dehydroepiandrosterone has been researched along with Crohn Disease in 2 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with dehydroepiandrosterone was effective in randomized controlled trials in patients with systemic lupus erythematosus." | 2.71 | Patients with refractory Crohn's disease or ulcerative colitis respond to dehydroepiandrosterone: a pilot study. ( Andus, T; Bregenzer, N; Klebl, F; Rogler, G; Schölmerich, J; Straub, RH, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andus, T | 1 |
| Klebl, F | 1 |
| Rogler, G | 1 |
| Bregenzer, N | 1 |
| Schölmerich, J | 1 |
| Straub, RH | 1 |
| Osathanondh, R | 1 |
| Fencl, MD | 1 |
| Schiff, I | 1 |
| Himmel, M | 1 |
| Tulchinsky, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blind, Multi-Center, Dose Response, Efficacy and Safety Evaluation of Inflabloc Cap in the Treatment of Patients With Moderately Active Crohn's Disease[NCT00106314] | Phase 2 | 75 participants | Interventional | 2005-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for dehydroepiandrosterone and Crohn Disease
| Article | Year |
|---|---|
Patients with refractory Crohn's disease or ulcerative colitis respond to dehydroepiandrosterone: a pilot study.
Topics: Adjuvants, Immunologic; Adult; Chronic Disease; Colitis, Ulcerative; Crohn Disease; Dehydroepiandros | 2003 |
1 other study available for dehydroepiandrosterone and Crohn Disease
| Article | Year |
|---|---|
Reduced urinary and serum total estriol levels in pregnancies after colectomy.
Topics: Adrenal Glands; Adult; Colectomy; Colitis, Ulcerative; Crohn Disease; Dehydroepiandrosterone; Entero | 1979 |