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dehydroepiandrosterone and Complications of Diabetes Mellitus

dehydroepiandrosterone has been researched along with Complications of Diabetes Mellitus in 12 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
"In 1994 the Massachusetts Male Aging Study described an inverse correlation of the serum levels of dehydroepiandrosterone sulfate (DHEAS) and the incidence of erectile dysfunction (ED)."9.09Dehydroepiandrosterone in the treatment of erectile dysfunction in patients with different organic etiologies. ( Marberger, M; Märk, I; Pycha, A; Reiter, WJ; Schatzl, G; Zeiner, A, 2001)
"In 1994 the Massachusetts Male Aging Study described an inverse correlation of the serum levels of dehydroepiandrosterone sulfate (DHEAS) and the incidence of erectile dysfunction (ED)."5.09Dehydroepiandrosterone in the treatment of erectile dysfunction in patients with different organic etiologies. ( Marberger, M; Märk, I; Pycha, A; Reiter, WJ; Schatzl, G; Zeiner, A, 2001)
" Since chronic hyperglycemia is central to diabetic complications, and poorly differentiated cells are oxidatively more vulnerable, we currently investigated the effect of glycemic status on MG-induced apoptosis in naïve (nPC12) cells focusing on glutathione-to-glutathione disulfide (GSH/GSSG) redox signaling."3.73Hyperglycemia potentiates carbonyl stress-induced apoptosis in naïve PC-12 cells: relationship to cellular redox and activator protease factor-1 expression. ( Aw, TY; Okayama, N; Okouchi, M, 2005)
"Aldose reductase catalyzes the NADPH-linked reduction of hexoses to their respective sugar-alcohols, which are involved in the pathogenesis of "sugar-cataracts"."3.68Effects of G-6-PD deficiency, experimentally induced or genetically transmitted, on the sorbitol pathway activity. In vitro and in vivo studies. ( Alvarez, A; Chávez, M; Chávez-Anaya, E; Medina, C; Medina, MD; Mendoza, R; Ramírez, MG; Sáenz, G; Vaca, G; Vargas, M, 1992)
" New preparations are being developed to better mimic normal physiological cortisol levels with convenient, once-daily dosing which may improve treatment outcomes."2.49Therapy of endocrine disease: Perspectives on the management of adrenal insufficiency: clinical insights from across Europe. ( Grossman, A; Johannsson, G; Quinkler, M; Zelissen, P, 2013)
"Dehydroepiandrosterone was positively associated with IFG but not with diabetes."1.35Association of endogenous sex hormones with diabetes and impaired fasting glucose in men: multi-ethnic study of atherosclerosis. ( Colangelo, LA; Cushman, M; Dobs, AS; Gapstur, SM; Golden, SH; Kopp, P; Liu, K; Ouyang, P; Szklo, M; Vaidya, D, 2009)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19906 (50.00)18.7374
1990's1 (8.33)18.2507
2000's4 (33.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grossman, A1
Johannsson, G1
Quinkler, M1
Zelissen, P1
Colangelo, LA1
Ouyang, P1
Liu, K1
Kopp, P1
Golden, SH1
Dobs, AS1
Szklo, M1
Vaidya, D1
Cushman, M1
Gapstur, SM1
Okazaki, R1
Shibata, M1
Hayashi, T1
Tanaka, H1
Okouchi, M1
Okayama, N1
Aw, TY1
Andò, S1
Rubens, R1
Rottiers, R1
Gibson, M1
Schiff, I1
Tulchinsky, D1
Ryan, KJ1
Reiter, WJ1
Schatzl, G1
Märk, I1
Zeiner, A1
Pycha, A1
Marberger, M1
Szpunar, WE1
Blair, AJ1
McCann, DS1
Vaca, G1
Ramírez, MG1
Vargas, M1
Mendoza, R1
Chávez-Anaya, E1
Medina, MD1
Alvarez, A1
Medina, C1
Sáenz, G1
Chávez, M1
de Moor, P1
Heyns, W1
Steeno, O1
Faerman, I1
Vilar, O1
Rivarola, MA1
Rosner, JM1
Jadzinsky, MN1
Fox, D1
Lloret, AP1
Bernstein-Hahn, L1
Saraceni, D1
Holzmann, H1
Hoede, N1

Reviews

3 reviews available for dehydroepiandrosterone and Complications of Diabetes Mellitus

ArticleYear
Therapy of endocrine disease: Perspectives on the management of adrenal insufficiency: clinical insights from across Europe.
    European journal of endocrinology, 2013, Volume: 169, Issue:6

    Topics: Addison Disease; Adrenal Insufficiency; Cardiovascular Diseases; Circadian Rhythm; Dehydroepiandrost

2013
[Endocrine disorders in diabetes mellitus].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 8

    Topics: Animals; Bone and Bones; Bone Density; Calcium; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfa

2002
[Current views on the psoriasis problem].
    Hippokrates, 1972, Volume: 43, Issue:1

    Topics: Amyloidosis; Arthritis; Celiac Disease; Cholesterol; Dehydroepiandrosterone; Diabetes Complications;

1972

Trials

1 trial available for dehydroepiandrosterone and Complications of Diabetes Mellitus

ArticleYear
Dehydroepiandrosterone in the treatment of erectile dysfunction in patients with different organic etiologies.
    Urological research, 2001, Volume: 29, Issue:4

    Topics: Adult; Aged; Dehydroepiandrosterone; Diabetes Complications; Erectile Dysfunction; Humans; Hypertens

2001

Other Studies

8 other studies available for dehydroepiandrosterone and Complications of Diabetes Mellitus

ArticleYear
Association of endogenous sex hormones with diabetes and impaired fasting glucose in men: multi-ethnic study of atherosclerosis.
    Diabetes care, 2009, Volume: 32, Issue:6

    Topics: Aged; Aged, 80 and over; Atherosclerosis; Body Mass Index; Cohort Studies; Dehydroepiandrosterone; D

2009
Hyperglycemia potentiates carbonyl stress-induced apoptosis in naïve PC-12 cells: relationship to cellular redox and activator protease factor-1 expression.
    Current neurovascular research, 2005, Volume: 2, Issue:5

    Topics: Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; Brain; Cell Respiration; Dehydroepiandro

2005
Androgen plasma levels in male diabetics.
    Journal of endocrinological investigation, 1984, Volume: 7, Issue:1

    Topics: Adult; Aging; Androgens; Dehydroepiandrosterone; Diabetes Complications; Diabetes Mellitus; Erectile

1984
Characterization of hyperandrogenism with insulin-resistant diabetes type A.
    Fertility and sterility, 1980, Volume: 33, Issue:5

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Androgens; Androstenedione; Cortodoxone; Dehydroepia

1980
Plasma androgen concentrations in diabetic women.
    Diabetes, 1977, Volume: 26, Issue:12

    Topics: Adult; Age Factors; Androgens; Androstenedione; Dehydroepiandrosterone; Diabetes Complications; Diab

1977
Effects of G-6-PD deficiency, experimentally induced or genetically transmitted, on the sorbitol pathway activity. In vitro and in vivo studies.
    Archives of medical research, 1992,Spring, Volume: 23, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Aldehyde Reductase; Animals; Black People

1992
Clinical and biochemical features associated with extreme CBC-values; possible significance of these associations.
    Annales d'endocrinologie, 1968, Volume: 29

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Androsterone; Blood Protein

1968
Impotence and diabetes. Studies of androgenic function in diabetic impotent males.
    Diabetes, 1972, Volume: 21, Issue:1

    Topics: 17-Ketosteroids; Adult; Androgens; Androsterone; Chorionic Gonadotropin; Dehydroepiandrosterone; Dia

1972