dehydroepiandrosterone has been researched along with Experimental Neoplasms in 25 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Additionally, we examined the effects of intermittent dosing with DHEA." | 1.30 | Modulation of methylnitrosourea-induced breast cancer in Sprague Dawley rats by dehydroepiandrosterone: dose-dependent inhibition, effects of limited exposure, effects on peroxisomal enzymes, and lack of effects on levels of Ha-Ras mutations. ( Gordon, GB; Grubbs, CJ; Kelloff, GJ; Lei, XD; Lubet, RA; Moon, RD; Prough, RA; Steele, VE; Thomas, CF; Wang, Y; You, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (64.00) | 18.7374 |
| 1990's | 7 (28.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, HW | 1 |
| Peng, S | 1 |
| Gu, XZ | 1 |
| Chen, H | 1 |
| He, Y | 1 |
| Gao, W | 1 |
| Lv, F | 1 |
| Wang, JH | 1 |
| Wang, Y | 2 |
| Xie, J | 1 |
| Liu, MY | 1 |
| Yi, Z | 1 |
| Qiu, WW | 1 |
| QUERNER, H | 2 |
| WRBA, H | 2 |
| Mastrocola, R | 1 |
| Reffo, P | 1 |
| Penna, F | 1 |
| Tomasinelli, CE | 1 |
| Boccuzzi, G | 1 |
| Baccino, FM | 1 |
| Aragno, M | 1 |
| Costelli, P | 1 |
| Antila, E | 1 |
| Wartiovaara, J | 1 |
| Schwartz, AG | 6 |
| Tannen, RH | 1 |
| Shibata, M | 1 |
| Hasegawa, R | 1 |
| Imaida, K | 1 |
| Hagiwara, A | 1 |
| Ogawa, K | 1 |
| Hirose, M | 1 |
| Ito, N | 2 |
| Shirai, T | 1 |
| Pashko, LL | 4 |
| Orner, GA | 1 |
| Hendricks, JD | 1 |
| Arbogast, D | 1 |
| Williams, DE | 1 |
| Lubet, RA | 1 |
| Gordon, GB | 2 |
| Prough, RA | 1 |
| Lei, XD | 1 |
| You, M | 1 |
| Grubbs, CJ | 1 |
| Steele, VE | 1 |
| Kelloff, GJ | 1 |
| Thomas, CF | 1 |
| Moon, RD | 1 |
| Lemon, HM | 1 |
| Schwartz, A | 1 |
| Moore, MA | 1 |
| Thamavit, W | 1 |
| Tsuda, H | 1 |
| Shantz, LM | 1 |
| Talalay, P | 1 |
| Whitcomb, JM | 2 |
| Nyce, JW | 1 |
| Lewbart, ML | 1 |
| Nishino, H | 1 |
| Pashko, L | 1 |
| Lucis, OJ | 1 |
| Lucis, R | 1 |
| Maynard, PV | 2 |
| Cameron, EH | 2 |
| Miller, WR | 1 |
| Buchan, R | 1 |
| Forrest, AP | 1 |
| Mainwaring, WI | 1 |
| Mangan, FR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of DHEA on Skin Aging - Placebo-Controlled and Randomized Phase III Study in Postmenopausal Women.[NCT00248989] | Phase 3 | 150 participants (Actual) | Interventional | 2004-11-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for dehydroepiandrosterone and Experimental Neoplasms
| Article | Year |
|---|---|
Role of adrenocortical steroids in mediating cancer-preventive and age-retarding effects of food restriction in laboratory rodents.
Topics: Aging; Animals; Dehydroepiandrosterone; Food Deprivation; Glucocorticoids; Mice; Neoplasms, Experime | 1994 |
Mechanism of cancer preventive action of DHEA. Role of glucose-6-phosphate dehydrogenase.
Topics: Adrenalectomy; Animals; Dehydroepiandrosterone; Energy Intake; Female; Glucosephosphate Dehydrogenas | 1995 |
Modulation of growth, differentiation and carcinogenesis by dehydroepiandrosterone.
Topics: Adipose Tissue; Animals; Body Weight; Cell Differentiation; Cell Division; Dehydroepiandrosterone; D | 1987 |
Dehydroepiandrosterone and structural analogs: a new class of cancer chemopreventive agents.
Topics: Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Male; Neoplasms; Ne | 1988 |
Inhibition of tumor development by dehydroepiandrosterone and related steroids.
Topics: Animals; Dehydroepiandrosterone; Energy Intake; Glucosephosphate Dehydrogenase; Mice; Neoplasms, Exp | 1986 |
20 other studies available for dehydroepiandrosterone and Experimental Neoplasms
| Article | Year |
|---|---|
Synthesis and biological evaluation of D-ring fused 1,2,3-thiadiazole dehydroepiandrosterone derivatives as antitumor agents.
Topics: Androstenes; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Prolifera | 2016 |
[Effect of dehydroisoandrosterone acetate on neoplastic formation in Lebistes reticulatus Pet].
Topics: Acetates; Androgens; Animals; Carcinogens; Dehydroepiandrosterone; Neoplasms, Experimental; Poecilia | 1953 |
[Observations on the effects of the androgenic steroid hormone dehydroisoandrosterone in white rats].
Topics: Androgens; Animals; Biological Assay; Dehydroepiandrosterone; Infections; Neoplasms, Experimental; R | 1958 |
Muscle wasting in diabetic and in tumor-bearing rats: role of oxidative stress.
Topics: Animals; Dehydroepiandrosterone; Diabetes Mellitus, Experimental; DNA; Male; Muscular Atrophy; MyoD | 2008 |
Metabolism of steroids by mouse teratocarcinoma cells.
Topics: Androstenedione; Animals; Cells, Cultured; Dehydroepiandrosterone; Estradiol; Fibroblasts; Kinetics; | 1980 |
Inhibition of 7,12-dimethylbenz[a]anthracene- and urethan-induced lung tumor formation in A/J mice by long-term treatment with dehydroepiandrosterone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Body Weight; Dehydroepiandrosterone; | 1981 |
Chemoprevention by dehydroepiandrosterone and indomethacin in a rat multiorgan carcinogenesis model.
Topics: Animals; Anticarcinogenic Agents; Dehydroepiandrosterone; Disease Models, Animal; Hyperplasia; Indom | 1995 |
Inhibition of 7,12-dimethylbenz[a]anthracene-induced lung tumorigenesis in A/J mice by food restriction is reversed by adrenalectomy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Animals; Carcinogens; Corticosterone; Dehydroepiand | 1996 |
Modulation of N-methyl-N'-nitro-nitrosoguanidine multiorgan carcinogenesis by dehydroepiandrosterone in rainbow trout.
Topics: Animals; Carcinogens; Dehydroepiandrosterone; Kidney Neoplasms; Liver Neoplasms, Experimental; Methy | 1996 |
Clinical development plan: dehydroepiandrosterone (DHEA).
Topics: Aged; Animals; Anticarcinogenic Agents; Clinical Trials, Phase II as Topic; Dehydroepiandrosterone; | 1996 |
Modulation of methylnitrosourea-induced breast cancer in Sprague Dawley rats by dehydroepiandrosterone: dose-dependent inhibition, effects of limited exposure, effects on peroxisomal enzymes, and lack of effects on levels of Ha-Ras mutations.
Topics: Animals; Cell Division; Coenzyme A Ligases; Dehydroepiandrosterone; Diet; Dose-Response Relationship | 1998 |
Estriol prevention of mammary carcinoma induced by 7,12-dimethylbenzanthracene and procarbazine.
Topics: Animals; Benz(a)Anthracenes; Carcinogens; Castration; Corticosterone; Dehydroepiandrosterone; Estrad | 1975 |
The effects of dehydroepiandrosterone on the rate of development of cancer and autoimmune processes in laboratory rodents.
Topics: Animals; Carcinogens; Dehydroepiandrosterone; Diet, Reducing; Energy Intake; Glucosephosphate Dehydr | 1985 |
The influence of subsequent dehydroepiandrosterone, diaminopropane, phenobarbital, butylated hydroxyanisole and butylated hydroxytoluene treatment on the development of preneoplastic and neoplastic lesions in the rat initiated with di-hydroxy-di-n-propyl
Topics: Animals; Anisoles; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Carcinogens; Dehydroepiandros | 1986 |
[Mechanism of tumor promotion].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calmodulin; | 1988 |
Conversion of dehydroepiandrosterone, pregnenolone, and progesterone by interstitial cell tumor tissue.
Topics: Androstanes; Animals; Carbon Isotopes; Chromatography; Corticosterone; Dehydroepiandrosterone; Desox | 1970 |
Metabolism of C 19 steroids by homogenates of normal rat and mouse adrenal tissue, and of the Snell transplantable rat adrenocortical tumour 494.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androstanes; Androsterone; Animals; Carbon Isotopes; Choles | 1972 |
Metabolism of C 19 -steroids by homogenates of normal rat and mouse adrenal tissue and of the Snell transplantable rat adrenocortical tumour 494.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androstanes; Androsterone; Animals; Carbon Isotopes; Choles | 1972 |
Proceedings: The effects of fentazin on androgen metabolism in DMBA induced rat adenocarcinomata.
Topics: Adenocarcinoma; Androgens; Animals; Benz(a)Anthracenes; Dehydroepiandrosterone; Female; Neoplasms, E | 1974 |
A study of the androgen receptors in a variety of androgen-sensitive tissues.
Topics: Animals; Castration; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Ion Exchange; C | 1973 |