dehydroepiandrosterone has been researched along with Heart Failure in 17 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The secretion of dehydroepiandrosterone sulfate (DHEAS) decreases with age, and the incidence of heart failure rises in the elderly population." | 7.74 | Dehydroepiandrosterone levels vary according as heart failure condition in patients with idiopathic dilated cardiomyopathy. ( Kawano, H; Kinoshita, Y; Nagayoshi, Y; Ogawa, H; Soejima, H; Tanaka, Y; Yamabe, H, 2008) |
| "To analyze the association of circulating dehydroepiandrosterone sulfate (DHEA-S) levels with cardiovascular outcomes in patients with chronic Chagas cardiomyopathy (CCM) diagnosis." | 4.12 | Circulating DHEA-S levels and major cardiovascular outcomes in chronic Chagas cardiomyopathy: A prospective cohort study. ( Bautista-Niño, PK; Echeverría, LE; Eisenga, MF; Gómez-Ochoa, SA; Hunziker, L; Muka, T; Rojas, LZ, 2022) |
| "The secretion of dehydroepiandrosterone sulfate (DHEAS) decreases with age, and the incidence of heart failure rises in the elderly population." | 3.74 | Dehydroepiandrosterone levels vary according as heart failure condition in patients with idiopathic dilated cardiomyopathy. ( Kawano, H; Kinoshita, Y; Nagayoshi, Y; Ogawa, H; Soejima, H; Tanaka, Y; Yamabe, H, 2008) |
| "The relation between adrenal steroid hormone imbalance, as quantified by the cortisol/dehydroepiandrosterone (DHEA) ratio, and hemoglobin concentrations was appraised in 92 men with stable chronic heart failure (CHF)." | 3.73 | Association of deranged adrenal steroid metabolism with anemia in chronic heart failure. ( Anker, SD; Cicoira, M; Coats, AJ; Crosato, M; Doehner, W; John, M; Kalra, PR; Okonko, DO; Poole-Wilson, PA, 2005) |
| "We sought to assess the possible relations between clinical severity of chronic heart failure and catabolic factors, specifically tumor necrosis factor (TNF), soluble TNF receptors 1 and 2 (sTNFR-1 and sTNFR-2), cortisol, testosterone and dehydroepiandrosterone (DHEA)." | 3.69 | Tumor necrosis factor and steroid metabolism in chronic heart failure: possible relation to muscle wasting. ( Anker, SD; Clark, AL; Coats, AJ; Hellewell, PG; Kemp, M; Salsbury, C; Teixeira, MM, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (17.65) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Rojas, LZ | 1 |
| Gómez-Ochoa, SA | 1 |
| Echeverría, LE | 1 |
| Bautista-Niño, PK | 1 |
| Hunziker, L | 1 |
| Eisenga, MF | 1 |
| Muka, T | 1 |
| Yeap, BB | 1 |
| Dwivedi, G | 1 |
| Zhang, YT | 1 |
| Xue, JJ | 1 |
| Wang, Q | 1 |
| Cheng, SY | 1 |
| Chen, ZC | 1 |
| Li, HY | 1 |
| Shan, JJ | 1 |
| Cheng, KL | 1 |
| Zeng, WJ | 1 |
| Thierer, J | 1 |
| Acosta, A | 1 |
| Vainstein, N | 1 |
| Sultan, M | 1 |
| Francesia, A | 1 |
| Marino, J | 1 |
| Prado, AH | 1 |
| Guglielmone, R | 1 |
| Trivi, M | 1 |
| Boero, L | 1 |
| Brites, F | 1 |
| Anker, S | 1 |
| Pastor-Pérez, FJ | 1 |
| Manzano-Fernández, S | 1 |
| Garrido Bravo, IP | 1 |
| Nicolás, F | 1 |
| Tornel, PL | 1 |
| Lax, A | 1 |
| de la Morena, G | 1 |
| Valdés, M | 1 |
| Pascual-Figal, DA | 1 |
| Moyad, MA | 1 |
| Nakamura, S | 1 |
| Yoshimura, M | 4 |
| Nakayama, M | 1 |
| Ito, T | 1 |
| Mizuno, Y | 1 |
| Harada, E | 1 |
| Sakamoto, T | 1 |
| Saito, Y | 1 |
| Nakao, K | 1 |
| Yasue, H | 1 |
| Ogawa, H | 2 |
| Okonko, DO | 1 |
| Crosato, M | 1 |
| Kalra, PR | 1 |
| Cicoira, M | 1 |
| John, M | 1 |
| Doehner, W | 1 |
| Coats, AJ | 3 |
| Poole-Wilson, PA | 2 |
| Anker, SD | 3 |
| Kawano, H | 1 |
| Nagayoshi, Y | 1 |
| Soejima, H | 1 |
| Tanaka, Y | 1 |
| Yamabe, H | 1 |
| Kinoshita, Y | 1 |
| Clark, AL | 2 |
| Kemp, M | 1 |
| Salsbury, C | 1 |
| Teixeira, MM | 1 |
| Hellewell, PG | 1 |
| Niebauer, J | 1 |
| Pflaum, CD | 1 |
| Strasburger, CJ | 1 |
| Hooper, J | 1 |
| Wolff, HP | 1 |
| Zaretskiĭ, MM | 1 |
| Vakhtina, TI | 1 |
| Smith, TW | 1 |
| Haber, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Relationship Between Right Atrial Volume Index, Functional Capacity and Inflammatory Biomarkers in Patients With Chronic Obstructive Lung Disease and Right Heart Affection.[NCT05366400] | 151 participants (Actual) | Observational | 2022-01-19 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for dehydroepiandrosterone and Heart Failure
| Article | Year |
|---|---|
The placebo effect and randomized trials: analysis of alternative medicine.
Topics: Androstenedione; Antioxidants; beta Carotene; Coenzymes; Complementary Therapies; Dehydroepiandroste | 2002 |
[Heart failure and renin-angiotensin-aldosterone system: studies on aldosterone].
Topics: Aldosterone; Angiotensin II; Animals; Apoptosis; Dehydroepiandrosterone; Gene Expression Regulation, | 2005 |
[Aldosterone in heart failure].
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Apoptosis; Cytochrome P-450 CYP11 | 2005 |
[Cardiac aldosterone].
Topics: Aldosterone; Dehydroepiandrosterone; Heart Failure; Humans | 2006 |
[Clinical steroid analysis, using H3 and C14 (determination of their secretion, plasma concentration, secretion rate, as well as metabolism and renal clearance rate)].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Aldosterone; Carbon Isotopes; Chemistry, Clin | 1965 |
12 other studies available for dehydroepiandrosterone and Heart Failure
| Article | Year |
|---|---|
Circulating DHEA-S levels and major cardiovascular outcomes in chronic Chagas cardiomyopathy: A prospective cohort study.
Topics: Biomarkers; Cardiomyopathies; Chagas Cardiomyopathy; Chagas Disease; Dehydroepiandrosterone; Female; | 2022 |
Androgens and Heart Failure: New Observations Illuminating an Aging Conundrum.
Topics: Aging; Androgens; Androstenedione; Dehydroepiandrosterone; Heart Failure; Humans | 2021 |
Dehydroepiandrosterone attenuates pulmonary artery and right ventricular remodeling in a rat model of pulmonary hypertension due to left heart failure.
Topics: Animals; Blotting, Western; Dehydroepiandrosterone; Disease Models, Animal; Echocardiography; Heart | 2019 |
Relation of left ventricular ejection fraction and functional capacity with metabolism and inflammation in chronic heart failure with reduced ejection fraction (from the MIMICA Study).
Topics: Adiponectin; Aged; C-Reactive Protein; Chronic Disease; Dehydroepiandrosterone; Female; Heart Failur | 2010 |
Anabolic status and functional impairment in men with mild chronic heart failure.
Topics: Chronic Disease; Dehydroepiandrosterone; Echocardiography; Electrocardiography; Exercise Test; Exerc | 2011 |
Possible association of heart failure status with synthetic balance between aldosterone and dehydroepiandrosterone in human heart.
Topics: Adult; Aged; Aldosterone; Animals; Blotting, Southern; Cardiac Catheterization; Cell Size; Cells, Cu | 2004 |
Association of deranged adrenal steroid metabolism with anemia in chronic heart failure.
Topics: Adrenal Glands; Aged; Anemia; Dehydroepiandrosterone; Heart Failure; Hemoglobins; Humans; Hydrocorti | 2005 |
Dehydroepiandrosterone levels vary according as heart failure condition in patients with idiopathic dilated cardiomyopathy.
Topics: Aged; Biomarkers; Cardiomyopathy, Dilated; Dehydroepiandrosterone; Heart Failure; Humans; Male; Midd | 2008 |
Tumor necrosis factor and steroid metabolism in chronic heart failure: possible relation to muscle wasting.
Topics: Aged; Antigens, CD; Body Mass Index; Case-Control Studies; Dehydroepiandrosterone; Exercise Test; He | 1997 |
Deficient insulin-like growth factor I in chronic heart failure predicts altered body composition, anabolic deficiency, cytokine and neurohormonal activation.
Topics: Adrenergic alpha-Agonists; Age Factors; Aged; Anatomy, Cross-Sectional; Body Composition; Body Mass | 1998 |
[Protein composition of the blood and excretion of corticosteroids in patients with arteriosclerotic cardiosclerosis with chronic circulatory insufficiency].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Blood Proteins; Coronary Diseas | 1969 |
The clinical value of serum digitalis glycoside concentrations in the evaluation of drug toxicity.
Topics: Adult; Aged; Antibody Specificity; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Cho | 1971 |