dehydroepiandrosterone has been researched along with Central Hypothyroidism in 22 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Objective The present study was aimed at assessing whether oral dehydroepiandrosterone affects thyroid autoimmunity and hypothalamic-pituitary-thyroid axis activity in men with subclinical hypothyroidism induced by Hashimoto's thyroiditis." | 8.02 | Impact of dehydroepiandrosterone on thyroid autoimmunity and function in men with autoimmune hypothyroidism. ( Krysiak, R; Okopień, B; Szkróbka, W, 2021) |
| " We examined serum concentrations of ADIOL, ADIOLS, DHEA, DHEAS and pregnenolone sulfate (5-pregnen-3beta-ol-20-one sulfate, PREGS) in patients with Graves' thyrotoxicosis (male/female 9/14), hypothyroidism (11/20) and in normal controls (14/29)." | 7.71 | Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism. ( Amino, N; Fukata, S; Izumi, Y; Kobayashi, Y; Kuma, K; Tada, H; Tagawa, N; Takano, T, 2001) |
| "We were interested if the treatment of hypothyroidism would affect the above factors." | 5.31 | Effect of treatment of hypothyroidism on the plasma concentrations of neuroactive steroids and homocysteine. ( Bicíková, M; Hill, M; Putz, Z; Tallová, J; Tomandl, J; Vañuga, A, 2001) |
| " Objective The present study was aimed at assessing whether oral dehydroepiandrosterone affects thyroid autoimmunity and hypothalamic-pituitary-thyroid axis activity in men with subclinical hypothyroidism induced by Hashimoto's thyroiditis." | 4.02 | Impact of dehydroepiandrosterone on thyroid autoimmunity and function in men with autoimmune hypothyroidism. ( Krysiak, R; Okopień, B; Szkróbka, W, 2021) |
| " We examined serum concentrations of ADIOL, ADIOLS, DHEA, DHEAS and pregnenolone sulfate (5-pregnen-3beta-ol-20-one sulfate, PREGS) in patients with Graves' thyrotoxicosis (male/female 9/14), hypothyroidism (11/20) and in normal controls (14/29)." | 3.71 | Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism. ( Amino, N; Fukata, S; Izumi, Y; Kobayashi, Y; Kuma, K; Tada, H; Tagawa, N; Takano, T, 2001) |
| "Plasma dehydroepiandrosterone sulphate (DHEAS), cortisol (F) and prolactin (PRL) were measured in seventeen premenopausal women with primary hypothyroidism and in fifteen normal premenopausal women." | 3.66 | Plasma dehydroepiandrosterone sulphate in hypothyroid premenopausal women. ( Bassi, F; Fiorelli, G; Forti, G; Giannotti, P; Pinchera, A; Pupi, A; Serio, M, 1980) |
| " New preparations are being developed to better mimic normal physiological cortisol levels with convenient, once-daily dosing which may improve treatment outcomes." | 2.49 | Therapy of endocrine disease: Perspectives on the management of adrenal insufficiency: clinical insights from across Europe. ( Grossman, A; Johannsson, G; Quinkler, M; Zelissen, P, 2013) |
| "Hypothyroidism was significantly more common in patients after chemoradiotherapy than in those who received only chemotherapy (χ2=9." | 1.91 | [Endocrine disorders after combined chemoradiotherapy in Hodgkin Lymphoma survivors]. ( Fazullina, ON; Klimontov, VV; Pospelova, TI; Shebunyaeva, YY; Voytko, MS, 2023) |
| "Future studies on primary hypothyroidism should focus on role of lower DHEAS levels in inducing symptoms of fatigue and joint pains." | 1.62 | Dehydroepiandrostenedione sulphate (DHEAS) levels predict high risk of rheumatoid arthritis (RA) in subclinical hypothyroidism. ( Agarwal, M; Ganeshani, M; Jangir, R; Kandel, G; Sankanagoudar, S; Shukla, R; Srivastava, S, 2021) |
| "We were interested if the treatment of hypothyroidism would affect the above factors." | 1.31 | Effect of treatment of hypothyroidism on the plasma concentrations of neuroactive steroids and homocysteine. ( Bicíková, M; Hill, M; Putz, Z; Tallová, J; Tomandl, J; Vañuga, A, 2001) |
| "Dehydroepiandrosterone (DHEA) is a peroxisome proliferating agent when administered in pharmacological dosages, but it has not been shown to function through the peroxisome proliferator-activated receptor in cell-based assays." | 1.29 | Regulation of CYP4A expression in rat by dehydroepiandrosterone and thyroid hormone. ( Geoghegan, TE; Prough, RA; Webb, SJ; Xiao, GH, 1996) |
| "Hypothyroidism is associated with a severe retardation of body growth, which appears more marked in thyroidectomized than in MMI treated rats; no significant variations in testis weight are observed." | 1.28 | Influence of hypothyroidism on in-vitro testicular steroidogenesis in adult rats. ( Andó, S; Beraldi, E; Fugassa, E; Palmero, S; Panno, ML; Prati, M; Salerno, M; Tarantino, G, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (22.73) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 4 (18.18) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Voytko, MS | 1 |
| Klimontov, VV | 1 |
| Pospelova, TI | 1 |
| Shebunyaeva, YY | 1 |
| Fazullina, ON | 1 |
| Krysiak, R | 1 |
| Szkróbka, W | 1 |
| Okopień, B | 1 |
| Shukla, R | 1 |
| Ganeshani, M | 1 |
| Agarwal, M | 1 |
| Jangir, R | 1 |
| Kandel, G | 1 |
| Sankanagoudar, S | 1 |
| Srivastava, S | 1 |
| Aicher, KM | 1 |
| Cullen, JM | 1 |
| Seiler, GS | 1 |
| Lunn, KF | 1 |
| Mathews, KG | 1 |
| Gookin, JL | 1 |
| Grossman, A | 1 |
| Johannsson, G | 1 |
| Quinkler, M | 1 |
| Zelissen, P | 1 |
| Diamanti-Kandarakis, E | 1 |
| Dattilo, M | 1 |
| Macut, D | 1 |
| Duntas, L | 1 |
| Gonos, ES | 1 |
| Goulis, DG | 1 |
| Gantenbein, CK | 1 |
| Kapetanou, M | 1 |
| Koukkou, E | 1 |
| Lambrinoudaki, I | 1 |
| Michalaki, M | 1 |
| Eftekhari-Nader, S | 1 |
| Pasquali, R | 1 |
| Peppa, M | 1 |
| Tzanela, M | 1 |
| Vassilatou, E | 1 |
| Vryonidou, A | 1 |
| Maggi, M | 1 |
| Buvat, J | 1 |
| Corona, G | 1 |
| Guay, A | 1 |
| Torres, LO | 1 |
| Drbalová, K | 1 |
| Matucha, P | 1 |
| Matějková-Běhanová, M | 1 |
| Bílek, R | 1 |
| Kříž, L | 1 |
| Kazihnitková, H | 1 |
| Hampl, R | 1 |
| Földes, J | 2 |
| Fehér, T | 2 |
| Fehér, KG | 1 |
| Kollin, E | 1 |
| Bodrogi, L | 1 |
| Bassi, F | 1 |
| Pupi, A | 1 |
| Giannotti, P | 1 |
| Fiorelli, G | 1 |
| Forti, G | 1 |
| Pinchera, A | 1 |
| Serio, M | 1 |
| Webb, SJ | 1 |
| Xiao, GH | 1 |
| Geoghegan, TE | 1 |
| Prough, RA | 1 |
| Bobyleva, V | 1 |
| Bellei, M | 1 |
| Kneer, N | 2 |
| Lardy, H | 2 |
| Tagawa, N | 2 |
| Tamanaka, J | 1 |
| Fujinami, A | 1 |
| Kobayashi, Y | 2 |
| Takano, T | 2 |
| Fukata, S | 2 |
| Kuma, K | 2 |
| Tada, H | 2 |
| Amino, N | 2 |
| Izumi, Y | 1 |
| Bicíková, M | 1 |
| Tallová, J | 1 |
| Hill, M | 1 |
| Vañuga, A | 1 |
| Putz, Z | 1 |
| Tomandl, J | 1 |
| Gerhard, I | 1 |
| Eggert-Kruse, W | 1 |
| Merzoug, K | 1 |
| Klinga, K | 1 |
| Runnebaum, B | 1 |
| Littley, MD | 1 |
| Pollock, A | 1 |
| Kane, J | 1 |
| Shalet, SM | 1 |
| Andó, S | 1 |
| Panno, ML | 1 |
| Beraldi, E | 1 |
| Tarantino, G | 1 |
| Salerno, M | 1 |
| Palmero, S | 1 |
| Prati, M | 1 |
| Fugassa, E | 1 |
| Bársony, J | 1 |
| Lakatos, P | 1 |
| Sneddon, A | 1 |
| Steel, JM | 1 |
| Strong, JA | 1 |
| Goldfine, I | 1 |
| Rosenfield, R | 1 |
| Landau, RL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Antioxidants vs.Ovarian Bio-stimulation Therapy to Rescue the Ovarian Reserve[NCT03621683] | 78 participants (Actual) | Interventional | 2016-01-06 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for dehydroepiandrosterone and Central Hypothyroidism
| Article | Year |
|---|---|
Therapy of endocrine disease: Perspectives on the management of adrenal insufficiency: clinical insights from across Europe.
Topics: Addison Disease; Adrenal Insufficiency; Cardiovascular Diseases; Circadian Rhythm; Dehydroepiandrost | 2013 |
MECHANISMS IN ENDOCRINOLOGY: Aging and anti-aging: a Combo-Endocrinology overview.
Topics: Adjuvants, Immunologic; Aging; Androgens; Antioxidants; Circadian Rhythm; Dehydroepiandrosterone; Di | 2017 |
Hormonal causes of male sexual dysfunctions and their management (hyperprolactinemia, thyroid disorders, GH disorders, and DHEA).
Topics: Acromegaly; Adrenal Insufficiency; Dehydroepiandrosterone; Gonadotropins; Hormone Replacement Therap | 2013 |
19 other studies available for dehydroepiandrosterone and Central Hypothyroidism
| Article | Year |
|---|---|
[Endocrine disorders after combined chemoradiotherapy in Hodgkin Lymphoma survivors].
Topics: Adult; Chemoradiotherapy; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Hodgkin Dise | 2023 |
Impact of dehydroepiandrosterone on thyroid autoimmunity and function in men with autoimmune hypothyroidism.
Topics: Aged; Autoimmunity; Dehydroepiandrosterone; Humans; Hypothyroidism; Male; Thyroid Hormones; Thyrotro | 2021 |
Dehydroepiandrostenedione sulphate (DHEAS) levels predict high risk of rheumatoid arthritis (RA) in subclinical hypothyroidism.
Topics: Aged; Arthritis, Rheumatoid; Dehydroepiandrosterone; Female; Humans; Hypothyroidism; Male; Retrospec | 2021 |
Investigation of adrenal and thyroid gland dysfunction in dogs with ultrasonographic diagnosis of gallbladder mucocele formation.
Topics: Adrenal Glands; Adrenocortical Hyperfunction; Animals; Autoantibodies; Case-Control Studies; Dehydro | 2019 |
Immunoprotective steroids and SHBG in non-treated hypothyroidism and their relationship to autoimmune thyroid disorders.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoimmunity; Dehydroepiandrosterone; Female; Humans; Hy | 2008 |
Dehydroepiandrosterone sulphate (DS), dehydroepiandrosterone (D) and "free" dehydroepiandrosterone (FD) in the plasma of patients with thyroid diseases.
Topics: Adrenal Cortex; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Graves Diseas | 1983 |
Plasma dehydroepiandrosterone sulphate in hypothyroid premenopausal women.
Topics: Adult; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hypothyroidism; Middle Aged; Prolacti | 1980 |
Regulation of CYP4A expression in rat by dehydroepiandrosterone and thyroid hormone.
Topics: Animals; Blotting, Northern; Blotting, Western; Cell Fractionation; Cells, Cultured; Cytochrome P-45 | 1996 |
The effects of the ergosteroid 7-oxo-dehydroepiandrosterone on mitochondrial membrane potential: possible relationship to thermogenesis.
Topics: Animals; Cell Respiration; Dehydroepiandrosterone; Glycerophosphates; Hyperthyroidism; Hypothyroidis | 1997 |
Thyroid hormone and dehydroepiandrosterone permit gluconeogenic hormone responses in hepatocytes.
Topics: Aminooxyacetic Acid; Animals; Calcium; Cyclic AMP; Dehydroepiandrosterone; Glucagon; Gluconeogenesis | 2000 |
Serum dehydroepiandrosterone, dehydroepiandrosterone sulfate, and pregnenolone sulfate concentrations in patients with hyperthyroidism and hypothyroidism.
Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hyperthyroidism; Hypo | 2000 |
Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism.
Topics: Adult; Androstenediol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hyper | 2001 |
Effect of treatment of hypothyroidism on the plasma concentrations of neuroactive steroids and homocysteine.
Topics: Adjuvants, Immunologic; Adult; Aged; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradi | 2001 |
Thyrotropin-releasing hormone (TRH) and metoclopramide testing in infertile women.
Topics: Dehydroepiandrosterone; Dopamine Agents; Estradiol; Female; Fertilization; Follicle Stimulating Horm | 1991 |
Basal serum dehydroepiandrosterone sulphate concentration does not predict the cortisol response to provocative testing.
Topics: Adolescent; Adult; Aged; Cushing Syndrome; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; F | 1990 |
Influence of hypothyroidism on in-vitro testicular steroidogenesis in adult rats.
Topics: Androstenedione; Animals; Body Weight; Dehydroepiandrosterone; Dihydrotestosterone; Glucosephosphate | 1990 |
Effect of vitamin D3 loading and thyroid hormone replacement therapy on the decreased serum 25-hydroxyvitamin D level in patients with hypothyroidism.
Topics: Adolescent; Adult; Aged; Calcifediol; Cholecalciferol; Dehydroepiandrosterone; Dehydroepiandrosteron | 1986 |
Effect of thyroid funtion and of obesity on discriminant function for mammary carcinoma.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Androgens; Androsterone; Breast Neoplasms; | 1968 |
Hyperleydigism: a cause of severe pubertal gynecomastia.
Topics: 17-Ketosteroids; Adolescent; Dehydroepiandrosterone; Diabetes Insipidus; Estradiol; Feedback; Gyneco | 1971 |