dehydroepiandrosterone has been researched along with HIV Coinfection in 51 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| " DHEA dosing was flexible (100-400 mg/day)." | 2.72 | Placebo-controlled trial of dehydroepiandrosterone (DHEA) for treatment of nonmajor depression in patients with HIV/AIDS. ( Ferrando, SJ; McElhiney, MC; McGrath, PJ; Rabkin, JG; Rabkin, R, 2006) |
| "Since most forms of Kaposi sarcoma are much more common in men than in women, the aim of this study was to examine serum concentrations of sex steroids in HIV positive men with and without Kaposi sarcoma." | 1.29 | Differences in androgens of HIV positive patients with and without Kaposi sarcoma. ( Christeff, N; Costagliola, D; Gharakhanian, S; Nunez, EA; Rozenbaum, W; Thobie, N; Winter, C; Wirbel, E, 1995) |
| "Dehydroepiandrosterone (DHEA) has been shown to have a broad spectrum of biological functions, to be bioavailable orally and to be relatively nontoxic." | 1.29 | Inhibition of 3'azido-3'deoxythymidine-resistant HIV-1 infection by dehydroepiandrosterone in vitro. ( Henderson, EE; Schwartz, A; Yang, JY, 1994) |
| "DHEA's background and use as an AIDS treatment are reviewed." | 1.29 | DHEA and AIDS. ( James, JS, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (35.29) | 18.2507 |
| 2000's | 19 (37.25) | 29.6817 |
| 2010's | 7 (13.73) | 24.3611 |
| 2020's | 7 (13.73) | 2.80 |
| Authors | Studies |
|---|---|
| Chu, L | 1 |
| Liu, S | 1 |
| Wu, Y | 1 |
| Yang, J | 1 |
| Qiao, S | 2 |
| Zhou, Y | 1 |
| Deng, H | 2 |
| Li, X | 2 |
| Shen, Z | 1 |
| Gordián-Arroyo, A | 1 |
| Reame, N | 1 |
| Gutierrez, J | 1 |
| Liu, J | 1 |
| Ganzhorn, S | 1 |
| Igwe, KC | 1 |
| Laing, K | 1 |
| Schnall, R | 1 |
| Vecchione, MB | 4 |
| Laufer, N | 3 |
| Sued, O | 5 |
| Corti, M | 1 |
| Salomon, H | 3 |
| Quiroga, MF | 5 |
| Fazeli, PL | 1 |
| Waldrop-Valverde, D | 1 |
| Yigit, I | 1 |
| Turan, B | 1 |
| Edberg, J | 1 |
| Kempf, M | 1 |
| Vance, D | 1 |
| Mukerji, SS | 1 |
| Misra, V | 1 |
| Lorenz, DR | 1 |
| Chettimada, S | 1 |
| Keller, K | 1 |
| Letendre, S | 1 |
| Ellis, RJ | 1 |
| Morgello, S | 1 |
| Parker, RA | 1 |
| Gabuzda, D | 1 |
| Mancus, G | 1 |
| Cimino, AN | 1 |
| Hasan, MZ | 1 |
| Campbell, JC | 1 |
| Winch, PJ | 1 |
| Sharps, P | 1 |
| Tsuyuki, K | 1 |
| Granger, DA | 1 |
| Stockman, JK | 1 |
| Angerami, MT | 4 |
| Suarez, GV | 3 |
| Turk, G | 2 |
| Ben, G | 2 |
| Ameri, D | 3 |
| Gonzalez, D | 2 |
| Parodi, LM | 1 |
| Giavedoni, LD | 1 |
| Maidana, P | 3 |
| Fabre, B | 2 |
| Mesch, V | 3 |
| Eiras, J | 1 |
| Marquez, C | 1 |
| Pérez, HM | 1 |
| Bruttomesso, AC | 1 |
| Kariyawasam, D | 1 |
| Simon, A | 1 |
| Laborde, K | 1 |
| Parat, S | 1 |
| Souchon, PF | 1 |
| Frange, P | 1 |
| Blanche, S | 1 |
| Polak, M | 1 |
| Peixoto, C | 1 |
| Devicari Cheda, JN | 1 |
| Nardi, AE | 1 |
| Veras, AB | 1 |
| Cardoso, A | 1 |
| Le, T | 1 |
| Cash-Goldwasser, S | 1 |
| Tho, PV | 1 |
| Lan, NP | 1 |
| Campbell, JI | 1 |
| van Doorn, HR | 1 |
| Lam, NT | 1 |
| Trung, NV | 1 |
| Trinh, DT | 1 |
| Van Kinh, N | 1 |
| Wertheim, HF | 1 |
| Ruiz, MJ | 1 |
| Cahn, P | 2 |
| Bottasso, OA | 1 |
| Zilioli, S | 1 |
| Chen, Z | 1 |
| Pan, J | 1 |
| Guo, W | 1 |
| Poretsky, L | 2 |
| Song, L | 1 |
| Brillon, DJ | 2 |
| Ferrando, S | 2 |
| Chiu, J | 2 |
| McElhiney, M | 2 |
| Ferenczi, A | 2 |
| Sison, C | 1 |
| Haller, I | 2 |
| Rabkin, J | 3 |
| Santucci, N | 1 |
| Francos, JL | 1 |
| Wallach, J | 1 |
| Bottasso, O | 1 |
| Christeff, N | 6 |
| De Truchis, P | 1 |
| Melchior, JC | 2 |
| Perronne, C | 1 |
| Gougeon, ML | 2 |
| McCain, NL | 1 |
| Munjas, BA | 1 |
| Munro, CL | 1 |
| Elswick, RK | 1 |
| Robins, JL | 1 |
| Ferreira-Gonzalez, A | 1 |
| Baliko, B | 1 |
| Kaplowitz, LG | 1 |
| Fisher, EJ | 1 |
| Garrett, CT | 1 |
| Brigle, KE | 1 |
| Kendall, LC | 1 |
| Lucas, V | 1 |
| Cochran, KL | 1 |
| Chen, CC | 1 |
| Parker, CR | 1 |
| Cameron, DR | 1 |
| Braunstein, GD | 1 |
| James, JS | 3 |
| Koutkia, P | 1 |
| Berry, J | 1 |
| Eaton, K | 1 |
| Breu, J | 1 |
| Grinspoon, S | 1 |
| Rabkin, JG | 1 |
| McElhiney, MC | 1 |
| Rabkin, R | 1 |
| McGrath, PJ | 1 |
| Ferrando, SJ | 1 |
| Sison, MC | 1 |
| Chantry, CJ | 1 |
| Frederick, MM | 1 |
| Meyer, WA | 1 |
| Handelsman, E | 1 |
| Rich, K | 1 |
| Paul, ME | 1 |
| Diaz, C | 1 |
| Cooper, ER | 1 |
| Foca, M | 1 |
| Adeniyi-Jones, SK | 1 |
| Moye, J | 1 |
| Abrams, DI | 1 |
| Shade, SB | 1 |
| Couey, P | 1 |
| McCune, JM | 1 |
| Lo, J | 1 |
| Bacchetti, P | 1 |
| Chang, B | 1 |
| Epling, L | 1 |
| Liegler, T | 1 |
| Grant, RM | 1 |
| Winter, C | 1 |
| Gharakhanian, S | 3 |
| Thobie, N | 3 |
| Wirbel, E | 1 |
| Costagliola, D | 1 |
| Nunez, EA | 5 |
| Rozenbaum, W | 2 |
| Clerici, M | 1 |
| Bevilacqua, M | 1 |
| Vago, T | 1 |
| Villa, ML | 1 |
| Shearer, GM | 1 |
| Norbiato, G | 1 |
| Yang, JY | 1 |
| Schwartz, A | 1 |
| Henderson, EE | 1 |
| Wisniewski, TL | 1 |
| Hilton, CW | 1 |
| Morse, EV | 1 |
| Svec, F | 1 |
| Brind, J | 1 |
| Danenberg, HD | 1 |
| Ben-Yehuda, A | 1 |
| Lortholary, O | 2 |
| Casassus, P | 1 |
| Veyssier, P | 1 |
| Torri, O | 1 |
| Guillevin, L | 1 |
| McCarty, MF | 1 |
| Gherbi, N | 1 |
| Mammes, O | 1 |
| Dalle, MT | 1 |
| Smith, KJ | 1 |
| Skelton, HG | 1 |
| Kaiser, J | 1 |
| Kingston, T | 1 |
| Frincke, J | 1 |
| Piketty, C | 1 |
| Jayle, D | 1 |
| Gonzalez-Canali, G | 1 |
| Debuire, B | 1 |
| Baulieu, EE | 1 |
| Kazatchkine, MD | 1 |
| Jacobson, MA | 1 |
| Fusaro, RE | 1 |
| Galmarini, M | 1 |
| Lang, W | 1 |
| Oberfield, SE | 1 |
| Kairam, R | 1 |
| Bakshi, S | 1 |
| Bamji, M | 1 |
| Bhushan, V | 1 |
| Mayes, D | 1 |
| Levine, LS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| In Vivo Targeting of Neuroactive Steroid and Immune Networks for Depression in People Living With HIV[NCT05570812] | Phase 2 | 120 participants (Anticipated) | Interventional | 2023-03-03 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for dehydroepiandrosterone and HIV Coinfection
| Article | Year |
|---|---|
The effects of dehydroepiandrosterone (DHEA) in the treatment of depression and depressive symptoms in other psychiatric and medical illnesses: a systematic review.
Topics: Adrenal Insufficiency; Anorexia Nervosa; Antidepressive Agents; Databases, Bibliographic; Dehydroepi | 2014 |
Adrenal androgens and the immune system.
Topics: Acquired Immunodeficiency Syndrome; Adrenal Glands; Androgens; Animals; Arthritis, Rheumatoid; Criti | 2004 |
The use of dehydroepiandrosterone therapy in clinical practice.
Topics: Adrenal Insufficiency; Aging; Alzheimer Disease; Bone Density; Cardiovascular Diseases; Dehydroepian | 2005 |
[Physiologic importance of dehydroepiandrosterone].
Topics: Adult; Alzheimer Disease; Dehydroepiandrosterone; Female; HIV Infections; Humans; Lipoproteins; Male | 1996 |
9 trials available for dehydroepiandrosterone and HIV Coinfection
| Article | Year |
|---|---|
Metabolic and hormonal effects of oral DHEA in premenopausal women with HIV infection: a randomized, prospective, placebo-controlled pilot study.
Topics: Administration, Oral; Affect; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Double-B | 2009 |
Effects of stress management on PNI-based outcomes in persons with HIV disease.
Topics: Adaptation, Psychological; Adult; Analysis of Variance; Dehydroepiandrosterone; Female; Health Statu | 2003 |
Increased adrenal androgen secretion with inhibition of 11beta-hydroxylase in HIV-infected women.
Topics: Adolescent; Adrenal Glands; Adult; Androgens; Androstenedione; Cortodoxone; Cosyntropin; Dehydroepia | 2006 |
Placebo-controlled trial of dehydroepiandrosterone (DHEA) for treatment of nonmajor depression in patients with HIV/AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adjuvants, Immunologic; Adolescent; Adult; Aged; Dehydroepiandro | 2006 |
Endocrine effects of oral dehydroepiandrosterone in men with HIV infection: a prospective, randomized, double-blind, placebo-controlled trial.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Dehydroep | 2006 |
Dehydroepiandrosterone (DHEA) effects on HIV replication and host immunity: a randomized placebo-controlled study.
Topics: Adjuvants, Immunologic; Adult; Biological Availability; Black or African American; Dehydroepiandrost | 2007 |
Serum cortisol and DHEA concentrations during HIV infection.
Topics: Adult; Blotting, Western; Cachexia; CD4-CD8 Ratio; Dehydroepiandrosterone; HIV Infections; HIV Serop | 1997 |
Changes in DHEA levels in people taking anti-HIV therapy.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Dehydroepiandrosterone; HIV Infections; Humans; Male; | 2001 |
DHEA for depression?
Topics: Affect; Body Composition; Dehydroepiandrosterone; Depression; Female; HIV Infections; Humans; Male; | 2001 |
38 other studies available for dehydroepiandrosterone and HIV Coinfection
| Article | Year |
|---|---|
Hair levels of steroid, endocannabinoid, and the ratio biomarkers predict viral suppression among people living with HIV/AIDS in China.
Topics: Acquired Immunodeficiency Syndrome; Biomarkers; China; Cross-Sectional Studies; Dehydroepiandrostero | 2022 |
Do correlates of white matter features differ between older men and women living with human immunodeficiency virus?
Topics: Aged; Cross-Sectional Studies; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; HIV; HI | 2023 |
7-oxo-DHEA enhances impaired M. tuberculosis-specific T cell responses during HIV-TB coinfection.
Topics: Adult; Chronic Disease; Coinfection; Cross-Sectional Studies; Dehydroepiandrosterone; Female; HIV In | 2020 |
An Exploratory Study of Correlates of Allostatic Load in Older People Living With HIV.
Topics: Aged; Allostasis; Biomarkers; Black or African American; Body Mass Index; C-Reactive Protein; Choles | 2020 |
Low Neuroactive Steroids Identifies a Biological Subtype of Depression in Adults with Human Immunodeficiency Virus on Suppressive Antiretroviral Therapy.
Topics: Adult; Dehydroepiandrosterone; Depression; HIV Infections; Humans; Hydrocortisone; Hypothalamo-Hypop | 2021 |
Residential Greenness Positively Associated with the Cortisol to DHEA Ratio among Urban-Dwelling African American Women at Risk for HIV.
Topics: Adolescent; Adult; Black or African American; Cross-Sectional Studies; Dehydroepiandrosterone; Ecosy | 2021 |
Immune variations throughout the course of tuberculosis treatment and its relationship with adrenal hormone changes in HIV-1 patients co-infected with Mycobacterium tuberculosis.
Topics: Adrenal Cortex Hormones; Adult; Antitubercular Agents; Biomarkers; Coinfection; Cytokines; Dehydroep | 2021 |
Determination of dehydroepiandrosterone and its biologically active oxygenated metabolites in human plasma evinces a hormonal imbalance during HIV-TB coinfection.
Topics: CD4 Lymphocyte Count; Chromatography, High Pressure Liquid; Coinfection; Dehydroepiandrosterone; End | 2018 |
Adrenal enzyme impairment in neonates and adolescents treated with ritonavir and protease inhibitors for HIV exposure or infection.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Anti-HIV Age | 2014 |
Diagnosing Rhodococcus equi infections in a setting where tuberculosis is highly endemic: a double challenge.
Topics: Actinomycetales Infections; Adult; Anti-Bacterial Agents; Anti-HIV Agents; Ascorbic Acid; Cholecalci | 2015 |
HIV-TB coinfection impairs CD8(+) T-cell differentiation and function while dehydroepiandrosterone improves cytotoxic antitubercular immune responses.
Topics: Adult; CD4-Positive T-Lymphocytes; Cell Differentiation; Coinfection; Cross-Sectional Studies; Dehyd | 2015 |
Hair Measurements of Cortisol, DHEA, and DHEA to Cortisol Ratio as Biomarkers of Chronic Stress among People Living with HIV in China: Known-Group Validation.
Topics: Adult; Biomarkers; China; Chronic Disease; Dehydroepiandrosterone; Female; Hair; HIV Infections; HIV | 2017 |
Dynamics of adrenal steroids are related to variations in Th1 and Treg populations during Mycobacterium tuberculosis infection in HIV positive persons.
Topics: Adrenal Glands; Adult; Coinfection; Dehydroepiandrosterone; Female; Forkhead Transcription Factors; | 2012 |
Longitudinal evolution of HIV-1-associated lipodystrophy is correlated to serum cortisol:DHEA ratio and IFN-alpha.
Topics: Adult; Antiretroviral Therapy, Highly Active; Apolipoprotein A-I; Apolipoproteins B; Cholesterol; Ch | 2002 |
DHEA access threatened?
Topics: Controlled Clinical Trials as Topic; Dehydroepiandrosterone; Drug Approval; HIV Infections; Humans; | 2005 |
Endocrine abnormalities and impaired growth in human immunodeficiency virus-infected children.
Topics: Body Height; Body Weight; Case-Control Studies; Child; Child, Preschool; Dehydroepiandrosterone; Fem | 2007 |
Differences in androgens of HIV positive patients with and without Kaposi sarcoma.
Topics: Adult; Androgens; Androstenedione; CD4 Lymphocyte Count; Dehydroepiandrosterone; Dehydroepiandroster | 1995 |
An immunoendocrinological hypothesis of HIV infection.
Topics: Antibody Formation; Cell Death; Cytokines; Dehydroepiandrosterone; Glucocorticoids; HIV Infections; | 1994 |
Inhibition of 3'azido-3'deoxythymidine-resistant HIV-1 infection by dehydroepiandrosterone in vitro.
Topics: Cytopathogenic Effect, Viral; Dehydroepiandrosterone; Drug Resistance, Microbial; HIV Infections; HI | 1994 |
The relationship of serum DHEA-S and cortisol levels to measures of immune function in human immunodeficiency virus-related illness.
Topics: Adult; CD4-Positive T-Lymphocytes; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; HIV Infec | 1993 |
Spotlight on DHEA: a marker for progression of HIV infection?
Topics: Acquired Immunodeficiency Syndrome; Biomarkers; CD4 Lymphocyte Count; Dehydroepiandrosterone; Diseas | 1996 |
Relationship between sex steroid hormone levels and CD4 lymphocytes in HIV infected men.
Topics: Adult; Androgens; CD4 Lymphocyte Count; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estr | 1996 |
Promotion of interleukin-2 activity as a strategy for 'rejuvenating' geriatric immune function.
Topics: Aging; Animals; Antioxidants; Carotenoids; Chromium; Clonal Anergy; Dehydroepiandrosterone; Diet; HI | 1997 |
Changes in cortisol/DHEA ratio in HIV-infected men are related to immunological and metabolic perturbations leading to malnutrition and lipodystrophy.
Topics: Dehydroepiandrosterone; HIV Infections; HIV-1; Humans; Hydrocortisone; Lipodystrophy; Male; Neuroimm | 2000 |
Peroxisomal proliferator-activated ligand therapy for HIV lipodystrophy.
Topics: Anti-HIV Agents; Cyclooxygenase Inhibitors; Dehydroepiandrosterone; Drug Therapy, Combination; HIV I | 2001 |
DHEA and AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Aging; Dehydroepiandrosterone; Dehydroepiandrostero | 1996 |
DHEA clinical experience: interview with Jon Kaiser, M.D. Interview by John S. James.
Topics: Adult; Dehydroepiandrosterone; Female; HIV Infections; Humans; Male; Middle Aged | 1996 |
DHEA: threat to access?
Topics: Dehydroepiandrosterone; HIV Infections; Humans; Quality of Life | 1996 |
DHEA: modest viral load reduction in patients.
Topics: Dehydroepiandrosterone; Female; HIV; HIV Infections; Humans; Male; Polymerase Chain Reaction; Treatm | 1996 |
DHEA for depression.
Topics: Clinical Trials as Topic; Dehydroepiandrosterone; Depression; Female; HIV Infections; Humans; Male; | 1997 |
HE2000 begins clinical trials: interview with James Frincke, Ph.D. Interview by John S. James.
Topics: Animals; Anti-HIV Agents; Clinical Trials as Topic; Dehydroepiandrosterone; HIV Infections; Humans | 1999 |
DHEA. Is it useful for treating depression?
Topics: Clinical Trials as Topic; Dehydroepiandrosterone; Depression; Female; HIV Infections; Humans; Male | 2001 |
DHEA--background.
Topics: CD4 Lymphocyte Count; Dehydroepiandrosterone; HIV Infections; Humans; Viral Load | 2001 |
DHEA--cautions and concerns.
Topics: Contraindications; Dehydroepiandrosterone; Depression; HIV Infections; Humans; Neoplasms, Hormone-De | 2001 |
Low plasma levels of dehydroepiandrosterone (DHEA) and incidence of lipodystrophy.
Topics: Adult; Antiretroviral Therapy, Highly Active; Biological Availability; Dehydroepiandrosterone; Dehyd | 2001 |
Evidence for changes in adrenal and testicular steroids during HIV infection.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Cortex Hormones; Adult; Androstenedione; Dehydroep | 1992 |
Decreased serum dehydroepiandrosterone is associated with an increased progression of human immunodeficiency virus infection in men with CD4 cell counts of 200-499.
Topics: Adult; CD4-Positive T-Lymphocytes; Cohort Studies; Dehydroepiandrosterone; HIV Infections; Humans; L | 1991 |
Steroid response to adrenocorticotropin stimulation in children with human immunodeficiency virus infection.
Topics: Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Aldosterone; Child; Child, Preschool; Co | 1990 |