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dehydroepiandrosterone and Cognition Disorders

dehydroepiandrosterone has been researched along with Cognition Disorders in 34 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"To assess the relationships between circulating levels of proinflammatory cytokines and adrenocortical hormones and leptin early after stroke."7.70Cortisol axis abnormalities early after stroke--relationships to cytokines and leptin. ( Ahrén, B; Carlström, K; Johansson, A; Näsman, B; Olsson, T, 2000)
"Data regarding cognitive function, symptom severity, daily doses, side effects of antipsychotic agents and blood levels of DHEA, DHEAS, androstenedione and cortisol were collected among 55 schizophrenia patients in a double-blind, randomized, placebo-controlled, crossover trial with DHEA at three intervals: upon study entry, after 6weeks of DHEA administration (200mg/d), and after 6weeks of a placebo period."5.14Neurocognitive deficits in schizophrenia are associated with alterations in blood levels of neurosteroids: a multiple regression analysis of findings from a double-blind, randomized, placebo-controlled, crossover trial with DHEA. ( Ritsner, MS; Strous, RD, 2010)
"The relationship between the content of serum hormones (thyrotrophic hormone, thyroxin, dehydroepiandrosterone (DHEA), DHEA sulfate, prolactin) and cognitive impairment at the acute phase of ischemic stroke in the 1(st), 7(th) and 21(st) day was investigated."3.79[Hormonal markers of cognitive impairment in patients with the first stroke]. ( Gudkova, VV; Kispaeva, TT; Kol'tsova, EA; Ostrovtsev, IV, 2013)
"To assess the relationships between circulating levels of proinflammatory cytokines and adrenocortical hormones and leptin early after stroke."3.70Cortisol axis abnormalities early after stroke--relationships to cytokines and leptin. ( Ahrén, B; Carlström, K; Johansson, A; Näsman, B; Olsson, T, 2000)
"All randomized placebo-controlled trials enrolling people aged over 50 without dementia and to whom DHEA/S in any dosage was administered for more than one day were considered for inclusion in the review."2.43Dehydroepiandrosterone (DHEA) supplementation for cognitive function in healthy elderly people. ( Grimley Evans, J; Huppert, F; Malouf, R; van Niekerk, JK, 2006)
" We don't know the possible negative consequences of long-term administration of DHEA\\DHEAS on cardiovascular disease and hormone-dependent cancers."2.42[DHEA and aging]. ( Pitti-Ferrandi, H, 2003)
"Dehydroepiandrosterone (DHEA) is a steroid secreted by the adrenal cortex, with a characteristic, age-related, pattern of secretion."2.40DHEA deficiency syndrome: a new term for old age? ( Hinson, JP; Raven, PW, 1999)
"Chronic fatigue syndrome is defined by the Atlanta Centers for Disease Control (Atlanta, GA, USA) as debilitating fatigue lasting for longer than 6 months."1.31Serum concentrations of some metals and steroids in patients with chronic fatigue syndrome with reference to neurological and cognitive abnormalities. ( Carstens, ME; Emsley, RA; Hugo, F; Hurly, PR; Kiss, T; Mansvelt, E; Potocnik, FC; Taljaard, JJ; Theodorou, P; van Rensburg, SJ; van Zijl, P, 2001)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.88)18.2507
2000's19 (55.88)29.6817
2010's12 (35.29)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Sultana, F1
Davis, SR1
Islam, RM1
Kispaeva, TT1
Ostrovtsev, IV1
Gudkova, VV1
Kol'tsova, EA1
Maggio, M2
De Vita, F1
Fisichella, A1
Colizzi, E1
Provenzano, S1
Lauretani, F1
Luci, M1
Ceresini, G2
Dall'Aglio, E1
Caffarra, P1
Valenti, G2
Ceda, GP1
Pluchino, N1
Drakopoulos, P1
Bianchi-Demicheli, F1
Wenger, JM1
Petignat, P1
Genazzani, AR1
Corrêa, MS1
Vedovelli, K1
Giacobbo, BL1
de Souza, CE1
Ferrari, P1
de Lima Argimon, II1
Walz, JC1
Kapczinski, F1
Bromberg, E1
Pukhal'skiĭ, AL1
Shmarina, GV1
Aleshkin, VA1
Eden, JA1
Ritsner, MS1
Strous, RD1
Yamada, S1
Akishita, M1
Fukai, S1
Ogawa, S1
Yamaguchi, K1
Matsuyama, J1
Kozaki, K1
Toba, K1
Ouchi, Y1
Rammouz, G1
Lecanu, L1
Aisen, P1
Papadopoulos, V1
Moriguchi, S1
Yamamoto, Y1
Ikuno, T1
Fukunaga, K1
Johansson, P1
Johansson, JO1
Labrie, F1
Mattsson, N1
Hansson, O1
Blennow, K1
Zetterberg, H1
Wallin, A1
Ohlsson, C1
Svensson, J1
Sorwell, KG1
Garten, J1
Renner, L1
Weiss, A1
Garyfallou, VT1
Kohama, SG1
Neuringer, M1
Urbanski, HF1
Wolkowitz, OM1
Epel, ES1
Reus, VI1
Ferrari, E2
Mirani, M1
Barili, L2
Falvo, F1
Solerte, SB1
Cravello, L2
Pini, L1
Magri, F2
Arlt, W1
Pitti-Ferrandi, H1
Fonda, SJ1
Bertrand, R1
O'Donnell, A1
Longcope, C1
McKinlay, JB1
Avital, A1
Ram, E1
Maayan, R1
Weizman, A1
Richter-Levin, G1
Sarra, S1
Cinchetti, W1
Salmoiraghi, F1
Micale, G1
Grimley Evans, J1
Malouf, R1
Huppert, F1
van Niekerk, JK4
Denti, L1
Saccò, M1
Bossoni, S1
Giustina, A1
Maugeri, D1
Vigna, GB1
Fellin, R1
Paolisso, G1
Barbagallo, M1
Strollo, F1
Bollanti, L1
Romanelli, F1
Latini, M1
Neri, M1
Bonati, PA1
Pinelli, M1
Borella, P1
Tolve, I1
Nigro, N1
Raven, PW2
Hinson, JP2
Goldman, N1
Glei, DA1
Huppert, FA3
Fuller, SJ1
Tan, RS1
Martins, RN1
Barrett-Connor, E1
Edelstein, SL1
Johansson, A1
Ahrén, B1
Näsman, B1
Carlström, K1
Olsson, T1
Herbert, J1
van Rensburg, SJ1
Potocnik, FC1
Kiss, T1
Hugo, F1
van Zijl, P1
Mansvelt, E1
Carstens, ME1
Theodorou, P1
Hurly, PR1
Emsley, RA1
Taljaard, JJ1
Young, AH1
Gallagher, P1
Porter, RJ1

Reviews

14 reviews available for dehydroepiandrosterone and Cognition Disorders

ArticleYear
Effect of dehydroepiandrosterone therapy on cognitive performance among postmenopausal women: a systematic review of randomized clinical trial data.
    Menopause (New York, N.Y.), 2023, 11-01, Volume: 30, Issue:11

    Topics: Aged; Cognition; Cognition Disorders; Cross-Over Studies; Dehydroepiandrosterone; Female; Humans; Po

2023
DHEA and cognitive function in the elderly.
    The Journal of steroid biochemistry and molecular biology, 2015, Volume: 145

    Topics: Adult; Aged; Aged, 80 and over; Animals; Brain; Cognition; Cognition Disorders; Cross-Sectional Stud

2015
Neurobiology of DHEA and effects on sexuality, mood and cognition.
    The Journal of steroid biochemistry and molecular biology, 2015, Volume: 145

    Topics: Affect; Animals; Anxiety; Brain; Cognition; Cognition Disorders; Dehydroepiandrosterone; Dehydroepia

2015
Stress hormone-related psychopathology: pathophysiological and treatment implications.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2001, Volume: 2, Issue:3

    Topics: Antidepressive Agents; Cognition Disorders; Corticosterone; Cushing Syndrome; Dehydroepiandrosterone

2001
Dehydroepiandrosterone replacement therapy.
    Seminars in reproductive medicine, 2004, Volume: 22, Issue:4

    Topics: Adrenal Insufficiency; Aging; Animals; Autoimmune Diseases; Cognition Disorders; Dehydroepiandroster

2004
[DHEA and aging].
    Psychologie & neuropsychiatrie du vieillissement, 2003, Volume: 1, Issue:2

    Topics: Adjuvants, Immunologic; Aged; Aging; Alzheimer Disease; Cognition Disorders; Dehydroepiandrosterone;

2003
Stress and dementia: the role of the hypothalamicpituitary-adrenal axis.
    Aging clinical and experimental research, 2006, Volume: 18, Issue:2

    Topics: Adult; Aged; Aging; Alzheimer Disease; Case-Control Studies; Circadian Rhythm; Cognition Disorders;

2006
Dehydroepiandrosterone (DHEA) supplementation for cognitive function in healthy elderly people.
    The Cochrane database of systematic reviews, 2006, Oct-18, Issue:4

    Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; Dehydroepiandrosterone; Dehydroepiandroster

2006
Dehydroepiandrosterone (DHEA) and the menopause: an update.
    Menopause international, 2007, Volume: 13, Issue:2

    Topics: Adjuvants, Immunologic; Breast Neoplasms; Cardiovascular Diseases; Cognition Disorders; Dehydroepian

2007
WITHDRAWN: Dehydroepiandrosterone (DHEA) supplementation for cognitive function.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:2

    Topics: Adult; Cognition; Cognition Disorders; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dieta

2007
Androgens in the etiology of Alzheimer's disease in aging men and possible therapeutic interventions.
    Journal of Alzheimer's disease : JAD, 2007, Volume: 12, Issue:2

    Topics: Aged; Aging; Alzheimer Disease; Androgens; Cognition Disorders; Dehydroepiandrosterone; Follicle Sti

2007
DHEA deficiency syndrome: a new term for old age?
    The Journal of endocrinology, 1999, Volume: 163, Issue:1

    Topics: Adolescent; Adrenal Cortex; Adult; Aged; Aged, 80 and over; Aging; Child; Cognition Disorders; Dehyd

1999
Dehydroepiandrosterone (DHEA) supplementation for cognition and well-being.
    The Cochrane database of systematic reviews, 2000, Issue:2

    Topics: Adult; Cognition; Cognition Disorders; Dehydroepiandrosterone; Dementia; Female; Health Status; Huma

2000
Dehydroepiandrosterone (DHEA) supplementation for cognitive function .
    The Cochrane database of systematic reviews, 2001, Issue:2

    Topics: Adult; Cognition; Cognition Disorders; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dieta

2001

Trials

2 trials available for dehydroepiandrosterone and Cognition Disorders

ArticleYear
Neurocognitive deficits in schizophrenia are associated with alterations in blood levels of neurosteroids: a multiple regression analysis of findings from a double-blind, randomized, placebo-controlled, crossover trial with DHEA.
    Journal of psychiatric research, 2010, Volume: 44, Issue:2

    Topics: Adult; Androstenedione; Cognition Disorders; Cross-Over Studies; Dehydroepiandrosterone; Dehydroepia

2010
Effects of dehydroepiandrosterone supplementation on cognitive function and activities of daily living in older women with mild to moderate cognitive impairment.
    Geriatrics & gerontology international, 2010, Volume: 10, Issue:4

    Topics: Activities of Daily Living; Adjuvants, Immunologic; Administration, Oral; Aged; Aged, 80 and over; C

2010

Other Studies

18 other studies available for dehydroepiandrosterone and Cognition Disorders

ArticleYear
[Hormonal markers of cognitive impairment in patients with the first stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2013, Volume: 113, Issue:12 Pt 2

    Topics: Aged; Biomarkers; Cognition Disorders; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Femal

2013
Psychophysiological correlates of cognitive deficits in family caregivers of patients with Alzheimer Disease.
    Neuroscience, 2015, Feb-12, Volume: 286

    Topics: Aged; Alzheimer Disease; Brain-Derived Neurotrophic Factor; Caregivers; Cognition Disorders; Dehydro

2015
[Immune dysfunction and cognitive deficit in stress and physiological aging. Part II: New approaches to cognitive disorder prevention and treatment ].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 2014, Issue:7-8

    Topics: Adaptation, Physiological; Adaptation, Psychological; Adjuvants, Immunologic; Aging; Angiotensin II

2014
DHEA replacement for postmenopausal women: placebo or panacea?
    Climacteric : the journal of the International Menopause Society, 2015, Volume: 18, Issue:4

    Topics: Administration, Intravaginal; Administration, Oral; Aged; Aging; Cognition Disorders; Dehydroepiandr

2015
A lead study on oxidative stress-mediated dehydroepiandrosterone formation in serum: the biochemical basis for a diagnosis of Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2011, Volume: 24 Suppl 2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Case-Control Studies; Cognition Di

2011
Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice.
    Journal of neurochemistry, 2011, Volume: 117, Issue:5

    Topics: Animals; Anisoles; Avoidance Learning; Behavior, Animal; Blotting, Western; CA1 Region, Hippocampal;

2011
Mild dementia is associated with increased adrenal secretion of cortisol and precursor sex steroids in women.
    Clinical endocrinology, 2011, Volume: 75, Issue:3

    Topics: Adrenal Glands; Aged; Aged, 80 and over; Androsterone; Chromatography, Liquid; Cognition Disorders;

2011
Hormone supplementation during aging: how much and when?
    Rejuvenation research, 2012, Volume: 15, Issue:2

    Topics: Aging; Androgens; Animals; Cognition; Cognition Disorders; Dehydroepiandrosterone; Hormones; Macaca

2012
Cognitive and affective disorders in the elderly: a neuroendocrine study.
    Archives of gerontology and geriatrics. Supplement, 2004, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Circadian Rhythm; Cognition Disorders; Comorbidity; Dehydroepiandros

2004
Age, hormones, and cognitive functioning among middle-aged and elderly men: cross-sectional evidence from the Massachusetts Male Aging Study.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2005, Volume: 60, Issue:3

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Androgens; Blood Chemical Analysis; Cognition; Cognitio

2005
Effects of early-life stress on behavior and neurosteroid levels in the rat hypothalamus and entorhinal cortex.
    Brain research bulletin, 2006, Feb-15, Volume: 68, Issue:6

    Topics: Affective Symptoms; Age Factors; Animals; Cognition Disorders; Dehydroepiandrosterone; Dehydroepiand

2006
Consensus Document on substitution therapy with DHEA in the elderly.
    Aging clinical and experimental research, 2006, Volume: 18, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Atherosclerosis; Bone Diseases, Metabolic; Cognition Disorder

2006
Biological, psychological and clinical markers of caregiver's stress in impaired elderly with dementia and age-related disease.
    Archives of gerontology and geriatrics, 2007, Volume: 44 Suppl 1

    Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Caregivers; Cognition Disorders; Cross-Sectional S

2007
Sex differences in the relationship between DHEAS and health.
    Experimental gerontology, 2007, Volume: 42, Issue:10

    Topics: Aged; Aging; Asian People; Biomarkers; Cognition Disorders; Dehydroepiandrosterone; Dehydroepiandros

2007
A prospective study of dehydroepiandrosterone sulfate and cognitive function in an older population: the Rancho Bernardo Study.
    Journal of the American Geriatrics Society, 1994, Volume: 42, Issue:4

    Topics: Age Factors; Aged; California; Cause of Death; Cognition Disorders; Dehydroepiandrosterone; Educatio

1994
Cortisol axis abnormalities early after stroke--relationships to cytokines and leptin.
    Journal of internal medicine, 2000, Volume: 247, Issue:2

    Topics: Adrenocorticotropic Hormone; Aged; Aged, 80 and over; Body Mass Index; Case-Control Studies; Circadi

2000
Serum concentrations of some metals and steroids in patients with chronic fatigue syndrome with reference to neurological and cognitive abnormalities.
    Brain research bulletin, 2001, May-15, Volume: 55, Issue:2

    Topics: Adult; Aluminum; Binding, Competitive; Cholesterol; Cognition Disorders; Copper; Dehydroepiandroster

2001
Elevation of the cortisol-dehydroepiandrosterone ratio in drug-free depressed patients.
    The American journal of psychiatry, 2002, Volume: 159, Issue:7

    Topics: Adolescent; Adult; Biomarkers; Circadian Rhythm; Cognition Disorders; Dehydroepiandrosterone; Depres

2002