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dehydroepiandrosterone and Delayed Hypersensitivity

dehydroepiandrosterone has been researched along with Delayed Hypersensitivity in 9 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
"Dehydroepiandrosterone (DHEA) treatment provides diverse anti-inflammatory benefits in rodent models of diseases, including rheumatoid arthritis (RA), but only limited benefits to patients."7.75An orally bioavailable synthetic analog of an active dehydroepiandrosterone metabolite reduces established disease in rodent models of rheumatoid arthritis. ( Auci, DL; Boyle, DL; Firestein, GS; Frincke, JM; Garsd, A; Offner, H; Pieters, R; Reading, CL; White, SK, 2009)
"Dehydroepiandrosterone (DHEA) treatment provides diverse anti-inflammatory benefits in rodent models of diseases, including rheumatoid arthritis (RA), but only limited benefits to patients."3.75An orally bioavailable synthetic analog of an active dehydroepiandrosterone metabolite reduces established disease in rodent models of rheumatoid arthritis. ( Auci, DL; Boyle, DL; Firestein, GS; Frincke, JM; Garsd, A; Offner, H; Pieters, R; Reading, CL; White, SK, 2009)
"Dehydroepiandrosterone (DHEA) exerts a variety of positive effects on the immunologic alterations after trauma and sepsis."3.71Dehydroepiandrosterone (DHEA) modulates the activity and the expression of lymphocyte subpopulations induced by cecal ligation and puncture. ( Böttcher, F; Breddin, M; Dahlweid, FM; Giannoudis, PV; Pape, HC; van Griensven, M; Wittwer, T, 2002)
"Sepsis is associated with depression of T cell-dependent immune reactivity with proinflammatory cytokines, such as tumour necrosis factor (TNF)-alpha, playing an important role."1.32Are alterations of lymphocyte subpopulations in polymicrobial sepsis and DHEA treatment mediated by the tumour necrosis factor (TNF)-alpha receptor (TNF-RI)? A study in TNF-RI (TNF-RI(-/-)) knock-out rodents. ( Harwood, P; Hildebrand, F; Krettek, C; Pape, HC; van Griensven, M; Wittwer, T, 2004)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's3 (33.33)18.2507
2000's4 (44.44)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rearte, B1
Maglioco, A1
Machuca, D1
Greco, DM1
Landoni, VI1
Rodriguez-Rodrigues, N1
Meiss, R1
Fernández, GC1
Isturiz, MA1
Offner, H1
Firestein, GS1
Boyle, DL1
Pieters, R1
Frincke, JM1
Garsd, A1
White, SK1
Reading, CL1
Auci, DL1
van Griensven, M2
Dahlweid, FM1
Giannoudis, PV1
Wittwer, T2
Böttcher, F1
Breddin, M1
Pape, HC2
Röntzsch, A1
Thoss, K1
Petrow, PK1
Henzgen, S1
Bräuer, R1
Hildebrand, F1
Harwood, P1
Krettek, C1
Kim, HR1
Ryu, SY1
Kim, HS1
Choi, BM1
Lee, EJ1
Kim, HM1
Chung, HT1
Bernton, E1
Hoover, D1
Galloway, R1
Popp, K1
Wolvers, DA1
Bakker, JM1
Bagchus, WM1
Kraal, G1
Mackay, WD1
Bulbrook, RD1
Wang, DY1
Edwards, MH1

Other Studies

9 other studies available for dehydroepiandrosterone and Delayed Hypersensitivity

ArticleYear
Dehydroepiandrosterone and metyrapone partially restore the adaptive humoral and cellular immune response in endotoxin immunosuppressed mice.
    Innate immunity, 2014, Volume: 20, Issue:6

    Topics: Adaptive Immunity; Animals; CD4 Lymphocyte Count; Cell Proliferation; Dehydroepiandrosterone; Glucoc

2014
An orally bioavailable synthetic analog of an active dehydroepiandrosterone metabolite reduces established disease in rodent models of rheumatoid arthritis.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antibodies; Antibody Formation; Arthritis, Rheumatoid; Collagen;

2009
Dehydroepiandrosterone (DHEA) modulates the activity and the expression of lymphocyte subpopulations induced by cecal ligation and puncture.
    Shock (Augusta, Ga.), 2002, Volume: 18, Issue:5

    Topics: Adjuvants, Immunologic; Animals; CD8-Positive T-Lymphocytes; Dehydroepiandrosterone; Disease Models,

2002
Amelioration of murine antigen-induced arthritis by dehydroepiandrosterone (DHEA).
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53, Issue:5

    Topics: Adjuvants, Immunologic; Androstenediol; Animals; Antibodies, Anti-Idiotypic; Arthritis, Experimental

2004
Are alterations of lymphocyte subpopulations in polymicrobial sepsis and DHEA treatment mediated by the tumour necrosis factor (TNF)-alpha receptor (TNF-RI)? A study in TNF-RI (TNF-RI(-/-)) knock-out rodents.
    Clinical and experimental immunology, 2004, Volume: 138, Issue:2

    Topics: Animals; Body Temperature; Body Weight; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Dehy

2004
Administration of dehydroepiandrosterone reverses the immune suppression induced by high dose antigen in mice.
    Immunological investigations, 1995, Volume: 24, Issue:4

    Topics: Animals; Antigens; Cells, Cultured; Dehydroepiandrosterone; Dose-Response Relationship, Immunologic;

1995
Adaptation to chronic stress in military trainees. Adrenal androgens, testosterone, glucocorticoids, IGF-1, and immune function.
    Annals of the New York Academy of Sciences, 1995, Dec-29, Volume: 774

    Topics: Adaptation, Physiological; Adrenal Glands; Adult; Body Composition; Chronic Disease; Dehydroepiandro

1995
The steroid hormone dehydroepiandrosterone (DHEA) breaks intranasally induced tolerance, when administered at time of systemic immunization.
    Journal of neuroimmunology, 1998, Aug-14, Volume: 89, Issue:1-2

    Topics: Administration, Intranasal; Androstenediols; Androstenols; Animals; Antibodies; Antibody Formation;

1998
Relation between plasma-cortisol, plasma-androgen-sulphates, and immune response in women with breast cancer.
    Lancet (London, England), 1971, Volume: 2, Issue:7732

    Topics: Adult; Aged; Androgens; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Hydr

1971