Page last updated: 2024-11-07

dehydroepiandrosterone and Cushing Syndrome

dehydroepiandrosterone has been researched along with Cushing Syndrome in 96 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Cushing Syndrome: A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.

Research Excerpts

ExcerptRelevanceReference
"The therapeutic value of ketoconazole for long term treatment of patients with Cushing's syndrome was studied."7.67Use of ketoconazole in the treatment of Cushing's syndrome. ( Berselli, ME; Loli, P; Tagliaferri, M, 1986)
"Seven patients with Cushing's syndrome were treated with trilostane (WIN 24,540) 4 alpha,5-epoxy-17 beta-hydroxy-3-oxo-5 alpha-androstane-2 alpha-carbonitrile), an inhibitor of adrenal steroid biosynthesis."7.66Treatment of Cushing's syndrome with trilostane (WIN 24,540), an inhibitor of adrenal steroid biosynthesis. ( Komanicky, P; Melby, JC; Spark, RF, 1978)
"Cortisol production by hepatocellular carcinoma (HCC) has not been previously reported and dehydroepiandrosterone (DHEA) secretion by HCC is rare."3.81Possible ACTH-independent, cortisol-secreting and DHEA-secreting metastatic hepatocellular carcinoma causing Cushing's syndrome. ( Bahtiyar, G; Inoue, T; Sacerdote, A; Thomas, N, 2015)
"Reduced serum levels of dehydroepiandrosterone sulphate (DHEAS) have been shown in patients with Cushing's syndrome resulting from adrenocortical adenoma, in contrast with normal DHEAS levels in patients with Cushing's disease."3.69Reduced serum levels of dehydroepiandrosterone sulphate in adrenal incidentalomas: a marker of adrenocortical tumour. ( Blatto, A; Camanni, F; Carlini, M; Flecchia, D; Mazza, E; Messina, M; Olivieri, F; Serra, G, 1995)
" We have compared plasma cortisol values with plasma levels of androstenedione, dehydroepiandrosterone (DHEA), DHEA-sulphate (DHEAS), testosterone and an index of free testosterone, the testosterone/sex hormone binding globulin ratio, prior to treatment in patients with Cushing's syndrome."3.69Dissociation of adrenal androgen and cortisol secretion in Cushing's syndrome. ( Cunningham, SK; McKenna, TJ, 1994)
"All the women with adrenal tumors had elevated basal serum concentrations of testosterone or dehydroepiandrosterone sulfate, as compared with 36 of the 73 women with non-neoplastic hirsutism (sensitivity, 100 percent; 95 percent confidence interval, 77 to 100; specificity, 50 percent; 95 percent confidence interval, 38 to 62)."3.69Identification of virilizing adrenal tumors in hirsute women. ( Derksen, J; Haak, HR; Meinders, AE; Nagesser, SK; van de Velde, CJ, 1994)
"We studied the contents of cortisol (F) and dehydroepiandrosterone (DHEA) and the expression of mRNA of cytochrome P-450 for side-chain cleavage (P-450scc), 17 alpha-hydroxylase (P-450c17), 21 alpha-hydroxylase (P-450c21) and 11 beta-hydroxylase (P-450c11) in adrenocortical adenomas from three patients with Cushing's syndrome."3.68Markedly increased expression of cytochrome P-450 17 alpha-hydroxylase (P-450c17) mRNA in adrenocortical adenomas from patients with Cushing's syndrome. ( Haji, M; Nawata, H; Ogo, A; Ohashi, M, 1991)
"Previous reports on patients with endogenous Cushing's syndrome describe low concentrations of the adrenal androgen dehydroepiandrosterone sulfate (DHEA-S) in adrenal adenoma and in a case of feminizing macronodular hyperplasia."3.67Decreased dehydroepiandrosterone sulfate in pigmented nodular adrenal dysplasia. ( Braithwaite, SS; Collins, S; Prinz, RA; Walloch, JL; Winters, GL, 1989)
"We investigated the mechanism of dissociation of cortisol and dehydroepiandrosterone sulfate (DHEA-S) secretion by the adrenal glands after the removal of an adrenal gland containing an adrenocortical adenoma in a patient with Cushing's syndrome."3.67Mechanism of dissociation of cortisol and adrenal androgen secretion after removal of adrenocortical adenoma in patients with Cushing's syndrome. ( Higuchi, K; Ibayashi, H; Kato, K; Nawata, H; Takayanagi, R; Yanase, T, 1985)
"The therapeutic value of ketoconazole for long term treatment of patients with Cushing's syndrome was studied."3.67Use of ketoconazole in the treatment of Cushing's syndrome. ( Berselli, ME; Loli, P; Tagliaferri, M, 1986)
" Based on their experience, the authors suggest an inexpensive investigative strategy in hyperandrogenic females consisting of the following: the first step depends upon the clinical symptoms--in cases of hirsutism with regular menstrual cycles, plasma testosterone (T) and plasma dehydroepiandrosterone sulfate (DHA-S) are assayed, and the basal body temperature chart is recorded."3.66Investigative strategy of hyperandrogenism in women. ( Buvat, J; Buvat-Herbaut, M; Dewailly, D; Fossati, P; Marcolin, G; Racadot, A, 1983)
"Seven patients with Cushing's syndrome were treated with trilostane (WIN 24,540) 4 alpha,5-epoxy-17 beta-hydroxy-3-oxo-5 alpha-androstane-2 alpha-carbonitrile), an inhibitor of adrenal steroid biosynthesis."3.66Treatment of Cushing's syndrome with trilostane (WIN 24,540), an inhibitor of adrenal steroid biosynthesis. ( Komanicky, P; Melby, JC; Spark, RF, 1978)
"Many dysfunctional and chronic pain conditions overlap."2.53Dysfunctional stress responses in chronic pain. ( Dutheil, F; Picard, P; Woda, A, 2016)
"Hirsutism is a common medical condition that in most women is due to the polycystic ovary syndrome or is idiopathic."2.39Approach to patients with hirsutism. ( Sakiyama, R, 1996)
"Clinical virilization with or without hypercortisolism was found in all eight children, who were 5 years old or younger."2.37Virilizing adrenocortical tumors in childhood: eight cases and a review of the literature. ( Green, OC; Lee, PD; Winter, RJ, 1985)
"Cushing's syndrome was diagnosed in a 14 year old girl and, 5 years later, in her nephew (sister's son) also when he was 14 years of age."1.27Familial Cushing's syndrome due to pigmented multinodular adrenocortical dysplasia. ( Böhm, N; Lippmann-Grob, B; von Petrykowski, W, 1983)
"The carcinomas have a block in the conversion of 11-deoxycortisol to cortisol with a subsequent accumulation in androgen and cortisol precursors."1.27Steroid content of the peripheral and adrenal vein in Cushing's syndrome due to adrenocortical adenoma and carcinoma. ( Gabrilove, JL; Levine, AC; Mitty, HA, 1988)
"Seven ovarian tumors were localized."1.26[Diagnosis in progressive hirsutism. Catheter technique and results (author's transl)]. ( Moltz, L; Sörensen, R, 1981)
"Virilism is the major manifestation in children (83 percent of the cases), either isolated or associated with hypercortisolism and/or feminization."1.25[Corticosuprarenaloma in children]. ( Benaily, M; Job, JC; Schweisguth, O, 1975)

Research

Studies (96)

TimeframeStudies, this research(%)All Research%
pre-199060 (62.50)18.7374
1990's20 (20.83)18.2507
2000's8 (8.33)29.6817
2010's7 (7.29)24.3611
2020's1 (1.04)2.80

Authors

AuthorsStudies
Gao, C1
Ding, L1
Zhang, X1
Yuan, M1
Tang, S1
Li, W1
Ye, Y1
Liu, M1
He, Q1
El Asmar, N1
Rajpal, A1
Selman, WR1
Arafah, BM1
Monno, S1
Tachikawa, T1
Maekawa, T1
Sasano, H3
Sacerdote, A1
Inoue, T1
Thomas, N1
Bahtiyar, G1
Woda, A1
Picard, P1
Dutheil, F1
Velikanova, LI1
Shafigullina, ZR1
Lisitsin, AA1
Vorokhobina, NV1
Grigoryan, K1
Kukhianidze, EA1
Strelnikova, EG1
Krivokhizhina, NS1
Krasnov, LM1
Fedorov, EA1
Sablin, IV1
Moskvin, AL1
Bessonova, EA1
Kerlik, J1
Penesova, A1
Vlcek, M1
Imrich, R1
Starka, L2
Radikova, Z1
Ashida, K1
Akehi, Y1
Kudo, T1
Yanase, T2
Felšöci, M1
Schroner, Z1
Petrovičová, J1
Lazúrová, I1
Wolkowitz, OM1
Epel, ES1
Reus, VI1
NATOLI, A1
MAGLIOCCA, R1
KOMOR, K1
TRETBAR, HA1
CAWLEY, LP1
GOLDZIEHER, JW1
POCHI, PE1
STRAUSS, JS1
MESCON, H1
LAMB, EJ2
DIGNAM, WJ2
PION, RJ2
SIMMER, HH2
CALVIN, HI1
LIEBERMAN, S1
VILLEE, DB1
CONRAD, SH1
LINDBERG, MC1
HERRMANN, WL1
IACONO, G1
BRANCACCIO, A1
D ALESSANDRO, B1
DELUCA, R1
REPOLE, R1
Dhatariya, K1
Goto, K1
Nawata, H4
Fukai, N1
Hirono, Y1
Yoshimoto, T1
Doi, M1
Ohtsuka, Y1
Homma, K1
Shibata, H1
Hirata, Y1
Gallagher, P1
Watson, S1
Smith, MS1
Young, AH1
Ferrier, IN1
Hauffa, BP1
Kaplan, SL1
Grumbach, MM1
Ashcraft, MW1
Van Herle, AJ1
Vener, SL1
Geffner, DL1
Sörensen, R1
Moltz, L1
Ferramosca, B1
Bertoni, F1
Serra, D1
Ravaglia, G1
Böhm, N1
Lippmann-Grob, B1
von Petrykowski, W1
Buvat, J1
Dewailly, D1
Marcolin, G1
Buvat-Herbaut, M1
Racadot, A1
Fossati, P1
Morosini, PP1
Campanella, N1
Butini, L1
Maniscalco, L1
Sabbatini, A1
Marcolini, P1
Yamaji, T2
Ishibashi, M1
Sekihara, H2
Itabashi, A1
Yanaihara, T1
Watanobe, H2
Kannari, K2
Murabayashi, S1
Kimura, K2
Takebe, K2
Ojima, M1
Suzuki, K1
Schteingart, DE1
Tsao, HS1
Taylor, CI1
McKenzie, A1
Victoria, R1
Therrien, BA1
Friess, E1
Wiedemann, K1
Steiger, A1
Holsboer, F1
Watson, RE1
Bouknight, R1
Alguire, PC1
Murakami, Y1
Sasaki, M1
Suzuki, T1
Kitamura, N1
Tomoi, M1
Yorifuji, H1
Koshimura, K1
Kato, Y1
Flecchia, D1
Mazza, E1
Carlini, M1
Blatto, A1
Olivieri, F1
Serra, G1
Camanni, F1
Messina, M1
Cunningham, SK2
McKenna, TJ3
Derksen, J1
Nagesser, SK1
Meinders, AE1
Haak, HR1
van de Velde, CJ1
Kitahara, M1
Mori, T1
Seki, H1
Washizawa, K1
Amano, Y1
Nakahata, T1
Takeuchi, S1
Inaba, H1
Hotchi, M1
Komiyama, A1
Lucon, AM1
Mendonça, BB1
Domenice, S1
Chambô, JL1
Wajchemberg, BL1
Arap, S1
Bunch, FT1
Warner, BA1
Hanson, JA1
Weber, A1
Reznek, RH1
Cotterill, AM1
Ross, RJ1
Harris, RJ1
Armstrong, P1
Savage, MO1
Sakiyama, R1
Sandrini, R1
Ribeiro, RC1
DeLacerda, L1
Boronat, M1
Moreno, A1
Ramón y Cajal, S1
Pineda, E1
Lucas, T1
Estrada, J1
Hechter, O1
Grossman, A1
Chatterton, RT1
Kołomecki, K1
Stepień, H1
Narebski, JM1
Tsagarakis, S1
Tsigos, C1
Vassiliou, V1
Tsiotra, P1
Pratsinis, H1
Kletsas, D1
Trivizas, P1
Nikou, A1
Mavromatis, T1
Sotsiou, F1
Raptis, S1
Thalassinos, N1
Hayashida, K1
Inui, A1
Kinugasa, A1
Tomizawa, M1
Sawada, J1
Cattaneo, S1
Forti, G1
Fiorelli, G1
Barbieri, U1
Serio, M1
Benaily, M1
Schweisguth, O1
Job, JC1
Sennett, JA1
Liddle, GW1
Yarbro, LR1
Metcalf, MG2
Komanicky, P1
Spark, RF1
Melby, JC3
Blevins, LS1
Hall, GS1
Madoff, DH1
Laws, ER1
Wand, GS1
Nestler, JE1
McClanahan, MA1
Kleiber, H1
Rey, F1
Temler, E1
Gomez, F1
Louard, RJ1
Gelfand, RA1
Ogo, A2
Haji, M1
Ohashi, M1
Littley, MD1
Pollock, A1
Kane, J1
Shalet, SM1
Jackson, JA1
Fachnie, JD1
Mellinger, RC1
Braithwaite, SS1
Collins, S1
Prinz, RA1
Walloch, JL1
Winters, GL1
Higuchi, K1
Takayanagi, R1
Kato, K1
Ibayashi, H2
Levine, AC1
Mitty, HA1
Gabrilove, JL2
Loughlin, T1
Loli, P1
Berselli, ME1
Tagliaferri, M1
Lee, PD1
Winter, RJ1
Green, OC1
Rivera, R1
Dorfman, RI1
Forchielli, E1
Wieland, RG1
Vorys, N1
Folk, RL1
Hamwi, GJ1
Detter, F1
Kollmeier, W1
Klingmüller, V1
Horký, K1
Küchel, O1
Gregorvá, I1
Mahesh, VB1
Pria, SD1
Greenblatt, RB1
Neville, AM1
Orr, JC1
Trofimow, ND1
Engel, LL1
Tamaoki, BI1
Vaitukaitis, JL1
Göbel, P2
Cyran, J1
Gordon, ES1
Sarada, T1
Garmendia, F1
Nicolis, GL1
Crook, D1
Blunck, W1
Mizutani, S1
Sonoda, T1
Seki, T1
Matsumoto, K1
Staub, JJ1
Philbert, M1
Luton, JP1
Bricaire, H1
Takahara, J1
Hashimoto, K1
Ofuji, T1
Morimoto, Y1
Hiwada, K1
Nanahoshi, M1
Yano, S1
Kumagai, A1
Yamamura, Y1
Koto, K1
Uda, H1
Okano, K1
Yamane, G1
Takeda, R1
Noto, Y1
Korth-Schutz, S1
Levine, LS1
Merkatz, IR1
New, MI1

Reviews

15 reviews available for dehydroepiandrosterone and Cushing Syndrome

ArticleYear
Dysfunctional stress responses in chronic pain.
    Psychoneuroendocrinology, 2016, Volume: 71

    Topics: Chronic Pain; Cushing Syndrome; Cytokines; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; H

2016
Stress hormone-related psychopathology: pathophysiological and treatment implications.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2001, Volume: 2, Issue:3

    Topics: Antidepressive Agents; Cognition Disorders; Corticosterone; Cushing Syndrome; Dehydroepiandrosterone

2001
[DHEA, DHEA-S].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 8

    Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Biomarkers; Cushing

2005
The hypothalamic-pituitary-adrenocortical system and sleep in man.
    Advances in neuroimmunology, 1995, Volume: 5, Issue:2

    Topics: Adrenocorticotropic Hormone; Amino Acid Sequence; Animals; Circadian Rhythm; Corticotropin-Releasing

1995
Hirsutism: evaluation and management.
    Journal of general internal medicine, 1995, Volume: 10, Issue:5

    Topics: Cushing Syndrome; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diagnosis, Differential; F

1995
Cushing's disease with a unilateral adrenal macronodule: evolutive transition or incidental finding?
    Southern medical journal, 1993, Volume: 86, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adult; Comorbidity; Cushing Syndrome; D

1993
Approach to patients with hirsutism.
    The Western journal of medicine, 1996, Volume: 165, Issue:6

    Topics: 17-alpha-Hydroxyprogesterone; Cushing Syndrome; Dehydroepiandrosterone; Female; Hirsutism; Humans; H

1996
Diabetes and adrenal disease.
    Bailliere's clinical endocrinology and metabolism, 1992, Volume: 6, Issue:4

    Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Animals; Cushing Syndrome; Dehydroepiandrosterone;

1992
The adrenal cortex and virilization.
    Clinics in endocrinology and metabolism, 1985, Volume: 14, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyper

1985
Virilizing adrenocortical tumors in childhood: eight cases and a review of the literature.
    Pediatrics, 1985, Volume: 76, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adenoma; Adrenal Cortex Neoplasms; Child

1985
Metabolic aspects of obesity.
    Advances in metabolic disorders, 1970, Volume: 4

    Topics: Acidosis; Adenosine Triphosphate; Adipose Tissue; Adrenal Cortex Hormones; Alcoholism; Animals; Body

1970
Assessment of adrenocortical function.
    The New England journal of medicine, 1971, Sep-23, Volume: 285, Issue:13

    Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenal Glands; Adrenal Insufficiency; Adult; Aldoster

1971
[Some diagnostic and therapeutic aspects of adrenal disorders in childhood (author's transl)].
    Monatsschrift fur Kinderheilkunde, 1973, Volume: 121, Issue:10

    Topics: Addison Disease; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; A

1973
[Clinical findings and laboratory diagnosis in Cushing's syndrome].
    Praxis, 1968, Oct-15, Volume: 57, Issue:41

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic

1968
[Adrenocortical hormones and arteriosclerosis].
    Horumon to rinsho. Clinical endocrinology, 1972, Volume: 20, Issue:8

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Androgens; Arteriosclerosis

1972

Trials

2 trials available for dehydroepiandrosterone and Cushing Syndrome

ArticleYear
Qualitative alterations in urinary 17-ketosteroid excretion during aminoglutethimide administration.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:2

    Topics: 17-Ketosteroids; Adrenocortical Hyperfunction; Aminoglutethimide; Androsterone; Aniline Compounds; A

1969
Plasma dehydroepiandrosterone sulfate in normal and pathological conditions.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:2

    Topics: Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction;

1969

Other Studies

79 other studies available for dehydroepiandrosterone and Cushing Syndrome

ArticleYear
Distinct serum steroid profiles between adrenal Cushing syndrome and Cushing disease.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Adrenocorticotropic Hormone; Chromatography, Liquid; Cushing Syndrome; Dehydroepiandrosterone; Dehyd

2023
The Value of Perioperative Levels of ACTH, DHEA, and DHEA-S and Tumor Size in Predicting Recurrence of Cushing Disease.
    The Journal of clinical endocrinology and metabolism, 2018, 02-01, Volume: 103, Issue:2

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Deh

2018
A case of Cushing's syndrome due to bilateral cortisol-secreting adenomas with unilateral DHEAS oversecretion.
    Endocrine journal, 2015, Volume: 62, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Cushing Syndrome; Dehydroepi

2015
Possible ACTH-independent, cortisol-secreting and DHEA-secreting metastatic hepatocellular carcinoma causing Cushing's syndrome.
    BMJ case reports, 2015, Dec-23, Volume: 2015

    Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Biopsy

2015
Different Types of Urinary Steroid Profiling Obtained by High-Performance Liquid Chromatography and Gas Chromatography-Mass Spectrometry in Patients with Adrenocortical Carcinoma.
    Hormones & cancer, 2016, Volume: 7, Issue:5-6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adrenocortical Carcinoma; Adult; Chromatography, H

2016
Effects of endogenous and exogenous hypercortisolemia on low-dose adrenocorticotropin test outcome in humans.
    Journal of endocrinological investigation, 2009, Volume: 32, Issue:8

    Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Adult; Androstenedione; Cushing Syndrome;

2009
[DHEA, DHEA-S].
    Nihon rinsho. Japanese journal of clinical medicine, 2010, Volume: 68 Suppl 7

    Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Cushing Syndrome; Dehydroepiandrosterone;

2010
Relationship between type 2 diabetes mellitus and hypothalamic-pituitary-adrenal axis.
    Wiener klinische Wochenschrift, 2011, Volume: 123, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Cushing Syndrome; Dehydroepiandrosterone; Diabetes Mellitus, Type 2;

2011
[Urinary elimination of 17-ketosteroids and dehydroisoandrosterone in patients with various endocrine diseases (Addison's disease, Cushing's disease, Cushing's syndrome, precocious puberty caused by congenital adrenal hyperplasia, acromegaly)].
    Il Progresso medico, 1955, Jun-30, Volume: 11, Issue:12

    Topics: 17-Ketosteroids; Acromegaly; Addison Disease; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperf

1955
[ON THE TREATMENT OF ADRENAL CORTEX DISEASES].
    Magyar belorvosi archivum (1955), 1963, Volume: 16

    Topics: Addison Disease; Adrenal Cortex Diseases; Adrenal Insufficiency; Adrenocortical Hyperfunction; Adren

1963
CUSHING'S SYNDROME.
    The Journal of the Kansas Medical Society, 1963, Volume: 64

    Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Androgens; Androsterone; Carcinoma; Carcinoma, Broncho

1963
ORIGINS OF HIRSUTISM AND VIRILISM.
    Texas state journal of medicine, 1963, Volume: 59

    Topics: Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Cushing Syndrome; Dehydroepiandrosterone; D

1963
THE ROLE OF ADRENOCORTICAL STEROIDS IN THE CONTROL OF HUMAN SEBACEOUS GLAND ACTIVITY.
    The Journal of investigative dermatology, 1963, Volume: 41

    Topics: Addison Disease; Adrenal Cortex Hormones; Adrenal Insufficiency; Adrenalectomy; Androsterone; Cushin

1963
PLASMA ANDROGENS IN WOMEN. I. NORMAL AND NON-HIRSUTE FEMALES, OOPHORECTOMIZED AND ADRENALECTOMIZED PATIENTS.
    Acta endocrinologica, 1964, Volume: 45

    Topics: 17-Ketosteroids; Adolescent; Adrenalectomy; Androgens; Androsterone; Blood Chemical Analysis; Breast

1964
PLASMA ANDROGENS IN WOMEN. II. PATIENTS WITH POLYCYSTIC OVARIES AND HIRSUTISM.
    Acta endocrinologica, 1964, Volume: 45

    Topics: Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Androgens; Androsterone; Blood Chemical Ana

1964
EVIDENCE THAT STEROID SULFATES SERVE AS BIOSYNTHETIC INTERMEDIATES. II. IN VITRO CONVERSION OF PREGNENOLONE-3H SULFATE-35S TO 17ALPHA-HYDROXYPREGNENOLONE-3H SULFATE-35S.
    Biochemistry, 1964, Volume: 3

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography; Cushing Syndrome; Dehydroepiandrostero

1964
EFFECTS OF SUBSTRATES AND COFACTORS ON STEROID SYNTHESIS IN HYPERPLASTIC ADRENALS.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adrenal Hyperplasia, Congenital; Carbon Isotope

1964
SIGNIFICANCE OF PLASMA DEHYDROISOANDROSTERONE AND ANDROSTERONE SULFATES IN THE DIAGNOSIS OF VIRILIZING DISORDERS.
    American journal of obstetrics and gynecology, 1965, Feb-15, Volume: 91

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Amenorrhea; Androsterone; Blood C

1965
[STUDY OF ADRENAL CORTEX FUNCTION AFTER ADMINISTRATION OF HYDROCHLOROTHIAZIDE IN NORMAL SUBJECTS AND PATIENTS WITH ADRENAL GLAND DISEASES].
    Folia endocrinologica, 1964, Volume: 17

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adrenal Cortex; Adrenal Gland Diseases;

1964
DHEA levels in treated Cushing's disease may contribute to low quality of life.
    Clinical endocrinology, 2005, Volume: 62, Issue:2

    Topics: Cushing Syndrome; Dehydroepiandrosterone; Humans; Quality of Life

2005
A case of estrogen-secreting adrenocortical carcinoma with subclinical Cushing's syndrome.
    Endocrine journal, 2006, Volume: 53, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Cushing Syndrome; Dehydroepiandrosterone;

2006
Plasma cortisol-dehydroepiandrosterone (DHEA) ratios in schizophrenia and bipolar disorder.
    Schizophrenia research, 2007, Volume: 90, Issue:1-3

    Topics: Adult; Age Factors; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Biomarkers; Bipol

2007
Dissociation between plasma adrenal androgens and cortisol in Cushing's disease and ectopic ACTH-producing tumour: relation to adrenarche.
    Lancet (London, England), 1984, Jun-23, Volume: 1, Issue:8391

    Topics: ACTH Syndrome, Ectopic; Adenoma, Islet Cell; Adolescent; Adrenal Cortex; Adrenocorticotropic Hormone

1984
Serum cortisol levels in Cushing's syndrome after low- and high-dose dexamethasone suppression.
    Annals of internal medicine, 1982, Volume: 97, Issue:1

    Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Cushing Syndrome; Dehydroepiandrosterone; Dexamethason

1982
[Diagnosis in progressive hirsutism. Catheter technique and results (author's transl)].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1981, Volume: 135, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Catheterization; Cushing Syndrome; Dehydroepia

1981
[The male gonad in an adrenometabolic syndrome. Morpho-functional findings].
    Minerva medica, 1982, Nov-10, Volume: 73, Issue:43

    Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adult; Circadian Rhythm; Cushing Syndrome; Dehydroepiandr

1982
Familial Cushing's syndrome due to pigmented multinodular adrenocortical dysplasia.
    Acta endocrinologica, 1983, Volume: 102, Issue:3

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex; Adrenalectomy; Child; Cosyntropin; Cushing Syndrome; De

1983
Investigative strategy of hyperandrogenism in women.
    Hormone research, 1983, Volume: 18, Issue:1-3

    Topics: Adrenal Hyperplasia, Congenital; Androgens; Cushing Syndrome; Dehydroepiandrosterone; Female; Gonado

1983
[Blood amino acids pattern in Cushing's syndrome].
    Giornale di clinica medica, 1983, Volume: 64, Issue:12

    Topics: Adult; Amino Acids; Blood Glucose; Cushing Syndrome; Dehydroepiandrosterone; Dehydroepiandrosterone

1983
Serum dehydroepiandrosterone sulfate in Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 1984, Volume: 59, Issue:6

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Cushing Syndrome; Dehydroepiandrosterone; Dehyd

1984
[A case of adrenocortical carcinoma with Cushing's syndrome presenting unusual urinary 17-ketosteroid fractionation].
    Gan no rinsho. Japan journal of cancer clinics, 1984, Volume: 30, Issue:14

    Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Neoplasms; Adult; Androsterone; Cushing Syndrome; Dehydroe

1984
Sustained remission of Cushing's disease with mitotane and pituitary irradiation.
    Annals of internal medicine, 1980, Volume: 92, Issue:5

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Cobalt Radioisotopes; Cushing Syndrome; Dehydroepiandro

1980
Young female patient with testosterone-producing adrenocortical adenoma also showing signs of subclinical Cushing's syndrome.
    Endocrine journal, 1995, Volume: 42, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Cortex Neoplasms; Adult; Circadian Rhyt

1995
Reduced serum levels of dehydroepiandrosterone sulphate in adrenal incidentalomas: a marker of adrenocortical tumour.
    Clinical endocrinology, 1995, Volume: 42, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult;

1995
Dissociation of adrenal androgen and cortisol secretion in Cushing's syndrome.
    Clinical endocrinology, 1994, Volume: 41, Issue:6

    Topics: ACTH Syndrome, Ectopic; Adolescent; Adrenal Glands; Adult; Androgens; Androstenedione; Cushing Syndr

1994
Identification of virilizing adrenal tumors in hirsute women.
    The New England journal of medicine, 1994, Oct-13, Volume: 331, Issue:15

    Topics: 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Androstenedione; Carcinoma; Cu

1994
Malignant paraganglioma presenting as Cushing syndrome with virilism in childhood. Production of cortisol, androgens, and adrenocorticotrophic hormone by the tumor.
    Cancer, 1993, Dec-01, Volume: 72, Issue:11

    Topics: Adrenocorticotropic Hormone; Androgens; Catecholamines; Child; Cushing Syndrome; Dehydroepiandroster

1993
Adrenal autografts following bilateral adrenalectomy.
    The Journal of urology, 1993, Volume: 149, Issue:5

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Aldoster

1993
Magnetic resonance imaging of adrenocortical adenomas in childhood: correlation with computed tomography and ultrasound.
    Pediatric radiology, 1996, Volume: 26, Issue:11

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hor

1996
Childhood adrenocortical tumors.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:7

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Neoplasms; Age Factors; Child; Child, Preschool; Cushing

1997
Subclinical Cushing's syndrome due to adrenal myelolipoma.
    Archives of pathology & laboratory medicine, 1997, Volume: 121, Issue:7

    Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aged; Cushing Syndrome; Dehydroepiandrosterone

1997
Relationship of dehydroepiandrosterone and cortisol in disease.
    Medical hypotheses, 1997, Volume: 49, Issue:1

    Topics: Adrenal Cortex Hormones; Aging; Animals; Circadian Rhythm; Cushing Syndrome; Dehydroepiandrosterone;

1997
Vascular endothelial growth factor and basic fibroblast growth factor evaluation in blood serum of patients with hormonally active and inactive adrenal gland tumours.
    Cytobios, 2000, Volume: 101, Issue:396

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Medulla; Adrenalectomy; Adult; Aged; Carc

2000
Food-dependent androgen and cortisol secretion by a gastric inhibitory polypeptide-receptor expressive adrenocortical adenoma leading to hirsutism and subclinical Cushing's syndrome: in vivo and in vitro studies.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult;

2001
[Adrenal cortex adenoma with unilateral obesity--its endocrine function and diagnosis].
    Horumon to rinsho. Clinical endocrinology, 1975, Volume: 23, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Child, Preschool; Cushing Syndrome; Dehy

1975
A rapid radioimmunoassay for determination of dehydroepiandrosterone sulphate in human plasma.
    Clinical endocrinology, 1975, Volume: 4, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adult; Age Factors; Aged; Cushing Syndrome;

1975
[Corticosuprarenaloma in children].
    Archives francaises de pediatrie, 1975, Volume: 32, Issue:5

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal G

1975
Plasma 16 beta-hydroxydehydroepiandrosterone in normal and pathological conditions in man.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 43, Issue:5

    Topics: Adolescent; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Child; Ch

1976
Dehydroepiandrosterone--sulphate in urine.
    Clinical biochemistry, 1978, Volume: 11, Issue:2

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocorticotropic

1978
Treatment of Cushing's syndrome with trilostane (WIN 24,540), an inhibitor of adrenal steroid biosynthesis.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:5

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adu

1978
Case report: acromegaly and Cushing's disease in a patient with synchronous pituitary adenomas.
    The American journal of the medical sciences, 1992, Volume: 304, Issue:5

    Topics: 17-Ketosteroids; Acromegaly; Adenoma; Adult; Cushing Syndrome; Dehydroepiandrosterone; Dehydroepiand

1992
Dissociated recovery of cortisol and dehydroepiandrosterone sulphate after treatment for Cushing's syndrome.
    Journal of endocrinological investigation, 1991, Volume: 14, Issue:6

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Aged; Cushing Syndrome;

1991
Recurrent Cushing's disease with low adrenal androgen production.
    Journal of endocrinological investigation, 1991, Volume: 14, Issue:11

    Topics: 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androgens; Cushing Syndrome; De

1991
Markedly increased expression of cytochrome P-450 17 alpha-hydroxylase (P-450c17) mRNA in adrenocortical adenomas from patients with Cushing's syndrome.
    Molecular and cellular endocrinology, 1991, Volume: 80, Issue:1-3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Blotting, Northern; Cushing Syndrome; Dehydroepiandrostero

1991
Basal serum dehydroepiandrosterone sulphate concentration does not predict the cortisol response to provocative testing.
    Annals of clinical biochemistry, 1990, Volume: 27 ( Pt 6)

    Topics: Adolescent; Adult; Aged; Cushing Syndrome; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; F

1990
Marked elevation of serum dehydroepiandrosterone sulphate in Cushing's disease with macronodular adrenocortical hyperplasia.
    Journal of endocrinological investigation, 1989, Volume: 12, Issue:4

    Topics: Adrenal Cortex Diseases; Adult; Cushing Syndrome; Dehydroepiandrosterone; Dehydroepiandrosterone Sul

1989
Decreased dehydroepiandrosterone sulfate in pigmented nodular adrenal dysplasia.
    Clinical chemistry, 1989, Volume: 35, Issue:11

    Topics: Adrenal Glands; Adult; Cushing Syndrome; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Fem

1989
[Clinical significance of serum dehydroepiandrosterone and dehydroepiandrosterone sulfate analysis in endocrine tests of the adrenal cortex].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 48 Suppl

    Topics: Adrenal Hyperplasia, Congenital; Age Factors; Aged; Aged, 80 and over; Circadian Rhythm; Cushing Syn

1989
Mechanism of dissociation of cortisol and adrenal androgen secretion after removal of adrenocortical adenoma in patients with Cushing's syndrome.
    Endocrinologia japonica, 1985, Volume: 32, Issue:5

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Atrophy; Cells, Cultured;

1985
Steroid content of the peripheral and adrenal vein in Cushing's syndrome due to adrenocortical adenoma and carcinoma.
    The Journal of urology, 1988, Volume: 140, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Androstened

1988
Use of ketoconazole in the treatment of Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 63, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Cushing

1986
Adrenocortical carcinoma with Cushing's syndrome presenting unusual urinary 17-ketosteroid fractionation.
    Journal of endocrinological investigation, 1985, Volume: 8, Issue:3

    Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adult; Androstenedione; And

1985
A modified method for the analysis of urinary 17-ketosteroids, pregnanediol and pregnanetriol by gas liquid chromatography in normal subjects and subjects with various endocrine disorders.
    Acta endocrinologica, 1967, Volume: 54, Issue:1

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Androsterone; Chromatography, Gas; Cushing Syndrom

1967
Urinary testosterone fractions. Studies on the origin in certain diseases associated with elevated testosterone excretion.
    American journal of obstetrics and gynecology, 1967, Oct-15, Volume: 99, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Cushing Syndrome; Dehydroepiandr

1967
[Pattern of urinary neutral 17-ketosteroids on the basis of thin layer chromatography].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1967, Volume: 5, Issue:4

    Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adult; Androstan

1967
Abnormal lactation with Cushing's syndrome--a case report.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:7

    Topics: 17-Ketosteroids; Adult; Androsterone; Chemistry, Clinical; Chiari-Frommel Syndrome; Cushing Syndrome

1969
A time study of the in vitro metabolism of 3 beta-hydroxyandrost-5-en-17-one by human adrenocortical tissue.
    Steroids, 1969, Volume: 14, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Chromatography, Gas; Cushing Syndrome; Dehydroepia

1969
A comparative study of steroid biosyntheses in vitro. In clear cell adenoma and its adjacent tissue of human adrenal gland.
    Endocrinologia japonica, 1969, Volume: 16, Issue:1

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Carbon Isotopes; C

1969
Menstrual disorders associated with adrenal dysfunction.
    Clinical obstetrics and gynecology, 1969, Volume: 12, Issue:3

    Topics: 17-Ketosteroids; Addison Disease; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands;

1969
[Gas chromatography determination of urinary pregnanediol and -triol and its significance for the differentiation of adrenal hirsutism in women].
    Endokrinologie, 1969, Volume: 54, Issue:5

    Topics: 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Adult; C

1969
[Metabolism of steroids in normal and pathological human adrenal glands].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1971, Volume: 62, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Glands; Adult; Androgens; Carbo

1971
The determination of urinary pregnanetriol and the neutral 17-ketosteroids by gas-liquid chromatography.
    Steroids, 1971, Volume: 18, Issue:2

    Topics: 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adre

1971
The routine measurement of urinary 17-oxosteroids and 17-oxogenic steroids using gas-liquid chromatography.
    Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 40, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adult; Androgens; Androsterone; Chromat

1972
Excretion patterns of urinary 17-KS and 17-OHCS in patients with Cushing's syndrome.
    Urologia internationalis, 1974, Volume: 29, Issue:5

    Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal

1974
+On a procedure for determination of the adrenal cortex secreion rate of cortisol and dehydroepiandrosterone.
    Nuclear-Medizin, 1965

    Topics: Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Cushing Syndrome;

1965
[Gas liquid chromatography analysis of urinary neutral steroid fractions in normal persons and patients with various diseases].
    Nihon Naibunpi Gakkai zasshi, 1970, Jun-20, Volume: 46, Issue:3

    Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormon

1970
Cushing's syndrome caused by malignant tumor in the scrotum: clinical, pathologic and biochemical studies.
    The Journal of clinical endocrinology and metabolism, 1971, Volume: 32, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Rest Tumor; Adrenocorticotropic Hormone; Androst

1971
Rapid gas chromatographic assay for dehydroepiandrosterone in urine.
    Clinical biochemistry, 1971, Volume: 4, Issue:4

    Topics: Adolescent; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Chorionic Gonadotropi

1971
An unusual case of Cushing's syndrome, hilus cell tumor and polycystic ovaries.
    The Journal of clinical endocrinology and metabolism, 1974, Volume: 38, Issue:5

    Topics: Adolescent; Adrenalectomy; Adrenocorticotropic Hormone; Child; Cushing Syndrome; Dehydroepiandroster

1974