Page last updated: 2024-11-07

dehydroepiandrosterone and Congenital Adrenal Hyperplasia

dehydroepiandrosterone has been researched along with Congenital Adrenal Hyperplasia in 145 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
"To assess whether patients with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency exhibit a steroidogenic response to GnRH agonist consistent with functional ovarian hyperandrogenism (FOH) and elucidate the relationship between adrenal and ovarian hyperandrogenism, the LH, FSH, estradiol, 17-hydroxyprogesterone (17-OHP), androstenedione, total testosterone, dehydroepiandrosterone, and 17-hydroxypregnenolone responses to a sc dose of leuprolide acetate (500 micrograms) were evaluated in 10 patients with classic CAH (mean age, 18."7.69Pituitary-ovarian responses to leuprolide acetate testing in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. ( Bernasconi, S; Cappa, M; Ghizzoni, L; Ibañez, L; Street, ME; Virdis, R; Vottero, A; Zampolli, M, 1996)
"To determine whether measurements of plasma dehydroepiandrosterone (DHEA) sulfate and ACTH stimulation tests, both widely used in the evaluation of hirsutism in women, provide useful information, we performed both tests in 22 normal women and 31 female patients with hirsutism."7.68ACTH stimulation tests and plasma dehydroepiandrosterone sulfate levels in women with hirsutism. ( Finegold, DN; Lanes, R; Lee, PA; Siegel, SF, 1990)
"The practicability and tolerability of trilostane, a competitive inhibitor of 3 beta-hydroxysteroid-delta 5-dehydrogenase, for the therapy of primary aldosteronism was assessed in 1 patient with aldosterone-producing adenoma (APA) and 3 subjects with idiopathic adrenal hyperplasia (IHA)."7.67Primary aldosteronism treated by trilostane (3 beta-hydroxysteroid dehydrogenase inhibitor). ( Ishikawa, S; Katayama, T; Kazama, T; Koike, H; Nakada, T; Yoshikawa, M, 1985)
"Serum concentrations of dehydroepiandrosterone sulfate (DHEAS) were measured in 28 patients (18 females, 10 males) with congenital adrenal hyperplasia due to 21-hydroxylase deficiency who were treated with oral hydrocortisone (non-salt losers) or hydrocortisone and 9-alpha-fluorohydrocortisone (salt-losers)."7.66Disproportionate suppression of dehydroepiandrosterone sulfate (DHEAS) in treated patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. ( Artman, HG; Digeorge, AM; Garibaldi, LR; Rezvani, I, 1983)
"The effects of prednisone therapy and the withdrawal of prednisone for 3 days on hormonal relationships was investigated in 6 adolescent patients, age 10--19 years with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency."7.66Hormonal and clinical responses to prednisone treatment in adolescents with congenital adrenal hyperplasia. ( Bacon, GE; Kelch, RP; Zipf, WB, 1980)
"Treatment outcome in congenital adrenal hyperplasia is often suboptimal due to hyperandrogenism, treatment-induced hypercortisolism, or both."6.68A preliminary study of flutamide, testolactone, and reduced hydrocortisone dose in the treatment of congenital adrenal hyperplasia. ( Barnes, KM; Cutler, GB; Hill, S; Jones, JV; Laue, L; Merke, DP, 1996)
"Non-classic congenital adrenal hyperplasia (NC-CAH), one of the most common genetic disorders, is often associated with the clinical features of hyperandrogenism."5.40The effect of metformin on androgen production in diabetic women with non-classic congenital adrenal hyperplasia. ( Krysiak, R; Okopien, B, 2014)
"Non-classic congenital adrenal hyperplasia (NC-CAH) is one of the most frequent genetic disorders and its presence often results in androgen excess."5.39The effect of simvastatin treatment on plasma steroid levels in females with non-classic congenital adrenal hyperplasia. ( Krysiak, R; Okopien, B, 2013)
" The frequency of obesity and the correlation between dehydroepiandrosterone sulphate levels and body mass index suggest that body weight is involved in the onset of adrenarche."3.72Premature pubarche as an indicator of how body weight influences the onset of adrenarche. ( Brauner, R; Charkaluk, ML; Trivin, C, 2004)
"Dehydroepiandrosterone sulfate (DHEAS) concentration levels were measured by a specific RIA in 23 female and 7 male patients with classical congenital adrenal hyperplasia (CAH) salt-losing type due to steroid 21-hydroxylase (21-OH) deficiency."3.69Blunted adrenarche in patients with classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency. ( MacGillivray, MH; Sellers, EP, 1995)
"To assess whether patients with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency exhibit a steroidogenic response to GnRH agonist consistent with functional ovarian hyperandrogenism (FOH) and elucidate the relationship between adrenal and ovarian hyperandrogenism, the LH, FSH, estradiol, 17-hydroxyprogesterone (17-OHP), androstenedione, total testosterone, dehydroepiandrosterone, and 17-hydroxypregnenolone responses to a sc dose of leuprolide acetate (500 micrograms) were evaluated in 10 patients with classic CAH (mean age, 18."3.69Pituitary-ovarian responses to leuprolide acetate testing in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. ( Bernasconi, S; Cappa, M; Ghizzoni, L; Ibañez, L; Street, ME; Virdis, R; Vottero, A; Zampolli, M, 1996)
" The degree of hirsutism, the menstrual abnormalities and the level of 17-ketosteroids, of DHEA, of 17-OH-corticoids in urine and RIA of total and free testosterone and of sex binding globulins (SHBG) in blood were performed."3.68[Endocrine and ultrasound examination of hirsutism]. ( Baron, JJ, 1991)
"To determine whether measurements of plasma dehydroepiandrosterone (DHEA) sulfate and ACTH stimulation tests, both widely used in the evaluation of hirsutism in women, provide useful information, we performed both tests in 22 normal women and 31 female patients with hirsutism."3.68ACTH stimulation tests and plasma dehydroepiandrosterone sulfate levels in women with hirsutism. ( Finegold, DN; Lanes, R; Lee, PA; Siegel, SF, 1990)
"We investigated the value of serum levels of adrenal steroids (dehydroepiandrosterone sulphate, testosterone, 17-hydroxyprogesterone, cortisol) in the identification in peripubertal females with late-onset congenital adrenal hyperplasia owing to 21-hydroxylase deficiency."3.67Detection of late-onset adrenal hyperplasia in girls with peripubertal virilization. ( Gács, G; Keszei, K; Láng, K; Orley, J; Petheö, I; Ságodi, L; Sólyom, J, 1987)
"The practicability and tolerability of trilostane, a competitive inhibitor of 3 beta-hydroxysteroid-delta 5-dehydrogenase, for the therapy of primary aldosteronism was assessed in 1 patient with aldosterone-producing adenoma (APA) and 3 subjects with idiopathic adrenal hyperplasia (IHA)."3.67Primary aldosteronism treated by trilostane (3 beta-hydroxysteroid dehydrogenase inhibitor). ( Ishikawa, S; Katayama, T; Kazama, T; Koike, H; Nakada, T; Yoshikawa, M, 1985)
"Serum concentrations of dehydroepiandrosterone sulfate (DHEAS) were measured in 28 patients (18 females, 10 males) with congenital adrenal hyperplasia due to 21-hydroxylase deficiency who were treated with oral hydrocortisone (non-salt losers) or hydrocortisone and 9-alpha-fluorohydrocortisone (salt-losers)."3.66Disproportionate suppression of dehydroepiandrosterone sulfate (DHEAS) in treated patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. ( Artman, HG; Digeorge, AM; Garibaldi, LR; Rezvani, I, 1983)
" Based on their experience, the authors suggest an inexpensive investigative strategy in hyperandrogenic females consisting of the following: the first step depends upon the clinical symptoms--in cases of hirsutism with regular menstrual cycles, plasma testosterone (T) and plasma dehydroepiandrosterone sulfate (DHA-S) are assayed, and the basal body temperature chart is recorded."3.66Investigative strategy of hyperandrogenism in women. ( Buvat, J; Buvat-Herbaut, M; Dewailly, D; Fossati, P; Marcolin, G; Racadot, A, 1983)
"Plasma levels of dehydroepiandrosterone-sulfate (DHEA-S), dehydroepiandrosterone (DHEA), delta 4-androstenedione (delta 4), testosterone and 17 alpha-OH-progesterone (17-OH-P) were studied in 58 samples collected in 18 patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency, during long-term ambulatory treatment with hydrocortisone."3.66Plasma levels of androgens and 17 alpha-OH-progesterone as an index of the adequacy of treatment in congenital adrenal hyperplasia. ( Eeckels, R; Eggermont, E; Ilondo, MM; Malvaux, P; Pizarro, M; Vanderschueren-Lodeweyckx, M; Vlietinck, R, 1983)
"Serum androgen levels, including dehydroepiandrosterone sulphate (DHAS) which is thought to be solely of adrenal origin, are elevated in women with the polycystic ovarian syndrome."3.66Acth function in women with the polycystic ovarian syndrome. ( Butt, WR; Holder, G; Horrocks, PM; Kandeel, FR; Logan-Edwards, R; London, DR; Lynch, SS, 1983)
"The effects of prednisone therapy and the withdrawal of prednisone for 3 days on hormonal relationships was investigated in 6 adolescent patients, age 10--19 years with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency."3.66Hormonal and clinical responses to prednisone treatment in adolescents with congenital adrenal hyperplasia. ( Bacon, GE; Kelch, RP; Zipf, WB, 1980)
"Treatment outcome in congenital adrenal hyperplasia is often suboptimal due to hyperandrogenism, treatment-induced hypercortisolism, or both."2.68A preliminary study of flutamide, testolactone, and reduced hydrocortisone dose in the treatment of congenital adrenal hyperplasia. ( Barnes, KM; Cutler, GB; Hill, S; Jones, JV; Laue, L; Merke, DP, 1996)
" Chronic administration of long acting GnRH agonists (GnRHa), like continuous infusion of high doses of the native peptide, results in suppression of pituitary gonadotropin secretion."2.37Use of a potent, long acting agonist of gonadotropin-releasing hormone in the treatment of precocious puberty. ( Bode, HH; Boepple, PA; Crawford, JD; Crigler, JF; Crowley, WF; Mansfield, MJ; Rudlin, CR; Wierman, ME, 1986)
"We present a female patient with congenital adrenal hyperplasia detected in newborn screening due to elevated 17OH-progesterone."1.43Non-Virilizing Congenital Adrenal Hyperplasia in a Female Patient with a Novel HSD3B2 Mutation. ( Camats, N; Flück, CE; l'Allemand, D; Probst-Scheidegger, U; Udhane, SS, 2016)
"The treatment goal in congenital adrenal hyperplasia (CAH) is to replace glucocorticoids while avoiding androgen excess and iatrogenic Cushing's syndrome."1.42Hormonal circadian rhythms in patients with congenital adrenal hyperplasia: identifying optimal monitoring times and novel disease biomarkers. ( Backlund, PS; Crutchfield, CA; Debono, M; Gounden, V; Harrison, RF; Mallappa, A; Merke, DP; Nella, AA; Ross, RJ; Soldin, SJ, 2015)
"Non-classic congenital adrenal hyperplasia (NC-CAH), one of the most common genetic disorders, is often associated with the clinical features of hyperandrogenism."1.40The effect of metformin on androgen production in diabetic women with non-classic congenital adrenal hyperplasia. ( Krysiak, R; Okopien, B, 2014)
"Non-classic congenital adrenal hyperplasia (NC-CAH) is one of the most frequent genetic disorders and its presence often results in androgen excess."1.39The effect of simvastatin treatment on plasma steroid levels in females with non-classic congenital adrenal hyperplasia. ( Krysiak, R; Okopien, B, 2013)
"Some research suggests that girls with congenital adrenal hyperplasia (CAH), who are exposed to higher than normal levels of prenatal androgens, perform better on spatial tasks, worse on verbal tasks and have a greater incidence of left-handedness than unaffected controls, all of which suggests the development of a more male-typical cognitive pattern."1.33Cognitive outcome in adult women affected by congenital adrenal hyperplasia due to 21-hydroxylase deficiency. ( Carson, KA; Malouf, MA; Migeon, CJ; Petrucci, L; Wisniewski, AB, 2006)
"Testicular tumors are very rare in boys, approximately 1."1.31[Precocious puberty caused by a testicular Leydig cell tumor]. ( Borbás, E; Minik, K; Réti, G; Ságodi, L; Sólyom, E, 2001)
"Late-onset congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency has been reported with increasing frequency, but only a few adult women have been found to have this disorder in Japan."1.29A case of late-onset congenital adrenal hyperplasia due to partial 3 beta-hydroxysteroid dehydrogenase deficiency. ( Hattori, N; Hino, M; Ikekubo, K; Ishihara, T; Kurahachi, H; Moridera, K, 1993)
"The patient was diagnosed with congenital adrenal hyperplasia (CAH) and received hormone therapy."1.29Hormonal and genetic analysis of a patient with congenital adrenal hyperplasia. ( Herold, DA; Seely, BL; Summers, RH, 1996)
"When dehydroepiandrosterone was used as substrate, the Km value for G129R3 beta HSD was 14 +/- 2 mumol/L compared with 2."1.29Molecular basis of congenital adrenal hyperplasia in two siblings with classical nonsalt-losing 3 beta-hydroxysteroid dehydrogenase deficiency. ( Chang, YT; Labrie, F; Pang, S; Rhéaume, E; Sanchez, R; Simard, J; Wang, J, 1994)
"We present an unusual patient with a Leydig cell tumor to show that greatly elevated serum concentrations of 17-hydroxyprogesterone (17OHP) may not be diagnostic of congenital adrenal hyperplasia (CAH)."1.28Molecular characterization of a Leydig cell tumor presenting as congenital adrenal hyperplasia. ( Goldsmith, MA; Miller, WL; Solish, SB; Voutilainen, R, 1989)
"The occurrence of nonclassical congenital adrenal hyperplasia among children with precocious pubarche is still a matter of debate."1.28Adrenal steroidogenic defects in children with precocious pubarche. ( Borrelli, P; Cambiaso, P; Cappa, M; Danielli, E; del Balzo, P, 1992)
"The male pseudohermaphroditism resulted from deficient testosterone synthesis due to deficiency of 17 alpha-hydroxylase and 17,20 desmolase."1.27Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases. A new variant of congenital adrenal hyperplasia. ( Gautier, T; Imperato-McGinley, J; Peterson, RE; Shackleton, C, 1985)
"In four patients with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase (21-OHase) deficiency, ASI and plasma concentrations of pre-defect steroid were determined."1.27Age-related changes in adrenal size during the first year of life in normal newborns, infants and patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency: comparison of ultrasound and hormonal parameters. ( Hauffa, BP; Menzel, D; Stolecke, H, 1988)

Research

Studies (145)

TimeframeStudies, this research(%)All Research%
pre-199079 (54.48)18.7374
1990's41 (28.28)18.2507
2000's11 (7.59)29.6817
2010's13 (8.97)24.3611
2020's1 (0.69)2.80

Authors

AuthorsStudies
Jing, H1
Ding, Y1
Jiang, X1
Liu, G1
Sha, Y1
Medeiros, SF1
Gil-Junior, AB1
Barbosa, JS1
Isaías, ED1
Yamamoto, MM1
Krysiak, R2
Okopien, B2
Turcu, AF1
Auchus, RJ3
Debono, M1
Mallappa, A1
Gounden, V2
Nella, AA1
Harrison, RF1
Crutchfield, CA1
Backlund, PS1
Soldin, SJ2
Ross, RJ1
Merke, DP3
Stolze, BR1
Gu, J1
Elliott, EA1
Masika, LS1
Abel, BS1
Skarulis, MC1
Probst-Scheidegger, U1
Udhane, SS1
l'Allemand, D1
Flück, CE1
Camats, N1
Khoury, K1
Barbar, E1
Ainmelk, Y1
Ouellet, A1
Lehoux, JG1
Lee, CT1
Tung, YC1
Hsiao, PH1
Lee, JS1
Tsai, WY1
Chang, AY1
Ashida, K1
Akehi, Y1
Kudo, T1
Yanase, T1
Ghayee, HK1
Rege, J1
Watumull, LM1
Nwariaku, FE1
Carrick, KS1
Rainey, WE1
Miller, WL5
Kamrath, C1
Hartmann, MF1
Wudy, S1
Oswiecimska, JM1
Ksiazek, A1
Sygulla, K1
Pys-Spychala, M1
Roczniak, GR1
Roczniak, W1
Stojewska, M1
Ziora, K1
Cutolo, M1
Sulli, A1
Pizzorni, C1
Craviotto, C1
Prete, C1
Foppiani, L1
Salvarani, C1
Straub, RH1
Seriolo, B1
NATOLI, A1
MAGLIOCCA, R1
GOLDZIEHER, JW1
DIGNAM, WJ1
PION, RJ1
LAMB, EJ1
SIMMER, HH1
VILLEE, DB1
SORCINI, G1
SCIARRA, F1
CONCOLINO, G1
RASCIO, L1
MORTIMER, JG1
RUDD, BT1
BUTT, WR2
ROSNER, JM1
CONTE, NF1
BRIGGS, JH1
CHAO, PY1
SUDMAN, EM1
FORSHAM, PH1
Charkaluk, ML1
Trivin, C1
Brauner, R1
Goto, K1
Nawata, H2
Malouf, MA1
Migeon, CJ3
Carson, KA1
Petrucci, L1
Wisniewski, AB1
Fanta, M1
Cibula, D1
Vrbíková, J1
Riad-Fahmy, D1
Read, GF1
Walker, RF1
Griffiths, K1
Rezvani, I1
Garibaldi, LR2
Digeorge, AM1
Artman, HG1
Braithwaite, SS1
Jabamoni, R1
Buvat, J1
Dewailly, D3
Marcolin, G1
Buvat-Herbaut, M1
Racadot, A2
Fossati, P2
Ilondo, MM1
Vanderschueren-Lodeweyckx, M1
Pizarro, M1
Vlietinck, R1
Malvaux, P1
Eggermont, E1
Eeckels, R1
Check, JH1
Krotec, JW1
Roger, M1
Chaussain, JL1
Evain, D1
Toublanc, JE1
Canlorbe, P1
Scholler, R1
Tóth, I1
Faredin, I1
Zacharías, S1
Contreras, P1
New, MI8
Levine, LS8
Dupont, B3
Lorenzen, F3
Pang, S7
Pollack, M2
Oberfield, SE2
Kohn, B2
Lerner, A2
Cacciari, E3
Mantero, F2
Cassio, A2
Scaroni, C2
Chiumello, G3
Rondanini, GF2
Gargantini, L2
Giovannelli, G2
Virdis, R4
Bartolotta, E2
Migliori, C2
Pintor, C2
Tato, L2
Barboni, F2
Horrocks, PM2
London, DR2
Kandeel, FR1
Lynch, SS1
Holder, G1
Logan-Edwards, R1
Gangemi, M1
Benato, M1
Guacci, AM1
Meneghetti, G1
Zipf, WB1
Bacon, GE1
Kelch, RP1
Cederqvist, LL1
Fuentes, M1
Riccardi, VM1
Holcombe, JH2
Nitowsky, HM1
Sachs, G1
Anderson, CE1
Duchon, MA1
Owens, R1
Merkatz, I1
Oberfield, S1
Elias, AN1
Grossman, MK1
Meshkinpour, H1
Valenta, LJ1
Bernick, D1
Mauvais-Jarvis, P1
Kuttenn, F1
Mowszowicz, I1
de Peretti, E1
Forest, MG2
Sellers, EP1
MacGillivray, MH1
Ibáñez, L2
Bonnin, MR1
Zampolli, M2
Prat, N1
Alia, PJ1
Navarro, MA1
Brunelli, VL1
David, M1
Likitmaskul, S1
Cowell, CT1
Donaghue, K1
Kreutzmann, DJ1
Howard, NJ1
Blades, B1
Silink, M1
Del Monte, P1
Bernasconi, D1
Bertolazzi, L1
Meozzi, M1
Badaracco, B1
Torre, R1
Marugo, M1
De Raeve, L1
De Schepper, J1
Smitz, J1
Paula, FJ1
Gouveia, LM1
Paccola, GM1
Piccinato, CE1
Moreira, AC1
Foss, MC1
Hattori, N1
Ishihara, T1
Moridera, K1
Hino, M1
Ikekubo, K1
Kurahachi, H1
Rhéaume, E1
Sanchez, R1
Simard, J1
Chang, YT2
Wang, J1
Labrie, F2
Warenik-Szymankiewicz, A1
Baron, JJ3
Zmich, C1
Baron, J2
Balducci, R1
Boscherini, B1
Mangiantini, A1
Morellini, M1
Toscano, V1
Young, J1
Couzinet, B1
Pholsena, M1
Nahoul, K1
Schaison, G1
Azziz, R5
Bradley, EL2
Potter, HD2
Boots, LR4
Izumi, H1
Saito, N1
Ichiki, S1
Makino, Y1
Yukitake, K1
Kaneoka, T1
Ghizzoni, L1
Vottero, A1
Cappa, M2
Street, ME2
Bernasconi, S1
Terzolo, M1
Osella, G1
Alì, A1
Borretta, G1
Magro, GP1
Termine, A1
Paccotti, P1
Angeli, A1
Summers, RH1
Herold, DA1
Seely, BL1
Laue, L1
Jones, JV1
Barnes, KM1
Hill, S1
Cutler, GB1
Sakkal-Alkaddour, H1
Zhang, L1
Yang, X1
Kappy, M1
Slover, RS1
Jorgensen, V1
Weber, A1
Camacho-Hübner, C1
Perry, LA2
Brain, CE1
Cotterill, AM1
Savage, MO1
Salinas Vert, I1
Audí Parera, L1
Granada Ybern, ML1
Lucas Martín, A1
Pizarro Lozano, E1
Foz Sala, M1
Sanmartí Sala, A1
Erel, CT1
Senturk, LM1
Oral, E1
Mutlu, H1
Colgar, U1
Seyisoglu, H1
Ertungealp, E1
Moran, C2
Reyna, R2
Huerta, R1
Decanter, C1
Knochenhauer, ES1
Ságodi, L2
Borbás, E1
Réti, G1
Minik, K1
Sólyom, E1
Sánchez, LA1
Ochoa, T1
Maclaren, NK1
Raiti, S1
Bierich, JR1
Gupta, D1
Ferrante, L1
Korth-Schutz, S1
Saenger, P1
Chow, DM2
Keenan, BS1
McNeel, R1
Barrett, GN1
Kirkland, RT1
Clayton, GW1
Faiman, C1
Metcalf, MG1
Gunczler, P1
Hawkins, LA1
Chasalow, FI1
Blethen, SL1
Jaresch, S1
Kornely, E1
Kley, HK1
Schlaghecke, R1
Bates, GW1
French, GM1
Humphries, BB1
Blackhurst, DW1
Akinci, A1
Yordam, N1
Ersoy, F1
Uluşahin, N1
Oğuz, H1
Turner, EI1
Watson, MJ1
White, MC1
del Balzo, P1
Borrelli, P1
Cambiaso, P1
Danielli, E1
Augarten, A1
Pariente, C1
Gazit, E1
Chayen, R1
Goldfarb, H1
Sack, J1
Leite, MV1
Mendonça, BB1
Arnhold, IJ1
Estefan, V1
Nunes, C1
Nicolau, W1
Bloise, W1
Riddick, LM1
Wang, ME1
Senne, AR1
Klimah, PE1
Clark, AT1
Pang, SY1
Rafi, A1
Smith, BR1
Zacur, HA1
Dzenis, IG1
Latypova, NKh1
Kuznetsova, MN1
Siegel, SF1
Finegold, DN1
Lanes, R1
Lee, PA1
Ehrmann, DA1
Rosenfield, RL2
Montalto, J1
Funder, JW1
Yong, AB1
Whorwood, CB1
Connelly, JF1
Hague, WM1
Honour, JW1
Adams, J1
Vecsei, P1
Jacobs, HS1
Ogo, A1
Linder, B1
Feuillan, P1
Chrousos, GP1
Solish, SB1
Goldsmith, MA1
Voutilainen, R1
Vantyghem, MC1
Lemaire, C1
Dufosse, F1
Cohen, I1
Blanstein, J1
Ben-Michael, R1
Lunenfeld, B1
Eshkol, A1
Peterson, RE1
Imperato-McGinley, J1
Gautier, T1
Shackleton, C1
Hammerstein, J1
Boepple, PA1
Mansfield, MJ1
Wierman, ME1
Rudlin, CR1
Bode, HH1
Crigler, JF1
Crawford, JD1
Crowley, WF1
Youlton, R1
Urdl, W1
Schweditsch, MO1
Kowatsch, AW1
Tscherne, G1
Pürstner, P1
Haas, J1
Hauffa, BP1
Menzel, D1
Stolecke, H1
Nakada, T1
Kazama, T1
Koike, H1
Yoshikawa, M1
Ishikawa, S1
Katayama, T1
Dumić, M1
Brkljacić, L1
Mardesić, D1
Plavsić, V1
Lukenda, M1
Kastelan, A1
McKenna, TJ1
Cunningham, SK1
Loughlin, T1
Benjamin, F1
Deutsch, S1
Saperstein, H1
Seltzer, VL1
Sólyom, J1
Gács, G1
Keszei, K1
Láng, K1
Orley, J1
Petheö, I1
Wolthers, BG1
Volmer, M1
van Seters, AP1
Cara, JF1
Moshang, T1
Bongiovanni, AM1
Marx, BS1
Orlova, VG1
Rivera, R1
Dorfman, RI1
Forchielli, E1
Rivarola, MA1
Saez, JM1
Conly, PW1
Sandberg, DH1
Cleveland, WW1
Kenny, FM1
Hashida, Y1
Askari, HA1
Sieber, WH1
Fetterman, GH1
Vadász, E1
Debreczeni, M1
Nagy, T1
Göbel, P4
Osborn, RH1
Yannone, ME1
Bradbury, JT1
Vaitukaitis, JL1
Melby, JC1
Cyran, J1
Goldman, AS2
Dallera, L1
Tassoni, P1
Cicognani, A1
Miano, A1
Schindler, H1
Garmendia, F1
Nicolis, GL1
Gabrilove, JL1
Blunck, W1
Gleispach, H1
Berger, H1
Glatzl, J1
Rössler, H1
Loriaux, DL1
Ruder, HJ1
Lipsett, MB1
Sanghvi, A1
Wight, C1
Serenko, A1
Balachandran, R1
Zachmann, M1
Vollmin, JA1
Murset, G1
Curtius, HC1
Prader, A1
Takahara, J1
Hashimoto, K1
Ofuji, T1
Horký, K1
Kuchel, O1
Gregorová, I1
Stárka, L1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Novel Therapeutic Modality for Congenital Adrenal Hyperplasia[NCT00529841]7 participants (Actual)Interventional2007-01-31Completed
A Mechanistic Examination of Continuous Cycle Oral Contractive Administration in Binge Eating[NCT04278755]Phase 28 participants (Actual)Interventional2020-09-24Terminated (stopped due to Halted prematurely due to COVID-19-related enrollment challenges.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Pre-intervention to Intervention Endpoint in Behavioral Inhibition Subscale Score

The Behavioral Inhibition/Behavioral Activation questionnaire will be used to assess behavioural inhibition (BI). The minimum score on the BI subscale is 7, maximum 28. Greater scores indicate greater BI. Change is defined as the average change in BI from pre-intervention to intervention. (NCT04278755)
Timeframe: Pre-intervention (week 1) to intervention endpoint (week 12)

Interventionscore on a scale (Mean)
Continuous OC1.43

Change From Pre-intervention to Intervention Endpoint in Binge Eating Sum Score

"Binge eating will be measured using the 8-item binge eating subscale of the Eating Pathology Symptoms Inventory (EPSI), which measures features of binge eating (e.g., consumption of large quantities of food, mindless eating) on a 5-point Likert scale from never to very often. The EPSI scale is designed to assess behavior over the past 28 days. Items are summed for a scale score ranging from 0-32. Higher scores indicate more frequent experiences with binge eating behavior. Change is defined as the average change in the binge eating scale score from pre-intervention to intervention." (NCT04278755)
Timeframe: Pre-intervention (week 1) to intervention endpoint (week 12)

Interventionscore on a scale (Mean)
Continuous OC-6.60

Change From Pre-intervention to Intervention Endpoint in Delay Discounting Parameter k

The Monetary Choice Questionnaire will be used to measure delay discounting. Participants will be asked to make a series of hypothetical choices between small, sooner (impulsive) vs. larger, later (self controlled) hypothetical monetary outcomes. k is a hyperbolic function with larger k values indicating more valuation of a larger delayed reward and smaller values indicating preference for more immediate, smaller rewards (more impulsivity). k can range from 0 to .25 with scores of .25 indicating complete valuation of the immediate reward and 0 indicating complete valuation of the larger, delayed reward. Change is defined as the average change in k from pre-intervention to intervention. (NCT04278755)
Timeframe: Pre-intervention (week 1) to intervention endpoint (week 12)

Interventionk value (Mean)
Continuous OC.01

Change From Pre-intervention to Intervention Endpoint in Nucleus Accumbens Signal Intensity in Response to Reward During the Monetary Incentive Delay Task (MIDT)

"Nucleus Accumbens (NAcc) reactivity to reward during the Monetary Incentive Delay (MIDT) task compared pre and post treatment. During MIDT task, participants respond to win trials by pressing a button on a button box in the MRI as quickly as possible when they see a target. Reactivity is measured by examining participant's change in blood-oxygen-level dependent (BOLD) (i.e., measurement of oxygen level that is carried to neurons by red blood cells since areas of the brain that are thought to be more active or involved in certain tasks require more oxygen) in response to a stimulus of interest (win trials) versus non-stimulus (non-win trials). Percent signal change in BOLD activation between monetary reward versus non-reward is the outcome of interest. Percent signal change is then compared pre- and post-treatment." (NCT04278755)
Timeframe: Pre-intervention (week 1) to intervention endpoint (week 12)

Interventionpercentage signal change (Mean)
Continuous OC.0423

Change From Pre-intervention to Intervention Endpoint in Prefrontal Cortex Signal Intensity in Response to Reward During the Monetary Incentive Delay Task (MIDT)

"Prefrontal cortex reactivity to reward during the Monetary Incentive Delay (MIDT) task compared pre and post treatment. During MIDT task, participants respond to win trials by pressing a button on a button box in the MRI as quickly as possible when they see a target. Reactivity is measured by examining participant's change in blood-oxygen-level dependent (BOLD) (i.e., measurement of oxygen level that is carried to neurons by red blood cells since areas of the brain that are thought to be more active or involved in certain tasks require more oxygen) in response to a stimulus of interest (win trials) versus non-stimulus (non-win trials). Percent signal change in BOLD activation between monetary reward versus non-reward is the outcome of interest. Percent signal change is then compared pre- and post-treatment." (NCT04278755)
Timeframe: Pre-intervention (week 1) to intervention endpoint (week 12)

Interventionpercentage signal change (Mean)
Continuous OC.01

Change From Pre-intervention to Intervention Endpoint in Self-reported Reward Sensitivity Subscale Score

Sensitivity to Punishment/Sensitivity to Reward Questionnaire will be used to measure reward sensitivity. The reward sensitivity subscale will be used, which is rated on a true/false scale with scores ranging 0-24. Higher scores indicate more sensitivity to reward. Change is defined as the average change in reward sensitivity from pre-intervention to intervention. (NCT04278755)
Timeframe: Pre-intervention (week 1) to intervention endpoint (week 12)

Interventionscore on a scale (Mean)
Continuous OC1.60

Change From Pre-intervention to Intervention Endpoint in Weekly Average Binge-eating Frequency

Binge eating frequency is based on a weekly diary of self-reported binge eating frequency. Participants were asked how many times during the past week they had a binge eating episode. Scores can range from 0 to infinity as frequency is self-reported as the number of binge eating episodes in the previous week. Higher scores indicate more episodes of binge eating. Change is defined as the average change in self-reported binge eating frequency from pre-intervention to intervention. (NCT04278755)
Timeframe: Pre-intervention (week 1) to intervention endpoint (week 12)

Interventionepisodes/week (Mean)
Continuous OC-0.43

Change From Pre-intervention to Intervention Endpoint in Dorsal Striatum Signal Intensity in Response to Reward During the Monetary Incentive Delay Task (MIDT)

"Dorsal striatum reactivity (defined as caudate signal intensity and putamen signal intensity) to reward during the Monetary Incentive Delay (MIDT) task compared pre and post treatment. During MIDT task, participants respond to win trials by pressing a button on a button box in the MRI as quickly as possible when they see a target. Reactivity is measured by examining participant's change in blood-oxygen-level dependent (BOLD) (i.e., measurement of oxygen level that is carried to neurons by red blood cells since areas of the brain that are thought to be more active or involved in certain tasks require more oxygen) in response to a stimulus of interest (win trials) versus non-stimulus (non-win trials). Percent signal change in BOLD activation between monetary reward versus non-reward is the outcome of interest. Percent signal change is then compared pre- and post-treatment." (NCT04278755)
Timeframe: Pre-intervention (week 1) to intervention endpoint (week 12)

Interventionpercentage signal change (Mean)
CaudatePutamen
Continuous OC-.012.02

Reviews

17 reviews available for dehydroepiandrosterone and Congenital Adrenal Hyperplasia

ArticleYear
Adrenal steroidogenesis and congenital adrenal hyperplasia.
    Endocrinology and metabolism clinics of North America, 2015, Volume: 44, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocortical Adenoma; Aldosterone; Andr

2015
46,XX DSD: the masculinised female.
    Best practice & research. Clinical endocrinology & metabolism, 2010, Volume: 24, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult; An

2010
[The alternative androgen synthesis pathway in humans].
    Klinische Padiatrie, 2013, Volume: 225, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenal Hyperplasia, Con

2013
Androgen biosynthesis from cholesterol to DHEA.
    Molecular and cellular endocrinology, 2002, Dec-30, Volume: 198, Issue:1-2

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Androgens; Animals; Cholesterol; Cholesterol Side-C

2002
Disorders of androgen synthesis--from cholesterol to dehydroepiandrosterone.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2005, Volume: 14 Suppl 1

    Topics: Adrenal Cortex; Adrenal Hyperplasia, Congenital; Androgens; Cholesterol; Cholesterol Side-Chain Clea

2005
[DHEA, DHEA-S].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 8

    Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Biomarkers; Cushing

2005
Steroids in saliva for assessing endocrine function.
    Endocrine reviews, 1982,Fall, Volume: 3, Issue:4

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Age Factors; Breast Neoplasms; Child; Circadian

1982
Hirsutism.
    Archives of dermatology, 1983, Volume: 119, Issue:4

    Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Androgen Antagonists; And

1983
[Common and uncommon forms of female sexual precocity and their biological diagnosis].
    Annales de pediatrie, 1984, Volume: 31, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital;

1984
Hypertension of childhood with suppressed renin.
    Endocrine reviews, 1980,Fall, Volume: 1, Issue:4

    Topics: 18-Hydroxydesoxycorticosterone; 20-alpha-Dihydroprogesterone; Adolescent; Adrenal Cortex; Adrenal Hy

1980
Hirsutism.
    Monographs on endocrinology, 1981, Volume: 19

    Topics: 17-Ketosteroids; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adrenal Gland Neoplasms; Adrenal Hyperplasia

1981
Early steps in androgen biosynthesis: from cholesterol to DHEA.
    Bailliere's clinical endocrinology and metabolism, 1998, Volume: 12, Issue:1

    Topics: Adrenal Hyperplasia, Congenital; Cholesterol; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone

1998
Use of a potent, long acting agonist of gonadotropin-releasing hormone in the treatment of precocious puberty.
    Endocrine reviews, 1986, Volume: 7, Issue:1

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Bone Development; Child; Child, Preschool; Dehydroe

1986
The adrenal cortex and virilization.
    Clinics in endocrinology and metabolism, 1985, Volume: 14, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyper

1985
Inhibition of 3 -hydroxy- 5 -steroid dehydrogenase.
    Gynecologic investigation, 1971, Volume: 2, Issue:1

    Topics: Adrenal Hyperplasia, Congenital; Androstenes; Animals; Antibodies; Cell Differentiation; Dehydroepia

1971
[Some diagnostic and therapeutic aspects of adrenal disorders in childhood (author's transl)].
    Monatsschrift fur Kinderheilkunde, 1973, Volume: 121, Issue:10

    Topics: Addison Disease; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; A

1973
Relationship of androgens to female hirsutism and infertility.
    The Journal of reproductive medicine, 1973, Volume: 11, Issue:3

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Androstenedione; Androstenols; Dehydroepiandrostero

1973

Trials

4 trials available for dehydroepiandrosterone and Congenital Adrenal Hyperplasia

ArticleYear
Colonic mucosal potential differences in the management of 21-hydroxylase deficiency.
    Archives of internal medicine, 1980, Volume: 140, Issue:12

    Topics: Action Potentials; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Androstenedione; Clinical Tr

1980
Usefulness of an ACTH test in the diagnosis of nonclassical 21-hydroxylase deficiency among children presenting with premature pubarche.
    Hormone research, 1995, Volume: 44, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Age of O

1995
A preliminary study of flutamide, testolactone, and reduced hydrocortisone dose in the treatment of congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:10

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Bone Dev

1996
Effect of aminoglutethimide on urinary steroid excretion in patients with congenital adrenal hyperplasia due to incomplete 21-hydroxylase deficiency.
    Metabolism: clinical and experimental, 1972, Volume: 21, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenal Hy

1972

Other Studies

124 other studies available for dehydroepiandrosterone and Congenital Adrenal Hyperplasia

ArticleYear
RNA-Seq reveals ACTH-induced steroid hormone pathway participating in goat adrenal gland response to castration.
    Scientific reports, 2023, 08-28, Volume: 13, Issue:1

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Androgens; Animals; De

2023
New insights into steroidogenesis in normo- and hyperandrogenic polycystic ovary syndrome patients.
    Arquivos brasileiros de endocrinologia e metabologia, 2013, Volume: 57, Issue:6

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult; Case-Control S

2013
The effect of simvastatin treatment on plasma steroid levels in females with non-classic congenital adrenal hyperplasia.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2013, Volume: 121, Issue:10

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adult; Cholesterol; Dehydroepiandrost

2013
The effect of metformin on androgen production in diabetic women with non-classic congenital adrenal hyperplasia.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2014, Volume: 122, Issue:10

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adult; Androgens; Blood Glucose; Dehy

2014
Hormonal circadian rhythms in patients with congenital adrenal hyperplasia: identifying optimal monitoring times and novel disease biomarkers.
    European journal of endocrinology, 2015, Volume: 173, Issue:6

    Topics: 17-alpha-Hydroxyprogesterone; 5-alpha-Dihydroprogesterone; Adrenal Hyperplasia, Congenital; Adrenoco

2015
An improved micro-method for the measurement of steroid profiles by APPI-LC-MS/MS and its use in assessing diurnal effects on steroid concentrations and optimizing the diagnosis and treatment of adrenal insufficiency and CAH.
    The Journal of steroid biochemistry and molecular biology, 2016, Volume: 162

    Topics: Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Androgens; Androsterone; Chromatography, Liq

2016
Non-Virilizing Congenital Adrenal Hyperplasia in a Female Patient with a Novel HSD3B2 Mutation.
    Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation, 2016, Volume: 10, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Amino Acid Sequence; Dehydroepiandros

2016
Gonadal function, first cases of pregnancy, and child delivery in a woman with lipoid congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:4

    Topics: Adrenal Hyperplasia, Congenital; Androgens; Dehydroepiandrosterone; Estradiol; Female; Fetal Death;

2009
Clinical characteristics of Taiwanese children with congenital adrenal hyperplasia caused by 21-hydroxylase deficiency in the pre-screening era.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2010, Volume: 109, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Androstenedione; Dehydroepiandrostero

2010
[DHEA, DHEA-S].
    Nihon rinsho. Japanese journal of clinical medicine, 2010, Volume: 68 Suppl 7

    Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Cushing Syndrome; Dehydroepiandrosterone;

2010
Clinical, biochemical, and molecular characterization of macronodular adrenocortical hyperplasia of the zona reticularis: a new syndrome.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:2

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adult; Blotting, Western; Dehydroepi

2011
Androgens concentrations and second-to fourth-digit ratio (2D:4D) in girls with congenital adrenal hyperplasia (21-hydroxylase deficiency).
    Neuro endocrinology letters, 2012, Volume: 33, Issue:8

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Androgens; Androstenedion

2012
Cortisol, dehydroepiandrosterone sulfate, and androstenedione levels in patients with polymyalgia rheumatica during twelve months of glucocorticoid therapy.
    Annals of the New York Academy of Sciences, 2002, Volume: 966

    Topics: Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aged; Aging; Androsten

2002
[Urinary elimination of 17-ketosteroids and dehydroisoandrosterone in patients with various endocrine diseases (Addison's disease, Cushing's disease, Cushing's syndrome, precocious puberty caused by congenital adrenal hyperplasia, acromegaly)].
    Il Progresso medico, 1955, Jun-30, Volume: 11, Issue:12

    Topics: 17-Ketosteroids; Acromegaly; Addison Disease; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperf

1955
ORIGINS OF HIRSUTISM AND VIRILISM.
    Texas state journal of medicine, 1963, Volume: 59

    Topics: Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Cushing Syndrome; Dehydroepiandrosterone; D

1963
PLASMA ANDROGENS IN WOMEN. II. PATIENTS WITH POLYCYSTIC OVARIES AND HIRSUTISM.
    Acta endocrinologica, 1964, Volume: 45

    Topics: Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Androgens; Androsterone; Blood Chemical Ana

1964
EFFECTS OF SUBSTRATES AND COFACTORS ON STEROID SYNTHESIS IN HYPERPLASTIC ADRENALS.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adrenal Hyperplasia, Congenital; Carbon Isotope

1964
[ADRENOGENITAL SYNDROME CAUSED BY CONGENITAL HYPERPLASIA OF THE ADRENAL CORTEX: PATHOGENETIC IMPORTANCE OF TESTOSTERONE].
    Folia endocrinologica, 1964, Volume: 17

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex; Adrenal Gland Diseases; Adre

1964
A VIRILIZING ADRENAL TUMOR IN A PREPUBERTAL BOY.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: 17-Ketosteroids; Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Cong

1964
DETERMINATION OF URINARY TESTOSTERONE BY CHROMATOGRAPHY AND COLORIMETRY: FINDINGS IN NORMAL SUBJECTS AND IN PATIENTS WITH ENDOCRINE DISEASES.
    The Journal of clinical endocrinology and metabolism, 1965, Volume: 25

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Androg

1965
Premature pubarche as an indicator of how body weight influences the onset of adrenarche.
    European journal of pediatrics, 2004, Volume: 163, Issue:2

    Topics: Adrenal Hyperplasia, Congenital; Birth Weight; Body Weight; Child; Child, Preschool; Dehydroepiandro

2004
Cognitive outcome in adult women affected by congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
    Hormone research, 2006, Volume: 65, Issue:3

    Topics: Adrenal Hyperplasia, Congenital; Adult; Aged; Androgens; Androstenedione; Cognition; Dehydroepiandro

2006
Prevalence of nonclassic adrenal hyperplasia (NCAH) in hyperandrogenic women.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2008, Volume: 24, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Acne Vulgaris; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Ho

2008
Disproportionate suppression of dehydroepiandrosterone sulfate (DHEAS) in treated patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
    Pediatric research, 1983, Volume: 17, Issue:2

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Age Factors; Child; Dehydroepiandrosterone; Dehydroepia

1983
Investigative strategy of hyperandrogenism in women.
    Hormone research, 1983, Volume: 18, Issue:1-3

    Topics: Adrenal Hyperplasia, Congenital; Androgens; Cushing Syndrome; Dehydroepiandrosterone; Female; Gonado

1983
Plasma levels of androgens and 17 alpha-OH-progesterone as an index of the adequacy of treatment in congenital adrenal hyperplasia.
    Hormone research, 1983, Volume: 18, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Androgens; Androstenedion

1983
Virilizing congenital adrenal hyperplasia with normal dehydroepiandrosterone sulfate.
    American journal of obstetrics and gynecology, 1983, Dec-15, Volume: 147, Issue:8

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Aldehyde-Lyases; Child; Dehydroepiand

1983
Metabolism and concentration of androgenic steroids in abdominal skin of hirsute women with androgenital syndrome.
    Acta medica Hungarica, 1984, Volume: 41, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Abdominal Muscles; Adolescent; Adrenal Hyperplasia, Cong

1984
[Hirsutism secondary to congenital adrenal hyperplasia caused by a 21-hydroxylase deficiency of late onset. A clinical case].
    Revista chilena de obstetricia y ginecologia, 1984, Volume: 49, Issue:5

    Topics: 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Dehydroepiandrosterone; Female; Hirsut

1984
Genetic and hormonal characterization of cryptic 21-hydroxylase deficiency.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 53, Issue:6

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Androstenedione; Ch

1981
A comparison of three glucocorticoid suppressive regimes in adults with congenital adrenal hyperplasia.
    Clinical endocrinology, 1982, Volume: 17, Issue:6

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormo

1982
Acth function in women with the polycystic ovarian syndrome.
    Clinical endocrinology, 1983, Volume: 19, Issue:2

    Topics: Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; And

1983
Deficit of 21 beta-hydroxylase. Clinico-functional parameters.
    Clinical and experimental obstetrics & gynecology, 1983, Volume: 10, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocor

1983
Hormonal and clinical responses to prednisone treatment in adolescents with congenital adrenal hyperplasia.
    Hormone research, 1980, Volume: 12, Issue:4

    Topics: 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Adult; Child; Dehydroepiandrosterone;

1980
Amniotic fluid concentrations of delta 5 and delta 4 steroids in fetuses with congenital adrenal hyperplasia due to 21 hydroxylase deficiency and in anencephalic fetuses.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Hyperplasia, Congenital; Amniotic Fluid; Androstenedione; Anen

1980
Cryptic 21-hydroxylase deficiency in families of patients with classical congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:6

    Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Hyperplasia, Congenital; Androstenedione; Child; C

1980
Pitfalls in the etiological diagnosis of congenital adrenal hyperplasia in the early neonatal period.
    Hormone research, 1982, Volume: 16, Issue:1

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Hyperplasia, Congenital; Androstenedione; Dehydroepiandrost

1982
Blunted adrenarche in patients with classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
    Endocrine research, 1995, Volume: 21, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adult; An

1995
Adrenarche does not occur in treated patients with congenital adrenal hyperplasia resulting from 21-hydroxylase deficiency.
    Clinical endocrinology, 1995, Volume: 42, Issue:5

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenocorticotropic H

1995
'Exaggerated adrenarche' in children presenting with premature adrenarche.
    Clinical endocrinology, 1995, Volume: 42, Issue:3

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Diseases; Adrenal Cortex

1995
Increased 17 alpha-hydroxyprogesterone response to ACTH in silent adrenal adenoma: cause or effect?
    Clinical endocrinology, 1995, Volume: 42, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adenoma; Adrenal Cortex Function Tests; Adrenal Gland Neoplasms; Adren

1995
Prepubertal acne: a cutaneous marker of androgen excess?
    Journal of the American Academy of Dermatology, 1995, Volume: 32, Issue:2 Pt 1

    Topics: 17-alpha-Hydroxyprogesterone; Acne Vulgaris; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Ho

1995
Androgen-related effects on peripheral glucose metabolism in women with congenital adrenal hyperplasia.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1994, Volume: 26, Issue:11

    Topics: Adrenal Hyperplasia, Congenital; Adult; Androgens; Androstenedione; Blood Glucose; Dehydroepiandrost

1994
A case of late-onset congenital adrenal hyperplasia due to partial 3 beta-hydroxysteroid dehydrogenase deficiency.
    Endocrine journal, 1993, Volume: 40, Issue:1

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult

1993
Molecular basis of congenital adrenal hyperplasia in two siblings with classical nonsalt-losing 3 beta-hydroxysteroid dehydrogenase deficiency.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 79, Issue:4

    Topics: 3-Hydroxysteroid Dehydrogenases; Adolescent; Adrenal Hyperplasia, Congenital; Base Sequence; Dehydro

1994
[Diagnosis and treatment of congenital adrenal hyperplasia in women].
    Ginekologia polska, 1994, Volume: 65, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adult; Dehydroepiandros

1994
Isolated precocious pubarche: an approach.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 79, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adrenal

1994
Plasma 3 beta-hydroxy-delta 5-steroids in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 78, Issue:2

    Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone; Dehydro

1994
[Differential diagnosis of hirsutism in girls between 15-19 years old].
    Ginekologia polska, 1993, Volume: 64, Issue:5

    Topics: 17-Ketosteroids; Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult; Dehydroepiandro

1993
3 beta-hydroxysteroid dehydrogenase deficiency in hyperandrogenism.
    American journal of obstetrics and gynecology, 1993, Volume: 168, Issue:3 Pt 1

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adrenal

1993
Prenatal diagnosis of congenital lipoid adrenal hyperplasia.
    Obstetrics and gynecology, 1993, Volume: 81, Issue:5 ( Pt 2)

    Topics: Adrenal Hyperplasia, Congenital; Adult; Amniotic Fluid; Dehydroepiandrosterone; Dehydroepiandrostero

1993
Pituitary-ovarian responses to leuprolide acetate testing in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congeni

1996
Different patterns of steroid secretion in patients with adrenal incidentaloma.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adul

1996
Hormonal and genetic analysis of a patient with congenital adrenal hyperplasia.
    Clinical chemistry, 1996, Volume: 42, Issue:9

    Topics: 17-alpha-Hydroxyprogesterone; Acne Vulgaris; Adrenal Hyperplasia, Congenital; Adult; Androstenedione

1996
Studies of 3 beta-hydroxysteroid dehydrogenase genes in infants and children manifesting premature pubarche and increased adrenocorticotropin-stimulated delta 5-steroid levels.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:11

    Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenal Hyperplasia, Congenital; Adre

1996
Treatment-induced hypoandrogenism in childhood and puberty in females with virilizing (21-hydroxylase deficiency) congenital adrenal hyperplasia.
    The Journal of endocrinology, 1996, Volume: 150 Suppl

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Child; Dehydroepiandrosterone; Female; Glucocorticoids;

1996
Girls with virilisation in childhood: a diagnostic protocol for investigation.
    Journal of clinical pathology, 1997, Volume: 50, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Androgens; Child; Child, Preschool; Clini

1997
[Defects of adrenal steroidogenesis in patients with hirsutism].
    Medicina clinica, 1998, Feb-14, Volume: 110, Issue:5

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Cortex Hormones; Adr

1998
Results of the ACTH stimulation test in hirsute women.
    The Journal of reproductive medicine, 1999, Volume: 44, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Function Tests; Adrenal Hyperplasia, Congenital; Adreno

1999
Prevalence of 3beta-hydroxysteroid dehydrogenase-deficient nonclassic adrenal hyperplasia in hyperandrogenic women with adrenal androgen excess.
    American journal of obstetrics and gynecology, 1999, Volume: 181, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adolescent; Adrenal Hyperplasia, Cong

1999
Adrenocortical hyperresponsivity to adrenocorticotropic hormone: a mechanism favoring the normal production of cortisol in 21-hydroxylase-deficient nonclassic adrenal hyperplasia.
    Fertility and sterility, 2000, Volume: 74, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenocorticotropic H

2000
[Precocious puberty caused by a testicular Leydig cell tumor].
    Orvosi hetilap, 2001, Jan-28, Volume: 142, Issue:4

    Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Child, Preschool; Dehydroepiandrostero

2001
Adrenal progestogen and androgen production in 21-hydroxylase-deficient nonclassic adrenal hyperplasia is partially independent of adrenocorticotropic hormone stimulation.
    Fertility and sterility, 2002, Volume: 77, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic H

2002
Gynecomastia with congenital virilizing adrenal hyperplasia (11-beta-hydroxylase deficiency).
    The Journal of pediatrics, 1975, Volume: 86, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Function Tests; Adrenal Hyperplasia, Cong

1975
[Prenatal diagnosis of the congenital adrenogenital syndrome].
    Monatsschrift fur Kinderheilkunde, 1975, Volume: 123, Issue:5

    Topics: Adrenal Hyperplasia, Congenital; Dehydroepiandrosterone; Estriol; Female; Humans; Hydroxyprogesteron

1975
[Complex biochemical aspects in virilizing adrenal gland syndromes].
    Minerva pediatrica, 1976, Jun-23, Volume: 28, Issue:22

    Topics: Adrenal Hyperplasia, Congenital; Androsterone; Dehydroepiandrosterone; Etiocholanolone; Female; Huma

1976
Serum androgens as a continuing index of adequacy of treatment of congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:3

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Androgens; Androsten

1978
Plasma androgens in congenital adrenal hyperplasia: androstenedione concentration as an index of adrenal androgen suppression.
    The Journal of laboratory and clinical medicine, 1979, Volume: 94, Issue:5

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congeni

1979
Serum androgen concentrations in neonates and young infants with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
    Clinical endocrinology, 1979, Volume: 11, Issue:6

    Topics: Adrenal Hyperplasia, Congenital; Age Factors; Androgens; Androstenedione; Dehydroepiandrosterone; Fe

1979
Dehydroepiandrosterone--sulphate in urine.
    Clinical biochemistry, 1978, Volume: 11, Issue:2

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocorticotropic

1978
"Acquired" adrenal hyperplasia with 21-hydroxylase deficiency is not the same genetic disorders as congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 48, Issue:2

    Topics: Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Adrenocor

1979
The role of adrenocorticotropin testing in evaluating girls with premature adrenarche and hirsutism/oligomenorrhea.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 74, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Acne Vulgaris; Adolescent; Adrenal Cortex; Adrenal Cortex Diseases; Ad

1992
Adrenal incidentaloma and patients with homozygous or heterozygous congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 74, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocortic

1992
Outcome of corticotropin stimulation testing in women with androgen excess and ovulatory dysfunction.
    American journal of obstetrics and gynecology, 1992, Volume: 167, Issue:2

    Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Androgens; Dehydroepiandrosterone; Deh

1992
The incidence of non-classical 21-hydroxylase deficiency in hirsute adolescent girls.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1992, Volume: 6, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormo

1992
Investigation of adrenal function in women with oligomenorrhoea and hirsutism (clinical PCOS) from the north-east of England using an adrenal stimulation test.
    Clinical endocrinology, 1992, Volume: 36, Issue:4

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex Function Tests; Adrenal Glands; Adrenal Hyperplasia,

1992
Adrenal steroidogenic defects in children with precocious pubarche.
    Hormone research, 1992, Volume: 37, Issue:4-5

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenal Glands;

1992
Ambiguous genitalia due to partial activity of cytochromes P450c17 and P450c21.
    The Journal of steroid biochemistry and molecular biology, 1992, Volume: 41, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Androstenedione; Chorionic Gonadotrop

1992
Identification of nonclassical 21-hydroxylase deficiency in girls with precocious pubarche.
    Journal of endocrinological investigation, 1991, Volume: 14, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Adrenocorticot

1991
[Endocrine and ultrasound examination of hirsutism].
    Zentralblatt fur Gynakologie, 1991, Volume: 113, Issue:9

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adult; Amenorrhea; Dehy

1991
3 alpha-Androstanediol glucuronide in premature and normal pubarche.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:1

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Andro

1991
On the origin of the elevated 17-hydroxyprogesterone levels after adrenal stimulation in hyperandrogenism.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 70, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adult; Androgens; And

1990
[Clinical variants of virile form of congenital adrenocortical dysfunction].
    Akusherstvo i ginekologiia, 1990, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormo

1990
ACTH stimulation tests and plasma dehydroepiandrosterone sulfate levels in women with hirsutism.
    The New England journal of medicine, 1990, Sep-27, Volume: 323, Issue:13

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congeni

1990
Hirsutism--beyond the steroidogenic block.
    The New England journal of medicine, 1990, Sep-27, Volume: 323, Issue:13

    Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Dehydroepiandrosterone; Dehydroepiandr

1990
Serum levels of 5-androstene-3 beta,17 beta-diol sulphate, 5 alpha-androstane-3 alpha, 17beta-diol sulphate and glucuronide, in late onset 21-hydroxylase deficiency.
    The Journal of steroid biochemistry and molecular biology, 1990, Nov-30, Volume: 37, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; A

1990
Steroid responses to ACTH in women with polycystic ovaries.
    Clinical endocrinology, 1989, Volume: 30, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adult;

1989
[Clinical significance of serum dehydroepiandrosterone and dehydroepiandrosterone sulfate analysis in endocrine tests of the adrenal cortex].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 48 Suppl

    Topics: Adrenal Hyperplasia, Congenital; Age Factors; Aged; Aged, 80 and over; Circadian Rhythm; Cushing Syn

1989
Alternate day prednisone therapy in congenital adrenal hyperplasia: adrenal androgen suppression and normal growth.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 69, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic H

1989
Molecular characterization of a Leydig cell tumor presenting as congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 69, Issue:6

    Topics: 17-alpha-Hydroxyprogesterone; 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocorticotropic

1989
Screening heterozygotes for 21-hydroxylase deficiency among hirsute women: lack of utility of the adrenocorticotropin hormone test.
    Fertility and sterility, 1988, Volume: 50, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormo

1988
Adrenal response to adrenocorticotropin stimulation in unexplained infertile women.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1988, Volume: 27, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; D

1988
Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases. A new variant of congenital adrenal hyperplasia.
    The New England journal of medicine, 1985, Nov-07, Volume: 313, Issue:19

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone

1985
[Current status of gynecologic hormone therapy. Hyperandrogen disorders].
    Archives of gynecology, 1985, Volume: 238, Issue:1-4

    Topics: Adrenal Hyperplasia, Congenital; Androgen Antagonists; Androgens; Cyproterone; Cyproterone Acetate;

1985
[Congenital adrenal hyperplasia: 3 clinical forms in one family].
    Revista medica de Chile, 1985, Volume: 113, Issue:12

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Child; Dehydroepiandrosterone; Female

1985
[Value of laboratory parameters in androgenization in the female with special reference to the "free androgen index"].
    Geburtshilfe und Frauenheilkunde, 1986, Volume: 46, Issue:10

    Topics: Adrenal Hyperplasia, Congenital; Adult; Alopecia; Amenorrhea; Androgens; Dehydroepiandrosterone; Fem

1986
Age-related changes in adrenal size during the first year of life in normal newborns, infants and patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency: comparison of ultrasound and hormonal parameters.
    European journal of pediatrics, 1988, Volume: 148, Issue:1

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Age Factors; Dehydroepiandrosterone; Dehydroepiandr

1988
Primary aldosteronism treated by trilostane (3 beta-hydroxysteroid dehydrogenase inhibitor).
    Urology, 1985, Volume: 25, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adreno

1985
'Cryptic' form of congenital adrenal hyperplasia due to 21-hydroxylase deficiency in the Yugoslav population.
    Acta endocrinologica, 1985, Volume: 109, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; A

1985
Prevalence of and markers for the attenuated form of congenital adrenal hyperplasia and hyperprolactinemia masquerading as polycystic ovarian disease.
    Fertility and sterility, 1986, Volume: 46, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Dehydroe

1986
Detection of late-onset adrenal hyperplasia in girls with peripubertal virilization.
    Acta endocrinologica, 1987, Volume: 115, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormo

1987
Detection of 3 beta-hydroxysteroid-dehydrogenase deficiency by urinary steroid profiling: solvolysis of urinary samples should be a necessary prerequisite.
    Clinica chimica acta; international journal of clinical chemistry, 1985, Feb-15, Volume: 145, Issue:3

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Hyperplasia, Congenital; Adult; Chromatography, Gas; Dehydr

1985
Elevated 17-hydroxyprogesterone and testosterone in a newborn with 3-beta-hydroxysteroid dehydrogenase deficiency.
    The New England journal of medicine, 1985, Sep-05, Volume: 313, Issue:10

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 20-Hydroxysteroid Dehydrogenases; Adrena

1985
[Use of the Fortherby method for determination of dehydroepiandrosterone in urine in the obstetric clinic].
    Laboratornoe delo, 1969, Volume: 6

    Topics: 17-Ketosteroids; Abortion, Habitual; Adrenal Hyperplasia, Congenital; Dehydroepiandrosterone; Female

1969
A modified method for the analysis of urinary 17-ketosteroids, pregnanediol and pregnanetriol by gas liquid chromatography in normal subjects and subjects with various endocrine disorders.
    Acta endocrinologica, 1967, Volume: 54, Issue:1

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Androsterone; Chromatography, Gas; Cushing Syndrom

1967
Studies of androgens in patients with congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:5

    Topics: Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult; Androsterone; Carbon Isotopes; C

1967
Steroid metabolism in premature pubarche and virilizing adrenal hyperplasia.
    The Journal of pediatrics, 1967, Volume: 71, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Androgens;

1967
Virilizing tumors of the adrenal cortex.
    American journal of diseases of children (1960), 1968, Volume: 115, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acne Vulgaris; Adenoma; Adrenal Gland Neoplasms; Adrenal

1968
[On the differential diagnosis of hirsutism].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1968, Apr-01, Volume: 43, Issue:7

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adult; Chiari-Frommel Syndrome; Chromatography; De

1968
[Adrenal hirsutism (3-beta-hydroxysteroid dehydrogenase deficiency). Studies using chromatographic separation of the urinary 17-ketosteroid fraction. 3. On the differential diagnosis of adrenal hirsutism (M. Cushing, congenital adrenogenital syndrome)].
    Endokrinologie, 1968, Volume: 52, Issue:5

    Topics: 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adre

1968
Androgen studies in virilism secondary to an adrenal adenoma and to congenital adrenal hyperplasia.
    Obstetrics and gynecology, 1969, Volume: 33, Issue:5

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Hy

1969
Menstrual disorders associated with adrenal dysfunction.
    Clinical obstetrics and gynecology, 1969, Volume: 12, Issue:3

    Topics: 17-Ketosteroids; Addison Disease; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands;

1969
[Gas chromatography determination of urinary pregnanediol and -triol and its significance for the differentiation of adrenal hirsutism in women].
    Endokrinologie, 1969, Volume: 54, Issue:5

    Topics: 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Adult; C

1969
Virilization of the external genitalia of the female rat fetus by dehydroepiandrosterone.
    Endocrinology, 1970, Volume: 87, Issue:2

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Animals; Dehydroepiandrosterone; Female; Fetus; Mal

1970
[Various aspects of steroidogenesis in congenital adrenogenital syndrome with or without salt loss (determination of the urinary excretion of aldosterone, androsterone, etiocholanolone, dehydroisoandrosterone, 17-hydroxy-11-desoxycorticosterone, pregnaned
    Minerva pediatrica, 1969, May-26, Volume: 21, Issue:21

    Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Androgens; Androsterone; Child; Child, Preschool; Dehy

1969
[Suprarenal virilism].
    Munchener medizinische Wochenschrift (1950), 1970, Oct-16, Volume: 112, Issue:42

    Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Dehydroep

1970
The determination of urinary pregnanetriol and the neutral 17-ketosteroids by gas-liquid chromatography.
    Steroids, 1971, Volume: 18, Issue:2

    Topics: 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adre

1971
[Congenital adrenal hyperplasia; 21-hydroxylase-deficiency combined with 17-desmolase-deficiency (author's transl)].
    Padiatrie und Padologie, 1974, Volume: 9, Issue:3

    Topics: Adrenal Hyperplasia, Congenital; Androsterone; Chemical Phenomena; Chemistry; Dehydroepiandrosterone

1974
Plasma steroids in congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1974, Volume: 39, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Androst

1974
Gas-liquid chromatography of underivatized steroids: simultaneous determination of urinary 17-ketosteroids, pregnanediol, pregnanetriol, and pregnanetriolone.
    Clinica chimica acta; international journal of clinical chemistry, 1974, Oct-15, Volume: 56, Issue:1

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Androsterone; Chromatography, Gas; Computers; Dehy

1974
[Adrenal hirsutism (3beta-hydroxysteroid dehydrogenase deficiency). Studies using a chromatographic separation of the 17-ketosteroid fraction in the urine. 1. Dehydroepiandrosterone-forming adrenocortical adenoma].
    Endokrinologie, 1967, Volume: 52, Issue:1

    Topics: 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocorticotro

1967
[Adrenal hirsutism (3-beta-hydroxysteroid dehydrogenase deficiency). Studies using a chromatographic separation of the urinary 17-ketosteroid fraction. 2. Dehydroepiandrosterone-forming adrenal hyperplasia and constitutional hirsutism].
    Endokrinologie, 1967, Volume: 52, Issue:3

    Topics: 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; An

1967
Unusual type of congenital adrenal hyperplasia probably due to deficiency of 3-beta-hydroxysteroid dehydrogenase. Case report of a surviving girl and steroid studies.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:6

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Adrenocorticotropic

1970
[Gas liquid chromatography analysis of urinary neutral steroid fractions in normal persons and patients with various diseases].
    Nihon Naibunpi Gakkai zasshi, 1970, Jun-20, Volume: 46, Issue:3

    Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormon

1970