Page last updated: 2024-11-07

dehydroepiandrosterone and Cholangitis, Sclerosing

dehydroepiandrosterone has been researched along with Cholangitis, Sclerosing in 1 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Cholangitis, Sclerosing: Chronic inflammatory disease of the BILIARY TRACT. It is characterized by fibrosis and hardening of the intrahepatic and extrahepatic biliary ductal systems leading to bile duct strictures, CHOLESTASIS, and eventual BILIARY CIRRHOSIS.

Research Excerpts

ExcerptRelevanceReference
"and aims: Primary sclerosing cholangitis is a Th1 cytokine driven disease with a poor clinical responsiveness to glucocorticoid therapy."1.32Glucocorticoid receptors are downregulated in hepatic T lymphocytes in rats with experimental cholangitis. ( Le, T; Swain, MG; Tjandra, K, 2003)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tjandra, K1
Le, T1
Swain, MG1

Other Studies

1 other study available for dehydroepiandrosterone and Cholangitis, Sclerosing

ArticleYear
Glucocorticoid receptors are downregulated in hepatic T lymphocytes in rats with experimental cholangitis.
    Gut, 2003, Volume: 52, Issue:9

    Topics: 1-Naphthylisothiocyanate; Animals; Cholangitis, Sclerosing; Chronic Disease; Corticosterone; Dehydro

2003