dehydroepiandrosterone has been researched along with Genetic Predisposition in 7 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Because of the elevated dehydroepiandrosterone sulfate (DHEAS) levels in polycystic ovary syndrome (PCOS) and the heritability of DHEAS serum levels, genes encoding the enzymes that control the sulfation of dehydroepiandrosterone (DHEA) to DHEAS and vice versa are obvious candidate genes to explain part of the heritability of PCOS." | 3.79 | Variants in SULT2A1 affect the DHEA sulphate to DHEA ratio in patients with polycystic ovary syndrome but not the hyperandrogenic phenotype. ( de Jong, FH; Fauser, BC; Laven, JS; Louwers, YV; Stolk, L; Uitterlinden, AG; van Herwaarden, NA, 2013) |
| "Twenty-seven women with polycystic ovary syndrome and 28 of their sisters underwent an adrenocorticotropic hormone stimulation test with measurement of the steroids dehydroepiandrosterone, androstenedione, and cortisol 60 minutes later." | 3.74 | Correlation of adrenocorticotropin steroid levels between women with polycystic ovary syndrome and their sisters. ( Azziz, R; Goodarzi, MO; Guo, X; Stanczyk, FZ; Yildiz, BO, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, T | 1 |
| Li, Y | 1 |
| Louwers, YV | 1 |
| de Jong, FH | 1 |
| van Herwaarden, NA | 1 |
| Stolk, L | 1 |
| Fauser, BC | 1 |
| Uitterlinden, AG | 1 |
| Laven, JS | 1 |
| Treadwell, EL | 1 |
| Wiley, K | 1 |
| Word, B | 1 |
| Melchior, W | 1 |
| Tolleson, WH | 1 |
| Gopee, N | 1 |
| Hammons, G | 1 |
| Lyn-Cook, BD | 1 |
| Goodyer, IM | 1 |
| Croudace, T | 1 |
| Dunn, V | 1 |
| Herbert, J | 1 |
| Jones, PB | 1 |
| Philibert, P | 1 |
| Biason-Lauber, A | 1 |
| Gueorguieva, I | 1 |
| Stuckens, C | 1 |
| Pienkowski, C | 1 |
| Lebon-Labich, B | 1 |
| Paris, F | 1 |
| Sultan, C | 1 |
| Goodarzi, MO | 1 |
| Guo, X | 1 |
| Yildiz, BO | 1 |
| Stanczyk, FZ | 1 |
| Azziz, R | 1 |
| Tennent, BJ | 1 |
| Shultz, KL | 1 |
| Beamer, WG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Androgen Metabolism and Reproductive Outcome[NCT02106676] | 400 participants (Actual) | Observational | 2012-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for dehydroepiandrosterone and Genetic Predisposition
| Article | Year |
|---|---|
Steroid profiling and genetic variants in Chinese women with gestational diabetes mellitus.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Alleles; Aromatase; China; Dehydroepiandrosterone; Diabetes | 2021 |
Variants in SULT2A1 affect the DHEA sulphate to DHEA ratio in patients with polycystic ovary syndrome but not the hyperandrogenic phenotype.
Topics: Adult; Alleles; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Genetic Predispositi | 2013 |
Prolactin and Dehydroepiandrosterone Levels in Women with Systemic Lupus Erythematosus: The Role of the Extrapituitary Prolactin Promoter Polymorphism at -1149G/T.
Topics: Adult; Black or African American; Dehydroepiandrosterone; Female; Gene Expression; Gene Frequency; G | 2015 |
Cohort profile: risk patterns and processes for psychopathology emerging during adolescence: the ROOTS project.
Topics: Adolescent; Adolescent Development; Child; Dehydroepiandrosterone; Emotions; England; Genetic Predis | 2010 |
Molecular analysis of WNT4 gene in four adolescent girls with mullerian duct abnormality and hyperandrogenism (atypical Mayer-Rokitansky-Küster-Hauser syndrome).
Topics: 17-alpha-Hydroxyprogesterone; 46, XX Disorders of Sex Development; Abnormalities, Multiple; Adolesce | 2011 |
Correlation of adrenocorticotropin steroid levels between women with polycystic ovary syndrome and their sisters.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Body Mass Index; Cohort Studies; Dehydroepiandroster | 2007 |
Genetic susceptibility for C19 androgen induction of ovarian granulosa cell tumorigenesis in SWXJ strains of mice.
Topics: Adrenal Glands; Androgens; Animals; Dehydroepiandrosterone; Female; Genetic Predisposition to Diseas | 1993 |