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dehydroepiandrosterone and Fatty Liver

dehydroepiandrosterone has been researched along with Fatty Liver in 11 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.

Research Excerpts

ExcerptRelevanceReference
" The fatty liver induced by orotic acid and a high sucrose diet in male rats was prevented by the administration of DHEA and/or phenobarbital (PB)."7.70Prevention of orotic-acid-induced fatty liver in male rats by dehydroepiandrosterone and/or phenobarbital. ( Goto, H; Makita, T; Yamashita, S, 1998)
"Preventive effects of dehydroepiandrosteone acetate (DHEA-A) and clofibrate (positive control substance) on the fatty liver induced by orotic acid (OA) were examined on the male Sprague-Dawley rats fed a high sucrose based diet containing 1% OA and this diet further mixed with 0."7.70Preventive effects of dehydroepiandrosterone acetate on the fatty liver induced by orotic acid in male rats. ( Goto, H; Makita, T; Yamashita, S, 1998)
"This study concentrated on the initial events triggering the development of nonalcoholic fatty liver disease induced by a high-fat plus fructose (HF-F) diet and on the possibility of delaying nonalcoholic fatty liver disease progression by adding dehydroepiandrosterone (DHEA) to the diet."3.75SREBP-1c in nonalcoholic fatty liver disease induced by Western-type high-fat diet plus fructose in rats. ( Aragno, M; Boccuzzi, G; Catalano, MG; Collino, M; Danni, O; Fantozzi, R; Tomasinelli, CE; Vercellinatto, I, 2009)
" The fatty liver induced by orotic acid and a high sucrose diet in male rats was prevented by the administration of DHEA and/or phenobarbital (PB)."3.70Prevention of orotic-acid-induced fatty liver in male rats by dehydroepiandrosterone and/or phenobarbital. ( Goto, H; Makita, T; Yamashita, S, 1998)
"Preventive effects of dehydroepiandrosteone acetate (DHEA-A) and clofibrate (positive control substance) on the fatty liver induced by orotic acid (OA) were examined on the male Sprague-Dawley rats fed a high sucrose based diet containing 1% OA and this diet further mixed with 0."3.70Preventive effects of dehydroepiandrosterone acetate on the fatty liver induced by orotic acid in male rats. ( Goto, H; Makita, T; Yamashita, S, 1998)
"Dehydroepiandrosterone (DHEA) is a popular dietary supplement and it possesses anti-oxidative and anti-inflammatory functions; however, the effect and underlying mechanism about DHEA in protecting against the occurrence and development of FLHS remain elucidated."1.72Dehydroepiandrosterone activates the GPER-mediated AMPK signaling pathway to alleviate the oxidative stress and inflammatory response in laying hens fed with high-energy and low-protein diets. ( Jiang, Z; Ma, H; Wang, H; Yang, Y; Yao, Y, 2022)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's2 (18.18)18.2507
2000's3 (27.27)29.6817
2010's2 (18.18)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Yao, Y2
Wang, H1
Yang, Y1
Jiang, Z1
Ma, H2
Li, L1
Zhao, J1
Cao, J1
Manco, M1
Bottazzo, G1
Aragno, M1
Tomasinelli, CE1
Vercellinatto, I1
Catalano, MG1
Collino, M1
Fantozzi, R1
Danni, O1
Boccuzzi, G1
Magyar, Z1
Bekesi, G1
Racz, K1
Feher, J1
Schaff, Z1
Lengyel, G1
Blazovics, A1
Illyes, G1
Szombath, D1
Hrabak, A1
Szekacs, B1
Gergics, P1
Marczell, I1
Dinya, E1
Rigo, J1
Tulassay, Z1
Koehler, E1
Swain, J1
Sanderson, S2
Krishnan, A2
Watt, K1
Charlton, M2
THEA, JP1
Angulo, P1
Chalasani, N1
Merriman, R1
Viker, K1
Charatcharoenwitthaya, P1
Gawrieh, S1
Lindor, K1
Chiodera, P1
Pignatti, D1
Maestri, E1
Zanardi, G1
Degliantoni, G1
Orlando, S1
Volpi, R1
Delsignore, R1
Goto, H2
Yamashita, S2
Makita, T2

Other Studies

11 other studies available for dehydroepiandrosterone and Fatty Liver

ArticleYear
Dehydroepiandrosterone activates the GPER-mediated AMPK signaling pathway to alleviate the oxidative stress and inflammatory response in laying hens fed with high-energy and low-protein diets.
    Life sciences, 2022, Nov-01, Volume: 308

    Topics: Abnormalities, Multiple; AMP-Activated Protein Kinases; Animal Feed; Animals; Antioxidants; Chickens

2022
Dehydroepiandrosterone protects against hepatic glycolipid metabolic disorder and insulin resistance induced by high fat via activation of AMPK-PGC-1α-NRF-1 and IRS1-AKT-GLUT2 signaling pathways.
    International journal of obesity (2005), 2020, Volume: 44, Issue:5

    Topics: AMP-Activated Protein Kinases; Animals; Dehydroepiandrosterone; Fatty Liver; Glucose Transporter Typ

2020
Does the hormone of eternal youth protect against nonalcoholic steatohepatitis?
    Hepatology (Baltimore, Md.), 2008, Volume: 48, Issue:4

    Topics: Adiponectin; Dehydroepiandrosterone; Disease Progression; Fatty Acids, Nonesterified; Fatty Liver; H

2008
SREBP-1c in nonalcoholic fatty liver disease induced by Western-type high-fat diet plus fructose in rats.
    Free radical biology & medicine, 2009, Oct-01, Volume: 47, Issue:7

    Topics: Animals; Cell Death; Dehydroepiandrosterone; Dietary Fats; Fatty Liver; Fructose; Hyperlipidemias; I

2009
Increased total scavenger capacity and decreased liver fat content in rats fed dehydroepiandrosterone and its sulphate on a high-fat diet.
    Gerontology, 2011, Volume: 57, Issue:4

    Topics: Administration, Oral; Animals; Antioxidants; Catalase; Dehydroepiandrosterone; Dehydroepiandrosteron

2011
Growth hormone, dehydroepiandrosterone and adiponectin levels in non-alcoholic steatohepatitis: an endocrine signature for advanced fibrosis in obese patients.
    Liver international : official journal of the International Association for the Study of the Liver, 2012, Volume: 32, Issue:2

    Topics: Adiponectin; Biomarkers; Dehydroepiandrosterone; Fatty Liver; Female; Growth Hormone; Humans; Liver

2012
[1-methyl-delta-1-androstenolone enanthate in hepatic steatosis].
    La Semana medica, 1963, Jan-17, Volume: 122

    Topics: Dehydroepiandrosterone; Fatty Liver; Heptanoates; Humans

1963
Low circulating levels of dehydroepiandrosterone in histologically advanced nonalcoholic fatty liver disease.
    Hepatology (Baltimore, Md.), 2008, Volume: 47, Issue:2

    Topics: Adiponectin; Adult; Biomarkers; Biopsy; Blood Glucose; C-Reactive Protein; Cohort Studies; Dehydroep

2008
[Blood levels of prolactin, dehydroepiandrosterone sulfate, cortisol, testosterone and 17-beta-estradiol in chronic alcoholism].
    Giornale di clinica medica, 1981, Volume: 62, Issue:7

    Topics: Adult; Alcoholism; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Fatty Liver; H

1981
Prevention of orotic-acid-induced fatty liver in male rats by dehydroepiandrosterone and/or phenobarbital.
    The Journal of veterinary medical science, 1998, Volume: 60, Issue:4

    Topics: Analysis of Variance; Animals; Cells, Cultured; Dehydroepiandrosterone; Dietary Sucrose; Energy Inta

1998
Preventive effects of dehydroepiandrosterone acetate on the fatty liver induced by orotic acid in male rats.
    Experimental animals, 1998, Volume: 47, Issue:4

    Topics: Animals; Clofibrate; Dehydroepiandrosterone; Diet; Fatty Liver; Hypolipidemic Agents; Liver; Male; M

1998