dehydroepiandrosterone has been researched along with Diabetes Mellitus in 43 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two metabolites of the adrenal steroid dehydroepiandrosterone (DHEA), 3 alpha-hydroxyetiocholanolone and 3 beta-hydroxyetiocholanolone, were found to have antiobesity properties with respect to both prevention of the development of obesity as well as weight reduction after obesity was established." | 7.67 | Antiobesity effects of etiocholanolones in diabetes (db), viable yellow (Avy), and normal mice. ( Coleman, DL, 1985) |
| " The author's own findings and the data available in the literature indicate that the androgens dehydroepiandrosterone and dehydroepiandrosterone sulfate that are secreted in the reticular area play an important role in ensuring the body's full stable adaptation to stress and simultaneously preventing stress-associated abnormalities, such as atherosclerosis, diabetes, immunodefficiency, hypertension, allergies, and cancer." | 4.80 | [Dehydroepiandrosterone, reticular area of adrenal cortex and resistance to stress and disease]. ( Obut, TA, 1998) |
| "Aldose reductase catalyzes the NADPH-linked reduction of hexoses to their respective sugar-alcohols, which are involved in the pathogenesis of "sugar-cataracts"." | 3.68 | Effects of G-6-PD deficiency, experimentally induced or genetically transmitted, on the sorbitol pathway activity. In vitro and in vivo studies. ( Alvarez, A; Chávez, M; Chávez-Anaya, E; Medina, C; Medina, MD; Mendoza, R; Ramírez, MG; Sáenz, G; Vaca, G; Vargas, M, 1992) |
| "Two metabolites of the adrenal steroid dehydroepiandrosterone (DHEA), 3 alpha-hydroxyetiocholanolone and 3 beta-hydroxyetiocholanolone, were found to have antiobesity properties with respect to both prevention of the development of obesity as well as weight reduction after obesity was established." | 3.67 | Antiobesity effects of etiocholanolones in diabetes (db), viable yellow (Avy), and normal mice. ( Coleman, DL, 1985) |
| "Obesity is an issue that is increasingly affecting ageing men." | 2.41 | Impact of obesity on hypogonadism in the andropause. ( Pu, SJ; Tan, RS, 2002) |
| " Therefore, the deleterious side-effects of chronic administration of GC emerges from both their direct catabolic activity and the suppression of DHEA production." | 2.40 | Should dehydroepiandrosterone replacement therapy be provided with glucocorticoids? ( Cutolo, M; Robinzon, B, 1999) |
| "Dehydroepiandrosterone was positively associated with IFG but not with diabetes." | 1.35 | Association of endogenous sex hormones with diabetes and impaired fasting glucose in men: multi-ethnic study of atherosclerosis. ( Colangelo, LA; Cushman, M; Dobs, AS; Gapstur, SM; Golden, SH; Kopp, P; Liu, K; Ouyang, P; Szklo, M; Vaidya, D, 2009) |
| "Despite hyperinsulinemia, the glucose production of db/db mice in the total body and hepatocytes was elevated as compared to their heterozygote littermate C57BL/KsJ-db/+m mice." | 1.32 | Dehydroepiandrosterone decreases elevated hepatic glucose production in C57BL/KsJ-db/db mice. ( Aoki, K; Ito, S; Ito, Y; Mori, Y; Muramatsu, K; Nakamura, S; Satoh, S; Sekihara, H; Taniguchi, H; Yamashita, R, 2004) |
| "Dehydroepiandrosterone (DHEA) was fed at 0." | 1.27 | Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes-obesity mutants and in aged normal mice. ( Coleman, DL; Leiter, EH; Schwizer, RW, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (41.86) | 18.7374 |
| 1990's | 10 (23.26) | 18.2507 |
| 2000's | 13 (30.23) | 29.6817 |
| 2010's | 2 (4.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, C | 1 |
| Golden, SH | 3 |
| Kong, S | 1 |
| Nan, B | 1 |
| Mather, KJ | 1 |
| Barrett-Connor, E | 1 |
| Colangelo, LA | 1 |
| Ouyang, P | 2 |
| Liu, K | 1 |
| Kopp, P | 1 |
| Dobs, AS | 2 |
| Szklo, M | 1 |
| Vaidya, D | 2 |
| Cushman, M | 1 |
| Gapstur, SM | 2 |
| Kalyani, RR | 1 |
| Franco, M | 1 |
| Bertoni, A | 1 |
| Baillot, A | 1 |
| Vibarel-Rebot, N | 1 |
| Thomasson, R | 1 |
| Jollin, L | 1 |
| Amiot, V | 1 |
| Emy, P | 1 |
| Collomp, K | 1 |
| Tan, RS | 1 |
| Pu, SJ | 1 |
| Okazaki, R | 1 |
| Shibata, M | 1 |
| Hayashi, T | 1 |
| Tanaka, H | 1 |
| Aoki, K | 4 |
| Nakajima, A | 2 |
| Mukasa, K | 3 |
| Osawa, E | 1 |
| Mori, Y | 2 |
| Sekihara, H | 4 |
| SONKA, J | 6 |
| GREGORVA, I | 1 |
| PAV, J | 2 |
| SKRHA, F | 1 |
| GREGOROVA, I | 2 |
| DENEVE, L | 1 |
| VERMEULEN, A | 1 |
| Taniguchi, H | 1 |
| Ito, Y | 1 |
| Satoh, S | 3 |
| Nakamura, S | 1 |
| Muramatsu, K | 1 |
| Yamashita, R | 1 |
| Ito, S | 2 |
| Morley, JE | 1 |
| Kim, MJ | 1 |
| Haren, MT | 1 |
| Medina, MC | 1 |
| Souza, LC | 1 |
| Caperuto, LC | 1 |
| Anhê, GF | 1 |
| Amanso, AM | 1 |
| Teixeira, VP | 1 |
| Bordin, S | 1 |
| Carpinelli, AR | 1 |
| Britto, LR | 1 |
| Barbieri, RL | 1 |
| Borella, MI | 1 |
| Carvalho, CR | 1 |
| Alasandro, M | 1 |
| Wiesler, D | 1 |
| Rhodes, G | 1 |
| Novotny, M | 1 |
| Coleman, DL | 2 |
| Schwizer, RW | 1 |
| Leiter, EH | 1 |
| Andò, S | 1 |
| Rubens, R | 1 |
| Rottiers, R | 1 |
| Vidal-Puig, A | 1 |
| García-Calvente, C | 1 |
| Muñoz Torres, M | 1 |
| Svacina, S | 2 |
| Haas, T | 1 |
| Assan, R | 1 |
| Robel, P | 1 |
| Baulieu, EE | 1 |
| Yamauchi, A | 1 |
| Takei, I | 1 |
| Nakamoto, S | 1 |
| Ohashi, N | 1 |
| Kitamura, Y | 1 |
| Tokui, M | 1 |
| Nakano, S | 1 |
| Takayama, S | 1 |
| Kasuga, A | 1 |
| Katsukawa, F | 1 |
| Saruta, T | 1 |
| Obut, TA | 1 |
| Wellman, M | 1 |
| Shane-McWhorter, L | 1 |
| Jennings, JP | 1 |
| Robinzon, B | 1 |
| Cutolo, M | 1 |
| Saito, T | 1 |
| Kaneshiro, M | 1 |
| Kawasaki, S | 1 |
| Okamura, A | 2 |
| Nedĕlníková, K | 1 |
| Matoulek, M | 1 |
| Kikuchi, T | 1 |
| Byrne, JJ | 1 |
| Bradlow, HL | 1 |
| Bener, A | 1 |
| Lestringant, GG | 1 |
| Townsend, A | 1 |
| Al-Mulla, HM | 1 |
| Zdrojewicz, Z | 1 |
| Kesik, S | 1 |
| Szpunar, WE | 1 |
| Blair, AJ | 1 |
| McCann, DS | 1 |
| Gabbe, SG | 1 |
| Hagerman, DD | 1 |
| Vaca, G | 1 |
| Ramírez, MG | 1 |
| Vargas, M | 1 |
| Mendoza, R | 1 |
| Chávez-Anaya, E | 1 |
| Medina, MD | 1 |
| Alvarez, A | 1 |
| Medina, C | 1 |
| Sáenz, G | 1 |
| Chávez, M | 1 |
| Nestler, JE | 1 |
| McClanahan, MA | 1 |
| Higuchi, N | 1 |
| Sasaki, M | 1 |
| Arai, T | 1 |
| Oki, Y | 1 |
| Regelson, W | 1 |
| Loria, R | 1 |
| Kalimi, M | 1 |
| Charvát, J | 1 |
| Krese, A | 1 |
| de Moor, P | 1 |
| Heyns, W | 1 |
| Steeno, O | 1 |
| Faerman, I | 1 |
| Vilar, O | 1 |
| Rivarola, MA | 1 |
| Rosner, JM | 1 |
| Jadzinsky, MN | 1 |
| Fox, D | 1 |
| Lloret, AP | 1 |
| Bernstein-Hahn, L | 1 |
| Saraceni, D | 1 |
| Lauritzen, C | 1 |
| Holzmann, H | 1 |
| Hoede, N | 1 |
13 reviews available for dehydroepiandrosterone and Diabetes Mellitus
| Article | Year |
|---|---|
Impact of obesity on hypogonadism in the andropause.
Topics: Aged; Aging; Body Composition; Climacteric; Dehydroepiandrosterone; Diabetes Mellitus; Humans; Hypog | 2002 |
[Endocrine disorders in diabetes mellitus].
Topics: Animals; Bone and Bones; Bone Density; Calcium; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfa | 2002 |
Prevention of diabetes, hepatic injury, and colon cancer with dehydroepiandrosterone.
Topics: Aging; Animals; Colonic Neoplasms; Dehydroepiandrosterone; Diabetes Mellitus; Gluconeogenesis; Human | 2003 |
Frailty and hormones.
Topics: Aged; Cachexia; Cytokines; Dehydroepiandrosterone; Diabetes Mellitus; Frail Elderly; Hormones; Human | 2005 |
[Adrenal androgens: traditionally forgotten hormones. Today, of current importance].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Cardiovascular Diseases; Dehydroepiandroster | 1993 |
Dehydroepiandrosterone (DHEA) for diabetic patients?
Topics: Dehydroepiandrosterone; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Insulin; Obesity | 1996 |
[Dehydroepiandrosterone, reticular area of adrenal cortex and resistance to stress and disease].
Topics: Adjuvants, Immunologic; Animals; Arteriosclerosis; Dehydroepiandrosterone; Dehydroepiandrosterone Su | 1998 |
The role of dehydroepiandrosterone in diabetes mellitus.
Topics: Clinical Trials as Topic; Dehydroepiandrosterone; Diabetes Mellitus; Humans; Sex Factors | 1999 |
Should dehydroepiandrosterone replacement therapy be provided with glucocorticoids?
Topics: Adjuvants, Immunologic; Atrophy; Autoimmunity; Dehydroepiandrosterone; Diabetes Mellitus; Female; Gl | 1999 |
[Dehydroepiandrosterone (DHEA)--youth hormone?].
Topics: Aging; Arteriosclerosis; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes | 2001 |
Diabetes and adrenal disease.
Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Animals; Cushing Syndrome; Dehydroepiandrosterone; | 1992 |
Hormonal intervention: "buffer hormones" or "state dependency". The role of dehydroepiandrosterone (DHEA), thyroid hormone, estrogen and hypophysectomy in aging.
Topics: Aging; Animals; Cell Transformation, Neoplastic; Dehydroepiandrosterone; Diabetes Mellitus; Estrogen | 1988 |
[Current views on the psoriasis problem].
Topics: Amyloidosis; Arthritis; Celiac Disease; Cholesterol; Dehydroepiandrosterone; Diabetes Complications; | 1972 |
30 other studies available for dehydroepiandrosterone and Diabetes Mellitus
| Article | Year |
|---|---|
Does hormone therapy affect blood pressure changes in the Diabetes Prevention Program?
Topics: Blood Pressure; Body Weight; Dehydroepiandrosterone; Diabetes Mellitus; Estradiol; Estrogen Replacem | 2014 |
Association of endogenous sex hormones with diabetes and impaired fasting glucose in men: multi-ethnic study of atherosclerosis.
Topics: Aged; Aged, 80 and over; Atherosclerosis; Body Mass Index; Cohort Studies; Dehydroepiandrosterone; D | 2009 |
The association of endogenous sex hormones, adiposity, and insulin resistance with incident diabetes in postmenopausal women.
Topics: Adipose Tissue; Adiposity; Aged; Aged, 80 and over; Blood Glucose; Cohort Studies; Dehydroepiandrost | 2009 |
Serum and saliva adrenocortical hormones in obese diabetic men during submaximal exercise.
Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes Mellitus; Exercise; Humans; Hydroco | 2011 |
DEHYDROEPIANDROSTERONE IN OBESE DIABETICS.
Topics: Dehydroepiandrosterone; Diabetes Mellitus; Geriatrics; Humans; Lipid Metabolism; Obesity; Urine | 1964 |
DEHYDROEPIANDROSTERONE IN OBESE DIABETICS AFTER CORTICOTROPHIN STIMULATION.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Dehydroepiandrosterone; Diabetes Mellitus; Fluids and | 1965 |
THE DETERMINATION OF 17-OXOSTEROID SULPHATES IN HUMAN PLASMA.
Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenalectomy; Androsterone; Blood Chemical Analysis; | 1965 |
Dehydroepiandrosterone decreases elevated hepatic glucose production in C57BL/KsJ-db/db mice.
Topics: Adjuvants, Immunologic; Animals; Blood Glucose; Body Weight; Cells, Cultured; Dehydroepiandrosterone | 2004 |
Dehydroepiandrosterone increases beta-cell mass and improves the glucose-induced insulin secretion by pancreatic islets from aged rats.
Topics: Adjuvants, Immunologic; Aging; Animals; Cell Size; Dehydroepiandrosterone; Diabetes Mellitus; Humans | 2006 |
Quantitative alterations of steroid urinary profiles associated with diabetes mellitus.
Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Androsterone; Cholestanols; Dehyd | 1982 |
Effect of genetic background on the therapeutic effects of dehydroepiandrosterone (DHEA) in diabetes-obesity mutants and in aged normal mice.
Topics: Aging; Animals; Blood Glucose; Body Weight; Dehydroepiandrosterone; Diabetes Mellitus; Female; Gluco | 1984 |
Androgen plasma levels in male diabetics.
Topics: Adult; Aging; Androgens; Dehydroepiandrosterone; Diabetes Complications; Diabetes Mellitus; Erectile | 1984 |
Dehydroepiandrosterone and insulinaemia.
Topics: Arteriosclerosis; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes Mellitus; Humans; | 1995 |
Hyperglycemia decreases dehydroepiandrosterone in Japanese male with impaired glucose tolerance and low insulin response.
Topics: Dehydroepiandrosterone; Diabetes Mellitus; Glucose Intolerance; Glucose Tolerance Test; Humans; Hype | 1996 |
Dehydroepiandrosterone suppresses the elevated hepatic glucose-6-phosphatase and fructose-1,6-bisphosphatase activities in C57BL/Ksj-db/db mice: comparison with troglitazone.
Topics: Androstenedione; Animals; Blood Glucose; Body Composition; Chromans; Dehydroepiandrosterone; Diabete | 1999 |
[Metabolic and hormonal links in obese individuals with and without symptoms of syndrome X].
Topics: Arteriosclerosis; Dehydroepiandrosterone; Diabetes Mellitus; Humans; Insulin Resistance; Lipids; Obe | 2000 |
Dehydroepiandrosterone suppresses elevated hepatic glucose-6-phosphatase mRNA level in C57BL/KsJ-db/db mice: comparison with troglitazone.
Topics: Animals; Blood Glucose; Blotting, Northern; Body Weight; Chromans; Dehydroepiandrosterone; Diabetes | 2000 |
DHEA-PC slows the progression of type 2 diabetes (non-insulin-dependent diabetes mellitus) in the ZDF/Gmi-fa/fa rat.
Topics: Animals; Blood Glucose; Dehydroepiandrosterone; Diabetes Mellitus; Diabetes Mellitus, Type 2; Drug C | 2001 |
Association of acanthosis nigricans with risk of diabetes mellitus, and hormonal disturbances in arabian females: case-control study.
Topics: Acanthosis Nigricans; Adolescent; Adult; Aged; Aldosterone; Blood Glucose; Blood Pressure; Body Mass | 2001 |
Plasma androgen concentrations in diabetic women.
Topics: Adult; Age Factors; Androgens; Androstenedione; Dehydroepiandrosterone; Diabetes Complications; Diab | 1977 |
Clinical application of estriol analysis.
Topics: Dehydroepiandrosterone; Diabetes Mellitus; Estriol; Female; Fetal Diseases; Fetal Growth Retardation | 1978 |
Effects of G-6-PD deficiency, experimentally induced or genetically transmitted, on the sorbitol pathway activity. In vitro and in vivo studies.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Aldehyde Reductase; Animals; Black People | 1992 |
[Effect of androgen on the onset of diabetes in the KK mice treated with monosodium aspartate].
Topics: Age Factors; Androgens; Animals; Aspartic Acid; Blood Glucose; Castration; Dehydroepiandrosterone; D | 1989 |
Antiobesity effects of etiocholanolones in diabetes (db), viable yellow (Avy), and normal mice.
Topics: Animals; Blood Glucose; Body Weight; Dehydroepiandrosterone; Diabetes Mellitus; Diabetes Mellitus, E | 1985 |
The role of dehydroepiandrosterone in the regulation of metabolism and pathogenesis of certain diseases.
Topics: Dehydroepiandrosterone; Diabetes Mellitus; Glucosephosphate Dehydrogenase Deficiency; Humans | 1967 |
[Steroid spectrum of diabetic men in relationship to their potency].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Androsterone; Cortisone; Dehydroepiandrosterone; | 1966 |
Clinical and biochemical features associated with extreme CBC-values; possible significance of these associations.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Androsterone; Blood Protein | 1968 |
Impotence and diabetes. Studies of androgenic function in diabetic impotent males.
Topics: 17-Ketosteroids; Adult; Androgens; Androsterone; Chorionic Gonadotropin; Dehydroepiandrosterone; Dia | 1972 |
Conversion of DHEA-sulfate to estrogens as a test of placental function.
Topics: Dehydroepiandrosterone; Diabetes Mellitus; Erythroblastosis, Fetal; Estrogens; Female; Humans; Place | 1969 |
The role of DHA in the pathogenesis of obesity and its metabolic complications.
Topics: Amino Acids; Arteriosclerosis; Cholesterol; Dehydroepiandrosterone; Diabetes Mellitus; Fatty Acids; | 1969 |