dehydroepiandrosterone has been researched along with Brain Injuries in 7 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Progesterone and dehydroepiandrosterone (DHEA) are neuroactive steroids that modulate neuronal and astroglial function and have neuroprotective effects in different experimental models, being potential candidates to the development of new therapeutic approaches for brain and spinal cord injuries." | 4.93 | Astrocytes as a target for neuroprotection: Modulation by progesterone and dehydroepiandrosterone. ( Arbo, BD; Bennetti, F; Ribeiro, MF, 2016) |
| "Allopregnanolone levels were inversely associated with low back pain (P=0." | 3.76 | Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001. ( Calnaido, RP; Hamer, RM; Keefe, FJ; Kilts, JD; Marx, CE; Massing, MW; Morey, RA; Naylor, JC; Parke, G; Payne, VM; Shampine, LJ; Strauss, JL; Tupler, LA; Youssef, NA, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pluchino, N | 1 |
| Santoro, A | 1 |
| Casarosa, E | 1 |
| Wenger, JM | 1 |
| Genazzani, AD | 1 |
| Petignat, P | 1 |
| Genazzani, AR | 1 |
| Lopez-Rodriguez, AB | 1 |
| Acaz-Fonseca, E | 1 |
| Giatti, S | 1 |
| Caruso, D | 1 |
| Viveros, MP | 1 |
| Melcangi, RC | 1 |
| Garcia-Segura, LM | 2 |
| Arbo, BD | 1 |
| Bennetti, F | 1 |
| Ribeiro, MF | 1 |
| Kilts, JD | 1 |
| Tupler, LA | 1 |
| Keefe, FJ | 1 |
| Payne, VM | 1 |
| Hamer, RM | 1 |
| Naylor, JC | 1 |
| Calnaido, RP | 1 |
| Morey, RA | 1 |
| Strauss, JL | 1 |
| Parke, G | 1 |
| Massing, MW | 1 |
| Youssef, NA | 1 |
| Shampine, LJ | 1 |
| Marx, CE | 1 |
| Malik, AS | 1 |
| Narayan, RK | 1 |
| Wendling, WW | 1 |
| Cole, RW | 1 |
| Pashko, LL | 1 |
| Schwartz, AG | 1 |
| Strauss, KI | 1 |
| Juhász-Vedres, G | 1 |
| Rózsa, E | 1 |
| Rákos, G | 1 |
| Dobszay, MB | 1 |
| Kis, Z | 1 |
| Wölfling, J | 1 |
| Toldi, J | 1 |
| Párducz, A | 1 |
| Farkas, T | 1 |
| García-Estrada, J | 1 |
| Luquín, S | 1 |
| Fernández, AM | 1 |
2 reviews available for dehydroepiandrosterone and Brain Injuries
| Article | Year |
|---|---|
Advances in neurosteroids: role in clinical practice.
Topics: Affect; Aging; Behavior; Brain Injuries; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone S | 2013 |
Astrocytes as a target for neuroprotection: Modulation by progesterone and dehydroepiandrosterone.
Topics: Animals; Astrocytes; Brain Injuries; Dehydroepiandrosterone; Humans; Neuroprotection; Progesterone; | 2016 |
5 other studies available for dehydroepiandrosterone and Brain Injuries
| Article | Year |
|---|---|
Correlation of brain levels of progesterone and dehydroepiandrosterone with neurological recovery after traumatic brain injury in female mice.
Topics: Animals; Behavior, Animal; Body Weight; Brain Chemistry; Brain Edema; Brain Injuries; Dehydroepiandr | 2015 |
Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001.
Topics: Adult; Afghanistan; Brain Injuries; Dehydroepiandrosterone; Female; Gas Chromatography-Mass Spectrom | 2010 |
A novel dehydroepiandrosterone analog improves functional recovery in a rat traumatic brain injury model.
Topics: Animals; Brain; Brain Injuries; Cells, Cultured; Cyclooxygenase 2; Dehydroepiandrosterone; Dinoprost | 2003 |
Dehydroepiandrosterone sulfate is neuroprotective when administered either before or after injury in a focal cortical cold lesion model.
Topics: Animals; Brain Injuries; Cold Temperature; Dehydroepiandrosterone; Drug Administration Schedule; Est | 2006 |
Dehydroepiandrosterone, pregnenolone and sex steroids down-regulate reactive astroglia in the male rat brain after a penetrating brain injury.
Topics: Animals; Astrocytes; Brain Injuries; Cerebral Cortex; Dehydroepiandrosterone; Dentate Gyrus; Estradi | 1999 |