dehydroepiandrosterone has been researched along with Chagas Disease in 16 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dehydroepiandrosterone (DHEA) has long been considered as a precursor for many steroid hormones." | 5.35 | Trypanosoma cruzi: dehydroepiandrosterone (DHEA) and immune response during the chronic phase of the experimental Chagas' disease. ( Brazão, V; Caetano, LC; Caetano, LN; Caldeira, JC; Del Vecchio Filipin, M; do Prado Júnior, JC; Santello, FH; Toldo, MP, 2009) |
| "To analyze the association of circulating dehydroepiandrosterone sulfate (DHEA-S) levels with cardiovascular outcomes in patients with chronic Chagas cardiomyopathy (CCM) diagnosis." | 4.12 | Circulating DHEA-S levels and major cardiovascular outcomes in chronic Chagas cardiomyopathy: A prospective cohort study. ( Bautista-Niño, PK; Echeverría, LE; Eisenga, MF; Gómez-Ochoa, SA; Hunziker, L; Muka, T; Rojas, LZ, 2022) |
| "Chagas' disease is considered the sixth most important neglected tropical disease worldwide." | 1.36 | Immunomodulatory effects of zinc and DHEA on the Th-1 immune response in rats infected with Trypanosoma cruzi. ( Brazão, V; Caetano, LC; Del Vecchio Filipin, M; do Prado, JC; Santello, FH; Toldo, MP, 2010) |
| "Dehydroepiandrosterone is an abundant steroid hormone secreted by the human adrenal cortex and it is considered potent immune-activator." | 1.36 | DHEA and testosterone therapies in Trypanosoma cruzi-infected rats are associated with thymic changes. ( Brazão, V; Caetano, LC; do Prado, JC; Filipin, Mdel V; Santello, FH; Toldo, MP, 2010) |
| "American Trypanosomiasis is caused by the hemoflagellate Trypanosoma cruzi (T." | 1.35 | Steroidogenic capacity of Trypanosoma cruzi trypomastigotes. ( Gómez, Y; Revelli, S; Romano, MC; Vacchina, P; Valdéz, RA, 2008) |
| "Dehydroepiandrosterone (DHEA) has long been considered as a precursor for many steroid hormones." | 1.35 | Trypanosoma cruzi: dehydroepiandrosterone (DHEA) and immune response during the chronic phase of the experimental Chagas' disease. ( Brazão, V; Caetano, LC; Caetano, LN; Caldeira, JC; Del Vecchio Filipin, M; do Prado Júnior, JC; Santello, FH; Toldo, MP, 2009) |
| "Treatment with melatonin, DHEA and the association showed a significant reduction in the number of blood trypomastigotes during the acute phase of infection as compared to untreated animals (P < 0." | 1.35 | Melatonin and dehydroepiandrosterone combination: does this treatment exert a synergistic effect during experimental Trypanosoma cruzi infection? ( Alonso Toldo, MP; de Albuquerque, S; do Prado, JC; Ferreira, DS; Kuehn, CC; Rodrigues Oliveira, LG; Santos, CD, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (43.75) | 29.6817 |
| 2010's | 7 (43.75) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Rojas, LZ | 1 |
| Gómez-Ochoa, SA | 1 |
| Echeverría, LE | 1 |
| Bautista-Niño, PK | 1 |
| Hunziker, L | 1 |
| Eisenga, MF | 1 |
| Muka, T | 1 |
| Bottasso, O | 1 |
| Roggero, E | 1 |
| Del Rey, A | 1 |
| Wildmann, J | 1 |
| Besedovsky, H | 1 |
| Vacchina, P | 1 |
| Valdéz, RA | 1 |
| Gómez, Y | 1 |
| Revelli, S | 2 |
| Romano, MC | 1 |
| Filipin, Mdel V | 4 |
| Brazão, V | 6 |
| Caetano, LC | 5 |
| Santello, FH | 6 |
| Toldo, MP | 9 |
| Caetano, LN | 2 |
| do Prado, JC | 7 |
| Del Vecchio Filipin, M | 2 |
| Caldeira, JC | 2 |
| do Prado Júnior, JC | 3 |
| Kuehn, CC | 2 |
| Rodrigues Oliveira, LG | 1 |
| Santos, CD | 4 |
| Ferreira, DS | 1 |
| Alonso Toldo, MP | 1 |
| de Albuquerque, S | 1 |
| Gupta, S | 1 |
| Cordeiro, AT | 1 |
| Michels, PA | 1 |
| Oliveira, LG | 1 |
| Augusto, MB | 1 |
| Pérez, AR | 1 |
| Bertoya, AA | 1 |
| García, F | 1 |
| dos Santos, CD | 1 |
| Levy, AM | 1 |
| Kawasse, LM | 1 |
| Zucoloto, S | 1 |
1 review available for dehydroepiandrosterone and Chagas Disease
| Article | Year |
|---|---|
Glucocorticoids and sympathetic neurotransmitters modulate the acute immune response to Trypanosoma cruzi.
Topics: Animals; CD8-Positive T-Lymphocytes; Chagas Disease; Cytokines; Dehydroepiandrosterone; Disease Mode | 2019 |
15 other studies available for dehydroepiandrosterone and Chagas Disease
| Article | Year |
|---|---|
Circulating DHEA-S levels and major cardiovascular outcomes in chronic Chagas cardiomyopathy: A prospective cohort study.
Topics: Biomarkers; Cardiomyopathies; Chagas Cardiomyopathy; Chagas Disease; Dehydroepiandrosterone; Female; | 2022 |
The potential implication of decreased DHEA levels in the pathophysiology of chronic Chagas cardiomyopathy.
Topics: Cardiomyopathies; Chagas Cardiomyopathy; Chagas Disease; Dehydroepiandrosterone; Humans | 2022 |
Steroidogenic capacity of Trypanosoma cruzi trypomastigotes.
Topics: Androgens; Androstenedione; Animals; Chagas Disease; Dehydroepiandrosterone; Estrogens; Female; Huma | 2008 |
Trypanosoma cruzi: orchiectomy and dehydroepiandrosterone therapy in infected rats.
Topics: Adjuvants, Immunologic; Animals; Cell Count; Chagas Disease; Dehydroepiandrosterone; Heart; Interfer | 2008 |
Trypanosoma cruzi: dehydroepiandrosterone (DHEA) and immune response during the chronic phase of the experimental Chagas' disease.
Topics: Animals; Ascitic Fluid; Cell Proliferation; Chagas Disease; Chronic Disease; Dehydroepiandrosterone; | 2009 |
Immunomodulatory effects of zinc and DHEA on the Th-1 immune response in rats infected with Trypanosoma cruzi.
Topics: Adjuvants, Immunologic; Animals; Cell Count; Chagas Disease; Cytokines; Dehydroepiandrosterone; Free | 2010 |
Melatonin and dehydroepiandrosterone combination: does this treatment exert a synergistic effect during experimental Trypanosoma cruzi infection?
Topics: Adjuvants, Immunologic; Animals; Antioxidants; Chagas Disease; Dehydroepiandrosterone; Drug Combinat | 2009 |
DHEA and testosterone therapies in Trypanosoma cruzi-infected rats are associated with thymic changes.
Topics: Animals; Antiprotozoal Agents; Chagas Disease; Dehydroepiandrosterone; Interleukin-12; Male; Parasit | 2010 |
Corticosterone evaluation in Wistar rats infected with the Y strain of Trypanosoma cruzi during the chronic phase.
Topics: Adrenal Cortex; Animals; Chagas Disease; Chronic Disease; Corticosterone; Dehydroepiandrosterone; In | 2011 |
Glucose-6-phosphate dehydrogenase is the target for the trypanocidal action of human steroids.
Topics: Androsterone; Cell Line; Chagas Disease; Dehydroepiandrosterone; Dose-Response Relationship, Drug; D | 2011 |
Prior and concomitant dehydroepiandrosterone treatment affects immunologic response of cultured macrophages infected with Trypanosoma cruzi in vitro?
Topics: Animals; Chagas Disease; Dehydroepiandrosterone; Interleukin-12; Macrophages, Peritoneal; Male; Nitr | 2011 |
A high corticosterone/DHEA-s ratio in young rats infected with Trypanosoma cruzi is associated with increased susceptibility.
Topics: Acute Disease; Animals; Chagas Disease; Corticosterone; Cytokines; Dehydroepiandrosterone; Disease S | 2011 |
Trypanosoma cruzi: the effects of dehydroepiandrosterone (DHEA) treatment during experimental infection.
Topics: Adjuvants, Immunologic; Animals; Blood Glucose; Body Weight; Chagas Disease; Dehydroepiandrosterone; | 2005 |
Dehydroepiandrosterone affects Trypanosoma cruzi tissue parasite burdens in rats.
Topics: Animals; Chagas Disease; Dehydroepiandrosterone; Female; Heart; Macrophages, Peritoneal; Male; Rats; | 2007 |
Dehydroepiandrosterone increases resistance to experimental infection by Trypanosoma cruzi.
Topics: Adjuvants, Immunologic; Animals; Chagas Disease; Dehydroepiandrosterone; Female; Interferon-gamma; I | 2008 |