dehydroepiandrosterone has been researched along with Autoimmune Diseases in 12 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Autoimmune Diseases: Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.
| Excerpt | Relevance | Reference |
|---|---|---|
| "16alpha-Hydroxydehydroepiandrosterone is the precursor of fetal 16alpha-hydroxylated estrogens, the main phenolic steroids in pregnancy." | 4.80 | Minireview: 16alpha-hydroxylated metabolites of dehydroepiandrosterone and their biological significance. ( Hampl, R; Starka, L, 2000) |
| "Over 80% of Addison's disease is of the autoimmune type, though almost any systemic destructive process can cause similar steroid insufficiency." | 2.37 | Adrenocortical insufficiency. ( Burke, CW, 1985) |
| " HE3286 is orally bioavailable and treats established disease in models of ulcerative colitis, collagen-induced arthritis, and collagen antibody-induced arthritis, reducing clinical signs of disease and proinflammatory signals, including IL-6 and matrix metallopeptidase 3." | 1.35 | HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease. ( Ahlem, C; Auci, D; Frincke, J; Mangano, K; Nicoletti, F; Reading, C; Stickney, D, 2009) |
| "Our analyses suggest that chronic PTSD, particularly comorbid PTSD or complex PTSD, is associated with all of these conditions." | 1.32 | Posttraumatic stress disorder and physical illness: results from clinical and epidemiologic studies. ( Boscarino, JA, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Namazi, MR | 1 |
| Ahlem, C | 1 |
| Auci, D | 1 |
| Mangano, K | 1 |
| Reading, C | 1 |
| Frincke, J | 1 |
| Stickney, D | 1 |
| Nicoletti, F | 1 |
| Binello, E | 1 |
| Gordon, CM | 1 |
| Arlt, W | 1 |
| Boscarino, JA | 1 |
| Dillon, JS | 1 |
| Bovenberg, SA | 1 |
| van Uum, SH | 1 |
| Hermus, AR | 1 |
| Giordano, R | 1 |
| Balbo, M | 1 |
| Picu, A | 1 |
| Bonelli, L | 1 |
| Berardelli, R | 1 |
| Falorni, A | 1 |
| Ghigo, E | 1 |
| Arvat, E | 1 |
| Dougados, M | 1 |
| Nahoul, K | 1 |
| Benhamou, L | 1 |
| Jungers, P | 1 |
| Laplane, D | 1 |
| Amor, B | 1 |
| Hampl, R | 1 |
| Starka, L | 1 |
| Matsunaga, A | 1 |
| Miller, BC | 1 |
| Cottam, GL | 1 |
| Burke, CW | 1 |
6 reviews available for dehydroepiandrosterone and Autoimmune Diseases
| Article | Year |
|---|---|
Clinical uses and misuses of dehydroepiandrosterone.
Topics: Adjuvants, Immunologic; Autoimmune Diseases; Cardiovascular Diseases; Clinical Trials as Topic; Dehy | 2003 |
Dehydroepiandrosterone replacement therapy.
Topics: Adrenal Insufficiency; Aging; Animals; Autoimmune Diseases; Cognition Disorders; Dehydroepiandroster | 2004 |
Dehydroepiandrosterone, dehydroepiandrosterone sulfate and related steroids: their role in inflammatory, allergic and immunological disorders.
Topics: Aging; Animals; Anti-Inflammatory Agents; Autoimmune Diseases; Cytokines; Dehydroepiandrosterone; De | 2005 |
Dehydroepiandrosterone administration in humans: evidence based?
Topics: Adrenal Insufficiency; Affect; Age Factors; Autoimmune Diseases; Cognition; Dehydroepiandrosterone; | 2005 |
Minireview: 16alpha-hydroxylated metabolites of dehydroepiandrosterone and their biological significance.
Topics: Autoimmune Diseases; Body Fluids; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Estrogens; | 2000 |
Adrenocortical insufficiency.
Topics: Addison Disease; Adrenal Insufficiency; Adrenocorticotropic Hormone; Aldosterone; Androstenedione; A | 1985 |
6 other studies available for dehydroepiandrosterone and Autoimmune Diseases
| Article | Year |
|---|---|
The Th1-promoting effects of dehydroepiandrosterone can provide an explanation for the stronger Th1-immune response of women.
Topics: Autoimmune Diseases; Dehydroepiandrosterone; Estrogens; Female; Gonadal Steroid Hormones; Humans; Im | 2009 |
HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease.
Topics: Administration, Oral; Androstenols; Animals; Autoimmune Diseases; Clinical Trials as Topic; Colitis, | 2009 |
Posttraumatic stress disorder and physical illness: results from clinical and epidemiologic studies.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Dehydroepiandrosterone; Diabetes Mellitus, Type 1; Femal | 2004 |
Corticotrope hypersecretion coupled with cortisol hypo-responsiveness to stimuli is present in patients with autoimmune endocrine diseases: evidence for subclinical primary hypoadrenalism?
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aldosterone; Area Under Curve; Autoantibo | 2006 |
[Study of plasma androgens in women with autoimmune diseases].
Topics: Adolescent; Adult; Androgens; Androstenedione; Arthritis, Rheumatoid; Autoimmune Diseases; Dehydroep | 1984 |
Dehydroisoandrosterone prevention of autoimmune disease in NZB/W F1 mice: lack of an effect on associated immunological abnormalities.
Topics: Animals; Antibody Formation; Autoimmune Diseases; Cells, Cultured; Dehydroepiandrosterone; Fatty Aci | 1989 |