Page last updated: 2024-11-07

dehydroepiandrosterone and Colitis

dehydroepiandrosterone has been researched along with Colitis in 7 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"Dehydroepiandrosterone (DHEA) is a popular dietary supplement that has anti-inflammatory, anti-oxidant and immune-regulating role; meanwhile, it also can effective in the protection of inflammation diseases such as inflammatory bowel disease (IBD), but the underlying mechanisms remain elusive."5.62Dehydroepiandrosterone alleviates intestinal inflammatory damage via GPR30-mediated Nrf2 activation and NLRP3 inflammasome inhibition in colitis mice. ( Cao, J; Li, L; Lu, M; Ma, H; Yan, W, 2021)
"7α-Hydroxy dehydroepiandrosterone (7α-OH-prasterone, 7α-OH-DHEA) is a key steroid intermediate in the synthesis of valuable pharmaceuticals widely used in the treatment of autoimmune illness, rheumatoid arthritis, colitis, and other severe diseases."4.31Selective Microbial Conversion of DHEA into 7α-OH-DHEA. ( Donova, MV; Kollerov, VV; Shutov, AA, 2023)
"Dehydroepiandrosterone (DHEA) is a hormone that plays an important role in the modulation of inflammatory responses."1.43Dehydroepiandrosterone (DHEA) restrains intestinal inflammation by rendering leukocytes hyporesponsive and balancing colitogenic inflammatory responses. ( Alves, VB; Basso, PJ; Cardoso, CR; Chica, JE; Nardini, V; Silva, A, 2016)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Kollerov, VV1
Shutov, AA1
Donova, MV1
Cao, J2
Zhang, H1
Yang, Z1
Zhao, J1
Ma, H2
Lu, M1
Yan, W1
Li, L1
Alves, VB1
Basso, PJ1
Nardini, V1
Silva, A1
Chica, JE1
Cardoso, CR1
Auci, DL1
Reading, CL1
Frincke, JM1
PORTELLA, A1
Pélissier, MA1
Muller, C1
Hill, M1
Morfin, R1

Reviews

1 review available for dehydroepiandrosterone and Colitis

ArticleYear
7-Hydroxy androstene steroids and a novel synthetic analogue with reduced side effects as a potential agent to treat autoimmune diseases.
    Autoimmunity reviews, 2009, Volume: 8, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Clinical Trials as Topic; Colitis; Dehyd

2009

Other Studies

6 other studies available for dehydroepiandrosterone and Colitis

ArticleYear
Selective Microbial Conversion of DHEA into 7α-OH-DHEA.
    Methods in molecular biology (Clifton, N.J.), 2023, Volume: 2704

    Topics: Arthritis, Rheumatoid; Colitis; Dehydroepiandrosterone; Ethanol; Humans; Hydroxylation

2023
Effect of dehydroepiandrosterone on the immune response and gut microbiota in dextran sulfate sodium-induced colitis mice.
    Molecular immunology, 2020, Volume: 118

    Topics: Animals; Anti-Inflammatory Agents; Colitis; Colon; Cytokines; Dehydroepiandrosterone; Dextran Sulfat

2020
Dehydroepiandrosterone alleviates intestinal inflammatory damage via GPR30-mediated Nrf2 activation and NLRP3 inflammasome inhibition in colitis mice.
    Free radical biology & medicine, 2021, 08-20, Volume: 172

    Topics: Animals; Colitis; Dehydroepiandrosterone; Inflammasomes; Mice; NF-E2-Related Factor 2; NLR Family, P

2021
Dehydroepiandrosterone (DHEA) restrains intestinal inflammation by rendering leukocytes hyporesponsive and balancing colitogenic inflammatory responses.
    Immunobiology, 2016, Volume: 221, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Cell Proliferation; Colitis; Cytokines; Dehydroepiandrosterone; D

2016
[Use of dehydroisoandrosterone in the treatment of colitis].
    Rassegna internazionale di clinica e terapia, 1957, Jan-31, Volume: 37, Issue:2

    Topics: Androgens; Biological Assay; Colitis; Dehydroepiandrosterone

1957
Protection against dextran sodium sulfate-induced colitis by dehydroepiandrosterone and 7alpha-hydroxy-dehydroepiandrosterone in the rat.
    Steroids, 2006, Volume: 71, Issue:3

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adjuvants,

2006