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dehydroepiandrosterone and Huntington Disease

dehydroepiandrosterone has been researched along with Huntington Disease in 3 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leblhuber, F2
Haller, H1
Steiner, K1
Fuchs, D1
Peichl, M1
Neubauer, C1
Reisecker, F1
Steinparz, FX1
Windhager, E1
Maschek, W1
Bruyn, GW1
de Yong, FH1
van der Molen, JH1

Trials

1 trial available for dehydroepiandrosterone and Huntington Disease

ArticleYear
Serum dehydroepiandrosterone and cortisol measurements in Huntington's chorea.
    Journal of the neurological sciences, 1995, Volume: 132, Issue:1

    Topics: Adult; Cortisone; Dehydroepiandrosterone; Humans; Huntington Disease; Male; Tomography, Emission-Com

1995

Other Studies

2 other studies available for dehydroepiandrosterone and Huntington Disease

ArticleYear
DHEA treatment of Alzheimer's disease: A randomized, double-blind, placebo-controlled trial.
    Neurology, 2004, Mar-23, Volume: 62, Issue:6

    Topics: Age Factors; Aged; Aging; Alzheimer Disease; Dehydroepiandrosterone; Double-Blind Method; Female; Hi

2004
Huntington's chorea and the adrenal.
    British medical journal, 1972, Feb-19, Volume: 1, Issue:5798

    Topics: Adrenal Glands; Dehydroepiandrosterone; Humans; Huntington Disease; Hydrocortisone; Sulfates; Testos

1972