Page last updated: 2024-11-07

dehydroepiandrosterone and Cirrhosis

dehydroepiandrosterone has been researched along with Cirrhosis in 8 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
" The following study investigates the ovarian hyperfibrosis forming via transforming growth factor-β (TGF-β) signaling pathway in Dehydroepiandrosterone (DHEA)- induced polycystic ovary syndrome (PCOS) rat model."3.88DHEA-induced ovarian hyperfibrosis is mediated by TGF-β signaling pathway. ( Gao, Q; He, X; Liang, Q; Shen, S; Wang, D; Wang, H; Wang, W; Wang, Y; Xia, Y, 2018)
" Dehydroepiandrosterone (DHEA) effectively treats experimental pulmonary hypertension in chronically hypoxic and monocrotaline-injected rats."3.79Dehydroepiandrosterone restores right ventricular structure and function in rats with severe pulmonary arterial hypertension. ( Abe, K; Alzoubi, A; Fagan, KA; McMurtry, IF; O'Neill, KD; Oka, M; Rocic, P; Toba, M, 2013)
"Dehydroepiandrosterone (DHEA) is an abundant steroid and precursor of sex hormones."1.91DHEA and Its Metabolites Reduce the Cytokines Involved in the Inflammatory Response and Fibrosis in Primary Biliary Cholangitis. ( Blatkiewicz, M; Kilańczyk, E; Piotrowska, K; Sielatycka, K, 2023)
"Dehydroepiandrosterone (DHEA) is a naturally occurring adrenal androgen that has antioxidant properties."1.37The effect of DHEA treatment on the oxidative stress and myocardial fibrosis induced by Keshan disease pathogenic factors. ( Chen, X; Fan, Z; Jia, C; Li, M; Li, X; Miao, C; Ren, L; Sun, B, 2011)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Blatkiewicz, M1
Sielatycka, K1
Piotrowska, K1
Kilańczyk, E1
Chen, L1
Li, M2
Shen, M1
Zhu, Y1
Chen, K1
Huang, X1
Zheng, C1
Wang, Q1
Lin, H1
Liao, W1
Bin, J1
Ma, S1
Liao, Y1
Weng, Y1
Zhang, Y1
Wang, D2
Wang, R1
Xiang, Z1
Shen, S3
Wang, H2
Wu, X1
Wen, Y1
Wang, Y3
Wang, W1
Liang, Q1
He, X1
Xia, Y1
Gao, Q2
Alzoubi, A1
Toba, M1
Abe, K1
O'Neill, KD1
Rocic, P1
Fagan, KA1
McMurtry, IF1
Oka, M1
Zhang, X1
Zhang, C1
Xia, Yj1
Yi, L1
Jia, C1
Chen, X1
Li, X1
Miao, C1
Sun, B1
Fan, Z1
Ren, L1
Aragno, M1
Mastrocola, R1
Alloatti, G1
Vercellinatto, I1
Bardini, P1
Geuna, S1
Catalano, MG1
Danni, O1
Boccuzzi, G1

Other Studies

8 other studies available for dehydroepiandrosterone and Cirrhosis

ArticleYear
DHEA and Its Metabolites Reduce the Cytokines Involved in the Inflammatory Response and Fibrosis in Primary Biliary Cholangitis.
    International journal of molecular sciences, 2023, Mar-10, Volume: 24, Issue:6

    Topics: Aged; Cytokines; Dehydroepiandrosterone; Female; Fibrosis; Humans; Interleukin-8; Interleukins; Live

2023
Bioinformatics exploration of potential common therapeutic targets for systemic and pulmonary arterial hypertension-induced myocardial hypertrophy.
    Acta biochimica et biophysica Sinica, 2023, May-25, Volume: 55, Issue:5

    Topics: Animals; Cardiomegaly; Computational Biology; Dehydroepiandrosterone; Fibrosis; Hypertrophy, Left Ve

2023
Exercise-induced irisin improves follicular dysfunction by inhibiting IRE1α-TXNIP/ROS-NLRP3 pathway in PCOS.
    Journal of ovarian research, 2023, Jul-31, Volume: 16, Issue:1

    Topics: Animals; Carrier Proteins; Cell Cycle Proteins; Dehydroepiandrosterone; Endoribonucleases; Female; F

2023
DHEA-induced ovarian hyperfibrosis is mediated by TGF-β signaling pathway.
    Journal of ovarian research, 2018, Jan-10, Volume: 11, Issue:1

    Topics: Animals; Biomarkers; Dehydroepiandrosterone; Disease Models, Animal; Estrous Cycle; Female; Fibrosis

2018
Dehydroepiandrosterone restores right ventricular structure and function in rats with severe pulmonary arterial hypertension.
    American journal of physiology. Heart and circulatory physiology, 2013, Jun-15, Volume: 304, Issue:12

    Topics: Animals; Apoptosis; Blood Pressure; Dehydroepiandrosterone; Fibrosis; Gene Expression; Heart Ventric

2013
Dehydroepiandrosterone induces ovarian and uterine hyperfibrosis in female rats.
    Human reproduction (Oxford, England), 2013, Volume: 28, Issue:11

    Topics: Animals; Dehydroepiandrosterone; Female; Fibrosis; Hypoglycemic Agents; Hypolipidemic Agents; Metfor

2013
The effect of DHEA treatment on the oxidative stress and myocardial fibrosis induced by Keshan disease pathogenic factors.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2011, Volume: 25, Issue:3

    Topics: Animals; Body Weight; Cardiomyopathies; Connective Tissue Growth Factor; Dehydroepiandrosterone; Dis

2011
Oxidative stress triggers cardiac fibrosis in the heart of diabetic rats.
    Endocrinology, 2008, Volume: 149, Issue:1

    Topics: Animals; Connective Tissue Growth Factor; Dehydroepiandrosterone; Diabetes Mellitus, Experimental; D

2008