dehydroepiandrosterone has been researched along with Cocaine Abuse in 8 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Yohimbine increased ratings of anxiety both before (p < 0." | 5.19 | Yohimbine administration and cue-reactivity in cocaine-dependent individuals. ( Baker, NL; Brady, KT; McRae-Clark, A; Moran-Santa Maria, MM; Ramakrishnan, V, 2014) |
| " DHEA does not seem to decrease cocaine self-administration by increasing the reinforcing properties of the drug, as indicated by a cocaine dose-response determination." | 1.33 | DHEA, a neurosteroid, decreases cocaine self-administration and reinstatement of cocaine-seeking behavior in rats. ( Doron, R; Fridman, L; Gispan-Herman, I; Maayan, R; Weizman, A; Yadid, G, 2006) |
| "Therefore, neuroendocrine control of cocaine addiction may not involve solely glucocorticoids." | 1.32 | Sigma 1 receptor-related neuroactive steroids modulate cocaine-induced reward. ( Bowen, WD; Martin-Fardon, R; Maurice, T; Romieu, P, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (87.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moran-Santa Maria, MM | 1 |
| McRae-Clark, A | 1 |
| Baker, NL | 1 |
| Ramakrishnan, V | 1 |
| Brady, KT | 1 |
| Romieu, P | 2 |
| Martin-Fardon, R | 1 |
| Bowen, WD | 1 |
| Maurice, T | 2 |
| Shoptaw, S | 1 |
| Majewska, MD | 2 |
| Wilkins, J | 1 |
| Twitchell, G | 1 |
| Yang, X | 1 |
| Ling, W | 1 |
| Wilkins, JN | 1 |
| Van Gorp, W | 1 |
| Li, SH | 1 |
| Hinken, C | 1 |
| Plotkin, D | 1 |
| Setoda, D | 1 |
| Harris, DS | 1 |
| Reus, VI | 1 |
| Wolkowitz, OM | 1 |
| Mendelson, JE | 1 |
| Jones, RT | 1 |
| Lucas, M | 1 |
| Maayan, R | 2 |
| Lotan, S | 1 |
| Doron, R | 2 |
| Shabat-Simon, M | 1 |
| Gispan-Herman, I | 2 |
| Weizman, A | 2 |
| Yadid, G | 2 |
| Fridman, L | 1 |
4 trials available for dehydroepiandrosterone and Cocaine Abuse
| Article | Year |
|---|---|
Yohimbine administration and cue-reactivity in cocaine-dependent individuals.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Anxiety; Cocaine-Related Disorders; Craving; Cross-O | 2014 |
Participants receiving dehydroepiandrosterone during treatment for cocaine dependence show high rates of cocaine use in a placebo-controlled pilot study.
Topics: Adolescent; Adult; Aged; Cocaine-Related Disorders; Dehydroepiandrosterone; Female; Humans; Male; Mi | 2004 |
DHEAS and POMS measures identify cocaine dependence treatment outcome.
Topics: Adult; Affect; Cocaine; Cocaine-Related Disorders; Dehydroepiandrosterone; Dehydroepiandrosterone Su | 2005 |
Repeated psychological stress testing in stimulant-dependent patients.
Topics: Affect; Aged; Amphetamine-Related Disorders; Blood Pressure; Central Nervous System Stimulants; Coca | 2005 |
4 other studies available for dehydroepiandrosterone and Cocaine Abuse
| Article | Year |
|---|---|
Sigma 1 receptor-related neuroactive steroids modulate cocaine-induced reward.
Topics: Animals; Behavior, Animal; Cinnamates; Cocaine; Cocaine-Related Disorders; Conditioning, Psychologic | 2003 |
Sigma1 receptor ligands and related neuroactive steroids interfere with the cocaine-induced state of memory.
Topics: Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Cocaine; Cocaine-Related Disord | 2006 |
Dehydroepiandrosterone (DHEA) attenuates cocaine-seeking behavior in the self-administration model in rats.
Topics: Affect; Animals; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Cocaine | 2006 |
DHEA, a neurosteroid, decreases cocaine self-administration and reinstatement of cocaine-seeking behavior in rats.
Topics: Adjuvants, Immunologic; Analysis of Variance; Anesthetics, Local; Animals; Behavior, Addictive; Beha | 2006 |