Page last updated: 2024-11-07

dehydroepiandrosterone and Hemorrhagic Shock

dehydroepiandrosterone has been researched along with Hemorrhagic Shock in 9 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
"Dehydroepiandrosterone (DHEA) improves survival after trauma and sepsis, while mechanisms of action are not yet fully understood."3.75DHEA-dependent and organ-specific regulation of TNF-alpha mRNA expression in a murine polymicrobial sepsis and trauma model. ( Barkhausen, T; Hildebrand, F; Krettek, C; van Griensven, M, 2009)
"To determine whether the steroid hormone dehydroepiandrosterone (DHEA) improves cellular immune functions after hemorrhagic shock."3.71The effect of dehydroepiandrosterone on hemorrhage-induced suppression of cellular immune function. ( Nickel, E; Oberbeck, R; Pape, HC; Schmitz, D; Tschernig, T; von Griensven, M; Wittwer, T, 2002)
"The TPR was increased during hemorrhagic shock, and then gradually decreased to baseline levels during and after resuscitation."1.33Effect of DHEA on the hemodynamic response to resuscitation in a porcine model of hemorrhagic shock. ( Chang, B; Helling, T; Morrison, DC; Nguyen, C; Steppacher, R; Tibbs, BM; Van Way, CW; Woodall, C; Yang, R, 2006)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's6 (66.67)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barkhausen, T1
Hildebrand, F1
Krettek, C1
van Griensven, M1
Oberbeck, R2
Kobbe, P1
Cotton, BA1
Nickel, E1
von Griensven, M1
Tschernig, T1
Wittwer, T1
Schmitz, D1
Pape, HC1
Knoferl, MW1
Angele, MK2
Catania, RA1
Diodato, MD1
Bland, KI2
Chaudry, IH3
Frantz, MC1
Yang, R1
Tibbs, BM1
Chang, B1
Nguyen, C1
Woodall, C1
Steppacher, R1
Helling, T1
Morrison, DC1
Van Way, CW1
Jarrar, D1
Wang, P1
Cioffi, WG1
Guss, R1
Badder, EM1
Seaton, JF1
Harrison, TS1

Reviews

3 reviews available for dehydroepiandrosterone and Hemorrhagic Shock

ArticleYear
Dehydroepiandrosterone (DHEA): a steroid with multiple effects. Is there any possible option in the treatment of critical illness?
    Current medicinal chemistry, 2010, Volume: 17, Issue:11

    Topics: Animals; Central Nervous System; Critical Illness; Dehydroepiandrosterone; Humans; Mice; Sepsis; Sho

2010
Alternative fluids for prehospital resuscitation: "pharmacological" resuscitation fluids.
    The Journal of trauma, 2011, Volume: 70, Issue:5 Suppl

    Topics: Adjuvants, Immunologic; Animals; Dehydroepiandrosterone; Emergency Medical Services; Enzyme Inhibito

2011
Gender and sex hormones influence the response to trauma and sepsis: potential therapeutic approaches.
    Clinics (Sao Paulo, Brazil), 2006, Volume: 61, Issue:5

    Topics: Adjuvants, Immunologic; Androgen Receptor Antagonists; Androgens; Blood Circulation; Dehydroepiandro

2006

Other Studies

6 other studies available for dehydroepiandrosterone and Hemorrhagic Shock

ArticleYear
DHEA-dependent and organ-specific regulation of TNF-alpha mRNA expression in a murine polymicrobial sepsis and trauma model.
    Critical care (London, England), 2009, Volume: 13, Issue:4

    Topics: Animals; Base Sequence; Dehydroepiandrosterone; Disease Models, Animal; DNA Primers; Femoral Fractur

2009
The effect of dehydroepiandrosterone on hemorrhage-induced suppression of cellular immune function.
    Intensive care medicine, 2002, Volume: 28, Issue:7

    Topics: Animals; Apoptosis; CD4-CD8 Ratio; Dehydroepiandrosterone; Enzyme-Linked Immunosorbent Assay; Flow C

2002
Immunomodulatory effects of dehydroepiandrosterone in proestrus female mice after trauma-hemorrhage.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 95, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Cytokines; Dehydroepiandrosterone; Estradiol; Female; Interleukin-6

2003
Effect of DHEA on the hemodynamic response to resuscitation in a porcine model of hemorrhagic shock.
    The Journal of trauma, 2006, Volume: 61, Issue:6

    Topics: Adjuvants, Immunologic; Animals; Blood Pressure; Cardiac Output; Dehydroepiandrosterone; Disease Mod

2006
Mechanisms of the salutary effects of dehydroepiandrosterone after trauma-hemorrhage: direct or indirect effects on cardiac and hepatocellular functions?
    Archives of surgery (Chicago, Ill. : 1960), 2000, Volume: 135, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Cardiac Output; Dehydroepiandrosterone; Estradiol; Estrogen Antagon

2000
Cardiac output following adrenomedullary deprivation.
    Surgery, gynecology & obstetrics, 1977, Volume: 145, Issue:4

    Topics: Adrenal Cortex; Adrenal Glands; Adrenal Medulla; Adrenalectomy; Animals; Blood Volume; Cardiac Outpu

1977