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dehydroepiandrosterone and Hemolysis

dehydroepiandrosterone has been researched along with Hemolysis in 7 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research Excerpts

ExcerptRelevanceReference
" Our team has observed that dehydroepiandrosterone (DHEA) has a protective effect against in vitro and in vivo ribavirin-induced hemolysis."7.85DHEA prevents ribavirin-induced anemia via inhibition of glucose-6-phosphate dehydrogenase. ( Bodeau, S; Brochot, E; Domange, B; Duverlie, G; Garçon, L; Handala, L; Helle, F; Nguyen-Khac, E; Ouled-Haddou, H, 2017)
" Our team has observed that dehydroepiandrosterone (DHEA) has a protective effect against in vitro and in vivo ribavirin-induced hemolysis."3.85DHEA prevents ribavirin-induced anemia via inhibition of glucose-6-phosphate dehydrogenase. ( Bodeau, S; Brochot, E; Domange, B; Duverlie, G; Garçon, L; Handala, L; Helle, F; Nguyen-Khac, E; Ouled-Haddou, H, 2017)
"The effect of dehydroepiandrosterone (DEA), an adrenal androgen successfully used for preventing attacks in hereditary angioneurotic edema (HANE) patients was studied on the activation of classical and alternative complement pathway."3.67Inhibition of the complement activation by an adrenal androgen, dehydroepiandrosterone. ( Fehér, GK; Fehér, T; Füst, G; Hidvégi, T; Koó, E, 1984)
"Dehydroepiandrosterone (DHEA) is a natural hormone with many beneficial properties including an anticancer activity."1.46Syntheses and antiproliferative activities of novel phosphatidylcholines containing dehydroepiandrosterone moieties. ( Grudniewska, A; Jarosz, J; Kłobucki, M; Maciejewska, G; Smuga, DA; Smuga, M; Wawrzeńczyk, C; Wietrzyk, J, 2017)
"The hemolysis was also not inhibited by addition of EDTA, catalase, superoxide dismutase, glucose or a radical scavenger including mannitol, dimethylsulfoxide and alpha-tocopherol, indicating a non-oxidative mechanism."1.30Hemolytic effects of dehydroepiandrosterone in vitro. ( Hu, ML; Ng, HP; Shih, MK, 1997)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Handala, L1
Domange, B1
Ouled-Haddou, H1
Garçon, L1
Nguyen-Khac, E1
Helle, F1
Bodeau, S1
Duverlie, G1
Brochot, E1
Ke, Y1
Gonthier, R1
Simard, JN1
Labrie, F1
Kłobucki, M1
Grudniewska, A1
Smuga, DA1
Smuga, M1
Jarosz, J1
Wietrzyk, J1
Maciejewska, G1
Wawrzeńczyk, C1
Hidvégi, T1
Fehér, GK1
Fehér, T1
Koó, E1
Füst, G1
Hu, ML1
Ng, HP1
Shih, MK1
Oertel, GW1
Rebelein, I1
Mulder, E1
Lamers-Stahlhofen, GJ1
van der Molen, HJ1

Other Studies

7 other studies available for dehydroepiandrosterone and Hemolysis

ArticleYear
DHEA prevents ribavirin-induced anemia via inhibition of glucose-6-phosphate dehydrogenase.
    Antiviral research, 2017, Volume: 146

    Topics: Adenosine Triphosphate; Anemia; Antiviral Agents; Dehydroepiandrosterone; Erythrocytes; Glucosephosp

2017
A validated LC-MS/MS method for the sensitive quantitation of serum 7alpha hydroxy-, 7beta hydroxy- and 7keto-dehydroepiandrosterone using a novel derivatization reagent.
    Steroids, 2016, Volume: 108

    Topics: Adult; Blood Chemical Analysis; Calibration; Chromatography, Liquid; Dehydroepiandrosterone; Female;

2016
Syntheses and antiproliferative activities of novel phosphatidylcholines containing dehydroepiandrosterone moieties.
    Steroids, 2017, Volume: 118

    Topics: Anti-Bacterial Agents; Antifungal Agents; Biofilms; Candida; Candida albicans; Dehydroepiandrosteron

2017
Inhibition of the complement activation by an adrenal androgen, dehydroepiandrosterone.
    Complement (Basel, Switzerland), 1984, Volume: 1, Issue:4

    Topics: Angioedema; Complement Activation; Complement C1; Complement C1 Inactivator Proteins; Complement C4;

1984
Hemolytic effects of dehydroepiandrosterone in vitro.
    Life sciences, 1997, Volume: 61, Issue:21

    Topics: Dehydroepiandrosterone; Free Radical Scavengers; Glutathione; Hemolysis; Humans; Lipid Peroxidation;

1997
Effects of dehydroepiandrosterone and its conjugates upon the activity of glucose-6-phosphate dehydrogenase in human erythrocytes.
    Biochimica et biophysica acta, 1969, Jul-30, Volume: 184, Issue:2

    Topics: Cerebrosides; Dehydroepiandrosterone; Depression, Chemical; Erythrocytes; Glucosephosphate Dehydroge

1969
Isolation and characterization of 17 -hydroxy steroid dehydrogenase from human erythrocytes.
    The Biochemical journal, 1972, Volume: 127, Issue:4

    Topics: Ammonium Sulfate; Carbon Isotopes; Chloromercuribenzoates; Chromatography; Chromatography, Gel; Dehy

1972