dehydroepiandrosterone has been researched along with Breast Neoplasms in 330 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A group of 122 postmenopausal patients with histologically proven node-positive primary breast cancer have been randomized to receive aminoglutethimide-hydrocortisone or placebo aminoglutethimide-placebo hydrocortisone for 2 years." | 9.05 | Adjuvant aminoglutethimide therapy for postmenopausal patients with primary breast cancer: progress report. ( Bettelheim, R; Chilvers, C; Coombes, RC; Dowsett, M; Ford, HT; Gazet, JC; Gordon, C; Powles, TJ; Smith, IE; Zava, D, 1982) |
| "The effect of the dose of aminoglutethimide on the suppression of oestrone, oestradiol and dehydroepiandrosterone sulphate (DHAS) levels was studied in 36 women with advanced postmenopausal breast cancer, all of whom received 20 mg hydrocortisone twice daily as replacement glucocorticoid." | 9.05 | Aminoglutethimide dose and hormone suppression in advanced breast cancer. ( Dowsett, M; Harris, AL; Jeffcoate, SL; Smith, IE, 1983) |
| "The endocrine effects of replacement doses of hydrocortisone in postmenopausal women with advanced breast cancer were compared with the same doses of hydrocortisone plus aminoglutethimide." | 9.05 | Hydrocortisone alone vs hydrocortisone plus aminoglutethimide: a comparison of the endocrine effects in postmenopausal breast cancer. ( Dowsett, M; Harris, AL; Jeffcoate, S; Smith, IE, 1984) |
| "Various plasma hormones were measured in 13 pre- and 20 post-menopausal women with advanced breast cancer before and for 12 months after ovarian irradiation or during continuous administration of tamoxifen at a dose of 10 mg twice a day, respectively; some patients received additional prednisolone at a dose of 5 mg twice a day." | 9.05 | Effect of prednisolone on hormone profiles during primary endocrine treatment of advanced breast cancer. ( Blackburn, AM; Bulbrook, RD; Hoare, SA; Kwa, HG; Rubens, RD; Thomas, BS; Wang, DY, 1984) |
| "The purpose of this study is to elucidate how patient-reported cognitive symptoms manifest from variations in hormone levels or precursors such as dehydroepiandrosterone (DHEA) and its sulfated form [collectively termed as DHEA(S)] and to investigate their association in breast cancer survivors." | 8.12 | Longitudinal evaluation of dehydroepiandrosterone (DHEA), its sulfated form and estradiol with cancer-related cognitive impairment in early-stage breast cancer patients receiving chemotherapy. ( Chan, A; Lau, AJ; Parajuli, R; Tan, CJ; Toh, YL; Yap, NY, 2022) |
| "To measure the association between alcohol intake and 11 hormones and peptides in postmenopausal breast cancer survivors and to evaluate whether this association differs by tamoxifen use." | 7.74 | Association between alcohol intake and serum sex hormones and peptides differs by tamoxifen use in breast cancer survivors. ( Ballard-Barbash, R; Baumgartner, KB; Baumgartner, RN; Bernstein, L; Gilliland, F; Koprowski, C; McTiernan, A; Neuhouser, ML; Ulrich, CM; Wayne, S; Wiggins, C, 2008) |
| "Epidemiological and experimental studies suggest that dehydroepiandrosterone (DHEA) exerts a protective effect against breast cancer." | 7.69 | Role of glucose-6-phosphate dehydrogenase inhibition in the antiproliferative effects of dehydroepiandrosterone on human breast cancer cells. ( Boccuzzi, G; Brignardello, E; Di Monaco, M; Gallo, M; Gatto, V; Leonardi, L; Pizzini, A, 1997) |
| "Dehydroepiandrosterone and dehydroepiandrosterone sulfate are steroids which may be associated with the development of breast cancer." | 7.68 | Relationship of prediagnostic serum levels of dehydroepiandrosterone and dehydroepiandrosterone sulfate to the risk of developing premenopausal breast cancer. ( Alberg, AJ; Bush, TL; Comstock, GW; Gordon, GB; Helzlsouer, KJ, 1992) |
| "It has been suggested that dehydroepiandrosterone (DHEA) and its sulfate ester, dehydroepiandrosterone sulfate (DHEAS), have a protective effect against breast cancer." | 7.68 | Dehydroepiandrosterone sulfate and breast cancer risk. ( Barrett-Connor, E; Friedlander, NJ; Khaw, KT, 1990) |
| "The clinical and endocrine effects of low-dose aminoglutethimide without hydrocortisone in patients with advanced breast cancer were investigated." | 7.67 | Low-dose aminoglutethimide in treatment of advanced breast cancer. ( Bozek, T; Carr, L; Dowsett, M; Gazet, JC; Jeffcoate, SL; Kurkure, A; McKinna, JA; Smith, IE; Stuart-Harris, R, 1984) |
| "About one third of unselected postmenopausal women with advanced breast cancer respond to treatment with aminoglutethimide and hydrocortisone, but they all eventually relapse, and further progression of disease occurs." | 7.67 | Endocrine changes associated with relapse in advanced breast cancer patients on aminoglutethimide therapy. ( Dowsett, M; Harris, AL; Jeffcoate, SL; Smith, IE, 1984) |
| "The aim of this study is to report on Aminoglutethimide-induced hormonal modifications in advanced breast cancer." | 7.67 | Preliminary study of hormone determinations during aminoglutethimide therapy for advanced breast cancer. ( Díaz, L; Koliren, L; Loruso, A; Ramos, G; Scaglia, HE; Soto, E; Zylbersztein, C, 1984) |
| "Plasma concentrations of dehydroepiandrosterone (DHA), DHA-sulphate (DHAS) and 7 alpha hydroxy-DHA (7 alpha OHDHA) were measured and compared with tumor estrogen receptor (ER) status in 33 postmenopausal patients with breast cancer." | 7.67 | Estrogen receptor status, adrenal androgens and 7 alpha-hydroxydehydroepiandrosterone in breast cancer patients. ( Couch, RA; Holdaway, IM; Kay, RG; Mason, BH; Skinner, SJ, 1984) |
| " Tamoxifen, an anti-estrogen, is used in the treatment of women with breast cancer in whom metastatic disease has been demonstrated." | 7.67 | Effects of tamoxifen on testosterone metabolism in postmenopausal women with breast cancer. ( Bird, CE; Clark, AF; Masters, V; Sterns, EE, 1985) |
| "The possibility that medroxyprogesterone acetate (MPA) is clinically effective at least in part by its suppression of adrenal steroidogenesis and a resultant reduction of circulating oestrogen levels was investigated in 49 postmenopausal patients with advanced breast cancer." | 7.67 | The effects of low and high dose medroxyprogesterone acetate on sex steroids and sex hormone binding globulin in postmenopausal breast cancer patients. ( Dowsett, M; Jeffcoate, SL; Lal, A; Smith, IE, 1987) |
| "A short review is given about some of the data reported in the literature on dehydroepiandrosterone and its derivatives, delta 5-androstenediol (hermaphrodiol) and sexual steroid binding globulin (SHBG) in breast cancer patients." | 7.67 | [Dehydroepiandrosterone and other endocrine parameters in breast cancer]. ( Dässler, CG; Wilken, H, 1987) |
| "In North American women at low or high risk of developing breast cancer, as assessed by an epidemiologic questionnaire, the plasma concentration of dehydroepiandrosterone sulfate shows a statistically significant circannual variation." | 7.67 | [Blood levels of dehydroepiandrosterone sulfate (DHEA-S) and the risk of breast cancer]. ( Baulieu, EE; Cassanas, G; Gomes, P; Halberg, F; Haus, E; Hermida, R; Lakatua, D; Robel, P, 1988) |
| "A phase II study with cyproterone acetate (CPA) was done as the primary treatment in female breast cancer patients." | 7.67 | Clinical and endocrine effects of cyproterone acetate in postmenopausal patients with advanced breast cancer. ( de Vries, EG; Dikkeschei, LD; Mulder, NH; Sleijfer, DT; van der Ploeg, E; Willemse, PH, 1988) |
| "Reports of estrone (E1) and dehydroepiandrosterone (DHEA) sulfatase (sulfohydrolase) activities within many human breast cancers have prompted us to undertake the identification and partial characterization of these enzyme activities within MCF-7 human breast cancer cells." | 7.67 | The hydrolysis of estrone sulfate and dehydroepiandrosterone sulfate by MCF-7 human breast cancer cells. ( MacIndoe, JH, 1988) |
| "Hormonal changes induced by the pure antiandrogen flutamide were studied in three postmenopausal metastatic breast cancer patients." | 7.67 | Hormonal changes induced by the pure antiandrogen flutamide in postmenopausal women with advanced breast cancer. ( Ballerini, P; Fariselli, G; Recchione, C; Secreto, G; Zambetti, M, 1988) |
| "Aminoglutethimide in combination with hydrocortisone provides an effective therapy in postmenopausal advanced breast cancer patients, with response rates of 37." | 7.66 | Endocrine and therapeutic effects of aminoglutethimide in premenopausal patients with breast cancer. ( Dowsett, M; Harris, AL; Jeffcoate, SL; McKinna, JA; Morgan, M; Smith, IE, 1982) |
| "Peripheral serum levels of cortisol, dehydroepiandrosterone (DHA), dehydroepiandrosterone sulphate (DHA-S), oestradiol-17 beta and total oestrone were measured in 17 postmenopausal breast cancer patients and on age-matched healthy controls." | 7.66 | Effects of tamoxifen on the serum levels of oestrogens and adrenocortical steroids in postmenopausal breast cancer patients. ( Carlström, K; Sköldefors, H; Theve, NO; Wallgren, A; Wilking, N, 1982) |
| "Cortisol and dehydroepiandrosterone sulphate (DHAS) were measured in saliva from postmenopausal women with primary breast cancer and a control group of comparable age." | 7.66 | Salivary cortisol and dehydroepiandrosterone sulphate levels in postmenopausal women with primary breast cancer. ( Blamey, RW; Campbell, FC; Griffiths, K; Holliday, HW; Read, GF; Wilson, DW, 1983) |
| "Sixty-five patients with actively progressing advanced breast cancer were treated with aminoglutethimide, a drug which inhibits adrenal steroid synthesis and decreases peripheral conversion of androgens to oestrogens." | 7.66 | Medical adrenalectomy with aminoglutethimide in the management of advanced breast cancer. ( Jerums, G; Murray, RM; Pitt, P, 1981) |
| "The 24-hr mean plasma concentrations of dehydroisoandrosterone (DHA) and dehydroisoandrosterone sulfate were measured in 11 women with primary operable breast cancer, ages 31 to 78 years, and in 37 normal women, ages 21 to 75 years." | 7.66 | Abnormal 24-hr mean plasma concentrations of dehydroisoandrosterone and dehydroisoandrosterone sulfate in women with primary operable breast cancer. ( Fukushima, DK; Levin, J; Markham, M; Rosenfeld, RS; Strain, GW; Zumoff, B, 1981) |
| " treatment with dehydroepiandrosterone, an adrenal steroid found in subnormal plasma concentrations in women predisposed to develop breast cancer, inhibits the formation of spontaneous mammary cancer in female C3H(Avy/a) mice." | 7.66 | Inhibition of spontaneous breast cancer formation in female C3H(Avy/a) mice by long-term treatment with dehydroepiandrosterone. ( Schwartz, AG, 1979) |
| "Comparative investigations of the urinary excretion of different 17-ketosteroids in healthy women and patients suffering from mastopathia fibrocystica and/or mammary carcinomas had the following results: 1." | 7.65 | The excretion of 17-ketosteroids in patients suffering from mastopathia fibrocystica and mammary carcinomas. ( Görlich, M; Heise, E; Hindy, I; Pradja, N, 1975) |
| "Calusterone (7beta, 17alpha-dimethyltestosterone) is a 17-alkylated, orally active androgenic steroid used in the treatment of breast cancer." | 7.65 | The effect of 7beta, 17alpha-dimethyltestosterone (calusteron) on testosterone metabolism in women with advanced breast cancer. ( Bradlow, HL; Hellman, L; Levin, J; Zumoff, B, 1977) |
| "Mechanisms by which DHEA may promote breast cancer relate to its effect in increasing circulating IGF-I, by inhibiting the suppressive effect of glucocorticoids, and by promoting retention of pre-adipocytes with aromatase activity." | 6.82 | Functions of dehydroepiandrosterone in relation to breast cancer. ( Chatterton, RT, 2022) |
| "40), but not for MPA and estrone, indicating better adrenal suppression by higher MPA dosage and plasma levels." | 6.66 | Endocrine effects of medroxyprogesterone acetate: relation between plasma levels and suppression of adrenal steroids in patients with breast cancer. ( Doorenbos, H; Sleijfer, DT; Sluiter, WJ; van Veelen, H; Willemse, PH, 1985) |
| "Late promotion of breast cancer in postmenopausal women may be stimulated by prolonged intake of DHEA, and the risk may be increased by the endocrine abnormality associated with pre-existing abdominal obesity." | 6.40 | Dietary supplements of dehydroepiandrosterone in relation to breast cancer risk. ( Stoll, BA, 1999) |
| " While this regimen effectively blocked adrenal function, it was complicated by a drug interaction in which aminoglutethimide accelerated the metabolism and reduced the bioavailability of dexamethasone." | 6.36 | Kinetic, hormonal and clinical studies with aminoglutethimide in breast cancer. ( Harvey, H; Kendall, J; Lipton, A; Ruby, EB; Samojlik, E; Santen, RJ; Wells, SA, 1977) |
| "Eighty-one patients with early-stage breast cancer (stages I-III) who had no prior exposure to chemotherapy and/or radiotherapy and were scheduled to receive anthracycline-based or taxane-based chemotherapy treatment with curative intent." | 5.51 | Prechemotherapy Levels of Plasma Dehydroepiandrosterone and Its Sulfated Form as Predictors of Cancer-Related Cognitive Impairment in Patients with Breast Cancer Receiving Chemotherapy. ( Bansal, S; Chan, A; Lau, AJ; Shariq Mujtaba, J; Shwe, M; Toh, YL; Yeo, A, 2019) |
| "Dehydroepiandrosterone (DHEA) has a protective role against cancer, however, the mechanism by which DHEA has this effect remains poorly understood." | 5.37 | Effects of dehydroepiandrosterone on proliferation, migration, and death of breast cancer cells. ( Contreras, PG; Dillon, JS; López-Marure, R, 2011) |
| "Serum DHEA also has been related to breast cancer in postmenopausal women, but the relationship of ADIOL to risk has not been evaluated previously." | 5.30 | Relationship of serum dehydroepiandrosterone (DHEA), DHEA sulfate, and 5-androstene-3 beta, 17 beta-diol to risk of breast cancer in postmenopausal women. ( Chang, L; Dorgan, JF; Falk, RT; Franz, C; Kahle, L; Longcope, C; Miller, R; Stanczyk, FZ; Stephenson, HE, 1997) |
| "Dehydroepiandrosterone (DHEA) has been shown to affect the growth of mammary carcinomas both in vitro and in vivo." | 5.29 | Dehydroepiandrosterone concentration in breast cancer tissue is related to its plasma gradient across the mammary gland. ( Boccuzzi, G; Brignardello, E; Cassoni, P; Di Monaco, M; Massobrio, M; Migliardi, M; Pizzini, A, 1995) |
| "Reports that MCF-7 human breast cancer cells can transform both estrone (E1)1 to estradiol (E2) and dehydroepiandrosterone (DHEA) to the estrogenic steroid 5-androstenediol (AED), have prompted us to investigate the 17-ketosteroid reductase activities (17-KSR's) which mediate these potentially important reactions." | 5.28 | Dehydroepiandrosterone and estrone 17-ketosteroid reductases in MCF-7 human breast cancer cells. ( Hinkhouse, M; MacIndoe, JH; Woods, G, 1990) |
| "Aminoglutethimide (Ag) has been used in different dosages with and without combined treatment with glucocorticoids for the suppression of peripheral plasma levels of steroidal hormones." | 5.27 | Endocrine effects of aminoglutethimide plus hydrocortisone versus effects of high dose of hydrocortisone alone in postmenopausal metastatic breast cancer. ( Alexieva-Figusch, J; de Jong, FH; Klign, JG; Lamberts, WJ; van Gilse, HA, 1987) |
| "Ketoconazole was poorly tolerated due to gastrointestinal toxicity." | 5.27 | High dose ketoconazole: endocrine and therapeutic effects in postmenopausal breast cancer. ( Cantwell, BM; Dowsett, M; Harris, AL, 1988) |
| "Enzymic Synthesis of Steroid Sulfate by Mammary Cancer and Its Clinical Implications." | 5.26 | Dehydroepiandrosterone sulfotransferase as a possible shunt for the control of steroid metabolism in human mammary carcinoma. ( Adams, JB; Chandra, DP, 1977) |
| "Serum levels of cortisol (C), androstenedione (A), dehydroepiandrosterone (D), estrone (E1) and estradiol (E2) were chosen as parameters to compare the bioavailability of megestrol acetate (MA) and medroxyprogesterone acetate (MPA) in postmenopausal patients with advanced breast cancer." | 5.06 | Adrenal steroids as parameters of the bioavailability of MA and MPA. ( Dikkeschei, LD; Sleijfer, DT; Tjabbes, T; van Veelen, H; Willemse, PH, 1990) |
| "A group of 122 postmenopausal patients with histologically proven node-positive primary breast cancer have been randomized to receive aminoglutethimide-hydrocortisone or placebo aminoglutethimide-placebo hydrocortisone for 2 years." | 5.05 | Adjuvant aminoglutethimide therapy for postmenopausal patients with primary breast cancer: progress report. ( Bettelheim, R; Chilvers, C; Coombes, RC; Dowsett, M; Ford, HT; Gazet, JC; Gordon, C; Powles, TJ; Smith, IE; Zava, D, 1982) |
| "The effect of the dose of aminoglutethimide on the suppression of oestrone, oestradiol and dehydroepiandrosterone sulphate (DHAS) levels was studied in 36 women with advanced postmenopausal breast cancer, all of whom received 20 mg hydrocortisone twice daily as replacement glucocorticoid." | 5.05 | Aminoglutethimide dose and hormone suppression in advanced breast cancer. ( Dowsett, M; Harris, AL; Jeffcoate, SL; Smith, IE, 1983) |
| "The endocrine effects of replacement doses of hydrocortisone in postmenopausal women with advanced breast cancer were compared with the same doses of hydrocortisone plus aminoglutethimide." | 5.05 | Hydrocortisone alone vs hydrocortisone plus aminoglutethimide: a comparison of the endocrine effects in postmenopausal breast cancer. ( Dowsett, M; Harris, AL; Jeffcoate, S; Smith, IE, 1984) |
| "Various plasma hormones were measured in 13 pre- and 20 post-menopausal women with advanced breast cancer before and for 12 months after ovarian irradiation or during continuous administration of tamoxifen at a dose of 10 mg twice a day, respectively; some patients received additional prednisolone at a dose of 5 mg twice a day." | 5.05 | Effect of prednisolone on hormone profiles during primary endocrine treatment of advanced breast cancer. ( Blackburn, AM; Bulbrook, RD; Hoare, SA; Kwa, HG; Rubens, RD; Thomas, BS; Wang, DY, 1984) |
| "The first-generation selective estrogen receptor modulator (SERM) tamoxifen has been the mainstream hormone therapy in breast cancer." | 4.84 | Drug insight: breast cancer prevention and tissue-targeted hormone replacement therapy. ( Labrie, F, 2007) |
| "The risk for breast cancer increased statistically significantly with increasing concentrations of all sex hormones examined: total estradiol, free estradiol, non-sex hormone-binding globulin (SHBG)-bound estradiol (which comprises free and albumin-bound estradiol), estrone, estrone sulfate, androstenedione, dehydroepiandrosterone, dehydroepiandrosterone sulfate, and testosterone." | 4.81 | Endogenous sex hormones and breast cancer in postmenopausal women: reanalysis of nine prospective studies. ( Appleby, P; Barnes, I; Key, T; Reeves, G, 2002) |
| "The purpose of this study is to elucidate how patient-reported cognitive symptoms manifest from variations in hormone levels or precursors such as dehydroepiandrosterone (DHEA) and its sulfated form [collectively termed as DHEA(S)] and to investigate their association in breast cancer survivors." | 4.12 | Longitudinal evaluation of dehydroepiandrosterone (DHEA), its sulfated form and estradiol with cancer-related cognitive impairment in early-stage breast cancer patients receiving chemotherapy. ( Chan, A; Lau, AJ; Parajuli, R; Tan, CJ; Toh, YL; Yap, NY, 2022) |
| "Salivary hormone levels of testosterone (T), Estradiol (E2), Progesterone (P), Estriol (E3), Estrone (E1), DHEAS and Cortisol (C) were measured by Enzyme Immunoassay (EIA) in 357 women with histologically verified breast cancer and 184 age-matched control women." | 3.76 | Low salivary testosterone levels in patients with breast cancer. ( Antsaklis, A; Dimitrakakis, C; Glaser, R; Marinopoulos, S; Tsigginou, A; Zava, D, 2010) |
| " The present study was undertaken to assess the presence of potential cancer biomarkers, their variation among individuals at high risk for breast cancer, and differences associated with menopause and tamoxifen treatment." | 3.76 | Breast ductal lavage for assessment of breast cancer biomarkers. ( Bryk, M; Chatterton, RT; Habe-Evans, M; Khan, SA; Parker, NP; Scholtens, DM, 2010) |
| "To measure the association between alcohol intake and 11 hormones and peptides in postmenopausal breast cancer survivors and to evaluate whether this association differs by tamoxifen use." | 3.74 | Association between alcohol intake and serum sex hormones and peptides differs by tamoxifen use in breast cancer survivors. ( Ballard-Barbash, R; Baumgartner, KB; Baumgartner, RN; Bernstein, L; Gilliland, F; Koprowski, C; McTiernan, A; Neuhouser, ML; Ulrich, CM; Wayne, S; Wiggins, C, 2008) |
| "Contrasting etiologic hypotheses about the role of endogenous sex steroids in breast cancer development among premenopausal women implicate ovarian androgen excess and progesterone deficiency, estrogen excess, estrogen and progesterone excess, and both an excess or lack of adrenal androgens (dehydroepiandrosterone [DHEA] or its sulfate [DHEAS]) as risk factors." | 3.73 | Serum sex steroids in premenopausal women and breast cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC). ( Amiano, P; Berrino, F; Biessy, C; Bingham, S; Boeing, H; Bueno de Mesquita, HB; Chang-Claude, J; Chirlaque, MD; Clavel-Chapelon, F; Critselis, E; Dossus, L; Ferrari, P; Fournier, A; Gonzalez, CA; Gurrea, AB; Kaaks, R; Key, T; Khaw, KT; Krogh, V; Lahmann, PH; Nagel, G; Norat, T; Olsen, A; Onland-Moret, NC; Overvad, K; Palli, D; Panico, S; Peeters, P; Quirós, JR; Riboli, E; Rinaldi, S; Roddam, A; Secreto, G; Slimani, N; Thiebaut, A; Tjønneland, A; Trichopoulos, D; Trichopoulou, A; Tumino, R; van Gils, CH; Vineis, P, 2005) |
| "The risk of breast cancer was associated with the highest versus lowest quartiles of estrone, OR: 2." | 3.72 | Postmenopausal breast cancer risk in relation to sex steroid hormones, prolactin and SHBG (Sweden). ( Agren, A; Berglund, G; Janzon, L; Johansson, R; Kaaks, R; Lenner, P; Manjer, J, 2003) |
| "Dehydroepiandrosterone sulfate (DHEA-S) comediates breast cancer progression via estrogen receptors (ERs) and androgen receptors (ARs)." | 3.72 | Estrogen and androgen receptors as comediators of breast cancer cell proliferation: providing a new therapeutic tool. ( Calhoun, K; Cheek, J; Muller, P; Pommier, RF; Toth-Fejel, S, 2004) |
| " In the present study we demonstrate that three major adrenal androgens, dehydroepiandrosterone, 5-androstene-3beta, 17beta-diol and 4-androstene 3,17-dione, all acquire an estradiol-like biological efficacy in aromatase transfected MCF7 breast cancer cells." | 3.71 | Aromatase overexpression enhances the stimulatory effects of adrenal androgens on MCF7 breast cancer cells. ( Andò, S; Bonofiglio, D; Carpino, A; Maggiolini, M; Marsico, S; Pezzi, V; Picard, D; Rago, V; Vivacqua, A, 2002) |
| "Dehydroepiandrosterone (DHEA) is a mitogen for estrogen-dependent MCF-7 breast cancer cells." | 3.71 | Dehydroepiandrosterone stimulates proliferation and gene expression in MCF-7 cells after conversion to estradiol. ( Klinga, K; Mayer, D; Morfin, R; Schmitt, M; Schnarr, B, 2001) |
| "The relationships between urinary 11-desoxy-17-oxo steroids (11-DOS), the ratio of 11-DOS to urinary 17-hydroxycorticosteroids (urinary discriminant ratio), plasma levels of the adrenal androgens dehydroepiandrosterone (DHA), DHA sulphate (DHAS), and 7 alpha-hydroxy DHA (7 alpha DHA), and tumour oestrogen receptor (ER) and progesterone receptor (PR) status were examined in pre, peri-, and postmenopausal women with breast cancer." | 3.69 | The relationship of urinary and plasma androgens to steroid receptors and menopausal status in breast cancer patients and their influence on survival. ( Holdaway, IM; Kay, RG; Mason, BH; Skinner, SJ, 1994) |
| " In the present study, we have examined the effect of dehydroepiandrosterone-3-O-methylthiophosphonate (DHA-3-MTP), pregnenolone-3-O-methylthiophosphonate (pregnenolone-3-MTP) and cholesterol-3-O-methylthiophosphonate (cholesterol-3-MTP) on the inhibition of oestrone sulphatase as well as DHA sulphatase activities in intact MCF-7 breast cancer cells and in placental microsomes." | 3.69 | Inhibition of steroid sulphatase activity by steroidal methylthiophosphonates: potential therapeutic agents in breast cancer. ( Howarth, NM; Potter, BV; Purohit, A; Reed, MJ, 1994) |
| "Epidemiological and experimental studies suggest that dehydroepiandrosterone (DHEA) exerts a protective effect against breast cancer." | 3.69 | Role of glucose-6-phosphate dehydrogenase inhibition in the antiproliferative effects of dehydroepiandrosterone on human breast cancer cells. ( Boccuzzi, G; Brignardello, E; Di Monaco, M; Gallo, M; Gatto, V; Leonardi, L; Pizzini, A, 1997) |
| "Serum dehydroepiandrosterone (DHEA), estrone (E1), and estradiol (E2) levels were prospectively measured in 47 breast cancer patients before and during tamoxifen therapy for 2 years." | 3.69 | Changes in serum estrogen levels in women during tamoxifen therapy. ( Fletcher, WS; Lum, SS; Pommier, RF; Woltering, EA, 1997) |
| "The effects of estradiol (E2), dihydrotestosterone (DHT) and dehydro-3-epiandrosterone (DHEA) on proliferation and progesterone receptor induction were studied in a breast cancer cell line (T47D) expressing estrogen, androgen, and progesterone receptors." | 3.68 | Effects of androgens on proliferation and progesterone receptor levels in T47D human breast cancer cells. ( Brentani, MM; Liberato, MH; Sonohara, S, 1993) |
| "Circulating preoperative levels of DHEA-S, androstenedione and SHBG were measured in 40 premenopausal and 49 postmenopausal breast cancer patients, and in 30 and 15 age-matched healthy controls, respectively." | 3.68 | Endocrine status in stage II vs. advanced premenopausal and postmenopausal breast cancer patients. ( Bhatavdekar, JM; Ghosh, N; Giri, DD; Karelia, NH; Patel, DD; Shah, NG; Suthar, TP; Trivedi, SN; Vora, HH, 1992) |
| "Dehydroepiandrosterone and dehydroepiandrosterone sulfate are steroids which may be associated with the development of breast cancer." | 3.68 | Relationship of prediagnostic serum levels of dehydroepiandrosterone and dehydroepiandrosterone sulfate to the risk of developing premenopausal breast cancer. ( Alberg, AJ; Bush, TL; Comstock, GW; Gordon, GB; Helzlsouer, KJ, 1992) |
| "The MCF-7 human breast cancer cell line responds to 5-androstene-3 beta,17 beta-diol, to dehydroepiandrosterone and to its 3 beta-sulfate stimulation in vitro by increased proliferation." | 3.68 | Biological effects of adrenal androgens on MCF-7 and BT-20 human breast cancer cells. ( Habrioux, G; Najid, A, 1990) |
| "The 24-h urinary excretion of dehydroepiandrosterone, androsterone and etiocholanolone was followed in healthy women (n = 50) and in women with benign-fibroadenoma (n = 32), microcysts (n = 32), macrocysts (n = 25) and malignant (n = 35) breast disease aged 35-50 years." | 3.68 | The urinary dehydroepiandrosterone, androsterone and etiocholanolone excretion of healthy women and women with benign and malignant breast disease. ( Agbaba, D; Ivanović, S; Konstantinović, I; Zivanov-Stakić, D, 1990) |
| "It has been suggested that dehydroepiandrosterone (DHEA) and its sulfate ester, dehydroepiandrosterone sulfate (DHEAS), have a protective effect against breast cancer." | 3.68 | Dehydroepiandrosterone sulfate and breast cancer risk. ( Barrett-Connor, E; Friedlander, NJ; Khaw, KT, 1990) |
| "The clinical and endocrine effects of low-dose aminoglutethimide without hydrocortisone in patients with advanced breast cancer were investigated." | 3.67 | Low-dose aminoglutethimide in treatment of advanced breast cancer. ( Bozek, T; Carr, L; Dowsett, M; Gazet, JC; Jeffcoate, SL; Kurkure, A; McKinna, JA; Smith, IE; Stuart-Harris, R, 1984) |
| "About one third of unselected postmenopausal women with advanced breast cancer respond to treatment with aminoglutethimide and hydrocortisone, but they all eventually relapse, and further progression of disease occurs." | 3.67 | Endocrine changes associated with relapse in advanced breast cancer patients on aminoglutethimide therapy. ( Dowsett, M; Harris, AL; Jeffcoate, SL; Smith, IE, 1984) |
| "The aim of this study is to report on Aminoglutethimide-induced hormonal modifications in advanced breast cancer." | 3.67 | Preliminary study of hormone determinations during aminoglutethimide therapy for advanced breast cancer. ( Díaz, L; Koliren, L; Loruso, A; Ramos, G; Scaglia, HE; Soto, E; Zylbersztein, C, 1984) |
| "Plasma concentrations of dehydroepiandrosterone (DHA), DHA-sulphate (DHAS) and 7 alpha hydroxy-DHA (7 alpha OHDHA) were measured and compared with tumor estrogen receptor (ER) status in 33 postmenopausal patients with breast cancer." | 3.67 | Estrogen receptor status, adrenal androgens and 7 alpha-hydroxydehydroepiandrosterone in breast cancer patients. ( Couch, RA; Holdaway, IM; Kay, RG; Mason, BH; Skinner, SJ, 1984) |
| "We investigated the role of androgens in premenopausal breast cancer by comparing serum testosterone, dihydrotestosterone, androstenedione, dehydroepiandrosterone sulfate, progesterone, sex-hormone-binding globulin-binding capacity, and urinary testosterone and androstanediol in 63 women with breast adenocarcinoma and 70 healthy controls of similar age." | 3.67 | Androgens and breast cancer in premenopausal women. ( Berrino, F; Cavalleri, A; Di Pietro, S; Fariselli, G; Pisani, P; Recchione, C; Secreto, G; Toniolo, P; Totis, A, 1989) |
| "Estrogen-sensitive human breast cancer cells (ZR-75-1) were incubated with the 3H-labeled adrenal C19-delta 5-steroids dehydroepiandrosterone (DHEA) and its fully estrogenic derivative, androst-5-ene-3 beta,17 beta-diol (delta 5-diol) for various time intervals." | 3.67 | Extensive esterification of adrenal C19-delta 5-sex steroids to long-chain fatty acids in the ZR-75-1 human breast cancer cell line. ( Bélanger, A; Labrie, F; Merand, Y; Poirier, D; Poulin, R; Thériault, C, 1989) |
| " Tamoxifen, an anti-estrogen, is used in the treatment of women with breast cancer in whom metastatic disease has been demonstrated." | 3.67 | Effects of tamoxifen on testosterone metabolism in postmenopausal women with breast cancer. ( Bird, CE; Clark, AF; Masters, V; Sterns, EE, 1985) |
| "The endocrine effects of aminoglutethimide 125 mg twice daily and hydrocortisone 20 mg twice daily were assessed in 45 postmenopausal women with advanced breast cancer." | 3.67 | Endocrine effects of low dose aminoglutethimide with hydrocortisone--an optimal hormone suppressive regimen. ( Cantwell, BM; Dowsett, M; Farndon, J; Harris, AL; Needham, G; Sainsbury, JR; Wilson, R, 1986) |
| "We have examined the effect of androst-5-ene-3 beta,17 beta-diol (delta 5-diol) and its precursors, dehydroepiandrosterone (DHEA) and dehydroepiandrosterone 3 beta-sulfate (DHEAS), on the growth of the estrogen-sensitive human breast cancer cell line, ZR-75-1." | 3.67 | Stimulation of cell proliferation and estrogenic response by adrenal C19-delta 5-steroids in the ZR-75-1 human breast cancer cell line. ( Labrie, F; Poulin, R, 1986) |
| "The possibility that medroxyprogesterone acetate (MPA) is clinically effective at least in part by its suppression of adrenal steroidogenesis and a resultant reduction of circulating oestrogen levels was investigated in 49 postmenopausal patients with advanced breast cancer." | 3.67 | The effects of low and high dose medroxyprogesterone acetate on sex steroids and sex hormone binding globulin in postmenopausal breast cancer patients. ( Dowsett, M; Jeffcoate, SL; Lal, A; Smith, IE, 1987) |
| "A short review is given about some of the data reported in the literature on dehydroepiandrosterone and its derivatives, delta 5-androstenediol (hermaphrodiol) and sexual steroid binding globulin (SHBG) in breast cancer patients." | 3.67 | [Dehydroepiandrosterone and other endocrine parameters in breast cancer]. ( Dässler, CG; Wilken, H, 1987) |
| "In North American women at low or high risk of developing breast cancer, as assessed by an epidemiologic questionnaire, the plasma concentration of dehydroepiandrosterone sulfate shows a statistically significant circannual variation." | 3.67 | [Blood levels of dehydroepiandrosterone sulfate (DHEA-S) and the risk of breast cancer]. ( Baulieu, EE; Cassanas, G; Gomes, P; Halberg, F; Haus, E; Hermida, R; Lakatua, D; Robel, P, 1988) |
| "A phase II study with cyproterone acetate (CPA) was done as the primary treatment in female breast cancer patients." | 3.67 | Clinical and endocrine effects of cyproterone acetate in postmenopausal patients with advanced breast cancer. ( de Vries, EG; Dikkeschei, LD; Mulder, NH; Sleijfer, DT; van der Ploeg, E; Willemse, PH, 1988) |
| "Reports of estrone (E1) and dehydroepiandrosterone (DHEA) sulfatase (sulfohydrolase) activities within many human breast cancers have prompted us to undertake the identification and partial characterization of these enzyme activities within MCF-7 human breast cancer cells." | 3.67 | The hydrolysis of estrone sulfate and dehydroepiandrosterone sulfate by MCF-7 human breast cancer cells. ( MacIndoe, JH, 1988) |
| "Hormonal changes induced by the pure antiandrogen flutamide were studied in three postmenopausal metastatic breast cancer patients." | 3.67 | Hormonal changes induced by the pure antiandrogen flutamide in postmenopausal women with advanced breast cancer. ( Ballerini, P; Fariselli, G; Recchione, C; Secreto, G; Zambetti, M, 1988) |
| "In order to determine whether human mammary tumours could contribute to cholesterol and dehydroepiandrosterone biosynthesis in breast cancer patients, incubations of homogenates of infiltrating ductal carcinoma were carried out separately with 2-14C acetate (patient, n = 6; 21-80 years) and 7n-3H pregnenolone (patient, n = 5, 36-74 years) as substrates." | 3.67 | Steroidogenic expression of delta 5-3 beta-hydroxy pathway of androgen biosynthesis by human breast carcinoma. ( Gunasegaram, R; Kottegoda, SR; Loganath, A; Peh, KL; Ratnam, SS; Thiagaraj, D, 1986) |
| "A group of 160 women with actively progressing metastatic breast cancer were treated with aminoglutethimide to induce medical adrenalectomy." | 3.66 | Aminoglutethimide in tamoxifen-resistant patients: The Melbourne Experience. ( Murray, RM; Pitt, P, 1982) |
| "Aminoglutethimide in combination with hydrocortisone provides an effective therapy in postmenopausal advanced breast cancer patients, with response rates of 37." | 3.66 | Endocrine and therapeutic effects of aminoglutethimide in premenopausal patients with breast cancer. ( Dowsett, M; Harris, AL; Jeffcoate, SL; McKinna, JA; Morgan, M; Smith, IE, 1982) |
| "Peripheral serum levels of cortisol, dehydroepiandrosterone (DHA), dehydroepiandrosterone sulphate (DHA-S), oestradiol-17 beta and total oestrone were measured in 17 postmenopausal breast cancer patients and on age-matched healthy controls." | 3.66 | Effects of tamoxifen on the serum levels of oestrogens and adrenocortical steroids in postmenopausal breast cancer patients. ( Carlström, K; Sköldefors, H; Theve, NO; Wallgren, A; Wilking, N, 1982) |
| "Cortisol and dehydroepiandrosterone sulphate (DHAS) were measured in saliva from postmenopausal women with primary breast cancer and a control group of comparable age." | 3.66 | Salivary cortisol and dehydroepiandrosterone sulphate levels in postmenopausal women with primary breast cancer. ( Blamey, RW; Campbell, FC; Griffiths, K; Holliday, HW; Read, GF; Wilson, DW, 1983) |
| "Ovarian and adrenal function were studied in premenopausal breast cancer patients before and at intervals during adjuvant therapy with cyclophosphamide, methotrexate, and 5-fluorouracil (CMF), CMF plus prednisone (CMFP), or CMFP plus tamoxifen (CMFPT)." | 3.66 | Effects of adjuvant chemohormonal therapy on the ovarian and adrenal function of breast cancer patients. ( Davis, TE; Rose, DP, 1980) |
| "Sixty-five patients with actively progressing advanced breast cancer were treated with aminoglutethimide, a drug which inhibits adrenal steroid synthesis and decreases peripheral conversion of androgens to oestrogens." | 3.66 | Medical adrenalectomy with aminoglutethimide in the management of advanced breast cancer. ( Jerums, G; Murray, RM; Pitt, P, 1981) |
| "The 24-hr mean plasma concentrations of dehydroisoandrosterone (DHA) and dehydroisoandrosterone sulfate were measured in 11 women with primary operable breast cancer, ages 31 to 78 years, and in 37 normal women, ages 21 to 75 years." | 3.66 | Abnormal 24-hr mean plasma concentrations of dehydroisoandrosterone and dehydroisoandrosterone sulfate in women with primary operable breast cancer. ( Fukushima, DK; Levin, J; Markham, M; Rosenfeld, RS; Strain, GW; Zumoff, B, 1981) |
| "The main fractions of 17-ketosteroids were estimated in 102 women with breast cancer." | 3.66 | Levels of principal 17-ketosteroid fractions in urine of breast cancer patients with or without malignant evolutive push. ( Frenkel, Z; Kiricuta, I; Munteanu, S, 1978) |
| " treatment with dehydroepiandrosterone, an adrenal steroid found in subnormal plasma concentrations in women predisposed to develop breast cancer, inhibits the formation of spontaneous mammary cancer in female C3H(Avy/a) mice." | 3.66 | Inhibition of spontaneous breast cancer formation in female C3H(Avy/a) mice by long-term treatment with dehydroepiandrosterone. ( Schwartz, AG, 1979) |
| "Measurement of the excretion of total 17-ketosteroids, androsterone, etiocholanolone, and dehydroepiandrosterone demonstrate in contrast to the well known age dependency of normal women in cases of both mastopathia and breast cancer the following results: 1." | 3.65 | Investigation of 17-ketosteriod excretion in mastopathia and premenopausal breast cancer. ( Eckhardt, S; Hindy, I; Prajda, N; Sellei, C; Tapolcsányi, L, 1975) |
| "Comparative investigations of the urinary excretion of different 17-ketosteroids in healthy women and patients suffering from mastopathia fibrocystica and/or mammary carcinomas had the following results: 1." | 3.65 | The excretion of 17-ketosteroids in patients suffering from mastopathia fibrocystica and mammary carcinomas. ( Görlich, M; Heise, E; Hindy, I; Pradja, N, 1975) |
| "Calusterone (7beta, 17alpha-dimethyltestosterone) is a 17-alkylated, orally active androgenic steroid used in the treatment of breast cancer." | 3.65 | The effect of 7beta, 17alpha-dimethyltestosterone (calusteron) on testosterone metabolism in women with advanced breast cancer. ( Bradlow, HL; Hellman, L; Levin, J; Zumoff, B, 1977) |
| "The levels of aetiocholanolone, androsterone, and 17-hydroxycorticosteroids were measured in women without known disease of the breast, in women with benign breast disease, and in women with primary and advanced breast cancer." | 3.65 | Benign and malignant breast disease in South Wales: a study of urinary steroids. ( Cameron, EH; Campbell, H; Forrest, AP; Gleave, E; Griffiths, K; Stewart, HJ, 1970) |
| " Our review determined that amongst published RCTs, no studies have aimed to assess for breast cancer recurrence; however among the studies observing for serious adverse effects of vaginal estrogen preparations, none have reported an increased incidence." | 3.01 | A systematic review of randomised clinical trials - The safety of vaginal hormones and selective estrogen receptor modulators for the treatment of genitourinary menopausal symptoms in breast cancer survivors. ( Hussain, I; Talaulikar, VS, 2023) |
| "Mechanisms by which DHEA may promote breast cancer relate to its effect in increasing circulating IGF-I, by inhibiting the suppressive effect of glucocorticoids, and by promoting retention of pre-adipocytes with aromatase activity." | 2.82 | Functions of dehydroepiandrosterone in relation to breast cancer. ( Chatterton, RT, 2022) |
| "Breast cancer is the most common malignancy in women with high mortality." | 2.72 | Breast Cancer: Targeting of Steroid Hormones in Cancerogenesis and Diagnostics. ( Kostecká, Z; Očenáš, P; Salayová, A; Valko-Rokytovská, M, 2021) |
| "Whether these changes influence breast cancer risk is currently unknown." | 2.71 | Diet and sex hormones in girls: findings from a randomized controlled clinical trial. ( Barton, BA; Buckman, DW; Chandler, DW; Dorgan, JF; Franklin, FA; Friedman, LA; Greenhut, SF; Hunsberger, SA; Kwiterovich, PO; Lasser, NL; Lauer, RM; McMahon, RP; Patterson, BH; Schatzkin, A; Snetselaar, LG; Stevens, VJ; Taylor, PR; Van Horn, L; Yanovski, JA, 2003) |
| "Fifty-nine patients with breast cancer and 10 with prostate cancer enrolled in an eight-week Mindfulness-Based Stress Reduction (MBSR) program that incorporated relaxation, meditation, gentle yoga, and daily home practice." | 2.71 | Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress and levels of cortisol, dehydroepiandrosterone sulfate (DHEAS) and melatonin in breast and prostate cancer outpatients. ( Carlson, LE; Goodey, E; Patel, KD; Speca, M, 2004) |
| "40), but not for MPA and estrone, indicating better adrenal suppression by higher MPA dosage and plasma levels." | 2.66 | Endocrine effects of medroxyprogesterone acetate: relation between plasma levels and suppression of adrenal steroids in patients with breast cancer. ( Doorenbos, H; Sleijfer, DT; Sluiter, WJ; van Veelen, H; Willemse, PH, 1985) |
| "Patients with breast cancer receiving antiestrogen therapy, specifically aromatase inhibitors, often suffer from vaginal dryness, itching, irritation, dyspareunia, and dysuria, collectively known as genitourinary syndrome of menopause (GSM)." | 2.61 | Managing Genitourinary Syndrome of Menopause in Breast Cancer Survivors Receiving Endocrine Therapy. ( Abraham, J; Kruse, ML; Sussman, TA; Thacker, HL, 2019) |
| "Some risk factors of breast cancer development, including obesity, have also been postulated to interact with steroid metabolising pathways." | 2.52 | The intracrinology of breast cancer. ( McNamara, KM; Sasano, H, 2015) |
| " Vaginal estrogen preparations with the lowest systemic absorption rate may be preferred in women with history of breast cancer and severe vaginal atrophy." | 2.48 | Management of vulvovaginal atrophy-related sexual dysfunction in postmenopausal women: an up-to-date review. ( Bradshaw, K; Carr, BR; Tan, O, 2012) |
| " However, it is unlikely that the general estrogen ablation achieved with aromatase inhibitors will be acceptable for the long-term use required for prevention." | 2.43 | Future perspectives of selective estrogen receptor modulators used alone and in combination with DHEA. ( Labrie, F, 2006) |
| "Late promotion of breast cancer in postmenopausal women may be stimulated by prolonged intake of DHEA, and the risk may be increased by the endocrine abnormality associated with pre-existing abdominal obesity." | 2.40 | Dietary supplements of dehydroepiandrosterone in relation to breast cancer risk. ( Stoll, BA, 1999) |
| "In some breast cancer cell lines in a low oestrogen milieu DHEA has an oestradiol-like effect, stimulating tumour growth, whereas in oestradiol abundance DHEA antagonises the growth-stimulating effect of oestradiol." | 2.39 | Physiological importance of dehydroepiandrosterone. ( Ebeling, P; Koivisto, VA, 1994) |
| "The low incidence of breast cancer in Japan disappears within 2 generations in migrant Japanese in the USA." | 2.38 | Human breast cancer: concerted role of diet, prolactin and adrenal C19-delta 5-steroids in tumorigenesis. ( Adams, JB, 1992) |
| " While this regimen effectively blocked adrenal function, it was complicated by a drug interaction in which aminoglutethimide accelerated the metabolism and reduced the bioavailability of dexamethasone." | 2.36 | Kinetic, hormonal and clinical studies with aminoglutethimide in breast cancer. ( Harvey, H; Kendall, J; Lipton, A; Ruby, EB; Samojlik, E; Santen, RJ; Wells, SA, 1977) |
| " Prasterone seems a safe and effective option to treat GSM in BCS receiving AIs." | 1.72 | Safety of prasterone in breast cancer survivors treated with aromatase inhibitors: the VIBRA pilot study. ( Alonso, I; Anglès-Acedo, S; Castelo-Branco, C; Castrejon, N; Cebrecos, I; Gómez, S; Matas, I; Mension, E; Ribera, L; Tortajada, M, 2022) |
| "Eighty-one patients with early-stage breast cancer (stages I-III) who had no prior exposure to chemotherapy and/or radiotherapy and were scheduled to receive anthracycline-based or taxane-based chemotherapy treatment with curative intent." | 1.51 | Prechemotherapy Levels of Plasma Dehydroepiandrosterone and Its Sulfated Form as Predictors of Cancer-Related Cognitive Impairment in Patients with Breast Cancer Receiving Chemotherapy. ( Bansal, S; Chan, A; Lau, AJ; Shariq Mujtaba, J; Shwe, M; Toh, YL; Yeo, A, 2019) |
| "Approximately 70% of breast cancers are diagnosed in postmenopausal women." | 1.40 | The role of hormones and aromatase inhibitors on breast tumor growth and general health in a postmenopausal mouse model. ( Arumugam, A; Lakshmanaswamy, R; Lissner, EA, 2014) |
| "Dehydroepiandrosterone (DHEA) has a protective role against cancer, however, the mechanism by which DHEA has this effect remains poorly understood." | 1.37 | Effects of dehydroepiandrosterone on proliferation, migration, and death of breast cancer cells. ( Contreras, PG; Dillon, JS; López-Marure, R, 2011) |
| "Dehydroepiandrosterone was most abundant in all samples, and exhibited a similar pattern as Adione and Aenediol." | 1.37 | Sex steroid hormones in pairs of tumor and serum from breast cancer patients and pathobiological role of androstene-3β, 17β-diol. ( Harada, N; Hayashi, S; Hirose, M; Honma, N; Horiguchi, S; Kuroi, K; Saji, S; Utsumi, T, 2011) |
| "The analysis included 317 cases of breast cancer diagnosed after blood collection and before June 1, 2003; for each case, two controls were matched on age, fasting status, time of day and month of blood collection, race/ethnicity, and timing of blood draw within the menstrual cycle." | 1.33 | The association of plasma DHEA and DHEA sulfate with breast cancer risk in predominantly premenopausal women. ( Barbieri, RL; Dowsett, M; Eliassen, AH; Folkerd, E; Hankinson, SE; Missmer, SA; Spiegelman, D; Tworoger, SS, 2006) |
| "Androstenediol levels were associated with risk (p-trend = 0." | 1.33 | Serum concentrations of estrogens, sex hormone-binding globulin, and androgens and risk of breast cancer in postmenopausal women. ( Adly, L; Fears, T; Hill, D; Hoover, RN; Mies, C; Schairer, C; Sherman, ME; Sturgeon, SR; Ziegler, RG, 2006) |
| "Cases of breast cancer under age 45 were identified using rapid ascertainment systems in Seattle/Puget Sound, Washington and control subjects were identified from the same area through random digit dialing methods." | 1.32 | Serum levels of sex hormones and breast cancer risk in premenopausal women: a case-control study (USA). ( Brinton, LA; Daling, J; Dorgan, JF; Malone, KE; Potischman, N; Schairer, C; Sturgeon, SR, 2004) |
| "Nor has the relation between breast cancer risk and postmenopausal progesterone levels been investigated." | 1.32 | Endogenous estrogen, androgen, and progesterone concentrations and breast cancer risk among postmenopausal women. ( Barbieri, RL; Eliassen, AH; Hankinson, SE; Missmer, SA, 2004) |
| "The estrogenic action of DHEAS on breast cancer cells was also measured by bioluminescence in a stably transfected human breast cancer MCF-7 cell line with a reporter gene that allowed expression of the firefly luciferase enzyme under the control of an estrogen regulatory element." | 1.31 | Conversion of dehydroepiandrosterone sulfate at physiological plasma concentration into estrogens in MCF-7 cells. ( Charles, L; Habrioux, G; Le Bail, JC; Lotfi, H; Pépin, D, 2002) |
| "Estrogen receptor (ER)-positive breast cancers initially respond well to estrogen ablation treatment but finally acquire refractoriness, the phenomenon that is a major clinical problem." | 1.31 | Gonadotropins stimulate growth of MCF-7 human breast cancer cells by promoting intracellular conversion of adrenal androgens to estrogens. ( Fujita, T; Kaiho, S; Kuwabara, K; Ogata, E; Oizumi, I; Okazaki, T; Tanaka, Y, 2000) |
| "Serum DHEA also has been related to breast cancer in postmenopausal women, but the relationship of ADIOL to risk has not been evaluated previously." | 1.30 | Relationship of serum dehydroepiandrosterone (DHEA), DHEA sulfate, and 5-androstene-3 beta, 17 beta-diol to risk of breast cancer in postmenopausal women. ( Chang, L; Dorgan, JF; Falk, RT; Franz, C; Kahle, L; Longcope, C; Miller, R; Stanczyk, FZ; Stephenson, HE, 1997) |
| "97 women with confirmed incident breast cancer and 244 randomly selected controls; all women were white, 65 years of age or older, and were not receiving estrogen." | 1.30 | Elevated serum estradiol and testosterone concentrations are associated with a high risk for breast cancer. Study of Osteoporotic Fractures Research Group. ( Browner, W; Cauley, JA; Cummings, SR; Kuller, LH; Lucas, FL; Stone, K, 1999) |
| "Dehydroepiandrosterone (DHEA) has been shown to affect the growth of mammary carcinomas both in vitro and in vivo." | 1.29 | Dehydroepiandrosterone concentration in breast cancer tissue is related to its plasma gradient across the mammary gland. ( Boccuzzi, G; Brignardello, E; Cassoni, P; Di Monaco, M; Massobrio, M; Migliardi, M; Pizzini, A, 1995) |
| "The concentration of Adione in breast cancer tissue is much lower than the reported Km of the aromatase system for Adione." | 1.28 | Tissue androgens and the endocrine autonomy of breast cancer. ( Blankenstein, MA; Daroszewski, J; Donker, GH; Maitimu-Smeele, I; Milewicz, A; Thijssen, JH, 1992) |
| "Dehydroepiandrosterone was also measured in the 800 g fraction of 45 tumors and its concentration, which was some 10-fold higher than ADIOL and significantly correlated with that steroid, was again independent of menopausal status." | 1.28 | Estrogen receptor and C19-5-ene-steroid concentrations in the nuclear fraction from human breast carcinoma tissue. ( Adams, JB; Seymour-Munn, K, 1992) |
| "The implications for breast cancer risk are discussed." | 1.28 | Hormone levels in vegetarian and nonvegetarian teenage girls: potential implications for breast cancer risk. ( Chatterton, RT; Grant, MD; Langenberg, P; Marvin, J; Persky, VW; Van Horn, LV, 1992) |
| "Reports that MCF-7 human breast cancer cells can transform both estrone (E1)1 to estradiol (E2) and dehydroepiandrosterone (DHEA) to the estrogenic steroid 5-androstenediol (AED), have prompted us to investigate the 17-ketosteroid reductase activities (17-KSR's) which mediate these potentially important reactions." | 1.28 | Dehydroepiandrosterone and estrone 17-ketosteroid reductases in MCF-7 human breast cancer cells. ( Hinkhouse, M; MacIndoe, JH; Woods, G, 1990) |
| "Aminoglutethimide (Ag) has been used in different dosages with and without combined treatment with glucocorticoids for the suppression of peripheral plasma levels of steroidal hormones." | 1.27 | Endocrine effects of aminoglutethimide plus hydrocortisone versus effects of high dose of hydrocortisone alone in postmenopausal metastatic breast cancer. ( Alexieva-Figusch, J; de Jong, FH; Klign, JG; Lamberts, WJ; van Gilse, HA, 1987) |
| "Ketoconazole was poorly tolerated due to gastrointestinal toxicity." | 1.27 | High dose ketoconazole: endocrine and therapeutic effects in postmenopausal breast cancer. ( Cantwell, BM; Dowsett, M; Harris, AL, 1988) |
| "The ability of human breast carcinomas to convert pregnenolone to progesterone and dehydroepiandrosterone to delta 4-androstene-3,17-dione (delta 4) was investigated as a potential aid for prognosis, and the following observations were recorded." | 1.26 | Hormone synthesis by primary breast carcinomas and prognosis in human breast cancer. ( Deshpande, N; Di Martino, L; Mitchell, I; Tarquini, A, 1980) |
| "Enzymic Synthesis of Steroid Sulfate by Mammary Cancer and Its Clinical Implications." | 1.26 | Dehydroepiandrosterone sulfotransferase as a possible shunt for the control of steroid metabolism in human mammary carcinoma. ( Adams, JB; Chandra, DP, 1977) |
| "In Japanese but not Caucasian breast cancer patients, the estradiol decreased." | 1.26 | Diet and endocrine-related cancer. ( Chan, P; Cohen, L; Hill, P; Kuno, K; Wynder, E, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 200 (60.61) | 18.7374 |
| 1990's | 55 (16.67) | 18.2507 |
| 2000's | 44 (13.33) | 29.6817 |
| 2010's | 23 (6.97) | 24.3611 |
| 2020's | 8 (2.42) | 2.80 |
| Authors | Studies |
|---|---|
| Chatterton, RT | 3 |
| Ihenacho, U | 1 |
| Sriprasert, I | 1 |
| Mack, WJ | 1 |
| Hamilton, AS | 1 |
| Unger, JB | 1 |
| Press, MF | 1 |
| Wu, AH | 1 |
| Mension, E | 1 |
| Alonso, I | 1 |
| Cebrecos, I | 1 |
| Castrejon, N | 1 |
| Tortajada, M | 1 |
| Matas, I | 1 |
| Gómez, S | 1 |
| Ribera, L | 1 |
| Anglès-Acedo, S | 1 |
| Castelo-Branco, C | 1 |
| Toh, YL | 2 |
| Tan, CJ | 1 |
| Yap, NY | 1 |
| Parajuli, R | 1 |
| Lau, AJ | 2 |
| Chan, A | 2 |
| Salvatore, S | 3 |
| Benini, V | 3 |
| Ruffolo, AF | 3 |
| Degliuomini, RS | 3 |
| Redaelli, A | 3 |
| Casiraghi, A | 3 |
| Candiani, M | 3 |
| Hussain, I | 1 |
| Talaulikar, VS | 1 |
| Valko-Rokytovská, M | 1 |
| Očenáš, P | 1 |
| Salayová, A | 1 |
| Kostecká, Z | 1 |
| Pérez-López, FR | 1 |
| Phillips, N | 1 |
| Vieira-Baptista, P | 1 |
| Cohen-Sacher, B | 1 |
| Fialho, SCAV | 1 |
| Stockdale, CK | 1 |
| Barton, DL | 1 |
| Shuster, LT | 1 |
| Dockter, T | 1 |
| Atherton, PJ | 1 |
| Thielen, J | 1 |
| Birrell, SN | 1 |
| Sood, R | 1 |
| Griffin, P | 1 |
| Terstriep, SA | 1 |
| Mattar, B | 1 |
| Lafky, JM | 1 |
| Loprinzi, CL | 1 |
| Pietri, E | 1 |
| Massa, I | 1 |
| Bravaccini, S | 1 |
| Ravaioli, S | 1 |
| Tumedei, MM | 1 |
| Petracci, E | 1 |
| Donati, C | 1 |
| Schirone, A | 1 |
| Piacentini, F | 1 |
| Gianni, L | 1 |
| Nicolini, M | 1 |
| Campadelli, E | 1 |
| Gennari, A | 1 |
| Saba, A | 1 |
| Campi, B | 1 |
| Valmorri, L | 1 |
| Andreis, D | 1 |
| Fabbri, F | 1 |
| Amadori, D | 1 |
| Rocca, A | 1 |
| Shariq Mujtaba, J | 1 |
| Bansal, S | 1 |
| Yeo, A | 1 |
| Shwe, M | 1 |
| Sussman, TA | 1 |
| Kruse, ML | 1 |
| Thacker, HL | 1 |
| Abraham, J | 1 |
| Cabeza, M | 1 |
| Heuze, Y | 1 |
| Sánchez, A | 1 |
| Garrido, M | 1 |
| Bratoeff, E | 1 |
| McNamara, KM | 1 |
| Sasano, H | 2 |
| Labrie, F | 13 |
| Arumugam, A | 1 |
| Lissner, EA | 1 |
| Lakshmanaswamy, R | 1 |
| Li, L | 1 |
| Fath, MA | 1 |
| Scarbrough, PM | 1 |
| Watson, WH | 1 |
| Spitz, DR | 1 |
| Xu, D | 1 |
| Lin, SX | 4 |
| López-Marure, R | 2 |
| Zapata-Gómez, E | 1 |
| Rocha-Zavaleta, L | 1 |
| Aguilar, MC | 1 |
| Espinosa Castilla, M | 1 |
| Meléndez Zajgla, J | 1 |
| Meraz-Cruz, N | 1 |
| Huesca-Gómez, C | 1 |
| Gamboa-Ávila, R | 1 |
| Gómez-González, EO | 1 |
| Dumas, NA | 1 |
| He, D | 2 |
| Frost, AR | 2 |
| Falany, CN | 2 |
| Thomas, JL | 2 |
| Bucholtz, KM | 2 |
| Sun, J | 2 |
| Mack, VL | 2 |
| Kacsoh, B | 1 |
| Wayne, S | 1 |
| Neuhouser, ML | 1 |
| Ulrich, CM | 2 |
| Koprowski, C | 1 |
| Wiggins, C | 1 |
| Baumgartner, KB | 1 |
| Bernstein, L | 4 |
| Baumgartner, RN | 1 |
| Gilliland, F | 1 |
| McTiernan, A | 2 |
| Ballard-Barbash, R | 2 |
| Howgate, DJ | 1 |
| Gamie, Z | 1 |
| Panteliadis, P | 1 |
| Bhalla, A | 1 |
| Mantalaris, A | 1 |
| Tsiridis, E | 1 |
| Terrell, JR | 1 |
| Pettersson, H | 1 |
| Lundqvist, J | 1 |
| Norlin, M | 1 |
| Guay, A | 1 |
| Traish, A | 1 |
| Dimitrakakis, C | 1 |
| Zava, D | 2 |
| Marinopoulos, S | 1 |
| Tsigginou, A | 1 |
| Antsaklis, A | 1 |
| Glaser, R | 1 |
| Contreras, PG | 1 |
| Dillon, JS | 1 |
| Shi, P | 1 |
| Zhang, Y | 1 |
| Tong, X | 1 |
| Yang, Y | 1 |
| Shao, Z | 1 |
| Parker, NP | 1 |
| Habe-Evans, M | 1 |
| Bryk, M | 1 |
| Scholtens, DM | 1 |
| Khan, SA | 1 |
| Honma, N | 1 |
| Saji, S | 1 |
| Hirose, M | 1 |
| Horiguchi, S | 1 |
| Kuroi, K | 1 |
| Hayashi, S | 1 |
| Utsumi, T | 1 |
| Harada, N | 1 |
| Simon, JA | 1 |
| Tan, O | 1 |
| Bradshaw, K | 1 |
| Carr, BR | 1 |
| Sandra, N | 1 |
| Ester, P | 1 |
| Marie-Agnès, P | 1 |
| Robert, M | 1 |
| Olivier, H | 1 |
| Perzyło, K | 1 |
| Kulik-Rechberger, B | 1 |
| Gałczyński, K | 1 |
| Rechberger, T | 1 |
| Maggiolini, M | 3 |
| Bonofiglio, D | 2 |
| Pezzi, V | 2 |
| Carpino, A | 2 |
| Marsico, S | 2 |
| Rago, V | 2 |
| Vivacqua, A | 1 |
| Picard, D | 3 |
| Andò, S | 3 |
| Shimizu, M | 1 |
| Ohta, K | 1 |
| Matsumoto, Y | 1 |
| Fukuoka, M | 1 |
| Ohno, Y | 1 |
| Ozawa, S | 1 |
| Le Bail, JC | 2 |
| Lotfi, H | 1 |
| Charles, L | 1 |
| Pépin, D | 1 |
| Habrioux, G | 3 |
| Dorgan, JF | 6 |
| Hunsberger, SA | 1 |
| McMahon, RP | 1 |
| Kwiterovich, PO | 1 |
| Lauer, RM | 1 |
| Van Horn, L | 1 |
| Lasser, NL | 1 |
| Stevens, VJ | 1 |
| Friedman, LA | 1 |
| Yanovski, JA | 1 |
| Greenhut, SF | 1 |
| Chandler, DW | 2 |
| Franklin, FA | 1 |
| Barton, BA | 1 |
| Buckman, DW | 1 |
| Snetselaar, LG | 1 |
| Patterson, BH | 1 |
| Schatzkin, A | 2 |
| Taylor, PR | 3 |
| Belaisch, J | 1 |
| Luu-The, V | 4 |
| Labrie, C | 5 |
| Bélanger, A | 7 |
| Simard, J | 5 |
| Pelletier, G | 3 |
| BULBROOK, RD | 23 |
| THOMAS, BS | 6 |
| BROOKSBANK, BW | 1 |
| LAMB, EJ | 1 |
| DIGNAM, WJ | 1 |
| PION, RJ | 1 |
| SIMMER, HH | 1 |
| KHATTAB, AA | 1 |
| BARON, DN | 1 |
| DESHPANDE, N | 13 |
| ELLIS, FG | 1 |
| HAYWARD, JL | 12 |
| PARKER, J | 1 |
| WANG, DY | 17 |
| PIPINO, G | 1 |
| ADAMS, JB | 12 |
| SCHUBERT, K | 6 |
| BACIGALUPO, G | 6 |
| MARMORSTON, J | 1 |
| CROWLEY, LG | 1 |
| MYERS, SM | 1 |
| STERN, E | 1 |
| HOPKINS, CE | 1 |
| FRANKENBERG, G | 3 |
| DENEVE, L | 1 |
| VERMEULEN, A | 1 |
| Manjer, J | 1 |
| Johansson, R | 1 |
| Berglund, G | 1 |
| Janzon, L | 1 |
| Kaaks, R | 2 |
| Agren, A | 1 |
| Lenner, P | 1 |
| Toth-Fejel, S | 1 |
| Cheek, J | 1 |
| Calhoun, K | 1 |
| Muller, P | 1 |
| Pommier, RF | 4 |
| Carlson, LE | 1 |
| Speca, M | 1 |
| Patel, KD | 1 |
| Goodey, E | 1 |
| Sturgeon, SR | 2 |
| Potischman, N | 1 |
| Malone, KE | 1 |
| Daling, J | 1 |
| Schairer, C | 2 |
| Brinton, LA | 1 |
| Schernhammer, ES | 1 |
| Rosner, B | 1 |
| Willett, WC | 2 |
| Laden, F | 1 |
| Colditz, GA | 2 |
| Hankinson, SE | 4 |
| Page, JH | 1 |
| Rifai, N | 1 |
| Barbieri, RL | 3 |
| von Allmen, G | 1 |
| Escher, H | 1 |
| Wasem, Ch | 1 |
| Fischer, J | 1 |
| Onland-Moret, NC | 2 |
| Peeters, PH | 1 |
| van der Schouw, YT | 1 |
| Grobbee, DE | 1 |
| van Gils, CH | 2 |
| Missmer, SA | 2 |
| Eliassen, AH | 2 |
| Bradlow, HL | 3 |
| Sepkovic, DW | 2 |
| Howard, JM | 1 |
| Berrino, F | 2 |
| Key, T | 2 |
| Rinaldi, S | 1 |
| Dossus, L | 1 |
| Biessy, C | 1 |
| Secreto, G | 3 |
| Amiano, P | 1 |
| Bingham, S | 1 |
| Boeing, H | 1 |
| Bueno de Mesquita, HB | 1 |
| Chang-Claude, J | 1 |
| Clavel-Chapelon, F | 1 |
| Fournier, A | 1 |
| Gonzalez, CA | 1 |
| Gurrea, AB | 1 |
| Critselis, E | 1 |
| Khaw, KT | 2 |
| Krogh, V | 1 |
| Lahmann, PH | 1 |
| Nagel, G | 1 |
| Olsen, A | 1 |
| Overvad, K | 1 |
| Palli, D | 1 |
| Panico, S | 1 |
| Peeters, P | 1 |
| Quirós, JR | 1 |
| Roddam, A | 1 |
| Thiebaut, A | 1 |
| Tjønneland, A | 1 |
| Chirlaque, MD | 1 |
| Trichopoulou, A | 1 |
| Trichopoulos, D | 1 |
| Tumino, R | 1 |
| Vineis, P | 1 |
| Norat, T | 1 |
| Ferrari, P | 1 |
| Slimani, N | 1 |
| Riboli, E | 1 |
| Johnson, CE | 1 |
| Berman, JR | 1 |
| Shilkaitis, A | 1 |
| Green, A | 1 |
| Punj, V | 1 |
| Steele, V | 1 |
| Lubet, R | 1 |
| Christov, K | 1 |
| Tworoger, SS | 2 |
| Spiegelman, D | 1 |
| Folkerd, E | 1 |
| Dowsett, M | 13 |
| Adly, L | 1 |
| Hill, D | 1 |
| Sherman, ME | 1 |
| Fears, T | 1 |
| Mies, C | 1 |
| Ziegler, RG | 1 |
| Hoover, RN | 2 |
| Dumas, N | 1 |
| Falany, JL | 1 |
| Abrahamson, PE | 1 |
| Aiello, EJ | 1 |
| Gilliland, FD | 1 |
| Stanczyk, FZ | 4 |
| Baumgartner, R | 1 |
| Baumgartner, K | 1 |
| Sorensen, B | 1 |
| Spiegel, D | 1 |
| Giese-Davis, J | 1 |
| Taylor, CB | 1 |
| Kraemer, H | 1 |
| Raven, PW | 1 |
| Hinson, JP | 1 |
| Miki, Y | 1 |
| Nahleh, Z | 1 |
| Stuart-Harris, R | 2 |
| Bozek, T | 1 |
| McKinna, JA | 2 |
| Gazet, JC | 3 |
| Jeffcoate, SL | 7 |
| Kurkure, A | 1 |
| Carr, L | 1 |
| Smith, IE | 10 |
| Coombes, RC | 2 |
| Chilvers, C | 1 |
| Ford, HT | 1 |
| Bettelheim, R | 1 |
| Gordon, C | 1 |
| Powles, TJ | 2 |
| Abul-Hajj, YJ | 4 |
| Murray, RM | 2 |
| Pitt, P | 3 |
| England, PC | 1 |
| Sellwood, RA | 1 |
| Knyba, RE | 2 |
| Irvine, JD | 1 |
| Kent, S | 1 |
| Harris, AL | 8 |
| Morgan, M | 1 |
| Wilking, N | 3 |
| Carlström, K | 3 |
| Sköldefors, H | 2 |
| Theve, NO | 2 |
| Wallgren, A | 1 |
| Miller, WR | 6 |
| Humeniuk, V | 1 |
| Forrest, AP | 12 |
| Riad-Fahmy, D | 1 |
| Read, GF | 2 |
| Walker, RF | 1 |
| Griffiths, K | 11 |
| Fehér, T | 2 |
| Bodrogi, L | 2 |
| Vallent, K | 2 |
| Ribai, Z | 2 |
| Apter, D | 1 |
| Vihko, R | 1 |
| Wilson, DW | 1 |
| Campbell, FC | 1 |
| Holliday, HW | 1 |
| Blamey, RW | 1 |
| Halberg, F | 3 |
| Imayoshi, E | 1 |
| Fukuda, K | 1 |
| Teramoto, S | 1 |
| Kamata, S | 1 |
| Sakaguchi, I | 1 |
| Hirai, R | 1 |
| Takashima, S | 1 |
| Bonney, RC | 1 |
| Scanlon, MJ | 1 |
| Reed, MJ | 5 |
| Jones, DL | 3 |
| Beranek, PA | 1 |
| James, VH | 4 |
| Jeffcoate, S | 1 |
| Scaglia, HE | 1 |
| Koliren, L | 1 |
| Loruso, A | 1 |
| Zylbersztein, C | 1 |
| Ramos, G | 1 |
| Díaz, L | 1 |
| Soto, E | 1 |
| Skinner, SJ | 4 |
| Holdaway, IM | 2 |
| Mason, BH | 2 |
| Couch, RA | 3 |
| Kay, RG | 3 |
| Marković, L | 1 |
| Ivanović, S | 2 |
| Konstantinović, I | 2 |
| Ikić, D | 1 |
| Micić, J | 1 |
| Stakić, B | 1 |
| Döberl, A | 1 |
| Pousette, A | 2 |
| Rannevik, G | 2 |
| Blackburn, AM | 1 |
| Kwa, HG | 2 |
| Hoare, SA | 2 |
| Rubens, RD | 3 |
| Stuart-Harris, RC | 1 |
| Kim, MH | 1 |
| Chang, FE | 1 |
| van Veelen, H | 3 |
| Willemse, PH | 5 |
| Sleijfer, DT | 4 |
| Pratt, JJ | 1 |
| Sluiter, WJ | 2 |
| Doorenbos, H | 2 |
| Thambyah, S | 1 |
| Dobbs, RJ | 1 |
| Jordan, SM | 1 |
| Mason, B | 1 |
| Mason, RC | 1 |
| Chetty, U | 1 |
| Hawkins, RA | 1 |
| Nelson, W | 1 |
| Bingham, C | 1 |
| Haus, E | 2 |
| Lakatua, DJ | 1 |
| Kawasaki, T | 1 |
| Samojlik, E | 5 |
| Santen, RJ | 5 |
| Archibald, L | 2 |
| Seymour-Munn, K | 2 |
| Di Martino, L | 2 |
| Tarquini, A | 2 |
| Mitchell, I | 2 |
| Rose, DP | 3 |
| Davis, TE | 2 |
| Jerums, G | 1 |
| Siiteri, PK | 1 |
| Zumoff, B | 2 |
| Levin, J | 2 |
| Rosenfeld, RS | 1 |
| Markham, M | 1 |
| Strain, GW | 1 |
| Fukushima, DK | 1 |
| Adams, J | 1 |
| Garcia, M | 1 |
| Rochefort, H | 1 |
| Worgul, TJ | 1 |
| Wells, SA | 3 |
| Boffard, K | 1 |
| Clark, GM | 1 |
| Irvine, JB | 1 |
| Edery, M | 1 |
| Carreau, S | 1 |
| Simon, MJ | 1 |
| Drosdowsky, MA | 1 |
| Lai, LC | 2 |
| Purohit, A | 3 |
| Duncan, LJ | 1 |
| Singh, A | 1 |
| Roberts, CJ | 1 |
| Williams, GJ | 1 |
| Potter, BV | 2 |
| Brignardello, E | 3 |
| Cassoni, P | 2 |
| Migliardi, M | 2 |
| Pizzini, A | 2 |
| Di Monaco, M | 2 |
| Boccuzzi, G | 3 |
| Massobrio, M | 2 |
| Woltering, EA | 3 |
| Fletcher, WS | 4 |
| Ebeling, P | 1 |
| Koivisto, VA | 1 |
| Dikkeschei, LD | 3 |
| Wolthers, BG | 1 |
| Menzaghi, C | 1 |
| Revelli, A | 1 |
| Cenderelli, G | 1 |
| Reichman, ME | 1 |
| Judd, JT | 2 |
| Brown, C | 1 |
| Longcope, C | 3 |
| Campbell, WS | 2 |
| Franz, C | 2 |
| Kahle, L | 2 |
| Howarth, NM | 1 |
| Roy, R | 1 |
| Ross, RK | 2 |
| Liberato, MH | 1 |
| Sonohara, S | 1 |
| Brentani, MM | 1 |
| Maggino, T | 2 |
| Marcadella, CB | 2 |
| Romagnolo, C | 2 |
| O'Shaughnessy, JA | 1 |
| Lu, LJ | 1 |
| Anderson, KE | 1 |
| Grady, JJ | 1 |
| Nagamani, M | 1 |
| Odin, VI | 1 |
| Tsyrlina, EV | 1 |
| Gamaiunova, VB | 1 |
| Bershteĭn, LM | 1 |
| Gatto, V | 1 |
| Leonardi, L | 1 |
| Gallo, M | 1 |
| Kelloff, GJ | 1 |
| Boone, CW | 1 |
| Crowell, JA | 1 |
| Nayfield, SG | 1 |
| Hawk, ET | 1 |
| Steele, VE | 1 |
| Lubet, RA | 1 |
| Sigman, CC | 1 |
| Stephenson, HE | 2 |
| Chang, L | 1 |
| Miller, R | 1 |
| Falk, RT | 1 |
| Lum, SS | 1 |
| McNeil, C | 1 |
| Holzman, D | 1 |
| Hornsby, PJ | 1 |
| Couillard, S | 1 |
| Candas, B | 1 |
| Pouliot, F | 1 |
| Haines, GK | 1 |
| Marre-Fournier, F | 1 |
| Nicolas, JC | 1 |
| Cauley, JA | 1 |
| Lucas, FL | 1 |
| Kuller, LH | 1 |
| Stone, K | 1 |
| Browner, W | 1 |
| Cummings, SR | 1 |
| Chobanyan, NS | 1 |
| Donzé, O | 1 |
| Jeannin, E | 1 |
| Stoll, BA | 1 |
| El-Alfy, M | 1 |
| Tanaka, Y | 1 |
| Kuwabara, K | 1 |
| Okazaki, T | 1 |
| Fujita, T | 1 |
| Oizumi, I | 1 |
| Kaiho, S | 1 |
| Ogata, E | 1 |
| Schmitt, M | 1 |
| Klinga, K | 1 |
| Schnarr, B | 1 |
| Morfin, R | 1 |
| Mayer, D | 1 |
| Baer, DJ | 1 |
| Albert, PS | 1 |
| Brown, ED | 1 |
| Corle, DK | 1 |
| Hartman, TJ | 1 |
| Tejpar, AA | 1 |
| Clevidence, BA | 1 |
| Giffen, CA | 1 |
| Appleby, P | 1 |
| Barnes, I | 1 |
| Reeves, G | 1 |
| Ciolino, HP | 1 |
| MacDonald, CJ | 1 |
| Yeh, GC | 1 |
| Tobler, CJ | 1 |
| Doouss, TW | 7 |
| Hindy, I | 2 |
| Prajda, N | 1 |
| Tapolcsányi, L | 1 |
| Sellei, C | 1 |
| Eckhardt, S | 1 |
| Görlich, M | 2 |
| Heise, E | 2 |
| Hill, P | 3 |
| Wynder, EL | 3 |
| Helman, P | 2 |
| Hickman, R | 2 |
| Rona, G | 2 |
| Pradja, N | 1 |
| Kuno, K | 2 |
| Poortman, J | 7 |
| Carson, P | 4 |
| Kirby, P | 1 |
| Symes, EK | 1 |
| Calabresi, E | 1 |
| De Giuli, G | 1 |
| Becciolini, A | 1 |
| Giannotti, P | 1 |
| Lombardi, G | 1 |
| Serio, M | 1 |
| Bates, T | 2 |
| Goodwin, PR | 1 |
| Knight, RK | 2 |
| Chandra, DP | 2 |
| Li, K | 2 |
| Foo, T | 2 |
| McDonald, D | 2 |
| O'Higgins, NJ | 1 |
| Stauber, P | 1 |
| Thiel, A | 1 |
| Crowley, JJ | 1 |
| Milbrath, JR | 1 |
| Chan, P | 1 |
| Cohen, L | 1 |
| Wynder, E | 1 |
| Borkowski, A | 1 |
| L'hermite, M | 1 |
| Dor, P | 1 |
| Longeval, E | 1 |
| Rozencweig, M | 1 |
| Muquardt, C | 1 |
| Van Cauter, E | 1 |
| Hellman, L | 1 |
| Lachelin, GC | 1 |
| Yen, SC | 1 |
| Alksne, JF | 1 |
| Maynard, PV | 2 |
| Pike, AW | 1 |
| Weston, A | 1 |
| Papatestas, AE | 1 |
| Mulvihill, M | 1 |
| Genkins, G | 1 |
| Kornfeld, P | 1 |
| Aufses, AH | 1 |
| Bird, M | 1 |
| Basu, PK | 1 |
| Shields, R | 1 |
| Clarke, C | 1 |
| Kiricuta, I | 1 |
| Frenkel, Z | 1 |
| Munteanu, S | 1 |
| Schwartz, AG | 1 |
| Iverson, R | 2 |
| Kiang, DT | 2 |
| Stancáková, A | 1 |
| Klimesová, Z | 1 |
| Hill, PB | 1 |
| Moore, JW | 2 |
| Tong, D | 2 |
| Prenen, JA | 1 |
| Schwarz, F | 4 |
| Thijssen, JH | 8 |
| Godefroi, VC | 1 |
| Locke, ER | 1 |
| Singh, DV | 1 |
| Brooks, SC | 2 |
| Vroegindewey-Jie, D | 1 |
| Dao, TL | 6 |
| Oertel, GW | 2 |
| Benes, P | 1 |
| Hoffmann, G | 2 |
| Schuy, E | 1 |
| Lipton, A | 1 |
| Harvey, H | 1 |
| Ruby, EB | 1 |
| Kendall, J | 2 |
| Runić, S | 1 |
| Gupta, C | 1 |
| Rudy, EB | 1 |
| Nagasawa, H | 1 |
| Nishida, S | 1 |
| Matsumura, S | 1 |
| Horino, M | 1 |
| Matsuki, M | 1 |
| Oyama, H | 1 |
| Tenku, A | 1 |
| Kakita, K | 1 |
| Tanaka, H | 1 |
| Omukai, Y | 1 |
| Blankenstein, MA | 1 |
| Maitimu-Smeele, I | 1 |
| Donker, GH | 1 |
| Daroszewski, J | 1 |
| Milewicz, A | 1 |
| Bhatavdekar, JM | 1 |
| Patel, DD | 1 |
| Shah, NG | 1 |
| Giri, DD | 1 |
| Vora, HH | 1 |
| Karelia, NH | 1 |
| Trivedi, SN | 1 |
| Ghosh, N | 1 |
| Suthar, TP | 1 |
| Helzlsouer, KJ | 2 |
| Gordon, GB | 2 |
| Alberg, AJ | 1 |
| Bush, TL | 2 |
| Comstock, GW | 2 |
| Persky, VW | 1 |
| Van Horn, LV | 1 |
| Grant, MD | 1 |
| Langenberg, P | 1 |
| Marvin, J | 1 |
| Mancini, A | 1 |
| Di Pietro, C | 1 |
| De Marinis, L | 1 |
| Rossi, S | 1 |
| Lombardi, CP | 1 |
| Bellantone, R | 1 |
| Liberale, I | 1 |
| Menini, E | 1 |
| Crucitti, F | 1 |
| MacIndoe, JH | 2 |
| Hinkhouse, M | 1 |
| Woods, G | 1 |
| Pike, MC | 1 |
| Brown, JB | 2 |
| Henderson, BE | 1 |
| Najid, A | 2 |
| Miller, SR | 1 |
| Castagnetta, L | 1 |
| Granata, OM | 1 |
| Brignone, G | 1 |
| Blasi, L | 1 |
| Arcuri, F | 1 |
| Mesiti, M | 1 |
| D'Aquino, A | 1 |
| Preitano, W | 1 |
| Tjabbes, T | 1 |
| Agbaba, D | 1 |
| Zivanov-Stakić, D | 1 |
| Basilio, E | 1 |
| Prats, M | 1 |
| Rivera, F | 1 |
| Barrett-Connor, E | 1 |
| Friedlander, NJ | 1 |
| Bruning, PF | 1 |
| Bonfrèr, JM | 1 |
| Wildiers, J | 1 |
| Jassem, J | 1 |
| Beex, LV | 1 |
| Schornagel, J | 1 |
| Nooijen, WJ | 1 |
| Toniolo, P | 1 |
| Pisani, P | 1 |
| Recchione, C | 2 |
| Cavalleri, A | 1 |
| Fariselli, G | 2 |
| Totis, A | 1 |
| Di Pietro, S | 1 |
| Poulin, R | 2 |
| Poirier, D | 1 |
| Merand, Y | 1 |
| Thériault, C | 1 |
| Hill, M | 1 |
| Cantwell, BM | 3 |
| Bird, CE | 2 |
| Masters, V | 1 |
| Sterns, EE | 1 |
| Clark, AF | 2 |
| van Landeghem, AA | 2 |
| Dixon, JM | 1 |
| Drife, JO | 1 |
| Goss, PE | 1 |
| Hutchison, G | 1 |
| Brodie, AM | 1 |
| Sainsbury, JR | 1 |
| Needham, G | 1 |
| Farndon, J | 1 |
| Wilson, R | 1 |
| Musey, VC | 1 |
| Collins, DC | 1 |
| Brogan, DR | 1 |
| Santos, VR | 1 |
| Musey, PI | 1 |
| Martino-Saltzman, D | 1 |
| Preedy, JR | 1 |
| Rozhin, J | 1 |
| Corombos, JD | 1 |
| Horwitz, JP | 1 |
| Lal, A | 1 |
| Wilken, H | 1 |
| Dässler, CG | 1 |
| Keenan, EJ | 1 |
| Alexieva-Figusch, J | 1 |
| de Jong, FH | 1 |
| Lamberts, WJ | 1 |
| van Gilse, HA | 1 |
| Klign, JG | 1 |
| Shultz, TD | 1 |
| Wilcox, RB | 1 |
| Spuehler, JM | 1 |
| Howie, BJ | 1 |
| Gomes, P | 1 |
| Cassanas, G | 1 |
| Hermida, R | 1 |
| Robel, P | 1 |
| Baulieu, EE | 1 |
| Lakatua, D | 1 |
| Mulder, NH | 1 |
| van der Ploeg, E | 1 |
| de Vries, EG | 1 |
| Ghilchik, MW | 1 |
| Zambetti, M | 1 |
| Ballerini, P | 1 |
| Gunasegaram, R | 1 |
| Loganath, A | 1 |
| Peh, KL | 1 |
| Thiagaraj, D | 1 |
| Kottegoda, SR | 1 |
| Ratnam, SS | 1 |
| Nabuurs, M | 1 |
| Mackay, WD | 1 |
| Edwards, MH | 1 |
| Argüelles, AE | 1 |
| Poggi, UL | 1 |
| Saborida, C | 1 |
| Hoffman, C | 1 |
| Chekherdemian, M | 1 |
| Blanchard, O | 1 |
| Herian, M | 2 |
| Swain, MC | 2 |
| Brennan, MJ | 1 |
| Shivas, AA | 2 |
| Sarfaty, G | 3 |
| Tallis, M | 3 |
| Sneddon, A | 2 |
| Steel, JM | 2 |
| Strong, JA | 2 |
| Wong, MS | 1 |
| Grattarola, R | 1 |
| Utsunomiya, J | 1 |
| Hamaguchi, E | 1 |
| Jensen, V | 3 |
| Kumaoka, S | 1 |
| Sakauchi, N | 2 |
| Abe, O | 2 |
| Kusama, M | 2 |
| Takatani, O | 2 |
| Hobe, G | 1 |
| Libby, PR | 5 |
| Burn, JI | 2 |
| Kato, N | 1 |
| Garnham, JR | 1 |
| Cameron, EH | 5 |
| Jones, T | 3 |
| Jones, D | 3 |
| Anderson, AB | 1 |
| Gleave, EN | 3 |
| Foreest, AP | 1 |
| Gleave, E | 1 |
| Stewart, HJ | 1 |
| Campbell, H | 2 |
| Lemon, HM | 1 |
| Miller, DM | 1 |
| Brownsey, B | 1 |
| Guillebaud, J | 1 |
| Lewis, A | 1 |
| Miller, W | 1 |
| Hamilton, T | 2 |
| Kley, HK | 1 |
| Krüskemper, HL | 1 |
| Babin, P | 1 |
| Payard, J | 1 |
| de Giacomoni, P | 1 |
| Saurel, J | 1 |
| Melville, E | 2 |
| Braunsberg, H | 2 |
| Boyd, A | 1 |
| Telford, J | 1 |
| Bordiushkov, IuN | 1 |
| Mindlin, SS | 1 |
| Verkhovtseva, AI | 1 |
| Nice, E | 1 |
| Williams, K | 1 |
| Hayes, C | 1 |
| Metcalf, MG | 1 |
| Bogdanova, AG | 1 |
| O'Higgins, N | 1 |
| Strubel, HB | 1 |
| Rindt, W | 1 |
| Schirazi, M | 1 |
| Killen, E | 1 |
| Millington, D | 1 |
| Jenner, DA | 1 |
| Leung, BS | 2 |
| Jack, W | 1 |
| Wood, DC | 2 |
| Lindell, TD | 1 |
| Krippaechne, WW | 1 |
| Saez, JM | 1 |
| Morera, AM | 1 |
| Dazord, A | 1 |
| Bertrand, J | 1 |
| Hähnel, R | 1 |
| Twaddle, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Non Randomized Study Evaluating the Role of Androgen Receptors as Targets for Therapy of Pre-treated Post-menopausal Patients With ER/PgR-negative/AR-positive or ER and/or PgRpositive/ AR-positive Metastatic Breast Cancer (ARTT)[NCT02000375] | Phase 2 | 20 participants (Actual) | Interventional | 2013-03-31 | Terminated (stopped due to Due to slow recruitment and recent new published data) | ||
| Effect of DHEA on Skin Aging - Placebo-Controlled and Randomized Phase III Study in Postmenopausal Women.[NCT00248989] | Phase 3 | 150 participants (Actual) | Interventional | 2004-11-01 | Completed | ||
| MOSAIC-P: Mindfulness Online for Symptom Alleviation and Improvement in Cancer of the Prostate[NCT03853902] | 30 participants (Actual) | Interventional | 2016-01-26 | Completed | |||
| Randomized Controlled Trial Comparing Mindfulness-Based Stress Reduction (MBSR) to Supportive-Expressive Therapy (SET) on Psychological and Biological Outcomes in Breast Cancer Patients[NCT00390169] | Phase 3 | 300 participants (Anticipated) | Interventional | 2006-10-31 | Active, not recruiting | ||
| Mind-Body Health in Uro-Oncology: A Randomized Controlled Trial[NCT03852030] | 120 participants (Actual) | Interventional | 2012-07-31 | Completed | |||
| Reducing the Effects of Active Surveillance Stress, Uncertainty and Rumination Thru Engagement in Mindfulness Education[NCT02871752] | 225 participants (Actual) | Interventional | 2016-08-10 | Completed | |||
| Who Benefits More? Optimising Mindfulness Based Interventions for Improved Psychological Outcomes[NCT04417153] | 1,000 participants (Anticipated) | Observational | 2019-09-20 | Recruiting | |||
| REDEFINE AYAO: Reducing Emotional Distress, Enhancing Function and Improving Network Engagement in Adolescent and Young Adult Oncology[NCT02495376] | 151 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| DHEA + Acolbifene Against Vasomotor Symptoms (Hot Flushes) in Postmenopausal Women (Placebo Controlled, Double Blind and Randomized Phase III Study to Evaluate the Effects of 12-Week Treatment With DHEA (Prasterone) and Acolbifene on Vasomotor Symptoms (H[NCT01452373] | Phase 3 | 238 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
| Extended Follow-up of Columbia, MO Serum Bank Participants[NCT00340210] | 6,720 participants (Actual) | Observational | 1999-01-14 | Completed | |||
| Phase II-III Placebo-Controlled, Study to Evaluate the Effects of DHEA on Vasomotor Symptoms (Hot Flashes) in Postmenopausal Women[NCT00317148] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2005-08-31 | Completed | ||
| A Placebo-controlled Study Examining the Morphological/Biochemical Effects of Intrarosa on the Vulvar Vestibule and Vagina in Women With Genitourinary Syndrome of Menopause/Vulvovaginal Atrophy[NCT03782480] | Phase 3 | 40 participants (Anticipated) | Interventional | 2019-03-02 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
49 reviews available for dehydroepiandrosterone and Breast Neoplasms
| Article | Year |
|---|---|
Functions of dehydroepiandrosterone in relation to breast cancer.
Topics: Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; H | 2022 |
A Systematic Review and Meta-Analysis of Smoking and Circulating Sex Hormone Levels Among Premenopausal Women.
Topics: Androgens; Breast Neoplasms; Contraceptives, Oral; Cross-Sectional Studies; Dehydroepiandrosterone; | 2022 |
Current challenges in the pharmacological management of genitourinary syndrome of menopause.
Topics: Atrophy; Breast Neoplasms; Dehydroepiandrosterone; Estrogens; Female; Humans; Menopause; Quality of | 2023 |
Current challenges in the pharmacological management of genitourinary syndrome of menopause.
Topics: Atrophy; Breast Neoplasms; Dehydroepiandrosterone; Estrogens; Female; Humans; Menopause; Quality of | 2023 |
Current challenges in the pharmacological management of genitourinary syndrome of menopause.
Topics: Atrophy; Breast Neoplasms; Dehydroepiandrosterone; Estrogens; Female; Humans; Menopause; Quality of | 2023 |
Current challenges in the pharmacological management of genitourinary syndrome of menopause.
Topics: Atrophy; Breast Neoplasms; Dehydroepiandrosterone; Estrogens; Female; Humans; Menopause; Quality of | 2023 |
A systematic review of randomised clinical trials - The safety of vaginal hormones and selective estrogen receptor modulators for the treatment of genitourinary menopausal symptoms in breast cancer survivors.
Topics: Breast Neoplasms; Cancer Survivors; Dehydroepiandrosterone; Estrogens; Female; Humans; Menopause; Ne | 2023 |
Breast Cancer: Targeting of Steroid Hormones in Cancerogenesis and Diagnostics.
Topics: Androstenedione; Biomarkers, Tumor; Breast Neoplasms; Dehydroepiandrosterone; Dihydrotestosterone; E | 2021 |
Management of postmenopausal vulvovaginal atrophy: recommendations of the International Society for the Study of Vulvovaginal Disease.
Topics: Administration, Intravaginal; Atrophy; Breast Neoplasms; Dehydroepiandrosterone; Estrogens; Female; | 2021 |
Managing Genitourinary Syndrome of Menopause in Breast Cancer Survivors Receiving Endocrine Therapy.
Topics: Aromatase Inhibitors; Breast Neoplasms; Cancer Survivors; Dehydroepiandrosterone; Estrogens; Female; | 2019 |
Recent advances in structure of progestins and their binding to progesterone receptors.
Topics: Acetylation; Antineoplastic Agents, Hormonal; Binding Sites; Breast Neoplasms; Dehydroepiandrosteron | 2015 |
The intracrinology of breast cancer.
Topics: Androgens; Aromatase; Breast; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfa | 2015 |
All sex steroids are made intracellularly in peripheral tissues by the mechanisms of intracrinology after menopause.
Topics: Aromatase Inhibitors; Breast Neoplasms; Dehydroepiandrosterone; Estrogen Receptor Modulators; Estrog | 2015 |
The potential adverse effects of aromatase inhibitors on wound healing: in vitro and in vivo evidence.
Topics: Adipose Tissue; Aged; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Bre | 2009 |
Testosterone therapy in women with androgen deficiency: Its time has come.
Topics: Androgens; Breast Neoplasms; Cardiovascular Diseases; Clinical Trials as Topic; Dehydroepiandrostero | 2010 |
Management of vulvovaginal atrophy-related sexual dysfunction in postmenopausal women: an up-to-date review.
Topics: Administration, Intravaginal; Adult; Aged; Aged, 80 and over; Atrophy; Breast Neoplasms; Complementa | 2012 |
[Intracrinology and dehydroepiandrosterone--a new perspective for the use of androgens in hormone replacement therapy in postmenopausal women].
Topics: Adult; Androgens; Animals; Breast Neoplasms; Dehydroepiandrosterone; Drug Therapy, Combination; Estr | 2011 |
[DHEA: desire and resistance].
Topics: Aged; Aging; Breast Neoplasms; Dehydroepiandrosterone; Erectile Dysfunction; Female; Humans; Libido; | 2002 |
Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Aged; Aged, 80 and over; Androgens; Animals; Bone Density; | 2003 |
Steroids as procarcinogenic agents.
Topics: Androgens; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Cytochrome P-45 | 2004 |
The role of androgens in hormone replacement therapy.
Topics: Adult; Age Factors; Aged; Androgens; Breast Neoplasms; Cardiovascular System; Dehydroepiandrosterone | 2005 |
Is dehydroepiandrosterone a hormone?
Topics: Adult; Aged; Androgen Antagonists; Animals; Breast; Breast Neoplasms; Castration; Dehydroepiandroste | 2005 |
Future perspectives of selective estrogen receptor modulators used alone and in combination with DHEA.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dehydroepiandrosterone; Female; Hu | 2006 |
Dehydroepiandrosterone, androgens and the mammary gland.
Topics: Androgens; Animals; Breast Neoplasms; Dehydroepiandrosterone; Female; Gonadal Steroid Hormones; Huma | 2006 |
Dehydroepiandrosterone (DHEA) and the menopause: an update.
Topics: Adjuvants, Immunologic; Breast Neoplasms; Cardiovascular Diseases; Cognition Disorders; Dehydroepian | 2007 |
Drug insight: breast cancer prevention and tissue-targeted hormone replacement therapy.
Topics: Aromatase Inhibitors; Breast Neoplasms; Dehydroepiandrosterone; Estrogen Antagonists; Female; Hormon | 2007 |
[Intracrinology of human breast carcinoma and aromatase].
Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Dehydroepiandrosterone; Estrogen | 2007 |
Androgen receptor as a target for the treatment of hormone receptor-negative breast cancer: an unchartered territory.
Topics: Androgen Receptor Antagonists; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; | 2008 |
Steroids in saliva for assessing endocrine function.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Age Factors; Breast Neoplasms; Child; Circadian | 1982 |
Quo vadis basic and clinical chronobiology: promise for health maintenance.
Topics: Adrenal Cortex; Alcoholism; Aldosterone; Biological Clocks; Blood Pressure; Breast Neoplasms; Cardio | 1983 |
Aminoglutethimide in the treatment of advanced breast cancer.
Topics: Adrenalectomy; Aged; Aminoglutethimide; Androstenedione; Breast Neoplasms; Clinical Trials as Topic; | 1984 |
Extraglandular oestrogen formation and serum binding of oestradiol: relationship to cancer.
Topics: Adipose Tissue; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrogens; Fem | 1981 |
The role of cytokines and sulphatase inhibitors in regulating oestrogen synthesis in breast tumours.
Topics: Breast Neoplasms; Cytokines; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol Dehyd | 1995 |
["Intracrinology". Autonomy and freedom of peripheral tissues].
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydroge | 1995 |
Physiological importance of dehydroepiandrosterone.
Topics: Breast Neoplasms; Cardiovascular Diseases; Dehydroepiandrosterone; Female; Humans; Insulin Resistanc | 1994 |
Endogenous hormones and breast cancer risk.
Topics: Breast Neoplasms; Case-Control Studies; Cohort Studies; Dehydroepiandrosterone; Dehydroepiandrostero | 1993 |
Adrenal androgen action in breast cancer.
Topics: Adrenal Glands; Androgens; Animals; Breast Neoplasms; Cell Division; Dehydroepiandrosterone; Estradi | 1996 |
Perspectives and progress in development of breast cancer chemopreventive drugs.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Dehydroepiandrosterone; Estrogen Antagon | 1997 |
DHEA: a biologist's perspective.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aging; Androgens; Animals; Breast Neoplasms; Dehydroepiandr | 1997 |
Dietary supplements of dehydroepiandrosterone in relation to breast cancer risk.
Topics: Animals; Breast Neoplasms; Dehydroepiandrosterone; Dietary Supplements; Female; Humans; Insulin-Like | 1999 |
Intracrinology: role of the family of 17 beta-hydroxysteroid dehydrogenases in human physiology and disease.
Topics: 17-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adult; Androgens; Breast Neoplasms; Dehydroepiandr | 2000 |
Endogenous sex hormones and breast cancer in postmenopausal women: reanalysis of nine prospective studies.
Topics: Aged; Androstenedione; Breast Neoplasms; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiand | 2002 |
Effect of a vegetarian diet and dexamethasone on plasma prolactin, testosterone and dehydroepiandrosterone in men and women.
Topics: Adult; Breast Neoplasms; Circadian Rhythm; Dehydroepiandrosterone; Dexamethasone; Diet; Diet, Vegeta | 1979 |
Biochemical aspects of cancer of the breast. Implications in diagnosis and treatment.
Topics: Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Female; Glycosaminoglycans; Humans; Lymphatic M | 1975 |
Kinetic, hormonal and clinical studies with aminoglutethimide in breast cancer.
Topics: Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide; Androstenedione; Breast Neoplasms; Dehy | 1977 |
Prolactin and human breast cancer: a review.
Topics: Adolescent; Adult; Aging; Breast Neoplasms; Child; Child, Preschool; Circadian Rhythm; Contraceptive | 1979 |
Human breast cancer: concerted role of diet, prolactin and adrenal C19-delta 5-steroids in tumorigenesis.
Topics: Adrenal Glands; Animals; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; D | 1992 |
Intracrinology.
Topics: Adrenal Glands; Androgens; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; | 1991 |
Intracrinology.
Topics: Adrenal Glands; Androgens; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; | 1991 |
Intracrinology.
Topics: Adrenal Glands; Androgens; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; | 1991 |
Intracrinology.
Topics: Adrenal Glands; Androgens; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; | 1991 |
Intracrinology.
Topics: Adrenal Glands; Androgens; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; | 1991 |
Intracrinology.
Topics: Adrenal Glands; Androgens; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; | 1991 |
Intracrinology.
Topics: Adrenal Glands; Androgens; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; | 1991 |
Intracrinology.
Topics: Adrenal Glands; Androgens; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; | 1991 |
Intracrinology.
Topics: Adrenal Glands; Androgens; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; | 1991 |
Breast development in puberty.
Topics: Adipose Tissue; Adolescent; Adult; Androgens; Breast; Breast Neoplasms; Cell Differentiation; Cell D | 1986 |
Control of secretion and the function of C19-delta 5-steroids of the human adrenal gland.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; | 1985 |
Competition between steroids for hormonal receptor.
Topics: Animals; Antineoplastic Agents; Body Fluids; Breast Neoplasms; Castration; Dehydroepiandrosterone; E | 1971 |
[Androgens. Biochemistry, pharmacodynamics and therapeutic use].
Topics: Anabolic Agents; Androgens; Androstenes; Breast Neoplasms; Carrier Proteins; Dehydroepiandrosterone; | 1973 |
18 trials available for dehydroepiandrosterone and Breast Neoplasms
265 other studies available for dehydroepiandrosterone and Breast Neoplasms
| Article | Year |
|---|---|
Safety of prasterone in breast cancer survivors treated with aromatase inhibitors: the VIBRA pilot study.
Topics: Aromatase Inhibitors; Atrophy; Breast Neoplasms; Cancer Survivors; Dehydroepiandrosterone; Estradiol | 2022 |
Longitudinal evaluation of dehydroepiandrosterone (DHEA), its sulfated form and estradiol with cancer-related cognitive impairment in early-stage breast cancer patients receiving chemotherapy.
Topics: Breast Neoplasms; Cognitive Dysfunction; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Est | 2022 |
Prechemotherapy Levels of Plasma Dehydroepiandrosterone and Its Sulfated Form as Predictors of Cancer-Related Cognitive Impairment in Patients with Breast Cancer Receiving Chemotherapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Cognitive Dysfunction; Cohort Studies; Dehydroepiandrostero | 2019 |
The role of hormones and aromatase inhibitors on breast tumor growth and general health in a postmenopausal mouse model.
Topics: Aging; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Dehydroepiandrosterone; Disease M | 2014 |
Combined inhibition of glycolysis, the pentose cycle, and thioredoxin metabolism selectively increases cytotoxicity and oxidative stress in human breast and prostate cancer.
Topics: Antioxidants; Breast Neoplasms; Cell Line, Tumor; Dehydroepiandrosterone; Deoxyglucose; Drug Synergi | 2015 |
Mimicking postmenopausal steroid metabolism in breast cancer cell culture: Differences in response to DHEA or other steroids as hormone sources.
Topics: 17-Hydroxysteroid Dehydrogenases; Apoptosis; Breast; Breast Neoplasms; Cell Cycle; Cell Proliferatio | 2016 |
Dehydroepiandrosterone inhibits events related with the metastatic process in breast tumor cell lines.
Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Growth Processes; Cell Line, Tumor; Cell Movement; | 2016 |
Sulfotransferase 2B1b in human breast: differences in subcellular localization in African American and Caucasian women.
Topics: Animals; Black or African American; Breast; Breast Neoplasms; Cell Line, Tumor; Dehydroepiandrostero | 2008 |
Structural basis for the selective inhibition of human 3beta-hydroxysteroid dehydrogenase 1 in human breast tumor MCF-7 cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Arginine; Aromatase Inhibitors; Blotting, Western; Breast Neoplasms | 2009 |
Association between alcohol intake and serum sex hormones and peptides differs by tamoxifen use in breast cancer survivors.
Topics: Alcohol Drinking; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cross-Sectional Studies; Dehydr | 2008 |
The functions of key residues in the inhibitor, substrate and cofactor sites of human 3beta-hydroxysteroid dehydrogenase type 1 are validated by mutagenesis.
Topics: 3-Hydroxysteroid Dehydrogenases; Amino Acids; Binding Sites; Breast Neoplasms; Dehydroepiandrosteron | 2010 |
Effects of CYP7B1-mediated catalysis on estrogen receptor activation.
Topics: Adjuvants, Immunologic; Anabolic Agents; Androstane-3,17-diol; Animals; Blotting, Western; Breast Ne | 2010 |
Low salivary testosterone levels in patients with breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estriol; Estron | 2010 |
Effects of dehydroepiandrosterone on proliferation, migration, and death of breast cancer cells.
Topics: Breast Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dehyd | 2011 |
Dihydrotestosterone induces p27 degradation via direct binding with SKP2 in ovarian and breast cancer.
Topics: Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Dehydroepiand | 2011 |
Breast ductal lavage for assessment of breast cancer biomarkers.
Topics: Adult; Aged; Analysis of Variance; Androstenedione; Antineoplastic Agents, Hormonal; Biomarkers, Tum | 2010 |
Sex steroid hormones in pairs of tumor and serum from breast cancer patients and pathobiological role of androstene-3β, 17β-diol.
Topics: Adult; Androstenediol; Androstenedione; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dehy | 2011 |
Identifying and treating sexual dysfunction in postmenopausal women: the role of estrogen.
Topics: Administration, Intravaginal; Aged; Breast Neoplasms; Dehydroepiandrosterone; Dosage Forms; Endometr | 2011 |
The DHEA metabolite 7β-hydroxy-epiandrosterone exerts anti-estrogenic effects on breast cancer cell lines.
Topics: Androsterone; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cycloox | 2012 |
Aromatase overexpression enhances the stimulatory effects of adrenal androgens on MCF7 breast cancer cells.
Topics: Adrenal Glands; Androgens; Androstenediol; Androstenedione; Aromatase; Breast Neoplasms; Cell Divisi | 2002 |
Sulfation of bisphenol A abolished its estrogenicity based on proliferation and gene expression in human breast cancer MCF-7 cells.
Topics: Arylsulfotransferase; Benzhydryl Compounds; Breast Neoplasms; Cell Division; Cytosol; Dehydroepiandr | 2002 |
Conversion of dehydroepiandrosterone sulfate at physiological plasma concentration into estrogens in MCF-7 cells.
Topics: Breast Neoplasms; Cell Division; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estrogens; | 2002 |
The relationship between urinary androst-16-en-3alpha-ol and urinary 11-deoxy-17-oxosteroid excretion.
Topics: 17-Ketosteroids; Anatomy; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Humans; Testostero | 1963 |
PLASMA ANDROGENS IN WOMEN. I. NORMAL AND NON-HIRSUTE FEMALES, OOPHORECTOMIZED AND ADRENALECTOMIZED PATIENTS.
Topics: 17-Ketosteroids; Adolescent; Adrenalectomy; Androgens; Androsterone; Blood Chemical Analysis; Breast | 1964 |
DIFFERENTIAL 17-OXOSTEROID EXCRETION IN WOMEN WITH CANCER OF THE BREAST FOLLOWING HYPOPHYSECTOMY.
Topics: 17-Ketosteroids; Androsterone; Breast; Breast Neoplasms; Chromatography; Dehydroepiandrosterone; Eti | 1964 |
ANDROGENS IN HUMAN BREAST CANCER.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenalectomy; Androgens; Androsterone; Breast N | 1964 |
[CLINICAL EVALUATION OF THE PROTEO-ANABOLIC ACTIVITY OF L-METHYL-DELTA ANDROSTENOLONE IN PATIENTS WITH MALIGNANT NEOPLASMS DURING ACTINOTHERAPY].
Topics: Anabolic Agents; Blood Protein Electrophoresis; Breast Neoplasms; Carcinoma, Bronchogenic; Cobalt Is | 1964 |
ENZYMIC SYNTHESIS OF STEROID SULFATES. II.
Topics: Adenine Nucleotides; Androsterone; Breast Neoplasms; Cortisone; Dehydroepiandrosterone; Drug Therapy | 1964 |
DIFFERENCES OF STEROID METABOLISM IN BREAST CANCER AFTER HORMONE STIMULATION.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Androgens; Androsterone; Breast Diseases; Breast Neoplasms | 1964 |
I. URINARY EXCRETION OF NEUTRAL 17-KETOSTEROIDS AND PREGNANDEIOL BY PATIENTS WITH BREAST CANCER AND BENIGN BREAST DISEASE.
Topics: 17-Ketosteroids; Androsterone; Breast Diseases; Breast Neoplasms; Dehydroepiandrosterone; Etiocholan | 1965 |
[METABOLISM AND METABOLIC REACTIONS AFTER INFUSION OF DEHYDROEPIANDROSTERONE PHOSPHATE IN BREAST CANCER AND MASTOPATHY. II. THE FORMATION OF DELTA-4-ANDROSTENE-3,17-DIONE, TESTOSTERONE AND 7-KETO-DEHYDROEPIANDROSTERONE].
Topics: Androgens; Androstenedione; Androstenes; Breast Diseases; Breast Neoplasms; Dehydroepiandrosterone; | 1964 |
THE DETERMINATION OF 17-OXOSTEROID SULPHATES IN HUMAN PLASMA.
Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenalectomy; Androsterone; Blood Chemical Analysis; | 1965 |
Postmenopausal breast cancer risk in relation to sex steroid hormones, prolactin and SHBG (Sweden).
Topics: Androstenedione; Breast Neoplasms; Case-Control Studies; Dehydroepiandrosterone; Estradiol; Estrone; | 2003 |
Estrogen and androgen receptors as comediators of breast cancer cell proliferation: providing a new therapeutic tool.
Topics: Biopsy, Needle; Breast Neoplasms; Cell Division; Dehydroepiandrosterone; Dose-Response Relationship, | 2004 |
Serum levels of sex hormones and breast cancer risk in premenopausal women: a case-control study (USA).
Topics: Adult; Androstenedione; Breast Neoplasms; Case-Control Studies; Dehydroepiandrosterone; Estradiol; F | 2004 |
Epidemiology of urinary melatonin in women and its relation to other hormones and night work.
Topics: Adult; Androstenedione; Androstenols; Biological Availability; Biomarkers; Body Mass Index; Breast N | 2004 |
Plasma adrenal androgens and risk of breast cancer in premenopausal women.
Topics: Androgens; Breast Neoplasms; Case-Control Studies; Cohort Studies; Dehydroepiandrosterone; Dehydroep | 2004 |
[Importance of timing of music therapy in chemotherapy of cancer patients].
Topics: Adrenocorticotropic Hormone; Adult; Analysis of Variance; Antineoplastic Combined Chemotherapy Proto | 2004 |
Alcohol and endogenous sex steroid levels in postmenopausal women: a cross-sectional study.
Topics: Aged; Alcohol Drinking; Androstenedione; Breast Neoplasms; Cross-Sectional Studies; Dehydroepiandros | 2005 |
Endogenous estrogen, androgen, and progesterone concentrations and breast cancer risk among postmenopausal women.
Topics: Aged; Androgens; Androstenedione; Breast Neoplasms; Case-Control Studies; Confidence Intervals; Dehy | 2004 |
Breast cancer after childhood cancer.
Topics: Breast Neoplasms; Child; Dehydroepiandrosterone; Female; Humans; Neoplasms; Neoplasms, Second Primar | 2005 |
Serum sex steroids in premenopausal women and breast cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC).
Topics: Adult; Breast Neoplasms; Case-Control Studies; Confidence Intervals; Confounding Factors, Epidemiolo | 2005 |
Dehydroepiandrosterone inhibits the progression phase of mammary carcinogenesis by inducing cellular senescence via a p16-dependent but p53-independent mechanism.
Topics: Adjuvants, Immunologic; Alkylating Agents; Animals; Breast Neoplasms; Carcinoma in Situ; Cell Transf | 2005 |
The association of plasma DHEA and DHEA sulfate with breast cancer risk in predominantly premenopausal women.
Topics: Adult; Breast Neoplasms; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfat | 2006 |
Serum concentrations of estrogens, sex hormone-binding globulin, and androgens and risk of breast cancer in postmenopausal women.
Topics: Aged; Androgens; Androstenediol; Breast Neoplasms; Dehydroepiandrosterone; Estrogens; Estrone; Femal | 2006 |
Human cytosolic sulfotransferase 2B1: isoform expression, tissue specificity and subcellular localization.
Topics: Amino Acid Sequence; Animals; Breast; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cel | 2006 |
Associations between the CYP17, CYPIB1, COMT and SHBG polymorphisms and serum sex hormones in post-menopausal breast cancer survivors.
Topics: Adolescent; Adult; Aryl Hydrocarbon Hydroxylases; Breast Neoplasms; Chromatography, High Pressure Li | 2007 |
Low-dose aminoglutethimide in treatment of advanced breast cancer.
Topics: Adrenal Glands; Aged; Aminoglutethimide; Breast Neoplasms; Castration; Dehydroepiandrosterone; Drug | 1984 |
Comparative studies of aromatase inhibitors in relation to the significance of estrogen synthesis in human mammary tumors.
Topics: Aminoglutethimide; Androgens; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Cyanoketone; | 1982 |
Aminoglutethimide in tamoxifen-resistant patients: The Melbourne Experience.
Topics: Adrenal Glands; Adult; Aged; Aminoglutethimide; Breast Neoplasms; Dehydroepiandrosterone; Depression | 1982 |
Serum androgen levels and the menstrual cycle in women with benign or malignant breast disease.
Topics: Adult; Breast Diseases; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Es | 1981 |
DHEA: "miracle" drug?
Topics: Adrenal Glands; Adult; Aged; Aging; Animals; Breast Neoplasms; Colonic Neoplasms; Dehydroepiandroste | 1982 |
Endocrine and therapeutic effects of aminoglutethimide in premenopausal patients with breast cancer.
Topics: Adult; Aminoglutethimide; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandro | 1982 |
Effects of tamoxifen on the serum levels of oestrogens and adrenocortical steroids in postmenopausal breast cancer patients.
Topics: Adrenal Cortex Hormones; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Fe | 1982 |
Factors affecting dehydroepiandrosterone sulphate levels in human breast secretions.
Topics: Adult; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Fibrocystic | 1981 |
Role of human adipose tissue in the production and metabolism of steroid hormones.
Topics: 17-alpha-Hydroxyprogesterone; Adipose Tissue; Androstenedione; Breast Neoplasms; Dehydroepiandroster | 1982 |
Endocrine effects of low dose aminoglutethimide alone in advanced postmenopausal breast cancer.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Aged; Aminoglutethimide; Androstenedione; Breast Neoplasms; Cos | 1983 |
Early menarche, a risk factor for breast cancer, indicates early onset of ovulatory cycles.
Topics: Adolescent; Aging; Breast Neoplasms; Child; Dehydroepiandrosterone; Estradiol; Female; Follicle Stim | 1983 |
Salivary cortisol and dehydroepiandrosterone sulphate levels in postmenopausal women with primary breast cancer.
Topics: Aged; Breast Neoplasms; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Fe | 1983 |
Endocrine changes associated with relapse in advanced breast cancer patients on aminoglutethimide therapy.
Topics: Aminoglutethimide; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Fe | 1984 |
[Serum hormonal activities in normal women and in patients with breast cancer].
Topics: Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Middle Aged; Prolactin; T | 1983 |
Adrenal androgen concentrations in breast tumours and in normal breast tissue. The relationship to oestradiol metabolism.
Topics: 17-Hydroxysteroid Dehydrogenases; Adenocarcinoma; Adult; Aged; Androstenediol; Androstenediols; Brea | 1984 |
Preliminary study of hormone determinations during aminoglutethimide therapy for advanced breast cancer.
Topics: Adult; Aged; Aldosterone; Aminoglutethimide; Bone Neoplasms; Breast Neoplasms; Dehydroepiandrosteron | 1984 |
Estrogen receptor status, adrenal androgens and 7 alpha-hydroxydehydroepiandrosterone in breast cancer patients.
Topics: Age Factors; Aged; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; | 1984 |
Influence of interferon on C19-steroids in urine of malignant skin melanoma and malignant breast neoplasm patients.
Topics: Adult; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Interferon Type I; Male; Melanoma; | 1984 |
Inhibition of steroid sulfatase activity by danazol.
Topics: Aminoglutethimide; Breast Neoplasms; Carcinoma; Culture Techniques; Danazol; Dehydroepiandrosterone; | 1984 |
Chronic anovulation.
Topics: Adrenocortical Hyperfunction; Amenorrhea; Anorexia Nervosa; Anovulation; Breast Neoplasms; Chronic D | 1984 |
Adrenal suppression by oral high-dose medroxyprogesterone acetate in breast cancer patients.
Topics: Adrenocorticotropic Hormone; Aged; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Female | 1984 |
The relationship of plasma 7 alpha-hydroxy dehydroepiandrosterone to disease stage and adrenal androgens in breast cancer patients.
Topics: Breast Diseases; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Neoplasm Staging | 1980 |
Aminoglutethimide and advanced breast cancer [proceedings].
Topics: Aminoglutethimide; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Kinetics; Menopause; Re | 1980 |
Rhythm-adjusted age effects in a concomitant study of twelve hormones in blood plasma of women.
Topics: Adolescent; Adult; Age Factors; Aldosterone; Analysis of Variance; Breast Neoplasms; Circadian Rhyth | 1980 |
Potency of the effect of D-stereoisomer of aminoglutethimide on adrenal and extraadrenal steroidogenesis.
Topics: Adrenal Glands; Aminoglutethimide; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Dehydr | 1980 |
Dehydroepiandrosterone and androst-5-ene-3 beta,17 beta-diol in human mammary cancer cytosolic and nuclear compartments and their relationship to estrogen receptor.
Topics: Androstenediol; Androstenediols; Breast Neoplasms; Cell Nucleus; Cross Reactions; Cytosol; Dehydroep | 1980 |
Hormone synthesis by primary breast carcinomas and prognosis in human breast cancer.
Topics: Androgens; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Neoplasm Stagi | 1980 |
Effects of adjuvant chemohormonal therapy on the ovarian and adrenal function of breast cancer patients.
Topics: Adrenal Cortex; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Dehydroepiandrosterone; Dr | 1980 |
Medical adrenalectomy with aminoglutethimide in the management of advanced breast cancer.
Topics: Adrenal Glands; Aminoglutethimide; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone | 1981 |
Abnormal 24-hr mean plasma concentrations of dehydroisoandrosterone and dehydroisoandrosterone sulfate in women with primary operable breast cancer.
Topics: Adult; Age Factors; Aged; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Me | 1981 |
Estrogenic effects of physiological concentrations of 5-androstene-3 beta, 17 beta-diol and its metabolism in MCF7 human breast cancer cells.
Topics: Androstenediol; Androstenediols; Biotransformation; Breast Neoplasms; Cell Line; Cell Nucleus; Cytos | 1981 |
How effective is surgical adrenalectomy in lowering steroid hormone concentrations?
Topics: Adrenalectomy; Aged; Aldosterone; Androgens; Androstenedione; Breast Neoplasms; Dehydroepiandrostero | 1982 |
[Steroid hormone content of the breast tissue in breast tumors].
Topics: Adolescent; Adult; Aged; Androstenedione; Breast; Breast Neoplasms; Dehydroepiandrosterone; Estradio | 1982 |
Serum prolactin, androgens, oestradiol and progesterone in adolescent girls with or without a family history of breast cancer.
Topics: Adolescent; Adult; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone | 1981 |
In vitro pregnenolone metabolism by mouse adrenal gland: II-Biosynthesis of androgens.
Topics: Adrenal Glands; Androgens; Animals; Breast Neoplasms; Castration; Dehydroepiandrosterone; Female; In | 1982 |
Metabolism of dehydroepiandrosterone sulphate by breast cysts: possible role in the development of breast cancer.
Topics: Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Fibrocystic Breast | 1995 |
Dehydroepiandrosterone concentration in breast cancer tissue is related to its plasma gradient across the mammary gland.
Topics: Adult; Aged; Arylsulfatases; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Middle Aged; | 1995 |
Changes in serum sex steroid levels during megestrol acetate therapy.
Topics: Adrenalectomy; Aged; Antibodies; Breast Neoplasms; Cross Reactions; Dehydroepiandrosterone; Estradio | 1994 |
The relationship of urinary and plasma androgens to steroid receptors and menopausal status in breast cancer patients and their influence on survival.
Topics: 17-Hydroxycorticosteroids; Adult; Aged; Androgens; Breast Neoplasms; Chemotherapy, Adjuvant; Dehydro | 1994 |
Physiological importance of dehydroepiandrosterone.
Topics: Breast Neoplasms; Cyproterone Acetate; Dehydroepiandrosterone; Estradiol; Female; Humans; Postmenopa | 1994 |
Steroid gradients across the cancerous breast: an index of altered steroid metabolism in breast cancer?
Topics: Adult; Aged; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfa | 1994 |
The relation of reported alcohol ingestion to plasma levels of estrogens and androgens in premenopausal women (Maryland, United States).
Topics: Adult; Alcohol Drinking; Androgens; Androstenedione; Body Mass Index; Body Weight; Breast Neoplasms; | 1994 |
Inhibition of steroid sulphatase activity by steroidal methylthiophosphonates: potential therapeutic agents in breast cancer.
Topics: Antineoplastic Agents; Arylsulfatases; Breast Neoplasms; Cholesterol; Dehydroepiandrosterone; Dose-R | 1994 |
ZR-75-1 breast cancer cells generate nonconjugated steroids from low density lipoprotein-incorporated lipoidal dehydroepiandrosterone.
Topics: Breast Neoplasms; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Fatty Acids; Fatty A | 1993 |
Effects of androgens on proliferation and progesterone receptor levels in T47D human breast cancer cells.
Topics: Androgens; Breast Neoplasms; Cell Division; Dehydroepiandrosterone; Dihydrotestosterone; Down-Regula | 1993 |
The role of insulin and renin in the pathogenesis of hormone-dependent neoplasias. b). Renin.
Topics: Adipose Tissue; Androstenedione; Blood Pressure; Breast Neoplasms; Dehydroepiandrosterone; Endometri | 1993 |
The role of insulin and renin in the pathogenesis of hormone-dependent neoplasias. a). Insulin.
Topics: Androstenedione; Blood Glucose; Body Weight; Breast Neoplasms; Dehydroepiandrosterone; Endometrial N | 1993 |
Chemoprevention of breast cancer.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Carci | 1996 |
Effects of soya consumption for one month on steroid hormones in premenopausal women: implications for breast cancer risk reduction.
Topics: Adult; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diet; Estradiol; Fe | 1996 |
[Adrenal steroids in patients with breast cancer and in women with age-related impaired glucose tolerance].
Topics: Age Factors; Blood Glucose; Breast Neoplasms; Dehydroepiandrosterone; Female; Glucose Intolerance; H | 1996 |
Role of glucose-6-phosphate dehydrogenase inhibition in the antiproliferative effects of dehydroepiandrosterone on human breast cancer cells.
Topics: Breast Neoplasms; Cell Division; Dehydroepiandrosterone; Female; Glucosephosphate Dehydrogenase; Hum | 1997 |
Relationship of serum dehydroepiandrosterone (DHEA), DHEA sulfate, and 5-androstene-3 beta, 17 beta-diol to risk of breast cancer in postmenopausal women.
Topics: Aged; Anabolic Agents; Androstenediol; Bias; Blood Donors; Breast Neoplasms; Case-Control Studies; C | 1997 |
Changes in serum estrogen levels in women during tamoxifen therapy.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrogens; Estr | 1997 |
Green tea, mistletoe, and more: Canadians test alternative cancer therapies.
Topics: Antineoplastic Agents; Breast Neoplasms; Camphor; Canada; Complementary Therapies; Dehydroepiandrost | 1997 |
Effect of dehydroepiandrosterone and the antiestrogen EM-800 on growth of human ZR-75-1 breast cancer xenografts.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Benzopyrans; Breast Neoplasms; Dehydroepia | 1998 |
Correspondence re: L. G. Boros et al., oxythiamine and dehydroepiandrosterone inhibit the nonoxidative synthesis of ribose and tumor cell proliferation. Cancer Res., 57: 4242-4248, 1997.
Topics: Antimetabolites; Breast Neoplasms; Carcinoma; Cell Division; DEAD-box RNA Helicases; Dehydroepiandro | 1998 |
C19 steroids estrogenic activity in human breast cancer cell lines: importance of dehydroepiandrosterone sulfate at physiological plasma concentration.
Topics: Breast Neoplasms; Dehydroepiandrosterone; Estrogens; Humans; Luciferases; Tumor Cells, Cultured | 1998 |
Re: Plasma sex steroid hormone levels and risk of breast cancer in postmenopausal women.
Topics: Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Female; Gonadal Steroid Hormones; Humans; Neopl | 1999 |
Elevated serum estradiol and testosterone concentrations are associated with a high risk for breast cancer. Study of Osteoporotic Fractures Research Group.
Topics: Aged; Androstenedione; Breast Neoplasms; Case-Control Studies; Dehydroepiandrosterone; Estradiol; Fe | 1999 |
Re: Plasma sex steroid hormone levels and risk of breast cancer in postmenopausal women.
Topics: Adult; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrogens, Conjugated (USP); Estrone; Fe | 1999 |
Adrenal androgens stimulate the proliferation of breast cancer cells as direct activators of estrogen receptor alpha.
Topics: Androgens; Androstenediol; Breast Neoplasms; Cell Division; Cloning, Molecular; Dehydroepiandrostero | 1999 |
Gonadotropins stimulate growth of MCF-7 human breast cancer cells by promoting intracellular conversion of adrenal androgens to estrogens.
Topics: Anastrozole; Androgens; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Chorionic | 2000 |
Dehydroepiandrosterone stimulates proliferation and gene expression in MCF-7 cells after conversion to estradiol.
Topics: Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; | 2001 |
The direct proliferative stimulus of dehydroepiandrosterone on MCF7 breast cancer cells is potentiated by overexpression of aromatase.
Topics: Aromatase; Breast Neoplasms; Cell Division; Dehydroepiandrosterone; Drug Synergism; Estradiol; Estro | 2001 |
Diet and breast cancer.
Topics: Animals; Breast Neoplasms; Catechin; Cattle; Coumaric Acids; Cyclohexenes; Dehydroepiandrosterone; D | 2002 |
Inhibition of carcinogen-activating enzymes by 16alpha-fluoro-5-androsten-17-one.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Biotransform | 2002 |
Ovarian function in patients receiving adjuvant chemotherapy for breast cancer.
Topics: Adult; Aged; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Dehydroepia | 1977 |
The in vitro synthesis of 7-hydroxy dehydroepiandrosterone by human mammary tissues.
Topics: Acetylation; Breast; Breast Neoplasms; Chromatography, Paper; Dehydroepiandrosterone; Female; Humans | 1975 |
Hormonal imbalance in breast cancer.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Androstenedione; Breast Neoplasms; Cholesterol; | 1975 |
Investigation of 17-ketosteriod excretion in mastopathia and premenopausal breast cancer.
Topics: 17-Ketosteroids; Adult; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Fem | 1975 |
Urinary excretion of 17-ketosteroids in patients suffering from mammary cancer.
Topics: 17-Ketosteroids; Aged; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Me | 1975 |
Urinary and plasma androgens and their relation to familial risk of breast cancer.
Topics: 17-Hydroxycorticosteroids; Adult; Age Factors; Aged; Androgens; Androsterone; Breast Neoplasms; Crea | 1975 |
Plasma hormone profiles in populations at different risk for breast cancer.
Topics: Adult; Androstenedione; Black People; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Female; G | 1976 |
The excretion of 17-ketosteroids in patients suffering from mastopathia fibrocystica and mammary carcinomas.
Topics: 17-Ketosteroids; Adult; Age Factors; Aged; Androsterone; Breast Diseases; Breast Neoplasms; Cysts; D | 1975 |
Plasma hormone levels in different ethnic populations of women.
Topics: Adrenal Glands; Adult; Africa; Androstenedione; Animals; Asian People; Black People; Breast Neoplasm | 1976 |
Proceedings: Interpretation of data on production and secretion rate measurements of DHEA and DHEAS.
Topics: Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Menopause; Sulfuric Acid Esters | 1975 |
Biogenesis of steroid hormones by human mammary gland in vivo and in vitro.
Topics: Androstenedione; Breast Neoplasms; Cyanoketone; Dehydroepiandrosterone; Female; Humans; In Vitro Tec | 1976 |
Plasma dehydroepiandrosterone concentration in normal women and in patients with benign and malignant breast disease.
Topics: 17-Ketosteroids; Adult; Aged; Breast; Breast Diseases; Breast Neoplasms; Chromatography, Gas; Dehydr | 1976 |
Plasma estrogens and androgens in male breast cancer.
Topics: Adult; Aged; Androgens; Androstenedione; Breast Neoplasms; Castration; Dehydroepiandrosterone; Dihyd | 1976 |
Dehydroepiandrosterone sulfotransferase as a possible shunt for the control of steroid metabolism in human mammary carcinoma.
Topics: Adrenalectomy; Breast Neoplasms; Carcinoma; Chemical Phenomena; Chemistry; Dehydroepiandrosterone; E | 1977 |
Steroid metabolism by human mammary carcinoma.
Topics: Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Female; Humans; Receptors, Estrogen; Sulfurtran | 1976 |
Adrenal function in breast cancer: the metabolism of pregnenolone in breast cancer patients.
Topics: Adrenal Cortex Function Tests; Adult; Aged; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans | 1976 |
Plasma dehydroepiandrosterone sulfate, androstenedione and cortisol, and urinary free cortisol excretion in breast cancer.
Topics: Adult; Age Factors; Aged; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; | 1977 |
Diet and endocrine-related cancer.
Topics: Adult; Animals; Asian People; Breast Neoplasms; Bromocriptine; Dehydroepiandrosterone; Dietary Fats; | 1977 |
Plasma androstenedione levels in women with breast cancer.
Topics: 17-Ketosteroids; Aged; Androstenedione; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Fema | 1977 |
Steroid sex hormones and prolactin in postmenopausal women with generalized mammary carcinoma during prolonged dexamethasone treatment.
Topics: Aged; Androgens; Androstenedione; Breast Neoplasms; Castration; Dehydroepiandrosterone; Dexamethason | 1977 |
The effect of 7beta, 17alpha-dimethyltestosterone (calusteron) on testosterone metabolism in women with advanced breast cancer.
Topics: Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Glucuronates; Human | 1977 |
Steroid hormones and human breast cancer. An hypothesis.
Topics: 17-Ketosteroids; Adrenal Glands; Breast Neoplasms; Cholesterol; Dehydroepiandrosterone; Estradiol; F | 1977 |
Hormonal changes following hypophysectomy in humans.
Topics: Androstenedione; Arginine; Breast Neoplasms; Cold Temperature; Dehydroepiandrosterone; Estradiol; Es | 1977 |
Analysis of dehydroepiandrosterone and androstenediol in human breast tissue using high resolution gas chromatography--mass spectrometry.
Topics: Adenofibroma; Androstenediol; Androstenediols; Breast; Breast Neoplasms; Chromatography, Gas; Dehydr | 1977 |
Thymus and breast cancer--plasma androgens, thymic pathology, and peripheral lymphocytes in myasthenia gravis.
Topics: Adult; Androgens; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Leukocyte | 1977 |
Dehydroepiandrosterone and androstenediol in human primary breast tumours.
Topics: Adult; Age Factors; Aged; Androstenediols; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; | 1978 |
Products of dehydroepiandrosterone metabolism by human mammary tumors and their influence on estradiol receptor binding.
Topics: Androstenediols; Animals; Binding, Competitive; Breast Neoplasms; Cytosol; Dehydroepiandrosterone; E | 1978 |
Adrenal dehydroepiandrosterone and human mammary cancer.
Topics: Adrenal Glands; Androstenediol; Animals; Binding, Competitive; Breast Neoplasms; Cell Nucleus; Cytos | 1978 |
Levels of principal 17-ketosteroid fractions in urine of breast cancer patients with or without malignant evolutive push.
Topics: 17-Ketosteroids; Adult; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Fem | 1978 |
Inhibition of spontaneous breast cancer formation in female C3H(Avy/a) mice by long-term treatment with dehydroepiandrosterone.
Topics: Animals; Body Weight; Breast Neoplasms; Dehydroepiandrosterone; Female; Glucosephosphate Dehydrogena | 1979 |
Aromatization of androgens by human breast cancer.
Topics: Adenocarcinoma; Adipose Tissue; Adult; Aged; Breast Neoplasms; Dehydroepiandrosterone; Estrogens; Fe | 1979 |
Urinary free cortisol, cortisone, cortisol sulfate, cortisone sulfate and 17-ketosteroids in breast cancer.
Topics: 17-Ketosteroids; Adult; Androsterone; Breast Neoplasms; Cortisone; Dehydroepiandrosterone; Etiochola | 1979 |
Relation between endocrine function and survival of patients with breast cancer after hypophysectomy.
Topics: Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Endocrine Glands; Female; Follicle Stimulati | 1979 |
Plasma and urinary androgens in women with varying degrees of risk of breast cancer.
Topics: Adult; Aged; Androstenediols; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Etiocholano | 1979 |
Metabolism of pregnenolone by human breast cancer. Evidence for 17 alpha-hydroxylase and 17,20-lyase.
Topics: 17-alpha-Hydroxypregnenolone; Aged; Aldehyde-Lyases; Androstenedione; Breast Neoplasms; Cytochrome P | 1979 |
Adrenal suppression with aminoglutethimide. III. Comparison of plasma delta 4- and delta 5-steroids in postmenopausal women treated for breast carcinoma.
Topics: 17-alpha-Hydroxypregnenolone; Aminoglutethimide; Androgens; Androstenedione; Breast Neoplasms; Castr | 1978 |
Interaction of delta-5-androstene-3beta, 17beta-diol with estradiol and dihydrotestosterone receptors in human myometrial and mammary cancer tissue.
Topics: Adult; Aged; Androstenediols; Androstenedione; Binding, Competitive; Breast Neoplasms; Cyproterone; | 1975 |
The steroid alcohol and estrogen sulfotransferases in rodent and human mammary tumors.
Topics: Alcohols; Animals; Breast Neoplasms; Castration; Chick Embryo; Dehydroepiandrosterone; Estrogens; Es | 1975 |
Proceedings: Inhibition of the binding of oestradiol to its specific receptor by C19 steroids in human mammary tumour and myometrial tissue.
Topics: Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Female; Humans; Receptors, Cell Surface; Struct | 1975 |
Androgens in postmenopausal breast cancer: excretion, production and interaction with estrogens.
Topics: 17-Ketosteroids; Aged; Androgens; Androstenedione; Binding, Competitive; Breast Neoplasms; Dehydroep | 1975 |
Metabolism of dehydroepiandrosterone by hormone dependent and hormone independent human breast carcinoma.
Topics: Androstane-3,17-diol; Androstanes; Binding Sites; Breast Neoplasms; Dehydroepiandrosterone; Dihydrot | 1975 |
Interaction between dehydroepiandrosterone, glucose-6-phosphate dehydrogenase, and cyclic adenosine-3',5'-monophosphate in neoplastic and normal human mammary tissue.
Topics: Breast; Breast Neoplasms; Cyclic AMP; Dehydroepiandrosterone; Female; Glucosephosphate Dehydrogenase | 1975 |
Proceedings: Androgens in human postmenopausal breast cancer.
Topics: Androgens; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Menopause; | 1975 |
Adrenal suppression with aminoglutethimide. I. Differential e-fects of aminoglutethimide on glucocorticoid metabolism as a rationale for use of hydrocortisone.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Breast Neoplasms; Castration; Dehydr | 1977 |
Dexamethasone suppressibility of plasma pregnenolone or dehydroepiandrosterone in gonadectomized patients.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Breast Neoplasms; Castration; Dehydroepiandrosterone; Dexa | 1979 |
Tissue androgens and the endocrine autonomy of breast cancer.
Topics: Adipose Tissue; Androgens; Androstenediols; Androstenedione; Breast Neoplasms; Dehydroepiandrosteron | 1992 |
Endocrine status in stage II vs. advanced premenopausal and postmenopausal breast cancer patients.
Topics: Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Endocrine Glands; Estradiol; Female; Foll | 1992 |
Estrogen receptor and C19-5-ene-steroid concentrations in the nuclear fraction from human breast carcinoma tissue.
Topics: Androstenediol; Androstenols; Breast Neoplasms; Carcinoma; Cell Nucleus; Dehydroepiandrosterone; Fem | 1992 |
Relationship of prediagnostic serum levels of dehydroepiandrosterone and dehydroepiandrosterone sulfate to the risk of developing premenopausal breast cancer.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Case-Control Studies; Child; Dehydroep | 1992 |
Hormone levels in vegetarian and nonvegetarian teenage girls: potential implications for breast cancer risk.
Topics: Adolescent; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diet; Diet, Ve | 1992 |
Oestrogen sulphatase activity in hormone-dependent and hormone-independent breast-cancer cells: modulation by steroidal and non-steroidal therapeutic agents.
Topics: Breast Neoplasms; Cell Division; Danazol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Et | 1992 |
Endocrine status in patients with mammary gland diseases: correlation between steroid hormones and sex steroid binding globulin.
Topics: Adult; Aged; Aged, 80 and over; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Dehydroep | 1991 |
Dehydroepiandrosterone and estrone 17-ketosteroid reductases in MCF-7 human breast cancer cells.
Topics: 17-Hydroxysteroid Dehydrogenases; Alcohol Oxidoreductases; Androstenediol; Breast Neoplasms; Carcino | 1990 |
Hormone levels in older women: a study of post-menopausal breast cancer patients and healthy population controls.
Topics: Aged; Aged, 80 and over; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Female; Human | 1990 |
Biological effects of adrenal androgens on MCF-7 and BT-20 human breast cancer cells.
Topics: Androstenediol; Androstenediols; Breast Neoplasms; Cell Division; Dehydroepiandrosterone; Dehydroepi | 1990 |
Relationship of serum levels of dehydroepiandrosterone and dehydroepiandrosterone sulfate to the risk of developing postmenopausal breast cancer.
Topics: Aged; Aged, 80 and over; Blood Donors; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandroster | 1990 |
Steroid patterns of benign breast disease.
Topics: Adenofibroma; Breast Neoplasms; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Dehydr | 1990 |
The urinary dehydroepiandrosterone, androsterone and etiocholanolone excretion of healthy women and women with benign and malignant breast disease.
Topics: Adenofibroma; Adult; Androsterone; Breast Diseases; Breast Neoplasms; Chromatography, Thin Layer; Cy | 1990 |
[Prolactin receptors and breast cancer].
Topics: Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Female; Humans; Neoplasms, Hormone-Dependent; P | 1990 |
Dehydroepiandrosterone sulfate and breast cancer risk.
Topics: Age Factors; Aged; Breast Neoplasms; Cross-Sectional Studies; Dehydroepiandrosterone; Dehydroepiandr | 1990 |
Aromatisation of dehydroepiandrosterone by hormone dependent human mammary cancer MCF-7 subcellular fractions.
Topics: Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Neoplasms, Hormone-Dependent; Subcellular | 1990 |
Androgens and breast cancer in premenopausal women.
Topics: Adult; Androgens; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone | 1989 |
Extensive esterification of adrenal C19-delta 5-sex steroids to long-chain fatty acids in the ZR-75-1 human breast cancer cell line.
Topics: Acetylation; Adrenal Cortex; Androstenediol; Androstenediols; Breast Neoplasms; Cell Line; Dehydroep | 1989 |
A comparison of the endocrine effects of low dose aminoglutethimide with and without hydrocortisone in postmenopausal breast cancer patients.
Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Dehydroep | 1985 |
Effects of tamoxifen on testosterone metabolism in postmenopausal women with breast cancer.
Topics: Aged; Breast Neoplasms; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Female; Humans; Kine | 1985 |
Uptake and concentration of steroid hormones in mammary tissues.
Topics: Adult; Androgens; Androstenediol; Biopsy; Breast; Breast Diseases; Breast Neoplasms; Cell Nucleus; C | 1986 |
Hormonal correlates of apocrine secretion in the breast.
Topics: Apocrine Glands; Breast; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; E | 1986 |
Treatment of advanced postmenopausal breast cancer with an aromatase inhibitor, 4-hydroxyandrostenedione: phase II report.
Topics: Adult; Aged; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Dehydroepiandrosterone; Drug E | 1986 |
Endocrine treatment of breast cancer: effects upon intratumoral estrone sulfate metabolism and peripheral steroid levels.
Topics: Aminoglutethimide; Breast Neoplasms; Danazol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate | 1986 |
Endocrine effects of low dose aminoglutethimide with hydrocortisone--an optimal hormone suppressive regimen.
Topics: Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms | 1986 |
Stimulation of cell proliferation and estrogenic response by adrenal C19-delta 5-steroids in the ZR-75-1 human breast cancer cell line.
Topics: Androstenediol; Androstenediols; Breast Neoplasms; Cell Division; Cell Line; Dehydroepiandrosterone; | 1986 |
Long term effects of a first pregnancy on the hormonal environment: estrogens and androgens.
Topics: Adolescent; Adult; Androgens; Breast Neoplasms; Cross-Sectional Studies; Dehydroepiandrosterone; Deh | 1987 |
Endocrine steroid sulfotransferases: steroid alcohol sulfotransferase from human breast carcinoma cell line MCF-7.
Topics: Breast Neoplasms; Cell Line; Chemical Phenomena; Chemistry; Cytosol; Dehydroepiandrosterone; Humans; | 1986 |
Determination of dehydroepiandrosterone and dehydroepiandrosterone sulphate in blood and tissue. Studies of normal women and women with breast or endometrial cancer.
Topics: Adult; Age Factors; Aged; Body Weight; Breast Neoplasms; Circadian Rhythm; Cross Reactions; Dehydroe | 1987 |
The effects of low and high dose medroxyprogesterone acetate on sex steroids and sex hormone binding globulin in postmenopausal breast cancer patients.
Topics: Androstenedione; Antineoplastic Agents; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandroste | 1987 |
[Dehydroepiandrosterone and other endocrine parameters in breast cancer].
Topics: Androstenediol; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Female; Humans; Sex Hormone-Bin | 1987 |
Adrenal C19-5-ene steroids induce full estrogenic responses in rat pituitary gonadotrophs.
Topics: Androstenediol; Androstenediols; Animals; Breast Neoplasms; Cells, Cultured; Dehydroepiandrosterone; | 1987 |
The mechanism of hormone-sensitive breast cancer progression on antiestrogen therapy. Implications for treatment and protocol planning.
Topics: Adrenal Glands; Adrenalectomy; Adult; Aged; Breast Neoplasms; Castration; Dehydroepiandrosterone; Es | 1987 |
Endocrine effects of aminoglutethimide plus hydrocortisone versus effects of high dose of hydrocortisone alone in postmenopausal metastatic breast cancer.
Topics: Aged; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Breast Neo | 1987 |
Dietary and hormonal interrelationships in premenopausal women: evidence for a relationship between dietary nutrients and plasma prolactin levels.
Topics: Adult; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diet, Vegetarian; D | 1987 |
[Blood levels of dehydroepiandrosterone sulfate (DHEA-S) and the risk of breast cancer].
Topics: Adolescent; Adult; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; | 1988 |
Clinical and endocrine effects of cyproterone acetate in postmenopausal patients with advanced breast cancer.
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Cyproterone; | 1988 |
The effects of androgens and cortisol on the in vivo metabolism of oestradiol.
Topics: Aged; Androgens; Androstenediol; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Su | 1988 |
The hydrolysis of estrone sulfate and dehydroepiandrosterone sulfate by MCF-7 human breast cancer cells.
Topics: Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estrone; Female; Humans; H | 1988 |
Hormonal changes induced by the pure antiandrogen flutamide in postmenopausal women with advanced breast cancer.
Topics: Anilides; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestoster | 1988 |
High dose ketoconazole: endocrine and therapeutic effects in postmenopausal breast cancer.
Topics: 17-alpha-Hydroxyprogesterone; Aged; Aged, 80 and over; Androstenedione; Breast Neoplasms; Dehydroepi | 1988 |
Steroidogenic expression of delta 5-3 beta-hydroxy pathway of androgen biosynthesis by human breast carcinoma.
Topics: 17-alpha-Hydroxypregnenolone; Acetyl Coenzyme A; Adult; Aged; Androgens; Breast Neoplasms; Carcinoma | 1986 |
The identification, quantification and possible origin of non-polar conjugates in human plasma.
Topics: Acne Vulgaris; Adult; Aged; Androstenediol; Breast Neoplasms; Dehydroepiandrosterone; Female; Hirsut | 1985 |
Endogenous concentration and subcellular distribution of androgens in normal and malignant human breast tissue.
Topics: Adolescent; Adult; Age Factors; Aged; Androgens; Androstenediol; Breast; Breast Neoplasms; Cell Nucl | 1985 |
Relation between plasma-cortisol, plasma-androgen-sulphates, and immune response in women with breast cancer.
Topics: Adult; Aged; Androgens; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Hydr | 1971 |
Endocrine profiles and breast cancer.
Topics: 11-Hydroxycorticosteroids; Adult; Aged; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estriol | 1973 |
Effect of steroidal contraceptives on levels of plasma androgen sulphates and cortisol.
Topics: Adult; Androsterone; Binding, Competitive; Blood Proteins; Breast Neoplasms; Chromatography, Gel; Co | 1973 |
Urinary and plasma androgens in benign breast disease. Possible relation to breast cancer.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Age Factors; Aged; Androgens; Breast Diseases; Br | 1973 |
Metabolism of androgens by human breast tissue.
Topics: Adenofibroma; Adult; Androgens; Breast; Breast Neoplasms; Carcinoma; Chromatography, Thin Layer; Deh | 1973 |
Basic results of a study of bilateral adrenalectomy for advanced breast cancer. Urinary steroids and related data in 148 patients.
Topics: 17-Ketosteroids; Adrenalectomy; Adult; Androsterone; Body Surface Area; Breast; Breast Neoplasms; Ch | 1973 |
Effect of thyroid funtion and of obesity on discriminant function for mammary carcinoma.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Androgens; Androsterone; Breast Neoplasms; | 1968 |
A correlation between urinary steroid metabolites and pathways of steroidogenesis in human breast-tumour tissue.
Topics: 17-Ketosteroids; Adenofibroma; Adrenalectomy; Adult; Aged; Androstanes; Breast Neoplasms; Carcinoma; | 1968 |
Excretion of urinary 17-hydroxycorticosteroids and 11-deoxy-17-oxosteroids by women using steroidal contraceptives.
Topics: 17-Hydroxycorticosteroids; Adult; Age Factors; Androsterone; Breast Neoplasms; Channel Islands; Cont | 1969 |
Probability of a woman with advanced breast cancer responding to adrenalectomy or hypophysectomy.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Adult; Age Factors; Androsterone; Breast | 1970 |
[Metabolism and metabolic reaction following the infusion of dehydro-epiandrosterone-phosphate in breast cancer and mastopathies. 3. Behavior of estrogens].
Topics: Androsterone; Breast Diseases; Breast Neoplasms; Dehydroepiandrosterone; Estrogens; Female; Humans; | 1965 |
The possibility of predicting the response of patients with early breast cancer to subsequent endocrine ablation.
Topics: 17-Hydroxycorticosteroids; Adrenalectomy; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Et | 1965 |
[Comparing metabolic studies following infusion of dehydroepiandrosterone sulfate and dehydroepiandrosterone phosphate].
Topics: 17-Ketosteroids; Adult; Androgens; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Estradiol | 1965 |
[Comparing metabolic studies following infusion of delta-4-androstene-3,17-dione, testosterone phosphate and dehydroepiandrosterone phosphate].
Topics: 17-Ketosteroids; Adult; Androgens; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Estradiol | 1965 |
Urinary excretion of 11-deoxy-17-ketosteroids by patients with breast cancer with or without ovulatory cycles.
Topics: Adult; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Midd | 1967 |
The urinary excretion of 11-deoxy-17-oxosteroids and 17-hydroxycorticosteroids by normal Japanese and British women.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Androsterone; Breast Neoplasms; Dehydroepia | 1967 |
In vivo steroidogenesis by the human adrenal gland.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenalectomy; Androsterone; Breast Neoplasms; Crystalliz | 1967 |
Urinary 17-ketosteroid excretion of women with advanced breast cancer.
Topics: 17-Ketosteroids; Adrenalectomy; Adult; Aged; Androsterone; Asian People; Breast Neoplasms; Chemistry | 1968 |
[On the metabolism of phosphates and sulfates of androsterone and epiandrosterone].
Topics: 17-Ketosteroids; Androgens; Androstanes; Androsterone; Breast Diseases; Breast Neoplasms; Chromatogr | 1966 |
In vivo perfusion of the human adrenal gland and ovary in patients with mammary cancer.
Topics: Adrenal Glands; Androgens; Breast Neoplasms; Chromatography, Paper; Dehydroepiandrosterone; Estradio | 1968 |
Conjugation of steroid hormones by normal and neoplastic tissues.
Topics: Adult; Aged; Breast; Breast Neoplasms; Chromatography, Paper; Dehydroepiandrosterone; Desoxycorticos | 1968 |
Sunthesis of ovarian steroids in vivo in women with mammary cancer.
Topics: Breast Neoplasms; Castration; Dehydroepiandrosterone; Female; Gonadal Steroid Hormones; Humans; Ovar | 1968 |
A comparison of urinary 17-hydroxycorticosteroid and 11-deoxy-17-oxosteroid excretion in obesity, in thyroid dysfunction and in early breast cancer.
Topics: 17-Hydroxycorticosteroids; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; | 1969 |
[Clinical study of urinary 17-ketosteroid fractions in breast cancer--correlation with the effect of adrenalectomy in progressive breast cancer].
Topics: 17-Ketosteroids; Adrenalectomy; Adult; Aged; Breast Neoplasms; Dehydroepiandrosterone; Female; Human | 1968 |
Conjugated and unconjugated dehydroepiandrosterone, aetiocholanolone and androsterone in the peripheral plasma of patients with cancer of the breast, ovary, uterus or prostate.
Topics: Adult; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Male | 1969 |
Conjugation of steroid hormones by breast cancer tissue and selection of patients for adrenalectomy.
Topics: Adrenalectomy; Aged; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Humans; Liver; Li | 1969 |
Further studies on the relationship between C19- and C21-steroid synthesis in the human adrenal gland.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal | 1969 |
Lack of sulfate-activating enzymes in human breast tumors.
Topics: Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Female; Humans; Nucleotidyltransferases; Phosph | 1970 |
Steroid metabolism by human breast tumours.
Topics: 17-Ketosteroids; Androstanes; Breast Neoplasms; Chromatography, Thin Layer; Dehydroepiandrosterone; | 1970 |
Adrenal function in breast cancer: biogenesis of androgens and cortisol by the human adrenal gland in vivo.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Adrenalectomy; Adult; Aged; Androgens | 1970 |
The biogenesis of androgens and cortisol by the human adrenal gland in vivo.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androgens; Breast Neoplasms; Dehydroepiandrosterone; F | 1970 |
Steroid metabolism by human breast tumours.
Topics: 17-Ketosteroids; Androstanes; Breast Neoplasms; Dehydroepiandrosterone; Dihydrotestosterone; Female; | 1970 |
Benign and malignant breast disease in South Wales: a study of urinary steroids.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Androsterone; Breast Diseases; Breast Neoplasms; | 1970 |
Hormonal influences in breast cancer.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Adult; Age Factors; Androsterone; Animals | 1971 |
C19-steroid biosynthesis in the human adrenal gland.
Topics: Adrenal Glands; Alcohols; Androstanes; Breast Neoplasms; Carbon Isotopes; Chromatography, Thin Layer | 1971 |
Increase in urinary excretion of oestrogen on administration of dehydroepiandrosterone sulphate to an adrenalectomized, oophorectomized patient with breast cancer.
Topics: Adrenalectomy; Adult; Breast Neoplasms; Castration; Chromatography; Dehydroepiandrosterone; Estradio | 1971 |
A single method for determination of urine steroids. I. Levels of testosterone, epitestosterone and 17-ketosteroid fractions. II. Specific activities of testosterone, androsterone and etiocholanolone and production rate of testosterone following administr
Topics: 17-Ketosteroids; Adolescent; Adult; Aged; Androsterone; Breast Neoplasms; Carbon Isotopes; Carcinoma | 1970 |
Plasma dehydroepiandrosterone sulphate levels in patients with benign and malignant breast disease.
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Androsterone; Breast Neoplasms; Chromatography, G | 1972 |
A rapid method for the analysis of enzyme hydrolysable 11-deoxy-17-oxosteroids in urine.
Topics: 17-Ketosteroids; Androsterone; Breast Neoplasms; Chromatography, Ion Exchange; Dehydroepiandrosteron | 1972 |
The relation between sebum production and plasma 17-oxosteroid levels in normal women and in patients with breast cancer.
Topics: Adult; Age Factors; Aged; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Methods; Middle | 1972 |
Steroidogenesis in human and rat mammary adenocarcinoma.
Topics: Adenocarcinoma; Animals; Benz(a)Anthracenes; Breast Neoplasms; Carbon Isotopes; Chromatography, Thin | 1972 |
[Several steroid derivatives in breast tumors. Histo-enzymological study].
Topics: Biopsy; Breast; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Female; Histocytochemistry; Hum | 1973 |
Androgen production and conversion to estrogens in normal postmenopausal women and in selected breast cancer patients.
Topics: 17-Ketosteroids; Aged; Androgens; Androstenedione; Androsterone; Breast Neoplasms; Carbon Isotopes; | 1973 |
Hormones in the aetiology and clinical course of breast cancer.
Topics: Adult; Age Factors; Aged; Androgens; Animals; Breast Neoplasms; Carcinogens; Dehydroepiandrosterone; | 1972 |
Steroid sulphation in vitro by human breast cancer tissue.
Topics: Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Female; Humans; In Vitro Techniques; Menopause; | 1973 |
Androgen metabolism in human neoplastic and normal breast tissue.
Topics: Androgens; Breast; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; In Vitro Techniques; Te | 1973 |
[The mechanism of action of hydrocortisone administered by lumbar puncture in breast cancer].
Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Androsterone; Br | 1973 |
Simultaneous estimation of pregnenolone, 17-hydroxypregnenolone and dehydroepiandrosterone by gas-liquid radiochromatography.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenalectomy; Breast Neoplasms; Carbon Radioisotopes; | 1974 |
Steroid sulfatase activities in human breast tumors.
Topics: Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Sulfatases; Testostero | 1974 |
Effect of age, obesity, starvation, and changes in adrenocortical and ovarian activity on the urinary excretion of dehydroepiandrosterone relative to androsterone plus etiocholanolone: relevance to the measurement of breast cancer discriminants in women.
Topics: Adrenal Glands; Age Factors; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Dexamethasone; | 1974 |
[Influence of age and menopause duration on the excretion of steroid hormones in precancerous conditions and cancer of the breast].
Topics: Adult; Age Factors; Androsterone; Breast Diseases; Breast Neoplasms; Dehydroepiandrosterone; Etiocho | 1974 |
Proceedings: Pregnenolone metabolism in patients with carcinoma.
Topics: Breast Neoplasms; Carcinoma; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Metabolic Clear | 1974 |
Cytostatic effects of G-6-PDH inhibitors in cell cultures from normal and neoplastic tissue.
Topics: Breast Neoplasms; Cells, Cultured; Dehydroepiandrosterone; DNA; Female; Glucosephosphate Dehydrogena | 1974 |
Studies on steroic sulphation and binding by human malignant tumours.
Topics: Adult; Aged; Binding Sites; Breast Neoplasms; Carbon Radioisotopes; Dehydroepiandrosterone; Estradio | 1974 |
Endogenous steroid concentrations in human breast tumours determined by high-resolution mass fragmentography.
Topics: Androsterone; Breast Neoplasms; Chromatography, Gas; Dehydroepiandrosterone; Estradiol; Estriol; Est | 1974 |
Steroid sulfurylation in normal tissues and mammary tumors: a micro method.
Topics: Adenosine Triphosphate; Adrenal Gland Neoplasms; Adult; Aged; Animals; Binding Sites; Breast Neoplas | 1972 |
Studies on the sulphate esters of dehydroepiandrosterone and androsterone in the blood of women with breast cancer.
Topics: 17-Ketosteroids; Adult; Aged; Androsterone; Breast Neoplasms; Chromatography, Gas; Dehydroepiandrost | 1974 |
Conjugation of steroid hormones by breast-cancer tissue and selection of patients for adrenalectomy.
Topics: Adrenalectomy; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrogens, Conjugated (USP); Fem | 1969 |
Predictability of response to endocrine ablation in advanced breast carcinoma. A correlation to estrogen receptor and steroid sulfurylation.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Breast Neoplasms; Dehydroepiandrosterone; Estra | 1973 |
Adrenal and testicular contribution to plasma oestrogens.
Topics: 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Androstanes; Breast Neopl | 1972 |
Steroid metabolism by human breast and rat mammary carcinomata.
Topics: Adult; Androstanes; Animals; Benz(a)Anthracenes; Breast Neoplasms; Carbon Radioisotopes; Carcinoma; | 1974 |
The steroid specificity of the estrogen-receptor of human breast carcinoma.
Topics: Androstanes; Androstenols; Binding Sites; Breast; Breast Neoplasms; Carcinoma; Cytosol; Dehydroepian | 1974 |
The effect of NADPH on steroidogenesis by the human adrenal gland in vivo.
Topics: Adrenal Glands; Adrenalectomy; Breast Neoplasms; Castration; Dehydroepiandrosterone; Female; Humans; | 1969 |