Page last updated: 2024-11-07

dehydroepiandrosterone and Bipolar Disorder

dehydroepiandrosterone has been researched along with Bipolar Disorder in 9 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"The study showed that pregnenolone was significantly decreased in the parietal cortex in the combined group of patients with schizophrenia or bipolar disorder who died by suicide (n = 13) compared with patients with these disorders who died of other causes (n = 17, p = ."3.81Exploratory investigation of biomarker candidates for suicide in schizophrenia and bipolar disorder. ( Allen, TB; Bradford, DW; Brancu, M; Brunca, M; Hamer, RM; Kilts, JD; Marx, CE; Naylor, JC; Shampine, LJ; Strauss, JL; Szabo, ST; Youssef, NA, 2015)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's2 (22.22)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aydin, A1
Selvi, Y1
Besiroglu, L1
Boysan, M1
Atli, A1
Ozdemir, O1
Kilic, S1
Balaharoglu, R1
Vuksan-Ćusa, B1
Sagud, M1
Mihaljević-Peleš, A1
Jakšić, N1
Jakovljević, M1
Youssef, NA1
Bradford, DW1
Kilts, JD1
Szabo, ST1
Naylor, JC1
Allen, TB1
Strauss, JL1
Hamer, RM1
Brancu, M1
Brunca, M1
Shampine, LJ1
Marx, CE1
Lee, SY1
Wang, LJ1
Chang, CH1
Wu, CC1
Chen, HL1
Lin, SH1
Chu, CL1
Lu, T1
Lu, RB1
Gallagher, P1
Watson, S1
Smith, MS1
Young, AH1
Ferrier, IN1
Matsunaga, H1
Sarai, M1
Markowitz, JS1
Carson, WH1
Jackson, CW1
Kline, MD1
Jaggers, ED1
Dean, CE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Changes in Serum miRNA and BDNF Levels in Bipolar II Depression Treated by Theta-burst Stimulation: A Randomized Sham-controlled Exploratory Study[NCT04998097]60 participants (Anticipated)Interventional2022-05-23Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for dehydroepiandrosterone and Bipolar Disorder

ArticleYear
Mood and metabolic consequences of sleep deprivation as a potential endophenotype' in bipolar disorder.
    Journal of affective disorders, 2013, Sep-05, Volume: 150, Issue:2

    Topics: Adult; Affect; Bipolar Disorder; Case-Control Studies; Circadian Rhythm; Dehydroepiandrosterone; End

2013
Metabolic syndrome and cortisol/DHEAS ratio in patients with bipolar disorder and schizophrenia.
    Psychiatria Danubina, 2014, Volume: 26, Issue:2

    Topics: Adult; Bipolar Disorder; Blood Pressure; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Mal

2014
Exploratory investigation of biomarker candidates for suicide in schizophrenia and bipolar disorder.
    Crisis, 2015, Volume: 36, Issue:1

    Topics: Adult; Aged; Autopsy; Biomarkers; Bipolar Disorder; Brain; Case-Control Studies; Chromatography, Hig

2015
Serum DHEA-S concentration correlates with clinical symptoms and neurocognitive function in patients with bipolar II disorder: A case-controlled study.
    Progress in neuro-psychopharmacology & biological psychiatry, 2017, 03-06, Volume: 74

    Topics: Adolescent; Adult; Bipolar Disorder; Case-Control Studies; Cognition; Dehydroepiandrosterone; Dehydr

2017
Plasma cortisol-dehydroepiandrosterone (DHEA) ratios in schizophrenia and bipolar disorder.
    Schizophrenia research, 2007, Volume: 90, Issue:1-3

    Topics: Adult; Age Factors; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Biomarkers; Bipol

2007
Elevated serum LH and androgens in affective disorder related to the menstrual cycle: with reference to polycystic ovary syndrome.
    The Japanese journal of psychiatry and neurology, 1993, Volume: 47, Issue:4

    Topics: Adolescent; Adult; Androgens; Androstenedione; Bipolar Disorder; Dehydroepiandrosterone; Dehydroepia

1993
Possible dihydroepiandrosterone-induced mania.
    Biological psychiatry, 1999, Jan-15, Volume: 45, Issue:2

    Topics: Acute Disease; Adjuvants, Immunologic; Aged; Bipolar Disorder; Dehydroepiandrosterone; Dose-Response

1999
Mania onset while using dehydroepiandrosterone.
    The American journal of psychiatry, 1999, Volume: 156, Issue:6

    Topics: Acute Disease; Bipolar Disorder; Dehydroepiandrosterone; Drug Therapy, Combination; Haloperidol; Hum

1999
Prasterone (DHEA) and mania.
    The Annals of pharmacotherapy, 2000, Volume: 34, Issue:12

    Topics: Adjuvants, Immunologic; Adult; Bipolar Disorder; Dehydroepiandrosterone; Humans; Male

2000