline & day 9
Intervention | ng/dL (Geometric Mean) | |
---|---|---|
Day 1 | Day 9 | |
Acyline and 300 mg Oral Testosterone | 924 | 741 |
(NCT01167829)
Timeframe: baseline & day 9
Intervention | ng/dL (Geometric Mean) | |
---|---|---|
Day 1 | Day 9 | |
Acyline and 300 mg Oral Testosterone | 96 | 69 |
(NCT01167829)
Timeframe: baseline & day 9
Intervention | ng/dL (Geometric Mean) | |
---|---|---|
Day 1 | Day 9 | |
300 mg Oral Testosterone | 11 | 7 |
(NCT01167829)
Timeframe: baseline & day 9
Intervention | ng/dL (Geometric Mean) | |
---|---|---|
Day 1 | Day 9 | |
300 mg Oral Testosterone | 27 | 19 |
initial 24-hour pharmacokinetics (PK) of oral testosterone dosed 3 times daily and post 24-hour PK after 9 days of treatment (NCT01167829)
Timeframe: baseline & day 9
Intervention | ng/dL (Geometric Mean) | |
---|---|---|
Day 1 | Day 9 | |
Acyine and 300 mg Oral Testosterone | 378 | 315 |
15 reviews available for dehydroepiandrosterone and Hypogonadism
Article | Year |
---|---|
Androgen therapy in women: for whom and when.
Topics: Aging; Androgens; Dehydroepiandrosterone; Female; Hormone Replacement Therapy; Humans; Hypogonadism; | 2013 |
Dietary Adjuncts for Improving Testosterone Levels in Hypogonadal Males.
Topics: Androstenediol; Androstenedione; Dehydroepiandrosterone; Dietary Supplements; Hormone Replacement Th | 2016 |
MECHANISMS IN ENDOCRINOLOGY: Aging and anti-aging: a Combo-Endocrinology overview.
Topics: Adjuvants, Immunologic; Aging; Androgens; Antioxidants; Circadian Rhythm; Dehydroepiandrosterone; Di | 2017 |
Opioid-induced endocrinopathy.
Topics: Adrenal Glands; Analgesics, Opioid; Dehydroepiandrosterone; Endocrine System Diseases; Humans; Hypog | 2009 |
Sex steroid hormones in diabetes-induced sexual dysfunction: focus on the female gender.
Topics: Clitoris; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Estrogens; Female; Glucose Intolerance; | 2009 |
Endocrinology of the aging male.
Topics: Aging; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Follicle Stimulating Hormone; Humans; H | 2011 |
Impact of obesity on hypogonadism in the andropause.
Topics: Aged; Aging; Body Composition; Climacteric; Dehydroepiandrosterone; Diabetes Mellitus; Humans; Hypog | 2002 |
[Hormone therapy in the aging male. Estrogen, DHEA, melatonin, somatotropin].
Topics: Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Estrogens; Growth Hormone; Hormone Replaceme | 2004 |
The decline of androgen levels in elderly men and its clinical and therapeutic implications.
Topics: Aged; Aging; Androgens; Atherosclerosis; Clinical Trials as Topic; Coronary Disease; Dehydroepiandro | 2005 |
Decreased androgen levels and obesity in men.
Topics: Dehydroepiandrosterone; Humans; Hypogonadism; Leydig Cells; Male; Obesity; Sex Hormone-Binding Globu | 1996 |
[On the healthy male aging: hormonal aspects].
Topics: Aged; Aging; Climacteric; Dehydroepiandrosterone; Health Status; Human Growth Hormone; Humans; Hypog | 1999 |
Endocrine laboratory findings in pubertal distrubances.
Topics: Adolescent; Adrenal Glands; Adult; Age Factors; Androstenedione; Child; Child, Preschool; Clomiphene | 1975 |
Preadolescent and adolescent endocrinology: physiology and physiopathology. II. Hormonal changes during abnormal pubertal development.
Topics: Adolescent; Adrenocortical Hyperfunction; Androgen Antagonists; Child; Dehydroepiandrosterone; Estra | 1978 |
[The determination, secretion and plasma concentration of androgens].
Topics: Adolescent; Adult; Age Factors; Androgen Antagonists; Androgen-Binding Protein; Androgens; Androstan | 1979 |
Control of the onset of puberty.
Topics: Adolescent; Adrenocorticotropic Hormone; Androstenedione; Anorexia Nervosa; Dehydroepiandrosterone; | 1978 |
4 trials available for dehydroepiandrosterone and Hypogonadism
Article | Year |
---|---|
Restoring testosterone levels by adding dehydroepiandrosterone to a drospirenone containing combined oral contraceptive: II. Clinical effects.
Topics: Acne Vulgaris; Adolescent; Adult; Androgen Antagonists; Androstenes; Belgium; Contraceptives, Oral, | 2015 |
Restoring testosterone levels by adding dehydroepiandrosterone to a drospirenone containing combined oral contraceptive: I. Endocrine effects.
Topics: Adolescent; Adult; Androgen Antagonists; Androstane-3,17-diol; Androstenedione; Androstenes; Belgium | 2015 |
Simultaneous determination of salivary testosterone and dehydroepiandrosterone using LC-MS/MS: Method development and evaluation of applicability for diagnosis and medication for late-onset hypogonadism.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Chromatography, Liquid; Dehydroepiandrosterone; Humans | 2009 |
Qualitative alterations in urinary 17-ketosteroid excretion during aminoglutethimide administration.
Topics: 17-Ketosteroids; Adrenocortical Hyperfunction; Aminoglutethimide; Androsterone; Aniline Compounds; A | 1969 |
52 other studies available for dehydroepiandrosterone and Hypogonadism
Article | Year |
---|---|
[Features of steroidogenesis in men with hypogonadism and type 2 diabetes].
Topics: 17-alpha-Hydroxyprogesterone; Androgens; Cross-Sectional Studies; Dehydroepiandrosterone; Diabetes M | 2022 |
Urine and Serum Sex Steroid Profile in Testosterone-Treated Transgender and Hypogonadal and Healthy Control Men.
Topics: Adolescent; Adult; Androgens; Androsterone; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; | 2018 |
Sex steroids, precursors, and metabolite deficiencies in men with isolated hypogonadotropic hypogonadism and panhypopituitarism: a GCMS-based comparative study.
Topics: Adult; Androstenedione; Chromatography, Gas; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; | 2015 |
[Endocrine changes with advancing age].
Topics: Aged; Dehydroepiandrosterone; Erectile Dysfunction; Female; Humans; Hypogonadism; Insulin-Like Growt | 2009 |
[A mixed agent of testosterone, dehydroepiandrosterone, mare serum gonadotropin and human chorionic gonadotropin (Gonasteron) in the treatment of male hypogonadism].
Topics: Animals; Chorionic Gonadotropin; Dehydroepiandrosterone; Female; Gonadotropins; Gonadotropins, Equin | 1963 |
[Comparative studies on the metabolic effect of testosterone and 1-methyl-delta-androstenolone in cases with primary hypogonadism].
Topics: Androgens; Calcium; Dehydroepiandrosterone; Eunuchism; Humans; Hypogonadism; Klinefelter Syndrome; M | 1962 |
DETERMINATION OF URINARY TESTOSTERONE BY CHROMATOGRAPHY AND COLORIMETRY: FINDINGS IN NORMAL SUBJECTS AND IN PATIENTS WITH ENDOCRINE DISEASES.
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Androg | 1965 |
ANDROGEN SYNTHESIS BY TESTICULAR TISSUE FROM A PATIENT WITH GONADAL INSUFFICIENCY.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Androgens; Biopsy; Chromatography; Dehydroepiandrosterone; | 1965 |
THE DETERMINATION OF 17-OXOSTEROID SULPHATES IN HUMAN PLASMA.
Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenalectomy; Androsterone; Blood Chemical Analysis; | 1965 |
[Investigation, treatment and monitoring of late-onset hypogonadism in males: the official guidelines of the International Society for the Study of the Study of the Aging Male (ISSAM) with comments].
Topics: Aging; Androgens; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; France; Hormones; Human Gr | 2003 |
Failure of adrenal androgen to induce puberty in familial cytomegalic adrenocortical hypoplasia.
Topics: Adrenal Cortex Diseases; Adrenal Insufficiency; Adult; Dehydroepiandrosterone; Dehydroepiandrosteron | 1982 |
Testicular responsiveness to chronic human chorionic gonadotropin administration in hypogonadotropic hypogonadism.
Topics: Adolescent; Adult; Androstenedione; Chorionic Gonadotropin; Dehydroepiandrosterone; Estradiol; Human | 1982 |
[Does adrenarche really play a determining role in pubertal development? A study of the dissociations between adrenarche and gonadarche. The failure of dehydroepiandrosterone sulfate treatment in delayed adrenarche].
Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Diseases; Androgens; Child; Dehydroepiandrosterone; Dehyd | 1982 |
Androgens and personality in normal men and men operated for hypospadias in childhood.
Topics: Adult; Androgens; Child; Child, Preschool; Dehydroepiandrosterone; Follicle Stimulating Hormone; Fol | 1983 |
Responsiveness of cortisol and dehydroepiandrosterone to ACTH in children.
Topics: Adolescent; Adrenocorticotropic Hormone; Child; Child, Preschool; Dehydroepiandrosterone; Humans; Hy | 1982 |
Responses to constant infusion of LH-RH in girls with primary hypogonadism.
Topics: Adolescent; Adult; Androstenedione; Child; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; E | 1980 |
Pituitary-testicular function in patients with alcoholic cirrhosis of the liver.
Topics: Adult; Aged; Dehydroepiandrosterone; Estradiol; Estrone; Gonadotropins; Gynecomastia; Humans; Hypogo | 1981 |
Increased nocturnal melatonin secretion in male patients with hypogonadotropic hypogonadism and delayed puberty.
Topics: Activity Cycles; Adolescent; Cohort Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; | 1995 |
Primary hypogonadism in females with infantile onset spinocerebellar ataxia.
Topics: Adolescent; Adult; Age of Onset; Brain; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepia | 1995 |
Daytime plasma melatonin levels in male hypogonadism.
Topics: Adult; Chorionic Gonadotropin; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulf | 1996 |
Effects of gonadotropin and testosterone treatments on Lipoprotein(a), high density lipoprotein particles, and other lipoprotein levels in male hypogonadism.
Topics: Adult; Apolipoprotein A-I; Apolipoprotein A-II; Chorionic Gonadotropin; Dehydroepiandrosterone; Dehy | 1996 |
Pituitary-testicular responsiveness in male hypogonadotropic hypogonadism.
Topics: Adult; Chorionic Gonadotropin; Clomiphene; Dehydroepiandrosterone; Estrogen Antagonists; Follicle St | 1974 |
Gynaecomastia with hypergonadotrophic hypogonadism and Leydig cell insufficiency in recipients of high-dose chemotherapy or chemo-radiotherapy.
Topics: Adult; Antineoplastic Agents; Bone Marrow Transplantation; Combined Modality Therapy; Dehydroepiandr | 2001 |
Urinary gonadotrophins in the Sertoli-Cell-only syndrome.
Topics: Adult; Androgens; Androsterone; Biological Assay; Biopsy; Castration; Dehydroepiandrosterone; Dexame | 1975 |
Hormonal changes in puberty III: Correlation of plasma dehydroepiandrosterone, testosterone, FSH, and LH with stages of puberty and bone age in normal boys and girls and in patients with Addison's disease or hypogonadism or with premature or late adrenarc
Topics: Addison Disease; Adolescent; Bone Development; Child; Dehydroepiandrosterone; Female; Follicle Stimu | 1975 |
The secretion of adrenal androgens and growth patterns of patients with hypogonadotropic hypogonadism and isiopathic delayed puberty.
Topics: Adolescent; Adrenal Cortex; Adrenal Glands; Adult; Age Determination by Skeleton; Androgens; Dehydro | 1977 |
Is dehydroepiandrosterone-sulphate a possible pathogenetic factor in osteopenia of patients with iron overload?
Topics: Adult; Bone Density; Bone Diseases, Metabolic; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfat | 1991 |
[Clinical features and diagnosis of mild 3-beta-hydroxysteroid dehydrogenase deficiency in men].
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Body Height; Dehyd | 1989 |
Reproductive endocrine disorders in women with partial seizures of temporal lobe origin.
Topics: Adult; Dehydroepiandrosterone; Endocrine System Diseases; Epilepsy, Temporal Lobe; Estradiol; Female | 1986 |
Reduced conversion of dehydroepiandrosterone into estrogens in women having hypogonadotropic hypogonadism associated with weight loss.
Topics: Adult; Amenorrhea; Androstenedione; Body Weight; Dehydroepiandrosterone; Dehydroepiandrosterone Sulf | 1986 |
The inability of adrenal androgens to stimulate the adult human prostate: an autopsy evaluation of men with hypogonadotropic hypogonadism and panhypopituitarism.
Topics: Adrenal Glands; Aged; Aged, 80 and over; Androstenedione; Dehydroepiandrosterone; Dehydroepiandroste | 1986 |
Feminization in a galactosemic girl in the presence of hypergonadotropic hypogonadism.
Topics: Adult; Amenorrhea; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Estrone; Femal | 1986 |
Ovarian androgen secretion in patients with galactosemia and premature ovarian failure.
Topics: Adolescent; Adult; Androgens; Androstenedione; Chorionic Gonadotropin; Dehydroepiandrosterone; Dehyd | 1987 |
[Placental sulfatase deficiency in Japan].
Topics: Adult; Cesarean Section; Dehydroepiandrosterone; Estriol; Estrogens; Female; Humans; Hypogonadism; I | 1987 |
[The diagnostic significance of testosterone, 17-ketosteroids and estrogen secretion in male hypogonadism].
Topics: Adult; Androsterone; Animals; Castration; Chromatography; Dehydroepiandrosterone; Estradiol; Estriol | 1965 |
[Excretion of C-19 and C21 steroids in the urine under normal and pathological conditions of development and maturation].
Topics: 17-Ketosteroids; Adolescent; Adult; Age Factors; Androsterone; Carbon Isotopes; Child; Child, Presch | 1967 |
[Steroid spectrum of diabetic men in relationship to their potency].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Androsterone; Cortisone; Dehydroepiandrosterone; | 1966 |
[Adolescence. I. C-19 and C21 steroid metabolism during puberty].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Age Factors; Androgens; Carbon Isotop | 1967 |
[Clinical and biochemical studies in a female patient with mixed gonadal dysgenesis].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Androsterone; Body | 1969 |
Two cases of germinal aplasia: plasma concentration and in vitro biosynthesis of androgens.
Topics: 17-Ketosteroids; Adult; Androgens; Carbon Isotopes; Dehydroepiandrosterone; Eczema; Estradiol; Estro | 1968 |
The effect of clomiphene on the androgen production of pubertal and prepubertal boys.
Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenal Gland Diseases; Androgens; Child; Child, Presc | 1969 |
Plasma and urinary steroids in an eight-year-old boy with 3-beta-hydxysteroid dehydrogenase deficiency.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aldosterone; Androsterone; Child; Dehydroepiandro | 1970 |
Effect of aminoglutethimide on extraglandular metabolism of exogenous testosterone.
Topics: 17-Ketosteroids; Adult; Aminoglutethimide; Androsterone; Aniline Compounds; Anticonvulsants; Dehydro | 1971 |
The effect of clomiphene on the plasma androgens of prepubertal and pubertal boys.
Topics: 17-Ketosteroids; Adolescent; Adrenal Insufficiency; Androgens; Androstanes; Child; Child, Preschool; | 1971 |
The effect of chorionic gonadotropin on steroid excretion.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adolescent; Adult; Androsterone; Chorionic G | 1971 |
Estradiol and testosterone secretion by human, simian, and canine testes, in males with hypogonadism and in male pseudohermaphrodites with the feminizing testes syndrome.
Topics: Adult; Androgen-Insensitivity Syndrome; Animals; Chorionic Gonadotropin; Chromatography, Thin Layer; | 1972 |
Estradiol and testosterone secretion by human, simian, and canine testes, in males with hypogonadism and in male pseudohermaphrodites with the feminizing testes syndrome.
Topics: Adult; Androgen-Insensitivity Syndrome; Animals; Chorionic Gonadotropin; Chromatography, Thin Layer; | 1972 |
Estradiol and testosterone secretion by human, simian, and canine testes, in males with hypogonadism and in male pseudohermaphrodites with the feminizing testes syndrome.
Topics: Adult; Androgen-Insensitivity Syndrome; Animals; Chorionic Gonadotropin; Chromatography, Thin Layer; | 1972 |
Estradiol and testosterone secretion by human, simian, and canine testes, in males with hypogonadism and in male pseudohermaphrodites with the feminizing testes syndrome.
Topics: Adult; Androgen-Insensitivity Syndrome; Animals; Chorionic Gonadotropin; Chromatography, Thin Layer; | 1972 |
Biologic activity of dehydroepiandrosterone sulfate in man.
Topics: Adolescent; Adult; Dehydroepiandrosterone; Down Syndrome; Female; Humans; Hydroxyproline; Hypogonadi | 1972 |
Conjugated and unconjugated plasma androgens in normal children.
Topics: 17-Ketosteroids; Adolescent; Adult; Age Factors; Androgens; Androstanes; Androsterone; Bromine; Carb | 1972 |
The routine measurement of urinary 17-oxosteroids and 17-oxogenic steroids using gas-liquid chromatography.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adult; Androgens; Androsterone; Chromat | 1972 |
Androgen metabolism in the skin of hirsute women.
Topics: 17-Ketosteroids; Adult; Androstanes; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepian | 1974 |
[Gas liquid chromatography analysis of urinary neutral steroid fractions in normal persons and patients with various diseases].
Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormon | 1970 |
Primary hypogonadotrophic hypogonadism in women.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Dehy | 1969 |