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dehydroepiandrosterone and Coronary Disease

dehydroepiandrosterone has been researched along with Coronary Disease in 32 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"The clinical significance of dehydroepiandrosterone (DHEA) and its sulphate (DHEAS) in coronary heart disease (CHD) has not been thoroughly elucidated to date."5.01Association of endogenous DHEA/DHEAS with coronary heart disease: A systematic review and meta-analysis. ( Gao, Y; Ma, YT; Wu, TT; Xie, X; Zheng, YY, 2019)
"Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone-sulfate (DHEAS), the major androgens secreted by human adrenal glands, were suggested to play a protective role in the pathogenesis of atherosclerosis and coronary heart disease."4.80Do DHEA/DHEAS play a protective role in coronary heart disease? ( Porsová-Dutoit, I; Stárka, L; Sulcová, J, 2000)
"Published studies dealing with the relationship between circulating levels of testosterone and dehydroepiandrosterone (sulfate) (DHEA(S)) and coronary heart disease (CHD) in males, as well as corresponding experimental animal studies are reviewed."4.79The relationship of natural androgens to coronary heart disease in males: a review. ( Alexandersen, P; Christiansen, C; Haarbo, J, 1996)
"It has been postulated that dehydroepiandrosterone (DHEA) and its sulfate ester, dehydroepiandrosterone sulfate (DHEAS), the major secretory products of the human adrenal gland, may be discriminators of life expectancy and aging."3.67A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease. ( Barrett-Connor, E; Khaw, KT; Yen, SS, 1986)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199014 (43.75)18.7374
1990's9 (28.13)18.2507
2000's2 (6.25)29.6817
2010's7 (21.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, H1
Li, Y1
Wang, X1
Bu, J1
Yan, G1
Lou, D1
Wu, TT1
Gao, Y1
Zheng, YY1
Ma, YT1
Xie, X1
Sutton, NR1
Pinsky, DJ1
Tivesten, Å2
Vandenput, L2
Carlzon, D1
Nilsson, M1
Karlsson, MK1
Ljunggren, Ö1
Barrett-Connor, E3
Mellström, D1
Ohlsson, C2
Klevay, LM1
Shufelt, C1
Braunstein, GD1
Pepine, CJ1
Bairey Merz, CN1
Kaufman, JM1
Vermeulen, A1
Milani, RV1
Lavie, CJ1
Barbee, RW1
Littman, AB2
Słowińska-Srzednicka, J1
Malczewska, B1
Srzednicki, M2
Chotkowska, E2
Brzezińska, A1
Zgliczyński, W2
Ossowski, M1
Jeske, W1
Zgliczyński, S2
Sadowski, Z1
Hautanen, A1
Mänttäri, M1
Manninen, V1
Tenkanen, L1
Huttunen, JK1
Frick, MH1
Adlercreutz, H1
Geisthövel, F1
Olbrich, M1
Frorath, B1
Thiemann, M1
Weitzell, R1
Fava, M4
Halperin, P3
Lamon-Fava, S2
Drews, FR1
Oleshansky, MA1
Bielenda, CC1
MacLaughlin, RA1
Alexandersen, P1
Haarbo, J1
Christiansen, C1
Porsová-Dutoit, I1
Sulcová, J1
Stárka, L1
Lopez-S, A1
Wingo, C1
Hebert, JA1
Sonka, J1
Anisimov, VE1
Marenich, LP1
Littman, A3
Milani, R1
Shera, D1
MacLaughlin, R1
Cassem, E1
Leaf, A1
Marchiò, B1
Bolognesi, E1
Slowinska-Srzednicka, J1
Soszynski, P1
Makowska, A1
Bednarska, M1
Woroszylska, M1
Ruzyllo, W1
Amemiya, T1
Kawahara, R1
Yoshino, M1
Komori, K1
Hirata, Y1
Khaw, KT1
Yen, SS1
Sznajderman, M2
Zaretskiĭ, MM2
Vakhtina, TI2
Miasnikov, LA2
Miasnikova, NV1
Vinogradova, DA2
Spivak, RIa1
Argüelles, AE1
Martínez, MA1
Hoffman, C1
Ortiz, GA1
Chekherdemian, M1

Reviews

7 reviews available for dehydroepiandrosterone and Coronary Disease

ArticleYear
Endogenous sex hormone levels and coronary heart disease risk in postmenopausal women: A meta-analysis of prospective studies.
    European journal of preventive cardiology, 2017, Volume: 24, Issue:6

    Topics: Aged; Aged, 80 and over; Biomarkers; Coronary Disease; Dehydroepiandrosterone; Estradiol; Female; Go

2017
Association of endogenous DHEA/DHEAS with coronary heart disease: A systematic review and meta-analysis.
    Clinical and experimental pharmacology & physiology, 2019, Volume: 46, Issue:11

    Topics: Coronary Disease; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans

2019
The decline of androgen levels in elderly men and its clinical and therapeutic implications.
    Endocrine reviews, 2005, Volume: 26, Issue:6

    Topics: Aged; Aging; Androgens; Atherosclerosis; Clinical Trials as Topic; Coronary Disease; Dehydroepiandro

2005
The relationship of natural androgens to coronary heart disease in males: a review.
    Atherosclerosis, 1996, Aug-23, Volume: 125, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; Case-Control Studies; Chickens; Cohort Studies; Coronary Di

1996
Do DHEA/DHEAS play a protective role in coronary heart disease?
    Physiological research, 2000, Volume: 49 Suppl 1

    Topics: Animals; Coronary Disease; Cross-Sectional Studies; Dehydroepiandrosterone; Dehydroepiandrosterone S

2000
[Hyperuricemia and arteriosclerosis].
    Klinicheskaia meditsina, 1978, Volume: 56, Issue:1

    Topics: Adult; Arteriosclerosis; Coronary Disease; Dehydroepiandrosterone; Female; Gout; Humans; Hyperlipide

1978
Neuroendocrine correlates of the type A behavior pattern: a review and new hypotheses.
    International journal of psychiatry in medicine, 1987, Volume: 17, Issue:4

    Topics: Arousal; Coronary Disease; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hormones; Humans;

1987

Trials

1 trial available for dehydroepiandrosterone and Coronary Disease

ArticleYear
Adrenal androgens and testosterone as coronary risk factors in the Helsinki Heart Study.
    Atherosclerosis, 1994, Volume: 105, Issue:2

    Topics: Adrenal Glands; Age Factors; Androgens; Androstane-3,17-diol; Androstenedione; Blood Pressure; Case-

1994

Other Studies

24 other studies available for dehydroepiandrosterone and Coronary Disease

ArticleYear
Sex steroid as a new oracle to predict cardiovascular risk.
    Journal of the American College of Cardiology, 2014, Oct-28, Volume: 64, Issue:17

    Topics: Coronary Disease; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Male

2014
Dehydroepiandrosterone and its sulfate predict the 5-year risk of coronary heart disease events in elderly men.
    Journal of the American College of Cardiology, 2014, Oct-28, Volume: 64, Issue:17

    Topics: Aged; Aged, 80 and over; Chromatography, Gas; Chromatography, Liquid; Coronary Disease; Dehydroepian

2014
Copper, coronary heart disease, and dehydroepiandrosterone.
    Journal of the American College of Cardiology, 2015, May-19, Volume: 65, Issue:19

    Topics: Coronary Disease; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Male

2015
Recognizing Sex Similarities in Cardiovascular Disease Research.
    Journal of the American College of Cardiology, 2015, May-19, Volume: 65, Issue:19

    Topics: Coronary Disease; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Male

2015
Reply: Recognizing Sex Similarities in Cardiovascular Disease Research Copper, Coronary Heart Disease, and Dehydroepiandrosterone.
    Journal of the American College of Cardiology, 2015, May-19, Volume: 65, Issue:19

    Topics: Coronary Disease; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Male

2015
Lack of effect of exercise training on dehydroepiandrosterone-sulfate.
    The American journal of the medical sciences, 1995, Volume: 310, Issue:6

    Topics: Aged; Behavior; Coronary Disease; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Exercise T

1995
Hyperinsulinaemia and decreased plasma levels of dehydroepiandrosterone sulfate in premenopausal women with coronary heart disease.
    Journal of internal medicine, 1995, Volume: 237, Issue:5

    Topics: Adult; Coronary Angiography; Coronary Disease; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfat

1995
Obesity and hypertestosteronaemia are independently and synergistically associated with elevated insulin concentrations and dyslipidaemia in pre-menopausal women.
    Human reproduction (Oxford, England), 1994, Volume: 9, Issue:4

    Topics: Adult; Body Mass Index; Coronary Disease; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Fe

1994
Physiologic benefits of a stress reduction program for healthy middle-aged Army officers.
    Journal of psychosomatic research, 1993, Volume: 37, Issue:4

    Topics: Adult; Arousal; Behavior Therapy; Coronary Disease; Dehydroepiandrosterone; Dehydroepiandrosterone S

1993
Total serum cholesterol and urinary dehydroepiandrosterone in humans.
    Atherosclerosis, 1976, Volume: 24, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Body Height; Body Weight; Child; Cholesterol; Coronary Disease

1976
Dehydroepiandrosterone. Metabolic effects.
    Acta Universitatis Carolinae. Medica. Monographia, 1976, Volume: 71

    Topics: Adolescent; Adult; Androgens; Animals; Cell Division; Cell Membrane Permeability; Chemical Phenomena

1976
[Effect of chorionic gonadotropin on the urinary excretion of testosterone and other androgens in healthy men and those with coronary arteriosclerosis].
    Kardiologiia, 1979, Volume: 19, Issue:6

    Topics: Adult; Androgens; Androstenedione; Blood Coagulation; Chorionic Gonadotropin; Coronary Disease; Dehy

1979
Psychological, behavioral and biochemical risk factors for coronary artery disease among American and Italian male corporate managers.
    The American journal of cardiology, 1992, Dec-01, Volume: 70, Issue:18

    Topics: Administrative Personnel; Adult; Apolipoprotein A-I; Attitude; Coronary Disease; Dehydroepiandroster

1992
Decreased plasma levels of dehydroepiandrosterone sulphate (DHEA-S) in normolipidaemic and hyperlipoproteinaemic young men with coronary artery disease.
    Journal of internal medicine, 1991, Volume: 230, Issue:6

    Topics: Adult; Coronary Disease; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hyperlipopr

1991
Population study on the adipose tissue distribution in Japanese women born in 1948.
    Diabetes research and clinical practice, 1990, Volume: 10 Suppl 1

    Topics: Adipose Tissue; Adult; Androstenedione; Body Composition; Coronary Disease; Dehydroepiandrosterone;

1990
A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease.
    The New England journal of medicine, 1986, Dec-11, Volume: 315, Issue:24

    Topics: Aged; Aging; Analysis of Variance; Cardiovascular Diseases; Coronary Disease; Dehydroepiandrosterone

1986
Dehydroepiandrosterone sulfate, mortality, and cardiovascular disease.
    The New England journal of medicine, 1987, Jun-11, Volume: 316, Issue:24

    Topics: Coronary Disease; Dehydroepiandrosterone; Humans

1987
[Excretion of neutral 17-ketosteroids and their fractions in men suffering from coronary heart disease].
    Polskie Archiwum Medycyny Wewnetrznej, 1967, Volume: 39, Issue:6

    Topics: 17-Ketosteroids; Adult; Androsterone; Coronary Disease; Dehydroepiandrosterone; Etiocholanolone; Hum

1967
Urinary excretion of neutral 17-ketosteroids and their fractions in men with coronary heart disease.
    Polish medical journal, 1968, Volume: 7, Issue:6

    Topics: 17-Ketosteroids; Adult; Age Factors; Androsterone; Arteriosclerosis; Coronary Disease; Dehydroepiand

1968
[Protein composition of the blood and excretion of corticosteroids in patients with arteriosclerotic cardiosclerosis with chronic circulatory insufficiency].
    Kardiologiia, 1969, Volume: 9, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Blood Proteins; Coronary Diseas

1969
[Status of metabolism of cortisone and androgens in patients with atherosclerosis].
    Kardiologiia, 1970, Volume: 10, Issue:2

    Topics: 17-Ketosteroids; Adrenal Glands; Adult; Androgens; Androsterone; Arteriosclerosis; Chromatography, T

1970
[Estrogens and androgens in dyshormonal cardiopathy and coronary atherosclerosis in women].
    Kardiologiia, 1971, Volume: 11, Issue:9

    Topics: 17-Ketosteroids; Adult; Androgens; Androsterone; Arteriosclerosis; Chromatography, Thin Layer; Coron

1971
Androgen function of the adrenal cortex in patients with arteriosclerotic cardiosclerosis.
    Kardiologiia, 1971, Volume: 11, Issue:6

    Topics: Adrenal Glands; Adult; Aged; Androgens; Androsterone; Chromatography, Thin Layer; Coronary Disease;

1971
Corticoadrenal and adrenergic overactivity and hyperlipidemia in prolonged emotional stress.
    Hormones, 1972, Volume: 3, Issue:3

    Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adult; Catech

1972