Page last updated: 2024-11-07

dehydroepiandrosterone and Autism

dehydroepiandrosterone has been researched along with Autism in 9 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
"A brief historical background on Autism & some of the important symptoms associated with Autism are summarized."5.42Early Detection of Autism (ASD) by a Non-invasive Quick Measurement of Markedly Reduced Acetylcholine & DHEA and Increased β-Amyloid (1-42), Asbestos (Chrysotile), Titanium Dioxide, Al, Hg & often Coexisting Virus Infections (CMV, HPV 16 and 18), Bacteria ( Duvvi, H; Jones, MK; Lu, D; Nihrane, A; Ohki, M; Omura, Y; Shimotsuura, Y, 2015)
"The prevalence of autism spectrum disorders (ASDs) is 1 in 300 children in the US."5.33A clinical and laboratory evaluation of methionine cycle-transsulfuration and androgen pathway markers in children with autistic disorders. ( Geier, DA; Geier, MR, 2006)
"The aim of this study was to determine for the first time neurosteroid levels, dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEA-S) in particular, in a group of adult patients with autistic disorder and compare these levels with normal healthy individuals."3.73Lowered DHEA-S plasma levels in adult individuals with autistic disorder. ( Golubchik, P; Maayan, R; Mozes, T; Spivak, B; Strous, RD; Tuati-Werner, D; Weizman, A, 2005)
"A brief historical background on Autism & some of the important symptoms associated with Autism are summarized."1.42Early Detection of Autism (ASD) by a Non-invasive Quick Measurement of Markedly Reduced Acetylcholine & DHEA and Increased β-Amyloid (1-42), Asbestos (Chrysotile), Titanium Dioxide, Al, Hg & often Coexisting Virus Infections (CMV, HPV 16 and 18), Bacteria ( Duvvi, H; Jones, MK; Lu, D; Nihrane, A; Ohki, M; Omura, Y; Shimotsuura, Y, 2015)
"Because of the nature of autism, these young people have difficulty navigating the challenges of school and adolescence."1.39The effectiveness of narrative therapy with young people with autism. ( Bradbury, J; Browne, G; Cashin, A; Mulder, A, 2013)
"Children with autism are known to have larger head circumferences; whether they are above average in height and weight is less clear."1.34Elevated levels of growth-related hormones in autism and autism spectrum disorder. ( Brasington, M; Chrousos, GP; England, LJ; Hediger, ML; Manning-Courtney, P; Mills, JL; Molloy, CA; Yu, KF, 2007)
"The prevalence of autism spectrum disorders (ASDs) is 1 in 300 children in the US."1.33A clinical and laboratory evaluation of methionine cycle-transsulfuration and androgen pathway markers in children with autistic disorders. ( Geier, DA; Geier, MR, 2006)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's4 (44.44)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
El-Baz, F1
Hamza, RT1
Ayad, MS1
Mahmoud, NH1
Omura, Y1
Lu, D1
Jones, MK1
Nihrane, A1
Duvvi, H1
Shimotsuura, Y1
Ohki, M1
Trent, S1
Dean, R1
Veit, B1
Cassano, T1
Bedse, G1
Ojarikre, OA1
Humby, T1
Davies, W1
Cashin, A1
Browne, G1
Bradbury, J1
Mulder, A1
Strous, RD1
Golubchik, P1
Maayan, R1
Mozes, T1
Tuati-Werner, D1
Weizman, A1
Spivak, B1
Geier, DA2
Geier, MR2
Mills, JL1
Hediger, ML1
Molloy, CA1
Chrousos, GP1
Manning-Courtney, P1
Yu, KF1
Brasington, M1
England, LJ1
Tordjman, S1
Anderson, GM1
McBride, PA1
Hertzig, ME1
Snow, ME1
Hall, LM1
Ferrari, P1
Cohen, DJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multi-center, Prospective, Cohort Study to Elucidate the Effects of Metformin Treatment on Steroid Hormones and Social Behavior. Linking Autistic Behaviorial Symptoms to Changes in Steroid Hormone Availability[NCT04930471]45 participants (Anticipated)Observational2021-06-30Not yet recruiting
Investigation of Urinary Steroid Metabolites in Children With Autism Spectrum Disorder[NCT01197131]160 participants (Actual)Observational2010-09-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for dehydroepiandrosterone and Autism

ArticleYear
Hyperandrogenemia in male autistic children and adolescents: relation to disease severity.
    International journal of adolescent medicine and health, 2014, Volume: 26, Issue:1

    Topics: Adolescent; Androgens; Androstenedione; Autistic Disorder; Child; Cross-Sectional Studies; Dehydroep

2014
Early Detection of Autism (ASD) by a Non-invasive Quick Measurement of Markedly Reduced Acetylcholine & DHEA and Increased β-Amyloid (1-42), Asbestos (Chrysotile), Titanium Dioxide, Al, Hg & often Coexisting Virus Infections (CMV, HPV 16 and 18), Bacteria
    Acupuncture & electro-therapeutics research, 2015, Volume: 40, Issue:3

    Topics: Acetylcholine; Adolescent; Aluminum; Amyloid beta-Peptides; Asbestos; Autistic Disorder; Bacterial I

2015
Biological mechanisms associated with increased perseveration and hyperactivity in a genetic mouse model of neurodevelopmental disorder.
    Psychoneuroendocrinology, 2013, Volume: 38, Issue:8

    Topics: Acetylserotonin O-Methyltransferase; Animals; Appetitive Behavior; Attention Deficit Disorder with H

2013
The effectiveness of narrative therapy with young people with autism.
    Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc, 2013, Volume: 26, Issue:1

    Topics: Adolescent; Autistic Disorder; Biomarkers; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; M

2013
Lowered DHEA-S plasma levels in adult individuals with autistic disorder.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2005, Volume: 15, Issue:3

    Topics: Adult; Autistic Disorder; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hy

2005
A clinical and laboratory evaluation of methionine cycle-transsulfuration and androgen pathway markers in children with autistic disorders.
    Hormone research, 2006, Volume: 66, Issue:4

    Topics: Androgens; Autistic Disorder; Biomarkers; Child; Child, Preschool; Cystathionine; Cysteine; Dehydroe

2006
Elevated levels of growth-related hormones in autism and autism spectrum disorder.
    Clinical endocrinology, 2007, Volume: 67, Issue:2

    Topics: Adrenal Glands; Autistic Disorder; Body Mass Index; Body Weight; Carrier Proteins; Case-Control Stud

2007
A prospective assessment of androgen levels in patients with autistic spectrum disorders: biochemical underpinnings and suggested therapies.
    Neuro endocrinology letters, 2007, Volume: 28, Issue:5

    Topics: Adolescent; Adult; Age Factors; Androstenedione; Autistic Disorder; Case-Control Studies; Child; Deh

2007
Plasma androgens in autism.
    Journal of autism and developmental disorders, 1995, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Autistic Disorder; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepiand

1995