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dehydroepiandrosterone and Cardiac Failure

dehydroepiandrosterone has been researched along with Cardiac Failure in 17 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
"The secretion of dehydroepiandrosterone sulfate (DHEAS) decreases with age, and the incidence of heart failure rises in the elderly population."7.74Dehydroepiandrosterone levels vary according as heart failure condition in patients with idiopathic dilated cardiomyopathy. ( Kawano, H; Kinoshita, Y; Nagayoshi, Y; Ogawa, H; Soejima, H; Tanaka, Y; Yamabe, H, 2008)
"To analyze the association of circulating dehydroepiandrosterone sulfate (DHEA-S) levels with cardiovascular outcomes in patients with chronic Chagas cardiomyopathy (CCM) diagnosis."4.12Circulating DHEA-S levels and major cardiovascular outcomes in chronic Chagas cardiomyopathy: A prospective cohort study. ( Bautista-Niño, PK; Echeverría, LE; Eisenga, MF; Gómez-Ochoa, SA; Hunziker, L; Muka, T; Rojas, LZ, 2022)
"The secretion of dehydroepiandrosterone sulfate (DHEAS) decreases with age, and the incidence of heart failure rises in the elderly population."3.74Dehydroepiandrosterone levels vary according as heart failure condition in patients with idiopathic dilated cardiomyopathy. ( Kawano, H; Kinoshita, Y; Nagayoshi, Y; Ogawa, H; Soejima, H; Tanaka, Y; Yamabe, H, 2008)
"The relation between adrenal steroid hormone imbalance, as quantified by the cortisol/dehydroepiandrosterone (DHEA) ratio, and hemoglobin concentrations was appraised in 92 men with stable chronic heart failure (CHF)."3.73Association of deranged adrenal steroid metabolism with anemia in chronic heart failure. ( Anker, SD; Cicoira, M; Coats, AJ; Crosato, M; Doehner, W; John, M; Kalra, PR; Okonko, DO; Poole-Wilson, PA, 2005)
"We sought to assess the possible relations between clinical severity of chronic heart failure and catabolic factors, specifically tumor necrosis factor (TNF), soluble TNF receptors 1 and 2 (sTNFR-1 and sTNFR-2), cortisol, testosterone and dehydroepiandrosterone (DHEA)."3.69Tumor necrosis factor and steroid metabolism in chronic heart failure: possible relation to muscle wasting. ( Anker, SD; Clark, AL; Coats, AJ; Hellewell, PG; Kemp, M; Salsbury, C; Teixeira, MM, 1997)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's2 (11.76)18.2507
2000's7 (41.18)29.6817
2010's3 (17.65)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Rojas, LZ1
Gómez-Ochoa, SA1
Echeverría, LE1
Bautista-Niño, PK1
Hunziker, L1
Eisenga, MF1
Muka, T1
Yeap, BB1
Dwivedi, G1
Zhang, YT1
Xue, JJ1
Wang, Q1
Cheng, SY1
Chen, ZC1
Li, HY1
Shan, JJ1
Cheng, KL1
Zeng, WJ1
Thierer, J1
Acosta, A1
Vainstein, N1
Sultan, M1
Francesia, A1
Marino, J1
Prado, AH1
Guglielmone, R1
Trivi, M1
Boero, L1
Brites, F1
Anker, S1
Pastor-Pérez, FJ1
Manzano-Fernández, S1
Garrido Bravo, IP1
Nicolás, F1
Tornel, PL1
Lax, A1
de la Morena, G1
Valdés, M1
Pascual-Figal, DA1
Moyad, MA1
Nakamura, S1
Yoshimura, M4
Nakayama, M1
Ito, T1
Mizuno, Y1
Harada, E1
Sakamoto, T1
Saito, Y1
Nakao, K1
Yasue, H1
Ogawa, H2
Okonko, DO1
Crosato, M1
Kalra, PR1
Cicoira, M1
John, M1
Doehner, W1
Coats, AJ3
Poole-Wilson, PA2
Anker, SD3
Kawano, H1
Nagayoshi, Y1
Soejima, H1
Tanaka, Y1
Yamabe, H1
Kinoshita, Y1
Clark, AL2
Kemp, M1
Salsbury, C1
Teixeira, MM1
Hellewell, PG1
Niebauer, J1
Pflaum, CD1
Strasburger, CJ1
Hooper, J1
Wolff, HP1
Zaretskiĭ, MM1
Vakhtina, TI1
Smith, TW1
Haber, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Relationship Between Right Atrial Volume Index, Functional Capacity and Inflammatory Biomarkers in Patients With Chronic Obstructive Lung Disease and Right Heart Affection.[NCT05366400]151 participants (Actual)Observational2022-01-19Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for dehydroepiandrosterone and Cardiac Failure

ArticleYear
The placebo effect and randomized trials: analysis of alternative medicine.
    The Urologic clinics of North America, 2002, Volume: 29, Issue:1

    Topics: Androstenedione; Antioxidants; beta Carotene; Coenzymes; Complementary Therapies; Dehydroepiandroste

2002
[Heart failure and renin-angiotensin-aldosterone system: studies on aldosterone].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2005, Feb-10, Volume: 94, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Apoptosis; Dehydroepiandrosterone; Gene Expression Regulation,

2005
[Aldosterone in heart failure].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2005, Volume: 126, Issue:6

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Apoptosis; Cytochrome P-450 CYP11

2005
[Cardiac aldosterone].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64, Issue:5

    Topics: Aldosterone; Dehydroepiandrosterone; Heart Failure; Humans

2006
[Clinical steroid analysis, using H3 and C14 (determination of their secretion, plasma concentration, secretion rate, as well as metabolism and renal clearance rate)].
    Nuclear-Medizin, 1965

    Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Aldosterone; Carbon Isotopes; Chemistry, Clin

1965

Other Studies

12 other studies available for dehydroepiandrosterone and Cardiac Failure

ArticleYear
Circulating DHEA-S levels and major cardiovascular outcomes in chronic Chagas cardiomyopathy: A prospective cohort study.
    International journal of cardiology, 2022, Feb-15, Volume: 349

    Topics: Biomarkers; Cardiomyopathies; Chagas Cardiomyopathy; Chagas Disease; Dehydroepiandrosterone; Female;

2022
Androgens and Heart Failure: New Observations Illuminating an Aging Conundrum.
    The Journal of clinical endocrinology and metabolism, 2021, 03-08, Volume: 106, Issue:3

    Topics: Aging; Androgens; Androstenedione; Dehydroepiandrosterone; Heart Failure; Humans

2021
Dehydroepiandrosterone attenuates pulmonary artery and right ventricular remodeling in a rat model of pulmonary hypertension due to left heart failure.
    Life sciences, 2019, Feb-15, Volume: 219

    Topics: Animals; Blotting, Western; Dehydroepiandrosterone; Disease Models, Animal; Echocardiography; Heart

2019
Relation of left ventricular ejection fraction and functional capacity with metabolism and inflammation in chronic heart failure with reduced ejection fraction (from the MIMICA Study).
    The American journal of cardiology, 2010, Apr-01, Volume: 105, Issue:7

    Topics: Adiponectin; Aged; C-Reactive Protein; Chronic Disease; Dehydroepiandrosterone; Female; Heart Failur

2010
Anabolic status and functional impairment in men with mild chronic heart failure.
    The American journal of cardiology, 2011, Sep-15, Volume: 108, Issue:6

    Topics: Chronic Disease; Dehydroepiandrosterone; Echocardiography; Electrocardiography; Exercise Test; Exerc

2011
Possible association of heart failure status with synthetic balance between aldosterone and dehydroepiandrosterone in human heart.
    Circulation, 2004, Sep-28, Volume: 110, Issue:13

    Topics: Adult; Aged; Aldosterone; Animals; Blotting, Southern; Cardiac Catheterization; Cell Size; Cells, Cu

2004
Association of deranged adrenal steroid metabolism with anemia in chronic heart failure.
    The American journal of cardiology, 2005, Jul-01, Volume: 96, Issue:1

    Topics: Adrenal Glands; Aged; Anemia; Dehydroepiandrosterone; Heart Failure; Hemoglobins; Humans; Hydrocorti

2005
Dehydroepiandrosterone levels vary according as heart failure condition in patients with idiopathic dilated cardiomyopathy.
    International journal of cardiology, 2008, Apr-10, Volume: 125, Issue:2

    Topics: Aged; Biomarkers; Cardiomyopathy, Dilated; Dehydroepiandrosterone; Heart Failure; Humans; Male; Midd

2008
Tumor necrosis factor and steroid metabolism in chronic heart failure: possible relation to muscle wasting.
    Journal of the American College of Cardiology, 1997, Volume: 30, Issue:4

    Topics: Aged; Antigens, CD; Body Mass Index; Case-Control Studies; Dehydroepiandrosterone; Exercise Test; He

1997
Deficient insulin-like growth factor I in chronic heart failure predicts altered body composition, anabolic deficiency, cytokine and neurohormonal activation.
    Journal of the American College of Cardiology, 1998, Volume: 32, Issue:2

    Topics: Adrenergic alpha-Agonists; Age Factors; Aged; Anatomy, Cross-Sectional; Body Composition; Body Mass

1998
[Protein composition of the blood and excretion of corticosteroids in patients with arteriosclerotic cardiosclerosis with chronic circulatory insufficiency].
    Kardiologiia, 1969, Volume: 9, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Blood Proteins; Coronary Diseas

1969
The clinical value of serum digitalis glycoside concentrations in the evaluation of drug toxicity.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Adult; Aged; Antibody Specificity; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Cho

1971