dehydroepiandrosterone has been researched along with Fatigue in 19 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dehydroepiandrosterone (DHEA) has been reported to improve fatigue and reduced well-being." | 9.14 | Effects of dehydroepiandrosterone on fatigue and well-being in women with quiescent systemic lupus erythematosus: a randomised controlled trial. ( Bijl, M; Bijlsma, JW; Derksen, RH; Geenen, R; Godaert, GL; Hartkamp, A, 2010) |
| "Primary Sjögren's syndrome (SS) is characterized by fatigue and low levels of serum dehydroepiandrosterone/dehydroepiandrosterone sulfate (DHEA/DHEAS)." | 9.14 | Dehydroepiandrosterone (DHEA) substitution treatment for severe fatigue in DHEA-deficient patients with primary Sjögren's syndrome. ( Forsblad-d'Elia, H; Konttinen, YT; Porola, P; Solovieva, SA; Valtysdottir, S; Virkki, LM, 2010) |
| "Dehydroepiandrosterone (DHEA) administration has been reported to improve fatigue, psychological distress, and physical disability." | 9.13 | Effect of dehydroepiandrosterone administration on fatigue, well-being, and functioning in women with primary Sjögren syndrome: a randomised controlled trial. ( Bijlsma, JW; Bootsma, H; Derksen, RH; Geenen, R; Godaert, GL; Hartkamp, A; Kruize, AA, 2008) |
| "Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) age-related withdrawal is very likely to be involved in the aging process and the onset of age-related diseases, giving rise to the question of whether preventing or compensating the decline of these steroids may have endocrine and clinical benefits." | 9.11 | Long-term low-dose dehydroepiandrosterone replacement therapy in aging males with partial androgen deficiency. ( Bernardi, F; Genazzani, AD; Genazzani, AR; Inglese, S; Lombardi, I; Luisi, M; Pieri, M; Rovati, L, 2004) |
| "Fatigue is one of the most limiting symptoms in multiple sclerosis (MS) and the mechanisms underlying its origin are poorly understood." | 5.33 | Fatigue in progressive multiple sclerosis is associated with low levels of dehydroepiandrosterone. ( Brieva, L; Comabella, M; Julià, E; Montalban, X; Nos, C; Río, J; Téllez, N; Tintoré, M, 2006) |
| "Dehydroepiandrosterone (DHEA) has been reported to improve fatigue and reduced well-being." | 5.14 | Effects of dehydroepiandrosterone on fatigue and well-being in women with quiescent systemic lupus erythematosus: a randomised controlled trial. ( Bijl, M; Bijlsma, JW; Derksen, RH; Geenen, R; Godaert, GL; Hartkamp, A, 2010) |
| "Primary Sjögren's syndrome (SS) is characterized by fatigue and low levels of serum dehydroepiandrosterone/dehydroepiandrosterone sulfate (DHEA/DHEAS)." | 5.14 | Dehydroepiandrosterone (DHEA) substitution treatment for severe fatigue in DHEA-deficient patients with primary Sjögren's syndrome. ( Forsblad-d'Elia, H; Konttinen, YT; Porola, P; Solovieva, SA; Valtysdottir, S; Virkki, LM, 2010) |
| "Dehydroepiandrosterone (DHEA) administration has been reported to improve fatigue, psychological distress, and physical disability." | 5.13 | Effect of dehydroepiandrosterone administration on fatigue, well-being, and functioning in women with primary Sjögren syndrome: a randomised controlled trial. ( Bijlsma, JW; Bootsma, H; Derksen, RH; Geenen, R; Godaert, GL; Hartkamp, A; Kruize, AA, 2008) |
| "Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) age-related withdrawal is very likely to be involved in the aging process and the onset of age-related diseases, giving rise to the question of whether preventing or compensating the decline of these steroids may have endocrine and clinical benefits." | 5.11 | Long-term low-dose dehydroepiandrosterone replacement therapy in aging males with partial androgen deficiency. ( Bernardi, F; Genazzani, AD; Genazzani, AR; Inglese, S; Lombardi, I; Luisi, M; Pieri, M; Rovati, L, 2004) |
| "The goal of this pilot study was to evaluate the effect of dehydroepiandrosterone (DHEA) on depressed mood and fatigue in HIV+ men and women, unselected for baseline DHEA level." | 5.09 | DHEA treatment for HIV+ patients: effects on mood, androgenic and anabolic parameters. ( Ferrando, SJ; Rabkin, JG; Rabkin, R; Wagner, GJ, 2000) |
| " At each occasion, mood, fatigue, dissociation, PTSD symptoms, short-term and working memory, and salivary cortisol and dehydroepiandrosterone (DHEA) were assessed." | 3.85 | The effects of captivity survival training on mood, dissociation, PTSD symptoms, cognitive performance and stress hormones. ( Cheung, B; Lieberman, HR; Morgan, CA; Suurd Ralph, C; Vartanian, O, 2017) |
| "Fatigue is one of the most limiting symptoms in multiple sclerosis (MS) and the mechanisms underlying its origin are poorly understood." | 1.33 | Fatigue in progressive multiple sclerosis is associated with low levels of dehydroepiandrosterone. ( Brieva, L; Comabella, M; Julià, E; Montalban, X; Nos, C; Río, J; Téllez, N; Tintoré, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (47.37) | 29.6817 |
| 2010's | 9 (47.37) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Amato, A | 1 |
| Ragonese, P | 1 |
| Ingoglia, S | 1 |
| Schiera, G | 1 |
| Schirò, G | 1 |
| Di Liegro, CM | 1 |
| Salemi, G | 1 |
| Di Liegro, I | 1 |
| Proia, P | 1 |
| Suurd Ralph, C | 1 |
| Vartanian, O | 1 |
| Lieberman, HR | 1 |
| Morgan, CA | 1 |
| Cheung, B | 1 |
| Cutshall, SM | 1 |
| Bergstrom, LR | 1 |
| Kalish, DJ | 1 |
| Vasquez, A | 1 |
| Porola, P | 2 |
| Virkki, L | 1 |
| Przybyla, BD | 1 |
| Laine, M | 1 |
| Patterson, TA | 1 |
| Pihakari, A | 1 |
| Konttinen, YT | 2 |
| Hartkamp, A | 3 |
| Geenen, R | 3 |
| Godaert, GL | 3 |
| Bijl, M | 2 |
| Bijlsma, JW | 3 |
| Derksen, RH | 3 |
| Virkki, LM | 1 |
| Forsblad-d'Elia, H | 1 |
| Valtysdottir, S | 1 |
| Solovieva, SA | 1 |
| Engelmann, C | 1 |
| Schneider, M | 1 |
| Kirschbaum, C | 1 |
| Grote, G | 1 |
| Dingemann, J | 1 |
| Schoof, S | 1 |
| Ure, BM | 1 |
| Houghton, CA | 1 |
| Steels, EL | 1 |
| Fassett, RG | 1 |
| Coombes, JS | 1 |
| Ouleghzal, H | 1 |
| Rosales, C | 1 |
| Raffin-Sanson, ML | 1 |
| Nadjafi-Triebsch, C | 1 |
| Huell, M | 1 |
| Burki, D | 1 |
| Rohr, UD | 1 |
| Genazzani, AR | 1 |
| Inglese, S | 1 |
| Lombardi, I | 1 |
| Pieri, M | 1 |
| Bernardi, F | 1 |
| Genazzani, AD | 1 |
| Rovati, L | 1 |
| Luisi, M | 1 |
| Payne, JK | 1 |
| Téllez, N | 1 |
| Comabella, M | 1 |
| Julià, E | 1 |
| Río, J | 1 |
| Tintoré, M | 1 |
| Brieva, L | 1 |
| Nos, C | 1 |
| Montalban, X | 1 |
| Bootsma, H | 1 |
| Kruize, AA | 1 |
| Rabkin, JG | 1 |
| Ferrando, SJ | 1 |
| Wagner, GJ | 1 |
| Rabkin, R | 1 |
| Hunt, PJ | 1 |
| Gurnell, EM | 1 |
| Huppert, FA | 1 |
| Richards, C | 1 |
| Prevost, AT | 1 |
| Wass, JA | 1 |
| Herbert, J | 1 |
| Chatterjee, VK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Fatigue and General Well-Being in Patients With Systemic Lupus Erythematosus or Primary Sjögren's Syndrome: Effects of Dehydroepiandrosterone Administration[NCT00391924] | Phase 2 | 120 participants | Interventional | 2000-05-31 | Completed | ||
| The Effect of a Higher Dose of Dehydroepiandrosterone (DHEA) Supplementation on the Number of Oocytes Obtained During IVF in Poor Ovarian Responders[NCT02357472] | Phase 4 | 50 participants (Anticipated) | Interventional | 2014-12-31 | Active, not recruiting | ||
| Sex Steroids in Sjögren's Syndrome: Effect of Substitution Treatment on Fatigue[NCT00543166] | Phase 4 | 107 participants (Actual) | Interventional | 2003-02-28 | Active, not recruiting | ||
| The Effects of Postural Education or Corrective Exercise Intervention on the Craniovertebral Angle in Young Adults With Forward Head Posture: A Randomized Controlled Trial[NCT05321654] | 79 participants (Actual) | Interventional | 2021-08-26 | Completed | |||
| Noise Reduction Programme by Work Rules and Technical Devices (i.e.SoundEar-TM)for Surgical Theathres[NCT01612754] | 16 participants (Actual) | Interventional | 2010-09-30 | Completed | |||
| Dehydroepiandrosterone(DHEA) Substitution in Adolescent and Young Women With Central Adrenal Insufficiency. A Multicenter, Randomised Double Blind Trial[NCT00575341] | Phase 3 | 23 participants (Actual) | Interventional | 2003-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for dehydroepiandrosterone and Fatigue
| Article | Year |
|---|---|
Treatment of corticotroph deficiency.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Corticotrophs; Corticotropin-Releasing Hormone; | 2012 |
The trajectory of biomarkers in symptom management for older adults with cancer.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aged; Aging; Anxiety; Biomarkers; Biomarkers, Tumor; Cy | 2006 |
10 trials available for dehydroepiandrosterone and Fatigue
| Article | Year |
|---|---|
Lactate Threshold Training Program on Patients with Multiple Sclerosis: A Multidisciplinary Approach.
Topics: Adult; Biomarkers; Brain-Derived Neurotrophic Factor; Dehydroepiandrosterone; Exercise; Exercise The | 2021 |
Effects of dehydroepiandrosterone on fatigue and well-being in women with quiescent systemic lupus erythematosus: a randomised controlled trial.
Topics: Adult; Aged; Dehydroepiandrosterone; Depression; Double-Blind Method; Fatigue; Female; Follow-Up Stu | 2010 |
Effects of dehydroepiandrosterone on fatigue and well-being in women with quiescent systemic lupus erythematosus: a randomised controlled trial.
Topics: Adult; Aged; Dehydroepiandrosterone; Depression; Double-Blind Method; Fatigue; Female; Follow-Up Stu | 2010 |
Effects of dehydroepiandrosterone on fatigue and well-being in women with quiescent systemic lupus erythematosus: a randomised controlled trial.
Topics: Adult; Aged; Dehydroepiandrosterone; Depression; Double-Blind Method; Fatigue; Female; Follow-Up Stu | 2010 |
Effects of dehydroepiandrosterone on fatigue and well-being in women with quiescent systemic lupus erythematosus: a randomised controlled trial.
Topics: Adult; Aged; Dehydroepiandrosterone; Depression; Double-Blind Method; Fatigue; Female; Follow-Up Stu | 2010 |
Dehydroepiandrosterone (DHEA) substitution treatment for severe fatigue in DHEA-deficient patients with primary Sjögren's syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cross-Over Studies; Dehydroepiandrosterone; Fatigue; Fem | 2010 |
Effects of intraoperative breaks on mental and somatic operator fatigue: a randomized clinical trial.
Topics: Adult; alpha-Amylases; Asthenopia; Attention; Child; Child, Preschool; Dehydroepiandrosterone; Elect | 2011 |
Effects of intraoperative breaks on mental and somatic operator fatigue: a randomized clinical trial.
Topics: Adult; alpha-Amylases; Asthenopia; Attention; Child; Child, Preschool; Dehydroepiandrosterone; Elect | 2011 |
Effects of intraoperative breaks on mental and somatic operator fatigue: a randomized clinical trial.
Topics: Adult; alpha-Amylases; Asthenopia; Attention; Child; Child, Preschool; Dehydroepiandrosterone; Elect | 2011 |
Effects of intraoperative breaks on mental and somatic operator fatigue: a randomized clinical trial.
Topics: Adult; alpha-Amylases; Asthenopia; Attention; Child; Child, Preschool; Dehydroepiandrosterone; Elect | 2011 |
Effects of a gliadin-combined plant superoxide dismutase extract on self-perceived fatigue in women aged 50-65 years.
Topics: Activities of Daily Living; Aged; Antioxidants; Cucumis; Dehydroepiandrosterone; Dietary Supplements | 2011 |
The effect of dehydroepiandrosterone on lumbar spine bone mineral density in patients with quiescent systemic lupus erythematosus.
Topics: Absorptiometry, Photon; Administration, Oral; Adult; Bone Density; Dehydroepiandrosterone; Diphospho | 2004 |
Long-term low-dose dehydroepiandrosterone replacement therapy in aging males with partial androgen deficiency.
Topics: Aged; Aging; Androgens; Andropause; Arthralgia; beta-Endorphin; Dehydroepiandrosterone; Dehydroepian | 2004 |
Effect of dehydroepiandrosterone administration on fatigue, well-being, and functioning in women with primary Sjögren syndrome: a randomised controlled trial.
Topics: Adult; Affect; Aged; Blood Sedimentation; Chi-Square Distribution; Dehydroepiandrosterone; Dehydroep | 2008 |
DHEA treatment for HIV+ patients: effects on mood, androgenic and anabolic parameters.
Topics: Adult; Affect; Androgens; Body Composition; CD4 Lymphocyte Count; Dehydroepiandrosterone; Dehydroepi | 2000 |
Improvement in mood and fatigue after dehydroepiandrosterone replacement in Addison's disease in a randomized, double blind trial.
Topics: Addison Disease; Adult; Affect; Aged; Body Composition; Bone Density; Cognition; Cross-Over Studies; | 2000 |
7 other studies available for dehydroepiandrosterone and Fatigue
| Article | Year |
|---|---|
The effects of captivity survival training on mood, dissociation, PTSD symptoms, cognitive performance and stress hormones.
Topics: Adult; Affect; Anxiety; Combat Disorders; Dehydroepiandrosterone; Dissociative Disorders; Fatigue; F | 2017 |
Boost energy with these everyday steps. Pacing yourself, power naps, and good nutrition help, but taking overhyped dietary supplements doesn't.
Topics: Dehydroepiandrosterone; Dietary Supplements; Fatigue; Food Preferences; Health Behavior; Humans; Mal | 2013 |
Evaluation of a functional medicine approach to treating fatigue, stress, and digestive issues in women.
Topics: Adult; Complementary Therapies; Dehydroepiandrosterone; Fatigue; Feces; Female; Humans; Hydrocortiso | 2016 |
Correspondence regarding Cutshall, Bergstrom, Kalish's "Evaluation of a functional medicine approach to treating fatigue, stress, and digestive issues in women" in Complement Ther Clin Pract 2016 May.
Topics: Dehydroepiandrosterone; Fatigue; Female; Humans | 2018 |
Androgen deficiency and defective intracrine processing of dehydroepiandrosterone in salivary glands in Sjögren's syndrome.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Adult; Aged; Androgens; Biopsy; | 2008 |
Progesterone increase under DHEA-substitution in males.
Topics: Aged; Dehydroepiandrosterone; Depression; Fatigue; Humans; Male; Middle Aged; Progesterone; Testoste | 2003 |
Fatigue in progressive multiple sclerosis is associated with low levels of dehydroepiandrosterone.
Topics: Adult; Biomarkers; Cross-Sectional Studies; Dehydroepiandrosterone; Endocrine System; Fatigue; Femal | 2006 |