dehydroepiandrosterone has been researched along with Choriocarcinoma in 12 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, cultured human choriocarcinoma JEG-3 cells were used as an experimental model in order to examine the effect of dehydroepiandrosterone sulfate on both de novo and low-density lipoprotein-stimulated progesterone secretion." | 7.67 | The effect of dehydroepiandrosterone sulfate on de novo and low-density lipoprotein-stimulated progesterone secretion by human choriocarcinoma JEG-3 cells. ( Benveniste, R; Ilekis, J; Moise, J; Scommegna, A, 1986) |
| "The estradiol (E2) to estriol (E3) ratio during human pregnancy depends on fetal liver hydroxylation of fetal adrenal dehydroepiandrosterone sulfate (DHEAS) and conversion by the trophoblast of DHEAS and 16 alpha-hydroxy-DHEAS (16 OH-DHEAS) to estrone (E1), estradiol (E2), and estriol (E3), respectively." | 7.67 | Competitive studies with dehydroepiandrosterone sulfate and 16 alpha-hydroxydehydroepiandrosterone sulfate in cultured human choriocarcinoma JEG-3 cells: effect on estrone, 17 beta-estradiol, and estriol secretion. ( Benveniste, R; Ilekis, J; Scommegna, A; Zbella, EA, 1986) |
| " In the present study, cultured human choriocarcinoma JEG-3 cells were used as an experimental model in order to examine the effect of dehydroepiandrosterone sulfate on both de novo and low-density lipoprotein-stimulated progesterone secretion." | 3.67 | The effect of dehydroepiandrosterone sulfate on de novo and low-density lipoprotein-stimulated progesterone secretion by human choriocarcinoma JEG-3 cells. ( Benveniste, R; Ilekis, J; Moise, J; Scommegna, A, 1986) |
| "The estradiol (E2) to estriol (E3) ratio during human pregnancy depends on fetal liver hydroxylation of fetal adrenal dehydroepiandrosterone sulfate (DHEAS) and conversion by the trophoblast of DHEAS and 16 alpha-hydroxy-DHEAS (16 OH-DHEAS) to estrone (E1), estradiol (E2), and estriol (E3), respectively." | 3.67 | Competitive studies with dehydroepiandrosterone sulfate and 16 alpha-hydroxydehydroepiandrosterone sulfate in cultured human choriocarcinoma JEG-3 cells: effect on estrone, 17 beta-estradiol, and estriol secretion. ( Benveniste, R; Ilekis, J; Scommegna, A; Zbella, EA, 1986) |
| "Urinary estradiol production rates, plasma estradiol, and peripheral conversion of dehydroepiandrosterone sulfate (DHEAS) to estradiol were explored in patients whose neoplasms made human chorionic gonadotropin and/or human chorionic gonadotropin beta fragments." | 3.66 | Estrogen production as a tumor marker in patients with gonadotropin-producing neoplasms. ( Berkowitz, R; Drejka, M; Kirschner, MA; Lippman, A; Mayrer, E, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Samson, M | 1 |
| Labrie, F | 1 |
| Luu-The, V | 1 |
| Falany, CN | 1 |
| He, D | 1 |
| Dumas, N | 1 |
| Frost, AR | 1 |
| Falany, JL | 1 |
| Kirschner, MA | 3 |
| Lippman, A | 1 |
| Berkowitz, R | 1 |
| Mayrer, E | 1 |
| Drejka, M | 1 |
| Maeyama, M | 1 |
| Ifuku, M | 1 |
| Nakahara, K | 1 |
| Schut, HA | 1 |
| Townsley, JD | 1 |
| Moise, J | 1 |
| Ilekis, J | 2 |
| Scommegna, A | 2 |
| Benveniste, R | 2 |
| Zbella, EA | 1 |
| Barlow, JJ | 1 |
| Goldstein, DP | 1 |
| Reid, DE | 1 |
| Wider, JA | 1 |
| Ross, GT | 1 |
| MacDonald, PC | 1 |
| Siiteri, PK | 1 |
| Cohen, FB | 1 |
| Jespersen, D | 1 |
| Pattillo, RA | 1 |
| Hussa, RO | 1 |
| Huang, WY | 1 |
| Delfs, E | 1 |
| Mattingly, RF | 1 |
12 other studies available for dehydroepiandrosterone and Choriocarcinoma
| Article | Year |
|---|---|
Specific estradiol biosynthetic pathway in choriocarcinoma (JEG-3) cell line.
Topics: 3-Hydroxysteroid Dehydrogenases; Aromatase; Carbon Radioisotopes; Cell Line, Tumor; Choriocarcinoma; | 2009 |
Human cytosolic sulfotransferase 2B1: isoform expression, tissue specificity and subcellular localization.
Topics: Amino Acid Sequence; Animals; Breast; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cel | 2006 |
Estrogen production as a tumor marker in patients with gonadotropin-producing neoplasms.
Topics: Choriocarcinoma; Chorionic Gonadotropin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Est | 1981 |
Steroidogenesis in cerebral metastatic chorionepithelioma tissue in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Brain Neoplasms; Choriocarcinoma; Dehydroepiandroster | 1975 |
Oestrogen formation from C19 precursors in human choriocarcinoma in culture.
Topics: Algestone; Androgens; Androstenedione; Bucladesine; Cell Line; Cholesterol; Choriocarcinoma; Clone C | 1977 |
The effect of dehydroepiandrosterone sulfate on de novo and low-density lipoprotein-stimulated progesterone secretion by human choriocarcinoma JEG-3 cells.
Topics: Cell Line; Cells, Cultured; Choriocarcinoma; Culture Media; Dehydroepiandrosterone; Dehydroepiandros | 1986 |
Competitive studies with dehydroepiandrosterone sulfate and 16 alpha-hydroxydehydroepiandrosterone sulfate in cultured human choriocarcinoma JEG-3 cells: effect on estrone, 17 beta-estradiol, and estriol secretion.
Topics: Cells, Cultured; Choriocarcinoma; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; | 1986 |
A study of in vitro estrogen biosynthesis and production rates in normal pregnancy, hydatidiform mole and choriocarcinoma.
Topics: Adolescent; Adult; Carbon Isotopes; Choriocarcinoma; Dehydroepiandrosterone; Estradiol; Estriol; Est | 1967 |
Leydig cell function in men with gonadotrophin-producing testicular tumors.
Topics: Adult; Choriocarcinoma; Chorionic Gonadotropin; Chromatography, Gas; Dehydroepiandrosterone; Electro | 1970 |
The in vivo mechanisms of origin of estrogen in subjects with trophoblastic tumors.
Topics: Adolescent; Adult; Carbon Isotopes; Choriocarcinoma; Chromatography; Dehydroepiandrosterone; Estradi | 1966 |
Estrogen production and its origin in men with gonadotropin-producing neoplasms.
Topics: Adult; Aged; Choriocarcinoma; Dehydroepiandrosterone; Estradiol; Estrone; Hormones, Ectopic; Humans; | 1974 |
Estrogen production by trophoblastic tumors in tissue culture.
Topics: 17-Ketosteroids; Androstanes; Cell Line; Choriocarcinoma; Chromatography; Culture Techniques; Dehydr | 1972 |