dehydroepiandrosterone has been researched along with Fibromyalgia in 4 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with fibromyalgia (FM) consistently have adrenal hyporesponsiveness and low dehydroepiandrosterone (DHEA) levels." | 9.11 | A randomized controlled trial of dehydroepiandrosterone in postmenopausal women with fibromyalgia. ( Aubry-Rozier, B; Berner, IC; Finckh, A; So, AK, 2005) |
| "Patients with fibromyalgia (FM) consistently have adrenal hyporesponsiveness and low dehydroepiandrosterone (DHEA) levels." | 5.11 | A randomized controlled trial of dehydroepiandrosterone in postmenopausal women with fibromyalgia. ( Aubry-Rozier, B; Berner, IC; Finckh, A; So, AK, 2005) |
| " The secondary objectives were as follows: to describe demographic and clinical characteristics of male patients with FM; to evaluate basal levels of dehydroepiandrosterone sulfate (DHEAS) and total testosterone in both groups; and to investigate the relationship among pain, tender points, anxiety, and depression in these patients." | 3.76 | A comparison of quality of life, demographic and clinical characteristics of Brazilian men with fibromyalgia syndrome with male patients with depression. ( Helfenstein, M; Heymann, RE; Pollak, DF; Yoshikawa, GT, 2010) |
| "Patients with fibromyalgia have an impaired ability to activate the hypothalamic-pituitary portion of the hypothalamic-pituitary-adrenal axis as well as the sympathoadrenal system, leading to reduced ACTH and epinephrine responses to hypoglycemia." | 1.30 | Reduced hypothalamic-pituitary and sympathoadrenal responses to hypoglycemia in women with fibromyalgia syndrome. ( Adler, GK; Goldenberg, DL; Hurwitz, S; Kinsley, BT; Mossey, CJ, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pradeep, A | 1 |
| Birerdinc, A | 1 |
| Branigan, T | 1 |
| Phan, V | 1 |
| Morris, H | 1 |
| Shah, J | 1 |
| DeStefano, S | 1 |
| Sikdar, S | 1 |
| Srbely, J | 1 |
| Kumbhare, D | 1 |
| Stecco, A | 1 |
| Paik, J | 1 |
| Gerber, LH | 1 |
| Yoshikawa, GT | 1 |
| Heymann, RE | 1 |
| Helfenstein, M | 1 |
| Pollak, DF | 1 |
| Finckh, A | 1 |
| Berner, IC | 1 |
| Aubry-Rozier, B | 1 |
| So, AK | 1 |
| Adler, GK | 1 |
| Kinsley, BT | 1 |
| Hurwitz, S | 1 |
| Mossey, CJ | 1 |
| Goldenberg, DL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Spa Therapy in the Treatment of Fibromyalgia : a Randomized, Controlled, Open Multicenter Study[NCT02265029] | 220 participants (Actual) | Interventional | 2014-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for dehydroepiandrosterone and Fibromyalgia
| Article | Year |
|---|---|
A randomized controlled trial of dehydroepiandrosterone in postmenopausal women with fibromyalgia.
Topics: Aged; Cognition; Complementary Therapies; Cross-Over Studies; Dehydroepiandrosterone; Dietary Supple | 2005 |
3 other studies available for dehydroepiandrosterone and Fibromyalgia
| Article | Year |
|---|---|
Evidence for an association of serum microanalytes and myofascial pain syndrome.
Topics: Acetylcholine; Adult; Brain-Derived Neurotrophic Factor; Cytokines; Dehydroepiandrosterone; Female; | 2023 |
A comparison of quality of life, demographic and clinical characteristics of Brazilian men with fibromyalgia syndrome with male patients with depression.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Anxiety; Brazil; Dehydroepiandrosterone; Demogr | 2010 |
Reduced hypothalamic-pituitary and sympathoadrenal responses to hypoglycemia in women with fibromyalgia syndrome.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Case-Control Studies; Dehydroepiandrosterone; Ep | 1999 |