dehydroepiandrosterone has been researched along with Diabetes Mellitus, Type 2 in 58 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dehydroepiandrosterone (DHEA), a steroid hormone produced by the adrenal cortex, has been reported to have beneficial effects on diabetes mellitus and obesity in animal models." | 8.98 | Effect of Dehydroepiandrosterone (DHEA) on Diabetes Mellitus and Obesity. ( Aoki, K; Terauchi, Y, 2018) |
| "This cross-sectional study assessed the association of serum dehydroepiandrosterone levels with the risk of diabetic retinopathy in patients with type 2 diabetes mellitus in China." | 8.31 | Low serum dehydroepiandrosterone levels are associated with diabetic retinopathy in patients with type 2 diabetes mellitus. ( Feng, W; Huang, Y; Liu, M; Qiao, J; Xu, N; Zhang, X, 2023) |
| "In hyperandrogenic females, the ratio of dehydroepiandrosterone (DHEA) to testosterone may be an important determinant of insulin sensitivity." | 7.68 | Case report: amelioration of insulin resistance in diabetes with dehydroepiandrosterone. ( Buffington, CK; Kitabchi, AE; Pourmotabbed, G, 1993) |
| "Non-classic congenital adrenal hyperplasia (NC-CAH), one of the most common genetic disorders, is often associated with the clinical features of hyperandrogenism." | 5.40 | The effect of metformin on androgen production in diabetic women with non-classic congenital adrenal hyperplasia. ( Krysiak, R; Okopien, B, 2014) |
| " Dehydroepiandrosterone (DHEA), a steroid hormone produced by the adrenal cortex, has been reported to have beneficial effects on diabetes mellitus and obesity in animal models." | 4.98 | Effect of Dehydroepiandrosterone (DHEA) on Diabetes Mellitus and Obesity. ( Aoki, K; Terauchi, Y, 2018) |
| "This cross-sectional study assessed the association of serum dehydroepiandrosterone levels with the risk of diabetic retinopathy in patients with type 2 diabetes mellitus in China." | 4.31 | Low serum dehydroepiandrosterone levels are associated with diabetic retinopathy in patients with type 2 diabetes mellitus. ( Feng, W; Huang, Y; Liu, M; Qiao, J; Xu, N; Zhang, X, 2023) |
| "The aim of this study was to investigate the effects of berberine on polycystic ovary syndrome (PCOS) with insulin resistance (IR)." | 4.02 | Berberine Improves the Symptoms of DHEA-Induced PCOS Rats by Regulating Gut Microbiotas and Metabolites. ( Li, XL; Shen, HR; Xu, X; Ye, D, 2021) |
| "Dehydroepiandrosterone exerts a protective effect against cardiovascular diseases." | 3.78 | Correlation of circulating dehydroepiandrosterone with activated protein C generation and carotid intima-media thickness in male patients with type 2 diabetes. ( Akatsuka, H; Gabazza, EC; Hayashi, T; Maruyama-Furuta, N; Matsumoto, K; Onishi, Y; Sakamoto, M; Sasaki, R; Sumida, Y; Suzuki, T; Takei, Y; Uemura, M; Yano, Y; Yasuma, T, 2012) |
| "Dehydroepiandrosterone (DHEA) is believed to exert, besides others, positive effects on the insulin resistance or its secretion and glucose metabolism." | 3.78 | Dehydroepiandrosterone in the type 1 diabetes mellitus. ( Duskova, M; Hill, M; Hruskovicova, H; Starka, L, 2012) |
| " Dehydroepiandrosterone (DHEA) and AA, like the thiazolidinedione drugs that decrease insulin resistance (IR), are peroxisome proliferators." | 3.71 | Dehydroepiandrosterone alters phospholipid profiles in Zucker rat muscle tissue. ( Abadie, JM; Malcom, GT; Porter, JR; Svec, F, 2001) |
| "In hyperandrogenic females, the ratio of dehydroepiandrosterone (DHEA) to testosterone may be an important determinant of insulin sensitivity." | 3.68 | Case report: amelioration of insulin resistance in diabetes with dehydroepiandrosterone. ( Buffington, CK; Kitabchi, AE; Pourmotabbed, G, 1993) |
| "Dehydroepiandrosterone (DHEA) has been shown to prevent oxidative stress in several in vivo and in vitro models." | 2.73 | Dehydroepiandrosterone administration counteracts oxidative imbalance and advanced glycation end product formation in type 2 diabetic patients. ( Aragno, M; Boccuzzi, G; Brignardello, E; Cassader, M; Catalano, MG; Perin, PC; Runzo, C, 2007) |
| "We studied 130 patients with type 2 diabetes mellitus (74 men and 56 women between the ages of 40 and 69 years), whose blood glucose control had been poor (more than 10% in HbA(1c))." | 2.70 | Decreased steroidogenic enzyme 17,20-lyase and increased 17-hydroxylase activities in type 2 diabetes mellitus. ( Hiroi, N; Miyachi, Y; Shimizu, Y; Shimojo, M; Tsuboi, K; Ueshiba, H; Yakushiji, F, 2002) |
| "In women with Type 2 diabetes following a high-CHO diet for 12 weeks the disproportionate loss of lower body fat is related to a decline in DHEAS." | 2.69 | Dietary composition affects regional body fat distribution and levels of dehydroepiandrosterone sulphate (DHEAS) in post-menopausal women with Type 2 diabetes. ( Nicholson, GC; O'Dea, K; Walker, KZ, 1999) |
| "Type 2 diabetes mellitus is increasing globally and is an established risk factor for the development of atherosclerotic vascular disease." | 2.43 | Androgens, insulin resistance and vascular disease in men. ( Channer, KS; Jones, TH; Kapoor, D; Malkin, CJ, 2005) |
| "Hypogonadism was associated with decreased levels of a number of testosterone precursors." | 1.72 | [Features of steroidogenesis in men with hypogonadism and type 2 diabetes]. ( Chernova, MO; Ioutsi, VA; Mel'nichenko, GA; Mokrysheva, NG; Rozhivanov, RV; Shestakova, MV, 2022) |
| "Type 2 diabetes is clinically associated with progressive necroinflammation and fibrosis in nonalcoholic steatohepatitis (NASH)." | 1.56 | AGER1 downregulation associates with fibrosis in nonalcoholic steatohepatitis and type 2 diabetes. ( Ali, M; Charville, GW; Das, S; Dehnad, A; Fan, W; Fish, SR; Jiang, JX; Li, Y; Mozes, G; Olson, KA; Török, NJ; Wong, KA, 2020) |
| "A total of 4720 participants with type 2 diabetes were recruited from Shanghai, China." | 1.51 | Novel associations between sex hormones and diabetic vascular complications in men and postmenopausal women: a cross-sectional study. ( Chen, Y; Lu, Y; Wan, H; Wang, C; Wang, N; Wang, Y; Xia, F; Zhang, K; Zhang, W, 2019) |
| "Androstenedione was not associated with risk of type 2 diabetes, nor was DHEAS to DHEA ratio." | 1.46 | Serum dehydroepiandrosterone levels are associated with lower risk of type 2 diabetes: the Rotterdam Study. ( Brahimaj, A; Dehghan, A; Franco, OH; Kavousi, M; Laven, JS; Muka, T, 2017) |
| "Non-classic congenital adrenal hyperplasia (NC-CAH), one of the most common genetic disorders, is often associated with the clinical features of hyperandrogenism." | 1.40 | The effect of metformin on androgen production in diabetic women with non-classic congenital adrenal hyperplasia. ( Krysiak, R; Okopien, B, 2014) |
| "Platelets in patients with type 2 diabetes (T2D) are more sensitive to aggregation, which has been attributed to a reduced ability to produce nitric oxide (NO)." | 1.38 | Dehydroepiandrosterone prevents the aggregation of platelets obtained from postmenopausal women with type 2 diabetes mellitus through the activation of the PKC/eNOS/NO pathway. ( Gomez, GI; Moreno, M; Muñoz, YC; Solis, CL; Valladares, LE; Velarde, V, 2012) |
| "Dehydroepiandrosterone was higher in the luteal phase in probands than controls." | 1.30 | Insulin sensitivity and sex steroid hormone levels during the menstrual cycle in healthy women with non-insulin-dependent diabetic parents. ( González-Ortiz, M; Lifshitz, A; Martínez-Abundis, E, 1998) |
| "However, PCO patients with NIDDM differed from those without diabetes in that they had elevated basal and corticotropin-stimulated adrenal steroids (cortisol, dehydroepiandrosterone [DHEA], dehydroepiandrosterone sulfate [DHEAS])." | 1.29 | Enhanced adrenocortical activity as a contributing factor to diabetes in hyperandrogenic women. ( Buffington, CK; Givens, JR; Kitabchi, AE, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.72) | 18.7374 |
| 1990's | 13 (22.41) | 18.2507 |
| 2000's | 19 (32.76) | 29.6817 |
| 2010's | 17 (29.31) | 24.3611 |
| 2020's | 8 (13.79) | 2.80 |
| Authors | Studies |
|---|---|
| Shen, HR | 1 |
| Xu, X | 1 |
| Ye, D | 1 |
| Li, XL | 1 |
| Ma, Y | 1 |
| Wang, Q | 1 |
| Chen, Y | 2 |
| Su, J | 1 |
| Gao, Q | 1 |
| Fan, Y | 1 |
| Feng, J | 1 |
| Liu, M | 3 |
| He, Q | 2 |
| Zhang, X | 2 |
| Xiao, J | 1 |
| Li, X | 1 |
| Cui, J | 1 |
| Wang, K | 1 |
| Rozhivanov, RV | 1 |
| Chernova, MO | 1 |
| Ioutsi, VA | 1 |
| Mel'nichenko, GA | 1 |
| Shestakova, MV | 1 |
| Mokrysheva, NG | 1 |
| Benko, F | 1 |
| Chomová, M | 1 |
| Uličná, O | 1 |
| Ďuračka, M | 1 |
| Kováč, J | 1 |
| Tvrdá, E | 1 |
| Huang, Y | 1 |
| Xu, N | 1 |
| Feng, W | 1 |
| Qiao, J | 1 |
| Offei, SD | 1 |
| Arman, HD | 1 |
| Yoshimoto, FK | 1 |
| Dehnad, A | 1 |
| Fan, W | 1 |
| Jiang, JX | 1 |
| Fish, SR | 1 |
| Li, Y | 1 |
| Das, S | 1 |
| Mozes, G | 1 |
| Wong, KA | 1 |
| Olson, KA | 1 |
| Charville, GW | 1 |
| Ali, M | 1 |
| Török, NJ | 1 |
| Li, W | 1 |
| Li, SJ | 1 |
| Yin, TL | 1 |
| Yang, J | 1 |
| Cheng, Y | 1 |
| Blaslov, K | 1 |
| Kruljac, I | 1 |
| Mirošević, G | 1 |
| Kirigin Biloš, LS | 1 |
| Vrkljan, M | 1 |
| Aoki, K | 2 |
| Terauchi, Y | 2 |
| Wang, C | 1 |
| Zhang, W | 1 |
| Wang, Y | 1 |
| Wan, H | 1 |
| Xia, F | 1 |
| Zhang, K | 1 |
| Wang, N | 1 |
| Lu, Y | 1 |
| Kim, C | 1 |
| Halter, JB | 1 |
| Krysiak, R | 1 |
| Okopien, B | 1 |
| Racaru-Honciuc, V | 1 |
| Betea, D | 1 |
| Scheen, AJ | 1 |
| Tajima, K | 1 |
| Taguri, M | 1 |
| Brahimaj, A | 1 |
| Muka, T | 1 |
| Kavousi, M | 1 |
| Laven, JS | 1 |
| Dehghan, A | 1 |
| Franco, OH | 1 |
| Sato, K | 1 |
| Fujita, S | 1 |
| Iemitsu, M | 1 |
| Diamanti-Kandarakis, E | 1 |
| Dattilo, M | 1 |
| Macut, D | 1 |
| Duntas, L | 1 |
| Gonos, ES | 1 |
| Goulis, DG | 1 |
| Gantenbein, CK | 1 |
| Kapetanou, M | 1 |
| Koukkou, E | 1 |
| Lambrinoudaki, I | 1 |
| Michalaki, M | 1 |
| Eftekhari-Nader, S | 1 |
| Pasquali, R | 1 |
| Peppa, M | 1 |
| Tzanela, M | 1 |
| Vassilatou, E | 1 |
| Vryonidou, A | 1 |
| Subasinghe, W | 2 |
| Spence, DM | 1 |
| Gupte, RS | 1 |
| Floyd, BC | 1 |
| Kozicky, M | 1 |
| George, S | 1 |
| Ungvari, ZI | 1 |
| Neito, V | 1 |
| Wolin, MS | 1 |
| Gupte, SA | 1 |
| Kim, NN | 1 |
| Kanat, M | 1 |
| Serin, E | 1 |
| Tunckale, A | 1 |
| Yildiz, O | 1 |
| Sahin, S | 1 |
| Bolayirli, M | 1 |
| Arinc, H | 1 |
| Dirican, A | 1 |
| Karagoz, Y | 1 |
| Altuntas, Y | 1 |
| Celebi, H | 1 |
| Oguz, A | 1 |
| Kalyani, RR | 1 |
| Franco, M | 1 |
| Dobs, AS | 1 |
| Ouyang, P | 1 |
| Vaidya, D | 1 |
| Bertoni, A | 1 |
| Gapstur, SM | 1 |
| Golden, SH | 1 |
| Felšöci, M | 1 |
| Schroner, Z | 1 |
| Petrovičová, J | 1 |
| Lazúrová, I | 1 |
| Baillot, A | 1 |
| Vibarel-Rebot, N | 1 |
| Amiot, V | 1 |
| Emy, P | 1 |
| Collomp, K | 1 |
| Suzuki, T | 1 |
| Yano, Y | 1 |
| Sakamoto, M | 1 |
| Uemura, M | 1 |
| Yasuma, T | 1 |
| Onishi, Y | 1 |
| Sasaki, R | 1 |
| Matsumoto, K | 1 |
| Hayashi, T | 1 |
| Maruyama-Furuta, N | 1 |
| Akatsuka, H | 1 |
| Gabazza, EC | 1 |
| Sumida, Y | 1 |
| Takei, Y | 1 |
| Reading, CL | 1 |
| Frincke, JM | 1 |
| White, SK | 1 |
| Muñoz, YC | 1 |
| Gomez, GI | 1 |
| Moreno, M | 1 |
| Solis, CL | 1 |
| Valladares, LE | 1 |
| Velarde, V | 1 |
| Duskova, M | 1 |
| Hruskovicova, H | 1 |
| Hill, M | 1 |
| Starka, L | 1 |
| Tagawa, N | 1 |
| Ohta, M | 1 |
| Nakamura, N | 1 |
| Nakano, K | 1 |
| Obayashi, H | 1 |
| Kobayashi, Y | 1 |
| Kapoor, D | 1 |
| Malkin, CJ | 1 |
| Channer, KS | 1 |
| Jones, TH | 1 |
| Carroll, J | 1 |
| Raththagala, M | 1 |
| Baguzis, S | 1 |
| D'amico Oblak, T | 1 |
| Root, P | 1 |
| Spence, D | 1 |
| Zhang, YF | 1 |
| Yang, YS | 1 |
| Hong, J | 1 |
| Gu, WQ | 1 |
| Shen, CF | 1 |
| Xu, M | 1 |
| Du, PF | 1 |
| Li, XY | 1 |
| Ning, G | 1 |
| Bácsi, K | 1 |
| Kósa, J | 1 |
| Lazáry, A | 1 |
| Horváth, H | 1 |
| Balla, B | 1 |
| Lakatos, P | 1 |
| Speer, G | 1 |
| Brignardello, E | 1 |
| Runzo, C | 1 |
| Aragno, M | 1 |
| Catalano, MG | 1 |
| Cassader, M | 1 |
| Perin, PC | 1 |
| Boccuzzi, G | 1 |
| Clark, DG | 1 |
| Tomas, FM | 1 |
| Withers, RT | 1 |
| Brinkman, M | 1 |
| Berry, MN | 1 |
| Oliver, JR | 1 |
| Owens, PC | 1 |
| Butler, RN | 1 |
| Ballard, FJ | 1 |
| Nestel, PJ | 1 |
| Buffington, CK | 2 |
| Givens, JR | 1 |
| Kitabchi, AE | 2 |
| Pourmotabbed, G | 1 |
| Parente, JA | 1 |
| Berdanier, CD | 1 |
| Nestler, JE | 1 |
| Barrett-Connor, E | 2 |
| Ferrara, A | 1 |
| Assan, R | 1 |
| Robel, P | 1 |
| Baulieu, EE | 1 |
| Yamauchi, A | 1 |
| Takei, I | 1 |
| Kasuga, A | 1 |
| Kitamura, Y | 1 |
| Ohashi, N | 1 |
| Nakano, S | 1 |
| Takayama, S | 1 |
| Nakamoto, S | 1 |
| Katsukawa, F | 1 |
| Saruta, T | 1 |
| González-Ortiz, M | 1 |
| Martínez-Abundis, E | 1 |
| Lifshitz, A | 1 |
| Yamaguchi, Y | 1 |
| Tanaka, S | 1 |
| Yamakawa, T | 1 |
| Kimura, M | 1 |
| Ukawa, K | 1 |
| Yamada, Y | 1 |
| Ishihara, M | 1 |
| Sekihara, H | 1 |
| Walker, KZ | 1 |
| O'Dea, K | 1 |
| Nicholson, GC | 1 |
| Brabant, G | 1 |
| von zur Mühlen, A | 1 |
| Boudou, P | 2 |
| De Kerviler, E | 2 |
| Vexiau, P | 2 |
| Fiet, J | 1 |
| Cathelineau, G | 1 |
| Gautier, J | 1 |
| Zietz, B | 1 |
| Watzlawek, E | 1 |
| Palitzsch, KD | 1 |
| Schölmerich, J | 1 |
| Schäffler, A | 1 |
| Erlich, D | 1 |
| Gautier, JF | 1 |
| Byrne, JJ | 1 |
| Bradlow, HL | 1 |
| Schwartz, AG | 1 |
| Pashko, LL | 1 |
| Abadie, JM | 1 |
| Malcom, GT | 1 |
| Porter, JR | 1 |
| Svec, F | 1 |
| Ueshiba, H | 1 |
| Shimizu, Y | 1 |
| Hiroi, N | 1 |
| Yakushiji, F | 1 |
| Shimojo, M | 1 |
| Tsuboi, K | 1 |
| Miyachi, Y | 1 |
| Amemiya, T | 1 |
| Kawahara, R | 1 |
| Yoshino, M | 1 |
| Komori, K | 1 |
| Hirata, Y | 1 |
| Sackett-Lundeen, L | 1 |
| Nicolau, GY | 1 |
| Lakatua, DJ | 1 |
| Bogdan, C | 1 |
| Petrescu, E | 1 |
| Jachimowicz, A | 1 |
| Haus, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Antioxidants vs.Ovarian Bio-stimulation Therapy to Rescue the Ovarian Reserve[NCT03621683] | 78 participants (Actual) | Interventional | 2016-01-06 | Completed | |||
| Role of Gonadotropin Pulsations in the Reversal of Hypogonadotropic Hypogonadism[NCT00392756] | Phase 1 | 624 participants (Actual) | Interventional | 1989-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for dehydroepiandrosterone and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Effect of Dehydroepiandrosterone (DHEA) on Diabetes Mellitus and Obesity.
Topics: Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes Mellitus, Type 2; Humans; | 2018 |
Endogenous sex hormones, metabolic syndrome, and diabetes in men and women.
Topics: Age Factors; Androgens; Biomarkers; Blood Glucose; Cross-Sectional Studies; Dehydroepiandrosterone; | 2014 |
MECHANISMS IN ENDOCRINOLOGY: Aging and anti-aging: a Combo-Endocrinology overview.
Topics: Adjuvants, Immunologic; Aging; Androgens; Antioxidants; Circadian Rhythm; Dehydroepiandrosterone; Di | 2017 |
Sex steroid hormones in diabetes-induced sexual dysfunction: focus on the female gender.
Topics: Clitoris; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Estrogens; Female; Glucose Intolerance; | 2009 |
Androgens, insulin resistance and vascular disease in men.
Topics: Aged; Aging; Arteriosclerosis; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Humans; Insulin Re | 2005 |
[Significance of dehydroepiandrosterone and dehydroepiandrosterone sulfate in different diseases].
Topics: Androgens; Cardiovascular Diseases; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes | 2007 |
Dehydroepiandrosterone (DHEA) for diabetic patients?
Topics: Dehydroepiandrosterone; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Insulin; Obesity | 1996 |
[Endocrine and metabolic functional disorders in extreme old age].
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Clinical Trials as Topic; Dehydroepiandrosterone; Diabe | 2000 |
Potential therapeutic use of dehydroepiandrosterone and structural analogs.
Topics: Animals; Dehydroepiandrosterone; Diabetes Mellitus, Type 2 | 2001 |
7 trials available for dehydroepiandrosterone and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
A multi-center, open label, crossover designed prospective study evaluating the effects of lipid lowering treatment on steroid synthesis in patients with Type 2 diabetes (MODEST Study).
Topics: Adult; Analysis of Variance; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; C | 2009 |
Dehydroepiandrosterone administration counteracts oxidative imbalance and advanced glycation end product formation in type 2 diabetic patients.
Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes Mellitus, Type 2; Double-Blind Meth | 2007 |
Differences in substrate metabolism between self-perceived 'large-eating' and 'small-eating' women.
Topics: Adult; Appetite; Basal Metabolism; Calorimetry, Indirect; Carbon Dioxide; Dehydroepiandrosterone; De | 1995 |
Dietary composition affects regional body fat distribution and levels of dehydroepiandrosterone sulphate (DHEAS) in post-menopausal women with Type 2 diabetes.
Topics: Adipose Tissue; Adjuvants, Immunologic; Blood Glucose; Body Composition; Cholesterol Esters; Cross-O | 1999 |
Effects of a single bout of exercise and exercise training on steroid levels in middle-aged type 2 diabetic men: relationship to abdominal adipose tissue distribution and metabolic status.
Topics: Abdomen; Adipose Tissue; Blood Glucose; Body Constitution; Dehydroepiandrosterone; Dehydroepiandrost | 2000 |
Exercise training-induced triglyceride lowering negatively correlates with DHEA levels in men with type 2 diabetes.
Topics: Adipose Tissue; Body Composition; Body Mass Index; Case-Control Studies; Dehydroepiandrosterone; Dia | 2001 |
Decreased steroidogenic enzyme 17,20-lyase and increased 17-hydroxylase activities in type 2 diabetes mellitus.
Topics: Adrenal Glands; Adult; Blood Glucose; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabet | 2002 |
42 other studies available for dehydroepiandrosterone and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Berberine Improves the Symptoms of DHEA-Induced PCOS Rats by Regulating Gut Microbiotas and Metabolites.
Topics: Animals; Berberine; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Female; Gastrointestinal Micr | 2021 |
Correlation of dehydroepiandrosterone with diabetic nephropathy and its clinical value in early detection.
Topics: Albumins; Albuminuria; Biomarkers; Cholesterol; Creatinine; Dehydroepiandrosterone; Diabetes Mellitu | 2022 |
Low Serum Dehydroepiandrosterone Is Associated With Diabetic Kidney Disease in Men With Type 2 Diabetes Mellitus.
Topics: Cross-Sectional Studies; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Diabetic Nephropathies; | 2022 |
[Features of steroidogenesis in men with hypogonadism and type 2 diabetes].
Topics: 17-alpha-Hydroxyprogesterone; Androgens; Cross-Sectional Studies; Dehydroepiandrosterone; Diabetes M | 2022 |
The impact of diabetes mellitus type 2 on the steroidogenesis of male Zucker Diabetic Fatty rats.
Topics: Animals; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Estradiol; Follicle Stimulating Hormone; | 2022 |
Low serum dehydroepiandrosterone levels are associated with diabetic retinopathy in patients with type 2 diabetes mellitus.
Topics: Cross-Sectional Studies; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Hu | 2023 |
Synthesis of menarandroside A from dehydroepiandrosterone.
Topics: Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Glucagon-Like Peptide 1; Humans; Oxidation-Reduct | 2023 |
AGER1 downregulation associates with fibrosis in nonalcoholic steatohepatitis and type 2 diabetes.
Topics: Animals; Ascorbic Acid; Cholecalciferol; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Disease | 2020 |
ATP synthase β-subunit abnormality in pancreas islets of rats with polycystic ovary syndrome and type 2 diabetes mellitus.
Topics: Adenosine Triphosphate; Animals; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Diet, High-Fat; | 2017 |
The possible role of stress induced hormonal disbalance in the patophysiology of insulin resistane in lean individuals.
Topics: Adiposity; alpha 1-Antitrypsin; Blood Glucose; Body Weight; Cardiovascular Diseases; Dehydroepiandro | 2018 |
Novel associations between sex hormones and diabetic vascular complications in men and postmenopausal women: a cross-sectional study.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; China; Cross-Sectional Studies; Dehydroepiandroste | 2019 |
The effect of metformin on androgen production in diabetic women with non-classic congenital adrenal hyperplasia.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adult; Androgens; Blood Glucose; Dehy | 2014 |
[Hormonal deficiencies in the elderly: is there a role for replacement therapy?].
Topics: Adjuvants, Immunologic; Aged; Aging; Androgens; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; F | 2014 |
Effect of dehydroepiandrosterone (DHEA) on Akt and protein kinase C zeta (PKCζ) phosphorylation in different tissues of C57BL6, insulin receptor substrate (IRS)1(-/-), and IRS2(-/-) male mice fed a high-fat diet.
Topics: Androstenedione; Animals; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Diet, High-Fat; Insulin | 2016 |
Serum dehydroepiandrosterone levels are associated with lower risk of type 2 diabetes: the Rotterdam Study.
Topics: Aged; Androstenedione; Cohort Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabe | 2017 |
Dioscorea esculenta-induced increase in muscle sex steroid hormones is associated with enhanced insulin sensitivity in a type 2 diabetes rat model.
Topics: Animals; Dehydroepiandrosterone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dioscor | 2017 |
Simultaneous determination of cell aging and ATP release from erythrocytes and its implications in type 2 diabetes.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Er | 2008 |
Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver.
Topics: 6-Aminonicotinamide; Animals; Cell Extracts; Cells, Cultured; Dehydroepiandrosterone; Diabetes Melli | 2009 |
The association of endogenous sex hormones, adiposity, and insulin resistance with incident diabetes in postmenopausal women.
Topics: Adipose Tissue; Adiposity; Aged; Aged, 80 and over; Blood Glucose; Cohort Studies; Dehydroepiandrost | 2009 |
Relationship between type 2 diabetes mellitus and hypothalamic-pituitary-adrenal axis.
Topics: Adult; Aged; Aged, 80 and over; Cushing Syndrome; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; | 2011 |
Effects of an 8-week aerobic exercise training on saliva steroid hormones, physical capacity, and quality of life in diabetic obese men.
Topics: Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Exercise; Humans; Hydrocortisone; Male; Middle Ag | 2012 |
Correlation of circulating dehydroepiandrosterone with activated protein C generation and carotid intima-media thickness in male patients with type 2 diabetes.
Topics: Adult; Aged; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Carotid Intima-Media Thickness | 2012 |
Molecular targets for 17α-ethynyl-5-androstene-3β,7β,17β-triol, an anti-inflammatory agent derived from the human metabolome.
Topics: Adipocytes; Androstenols; Animals; Anti-Inflammatory Agents; Autoimmunity; Cell Line; Dehydroepiandr | 2012 |
Dehydroepiandrosterone prevents the aggregation of platelets obtained from postmenopausal women with type 2 diabetes mellitus through the activation of the PKC/eNOS/NO pathway.
Topics: Blood Platelets; Cyclic GMP; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Enzyme Activation; E | 2012 |
Dehydroepiandrosterone in the type 1 diabetes mellitus.
Topics: Adolescent; Adult; Age Factors; Aging; Blood Glucose; Dehydroepiandrosterone; Dehydroepiandrosterone | 2012 |
Serum concentrations of delta 5-3 beta-hydroxysteroids in type 2 diabetes mellitus.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenediol; Dehydroepiandrosterone; Diabetes Mellitus, Type | 2002 |
An altered oxidant defense system in red blood cells affects their ability to release nitric oxide-stimulating ATP.
Topics: Adenosine Triphosphate; Animals; Case-Control Studies; Cattle; Cell Size; Dehydroepiandrosterone; Di | 2006 |
Elevated serum levels of interleukin-18 are associated with insulin resistance in women with polycystic ovary syndrome.
Topics: Blood Glucose; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Dehydroepiandrosterone; Diabetes | 2006 |
Enhanced adrenocortical activity as a contributing factor to diabetes in hyperandrogenic women.
Topics: Adrenal Cortex; Adult; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Female; Glucose Tolerance | 1994 |
Case report: amelioration of insulin resistance in diabetes with dehydroepiandrosterone.
Topics: Adolescent; Blood Glucose; Dehydroepiandrosterone; Dexamethasone; Diabetes Mellitus, Type 2; Drug Th | 1993 |
Drugs that suppress hepatic fat synthesis in starved-refed BHE/cdb rats also have an effect on muscle protein synthesis.
Topics: 2-Hydroxyphenethylamine; Adipose Tissue; Animals; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; | 1993 |
Relation of adrenal androgen to insulin levels.
Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes Mellitus, Type 2; Female; Humans; I | 1993 |
Dehydroepiandrosterone, dehydroepiandrosterone sulfate, obesity, waist-hip ratio, and noninsulin-dependent diabetes in postmenopausal women: the Rancho Bernardo Study.
Topics: Aged; Aged, 80 and over; Blood Glucose; Cross-Sectional Studies; Dehydroepiandrosterone; Dehydroepia | 1996 |
Depression of dehydroepiandrosterone in Japanese diabetic men--comparison between non-insulin-dependent diabetes mellitus and impaired glucose tolerance.
Topics: Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Glucose Intolerance; Glycated Hemoglobin; Humans; | 1996 |
Insulin sensitivity and sex steroid hormone levels during the menstrual cycle in healthy women with non-insulin-dependent diabetic parents.
Topics: Adult; Blood Glucose; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Estradiol; Female; Follicul | 1998 |
Reduced serum dehydroepiandrosterone levels in diabetic patients with hyperinsulinaemia.
Topics: Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes | 1998 |
GG-genotype in the promotor region of uncoupling-protein-1 gene is associated with lower level of dehydroepiandrosterone in type 2 diabetes.
Topics: Aged; Alleles; Blood Pressure; Carrier Proteins; Cholesterol; Dehydroepiandrosterone; Diabetes Melli | 2001 |
DHEA-PC slows the progression of type 2 diabetes (non-insulin-dependent diabetes mellitus) in the ZDF/Gmi-fa/fa rat.
Topics: Animals; Blood Glucose; Dehydroepiandrosterone; Diabetes Mellitus; Diabetes Mellitus, Type 2; Drug C | 2001 |
Dehydroepiandrosterone alters phospholipid profiles in Zucker rat muscle tissue.
Topics: Animals; Arachidonic Acid; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Fatty Acids; Heart; In | 2001 |
Lower endogenous androgen levels and dyslipidemia in men with non-insulin-dependent diabetes mellitus.
Topics: Aged; Aged, 80 and over; Androgens; Case-Control Studies; Cholesterol, HDL; Dehydroepiandrosterone; | 1992 |
Population study on the adipose tissue distribution in Japanese women born in 1948.
Topics: Adipose Tissue; Adult; Androstenedione; Body Composition; Coronary Disease; Dehydroepiandrosterone; | 1990 |
Peculiarities of the endocrine time structure in noninsulin-dependent adult-onset (type II) diabetes mellitus.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aged; Catecholamines; Cations; Circadian Rhyth | 1987 |