dehydroepiandrosterone has been researched along with Fatigue Syndrome, Chronic in 11 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Fatigue Syndrome, Chronic: A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "An association between chronic fatigue syndrome (CFS) and abnormalities of the hypothalamo-pituitary-adrenal axis has been described, and other adrenal steroid abnormalities have been suggested." | 2.71 | Levels of DHEA and DHEAS and responses to CRH stimulation and hydrocortisone treatment in chronic fatigue syndrome. ( Cleare, AJ; Miell, JP; O'Keane, V, 2004) |
| " ii) Evidence is presented to indicate that interstitial pneumonia was associated with increased risk for depression of which the emergence is a candidate subject causally related to the long-term use of glucocorticoid." | 2.71 | The clinical course of interstitial pneumonia alias chronic fatigue syndrome under the control of megadose vitamin C infusion system with dehydroepiandrosterone-cortisol annex. ( Kodama, M; Kodama, T, 2005) |
| "Chronic fatigue syndrome is defined by the Atlanta Centers for Disease Control (Atlanta, GA, USA) as debilitating fatigue lasting for longer than 6 months." | 1.31 | Serum concentrations of some metals and steroids in patients with chronic fatigue syndrome with reference to neurological and cognitive abnormalities. ( Carstens, ME; Emsley, RA; Hugo, F; Hurly, PR; Kiss, T; Mansvelt, E; Potocnik, FC; Taljaard, JJ; Theodorou, P; van Rensburg, SJ; van Zijl, P, 2001) |
| "The symptoms of Gulf War syndrome are compatible with the hypothesis that the immune system of affected individuals is biased towards a Th2-cytokine pattern." | 1.30 | Gulf War syndrome: is it due to a systemic shift in cytokine balance towards a Th2 profile? ( Rook, GA; Zumla, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jason, L | 1 |
| Sorenson, M | 1 |
| Sebally, K | 1 |
| Alkazemi, D | 1 |
| Lerch, A | 1 |
| Porter, N | 1 |
| Kubow, S | 1 |
| Papadopoulos, AS | 1 |
| Cleare, AJ | 2 |
| O'Keane, V | 1 |
| Miell, JP | 1 |
| Kodama, M | 1 |
| Kodama, T | 1 |
| Bentler, SE | 1 |
| Hartz, AJ | 1 |
| Kuhn, EM | 1 |
| Rook, GA | 1 |
| Zumla, A | 1 |
| Kuratsune, H | 1 |
| Yamaguti, K | 1 |
| Sawada, M | 1 |
| Kodate, S | 1 |
| Machii, T | 1 |
| Kanakura, Y | 1 |
| Kitani, T | 1 |
| De Becker, P | 1 |
| De Meirleir, K | 1 |
| Joos, E | 1 |
| Campine, I | 1 |
| Van Steenberge, E | 1 |
| Smitz, J | 1 |
| Velkeniers, B | 1 |
| Scott, LV | 2 |
| Salahuddin, F | 1 |
| Cooney, J | 1 |
| Svec, F | 2 |
| Dinan, TG | 1 |
| Dinan, T | 1 |
| van Rensburg, SJ | 1 |
| Potocnik, FC | 1 |
| Kiss, T | 1 |
| Hugo, F | 1 |
| van Zijl, P | 1 |
| Mansvelt, E | 1 |
| Carstens, ME | 1 |
| Theodorou, P | 1 |
| Hurly, PR | 1 |
| Emsley, RA | 1 |
| Taljaard, JJ | 1 |
1 review available for dehydroepiandrosterone and Fatigue Syndrome, Chronic
| Article | Year |
|---|---|
Hypothalamic-pituitary-adrenal axis dysfunction in chronic fatigue syndrome.
Topics: Dehydroepiandrosterone; Fatigue Syndrome, Chronic; Humans; Hydrocortisone; Hypothalamic Diseases; Hy | 2011 |
2 trials available for dehydroepiandrosterone and Fatigue Syndrome, Chronic
| Article | Year |
|---|---|
Levels of DHEA and DHEAS and responses to CRH stimulation and hydrocortisone treatment in chronic fatigue syndrome.
Topics: Adult; Area Under Curve; Body Mass Index; Corticotropin-Releasing Hormone; Cross-Over Studies; Dehyd | 2004 |
The clinical course of interstitial pneumonia alias chronic fatigue syndrome under the control of megadose vitamin C infusion system with dehydroepiandrosterone-cortisol annex.
Topics: Adult; Aged; Ascorbic Acid; Dehydroepiandrosterone; Depression; Fatigue Syndrome, Chronic; Female; F | 2005 |
8 other studies available for dehydroepiandrosterone and Fatigue Syndrome, Chronic
| Article | Year |
|---|---|
Increased HDAC in association with decreased plasma cortisol in older adults with chronic fatigue syndrome.
Topics: Aged; Aged, 80 and over; Antioxidants; Dehydroepiandrosterone; Fatigue Syndrome, Chronic; Female; Ge | 2011 |
Prospective observational study of treatments for unexplained chronic fatigue.
Topics: Adolescent; Adult; Aged; Antioxidants; Coenzymes; Complementary Therapies; Dehydroepiandrosterone; F | 2005 |
Gulf War syndrome: is it due to a systemic shift in cytokine balance towards a Th2 profile?
Topics: Affect; Animals; Cytokines; Dehydroepiandrosterone; Depressive Disorder; Fatigue Syndrome, Chronic; | 1997 |
Dehydroepiandrosterone sulfate deficiency in chronic fatigue syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Dehydroepiandrostero | 1998 |
Dehydroepiandrosterone (DHEA) response to i.v. ACTH in patients with chronic fatigue syndrome.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone; Fatigue Syndrome, Chroni | 1999 |
Differences in adrenal steroid profile in chronic fatigue syndrome, in depression and in health.
Topics: Adult; Dehydroepiandrosterone; Depressive Disorder, Major; Fatigue Syndrome, Chronic; Female; Health | 1999 |
A preliminary study of dehydroepiandrosterone response to low-dose ACTH in chronic fatigue syndrome and in healthy subjects.
Topics: Adrenocorticotropic Hormone; Adult; Analysis of Variance; Case-Control Studies; Dehydroepiandrostero | 2000 |
Serum concentrations of some metals and steroids in patients with chronic fatigue syndrome with reference to neurological and cognitive abnormalities.
Topics: Adult; Aluminum; Binding, Competitive; Cholesterol; Cognition Disorders; Copper; Dehydroepiandroster | 2001 |