Page last updated: 2024-11-07

dehydroepiandrosterone and Glioma

dehydroepiandrosterone has been researched along with Glioma in 4 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
" C6 rat glioma tumor cells in culture biosynthesize both pregnenolone (P) and D."3.70Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells. ( Cascio, C; Lieberman, S; Lin, YY; Papadopoulos, V; Prasad, VV, 1998)
"Cell invasion and metastasis were measured by cell invasion assays."1.56Relationship between CYP17A1-Mediated DNA Demethylation and Proliferation, Invasion and Metastasis of Glioma Cells. ( Lv, W; Meng, L; Zhou, Y, 2020)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Meng, L1
Lv, W1
Zhou, Y1
Cascio, C1
Prasad, VV1
Lin, YY1
Lieberman, S1
Papadopoulos, V1
Schneider, N1
Lanz, S1
Ramer, R1
Schaefer, D1
Goppelt-Struebe, M1
Shin, CY1
Choi, JW1
Jang, ES1
Ju, C1
Kim, WK1
Kim, HC1
Choi, CR1
Ko, KH1

Other Studies

4 other studies available for dehydroepiandrosterone and Glioma

ArticleYear
Relationship between CYP17A1-Mediated DNA Demethylation and Proliferation, Invasion and Metastasis of Glioma Cells.
    Critical reviews in eukaryotic gene expression, 2020, Volume: 30, Issue:6

    Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dehydroepiandrosterone; DNA Demethyl

2020
Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-17, Volume: 95, Issue:6

    Topics: Aminoglutethimide; Animals; Brain Neoplasms; Cholesterol Side-Chain Cleavage Enzyme; Cytochrome P-45

1998
Up-regulation of cyclooxygenase-1 in neuroblastoma cell lines by retinoic acid and corticosteroids.
    Journal of neurochemistry, 2001, Volume: 77, Issue:2

    Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Benzimidazoles; Bucladesine; Calcimycin; Cell Differe

2001
Dehydroepiandrosterone inhibits the death of immunostimulated rat C6 glioma cells deprived of glucose.
    Brain research, 2001, Dec-20, Volume: 922, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Astrocytes; Brain; Brain Ischemia; Cell Death; Cytokines; Dehydroep

2001