dehydroepiandrosterone has been researched along with Colitis Gravis in 5 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pouchitis is a common complication after proctocolectomy for ulcerative colitis and still a therapeutical challenge." | 5.32 | Treatment of pouchitis with dehydroepiandrosterone (DHEA) - a case report. ( Andus, T; Bregenzer, N; Klebl, FH; Rogler, G; Schölmerich, J; Straub, RH, 2003) |
| "Treatment with dehydroepiandrosterone was effective in randomized controlled trials in patients with systemic lupus erythematosus." | 2.71 | Patients with refractory Crohn's disease or ulcerative colitis respond to dehydroepiandrosterone: a pilot study. ( Andus, T; Bregenzer, N; Klebl, F; Rogler, G; Schölmerich, J; Straub, RH, 2003) |
| "Sixty-six patients hospitalized for ulcerative colitis were treated in a prospective, double-blind, clinical trial." | 2.65 | Corticotropin versus hydrocortisone in the intravenous treatment of ulcerative colitis. A prospective, randomized, double-blind clinical trial. ( Goldberg, JD; Janowitz, HD; Meyers, S; Sachar, DB, 1983) |
| " HE3286 is orally bioavailable and treats established disease in models of ulcerative colitis, collagen-induced arthritis, and collagen antibody-induced arthritis, reducing clinical signs of disease and proinflammatory signals, including IL-6 and matrix metallopeptidase 3." | 1.35 | HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease. ( Ahlem, C; Auci, D; Frincke, J; Mangano, K; Nicoletti, F; Reading, C; Stickney, D, 2009) |
| "Pouchitis is a common complication after proctocolectomy for ulcerative colitis and still a therapeutical challenge." | 1.32 | Treatment of pouchitis with dehydroepiandrosterone (DHEA) - a case report. ( Andus, T; Bregenzer, N; Klebl, FH; Rogler, G; Schölmerich, J; Straub, RH, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahlem, C | 1 |
| Auci, D | 1 |
| Mangano, K | 1 |
| Reading, C | 1 |
| Frincke, J | 1 |
| Stickney, D | 1 |
| Nicoletti, F | 1 |
| Andus, T | 2 |
| Klebl, F | 1 |
| Rogler, G | 2 |
| Bregenzer, N | 2 |
| Schölmerich, J | 2 |
| Straub, RH | 2 |
| Klebl, FH | 1 |
| Meyers, S | 1 |
| Sachar, DB | 1 |
| Goldberg, JD | 1 |
| Janowitz, HD | 1 |
| Osathanondh, R | 1 |
| Fencl, MD | 1 |
| Schiff, I | 1 |
| Himmel, M | 1 |
| Tulchinsky, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blind, Multi-Center, Dose Response, Efficacy and Safety Evaluation of Inflabloc Cap in the Treatment of Patients With Moderately Active Crohn's Disease[NCT00106314] | Phase 2 | 75 participants | Interventional | 2005-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for dehydroepiandrosterone and Colitis Gravis
| Article | Year |
|---|---|
Patients with refractory Crohn's disease or ulcerative colitis respond to dehydroepiandrosterone: a pilot study.
Topics: Adjuvants, Immunologic; Adult; Chronic Disease; Colitis, Ulcerative; Crohn Disease; Dehydroepiandros | 2003 |
Corticotropin versus hydrocortisone in the intravenous treatment of ulcerative colitis. A prospective, randomized, double-blind clinical trial.
Topics: Adrenocorticotropic Hormone; Adult; Clinical Trials as Topic; Colitis, Ulcerative; Dehydroepiandrost | 1983 |
3 other studies available for dehydroepiandrosterone and Colitis Gravis
| Article | Year |
|---|---|
HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease.
Topics: Administration, Oral; Androstenols; Animals; Autoimmune Diseases; Clinical Trials as Topic; Colitis, | 2009 |
Treatment of pouchitis with dehydroepiandrosterone (DHEA) - a case report.
Topics: Adjuvants, Immunologic; Adult; Colitis, Ulcerative; Dehydroepiandrosterone; Endoscopy; Female; Follo | 2003 |
Reduced urinary and serum total estriol levels in pregnancies after colectomy.
Topics: Adrenal Glands; Adult; Colectomy; Colitis, Ulcerative; Crohn Disease; Dehydroepiandrosterone; Entero | 1979 |