Page last updated: 2024-11-07

dehydroepiandrosterone and Brain Ischemia

dehydroepiandrosterone has been researched along with Brain Ischemia in 6 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Forebrain ischemia was induced for 10 min using a modified four-vessel occlusion technique, with hippocampal neuronal injury assessed at 7 days post-ischemically and expressed as a percentage of total cells."5.31Dehydroepiandrosterone (DHEA) reduces neuronal injury in a rat model of global cerebral ischemia. ( Buchan, AM; Klein, G; Li, H; Sun, P, 2001)
"It was identified that muscle atrophy could be induced during 7 days after a cerebral infarction, and DHEA administration during the early stages of a cerebral infarction might attenuate muscle atrophy."1.32[Effect of DHEA on hindlimb muscles in a focal cerebral ischemia model rat]. ( An, GJ, 2004)
"Forebrain ischemia was induced for 10 min using a modified four-vessel occlusion technique, with hippocampal neuronal injury assessed at 7 days post-ischemically and expressed as a percentage of total cells."1.31Dehydroepiandrosterone (DHEA) reduces neuronal injury in a rat model of global cerebral ischemia. ( Buchan, AM; Klein, G; Li, H; Sun, P, 2001)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zaric, M1
Drakulic, D1
Stojanovic, IG1
Mitrovic, N1
Grkovic, I1
Martinovic, J1
Yabuki, Y1
Shinoda, Y1
Izumi, H1
Ikuno, T1
Shioda, N1
Fukunaga, K1
An, GJ1
Aragno, M1
Parola, S1
Brignardello, E1
Mauro, A1
Tamagno, E1
Manti, R1
Danni, O1
Boccuzzi, G1
Li, H1
Klein, G1
Sun, P1
Buchan, AM1
Shin, CY1
Choi, JW1
Jang, ES1
Ju, C1
Kim, WK1
Kim, HC1
Choi, CR1
Ko, KH1

Other Studies

6 other studies available for dehydroepiandrosterone and Brain Ischemia

ArticleYear
Regional-specific effects of cerebral ischemia/reperfusion and dehydroepiandrosterone on synaptic NMDAR/PSD-95 complex in male Wistar rats.
    Brain research, 2018, 06-01, Volume: 1688

    Topics: Animals; Brain Ischemia; Dehydroepiandrosterone; Disks Large Homolog 4 Protein; Hippocampus; Male; N

2018
Dehydroepiandrosterone administration improves memory deficits following transient brain ischemia through sigma-1 receptor stimulation.
    Brain research, 2015, Oct-05, Volume: 1622

    Topics: Adenosine Triphosphate; Animals; Anisoles; Brain Ischemia; CA1 Region, Hippocampal; Calcium-Calmodul

2015
[Effect of DHEA on hindlimb muscles in a focal cerebral ischemia model rat].
    Taehan Kanho Hakhoe chi, 2004, Volume: 34, Issue:1

    Topics: Animals; Brain Ischemia; Dehydroepiandrosterone; Hindlimb; Male; Muscle, Skeletal; Muscular Atrophy;

2004
Dehydroepiandrosterone prevents oxidative injury induced by transient ischemia/reperfusion in the brain of diabetic rats.
    Diabetes, 2000, Volume: 49, Issue:11

    Topics: Animals; Antioxidants; Brain Ischemia; Cell Membrane; Dehydroepiandrosterone; Diabetes Mellitus, Exp

2000
Dehydroepiandrosterone (DHEA) reduces neuronal injury in a rat model of global cerebral ischemia.
    Brain research, 2001, Jan-12, Volume: 888, Issue:2

    Topics: Animals; Brain Ischemia; Dehydroepiandrosterone; Disease Models, Animal; Dose-Response Relationship,

2001
Dehydroepiandrosterone inhibits the death of immunostimulated rat C6 glioma cells deprived of glucose.
    Brain research, 2001, Dec-20, Volume: 922, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Astrocytes; Brain; Brain Ischemia; Cell Death; Cytokines; Dehydroep

2001