dehydroepiandrosterone has been researched along with Chronic Pain in 7 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Chronic Pain: Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " If an association was found, we further explored dose-response relationships by the number of pain locations and the degree of pain interference." | 5.62 | Blood Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate as Pathophysiological Correlates of Chronic Pain: Analyses Using a National Sample of Midlife Adults in the United States. ( Chapman, BP; Li, R; Smith, SM, 2021) |
| "Many dysfunctional and chronic pain conditions overlap." | 2.53 | Dysfunctional stress responses in chronic pain. ( Dutheil, F; Picard, P; Woda, A, 2016) |
| " If an association was found, we further explored dose-response relationships by the number of pain locations and the degree of pain interference." | 1.62 | Blood Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate as Pathophysiological Correlates of Chronic Pain: Analyses Using a National Sample of Midlife Adults in the United States. ( Chapman, BP; Li, R; Smith, SM, 2021) |
| "Patients with temporomandibular disorders (TMD) commonly experience myofascial and joint pain, pain-related disability, and other pain conditions including depression." | 1.43 | Association of pain intensity, pain-related disability, and depression with hypothalamus-pituitary-adrenal axis function in female patients with chronic temporomandibular disorders. ( Ahn, RS; Jo, KB; Lee, IG; Lee, SC; Lee, YJ; Park, JY, 2016) |
| " Understandably, physicians might not believe patients who claim that a standard opioid dosage is an ineffective treatment." | 1.42 | Hormone abnormalities in patients with severe and chronic pain who fail standard treatments. ( Tennant, F, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Haack, M | 1 |
| Engert, LC | 1 |
| Besedovsky, L | 1 |
| Goldstein, MR | 1 |
| Devine, JK | 1 |
| Dang, R | 1 |
| Olia, K | 1 |
| Molina, V | 1 |
| Bertisch, SM | 1 |
| Sethna, N | 1 |
| Simpson, N | 1 |
| Li, R | 1 |
| Chapman, BP | 1 |
| Smith, SM | 1 |
| Tennant, F | 1 |
| Jo, KB | 1 |
| Lee, YJ | 1 |
| Lee, IG | 1 |
| Lee, SC | 1 |
| Park, JY | 1 |
| Ahn, RS | 1 |
| Woda, A | 1 |
| Picard, P | 1 |
| Dutheil, F | 1 |
| Rendina, DN | 1 |
| Ryff, CD | 1 |
| Coe, CL | 1 |
| Aloisi, AM | 1 |
| Buonocore, M | 1 |
| Merlo, L | 1 |
| Galandra, C | 1 |
| Sotgiu, A | 1 |
| Bacchella, L | 1 |
| Ungaretti, M | 1 |
| Demartini, L | 1 |
| Bonezzi, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Relationship Between Central Sensitization and Alteration of Circulating Neurosteroid Following Bilateral Total Knee Arthroplasty[NCT03298711] | 69 participants (Actual) | Observational | 2017-11-20 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for dehydroepiandrosterone and Chronic Pain
| Article | Year |
|---|---|
Dysfunctional stress responses in chronic pain.
Topics: Chronic Pain; Cushing Syndrome; Cytokines; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; H | 2016 |
6 other studies available for dehydroepiandrosterone and Chronic Pain
| Article | Year |
|---|---|
Alterations of pain pathways by experimental sleep disturbances in humans: central pain-inhibitory, cyclooxygenase, and endocannabinoid pathways.
Topics: Chronic Disease; Chronic Pain; Cyclooxygenase 2; Dehydroepiandrosterone; Endocannabinoids; Female; H | 2023 |
Blood Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate as Pathophysiological Correlates of Chronic Pain: Analyses Using a National Sample of Midlife Adults in the United States.
Topics: Adult; Aged; Aged, 80 and over; Chronic Pain; Cohort Studies; Cross-Sectional Studies; Dehydroepiand | 2021 |
Hormone abnormalities in patients with severe and chronic pain who fail standard treatments.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Biomarkers; Chronic Pain; Dehydroepiandrosterone; Female; | 2015 |
Association of pain intensity, pain-related disability, and depression with hypothalamus-pituitary-adrenal axis function in female patients with chronic temporomandibular disorders.
Topics: Adult; Chronic Pain; Circadian Rhythm; Comorbidity; Dehydroepiandrosterone; Depression; Depressive D | 2016 |
Precipitous Dehydroepiandrosterone Declines Reflect Decreased Physical Vitality and Function.
Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Chronic Disease; Chronic Pain; Dehydroepiandroste | 2017 |
Chronic pain therapy and hypothalamic-pituitary-adrenal axis impairment.
Topics: Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Analgesics; Case-Control Studies; Chronic Pai | 2011 |